The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Patient burden and quality of life in atopic dermatitis in US adults
Open accessAbstract
BACKGROUND: The patient burden and quality of life (QOL) impact of atopic dermatitis (AD) in the United States population is not well established. OBJECTIVE: To elucidate the patient burden of AD in the US population. METHODS: A cross-sectional, population-based study of 602 adults was performed. Atopic dermatitis was determined using modified UK Diagnostic Criteria for AD. Its severity was assessed using self-reported global AD severity, Patient-Oriented Eczema Measure (POEM), Patient-Oriented Scoring AD (PO-SCORAD), PO-SCORAD-itch, and sleep. Quality of life was assessed using short-form (SF-)12 mental and physical health scores and Dermatology Life Quality Index (DLQI). RESULTS: Adults with AD reported higher proportions of having only fair/poor overall health (25.8% vs. 15.8%), being somewhat/very dissatisfied with life (16.7% vs 11.4%), lower weighted mean (standard deviation [SD]) SF-12 mental (45.9 [9.9] vs 50.9 [9.2]) and physical health subscores (53.0 [2.5] vs 53.5 [2.3]) and higher DLQI (4.9 [6.5] vs 1.1 [2.8]). In multivariable regression models adjusting for sociodemographics and multiple comorbid health disorders, significant stepwise decreases by AD severity (self-reported, POEM, PO-SCORAD) of overall health, life satisfaction, SF-12 mental health, and increases of DLQI scores were seen. The SF-12 physical health scores were only associated with moderate AD. Concurrently, severe PO-SCORAD, POEM, or PO-SCORAD-itch was associated with very low mean SF-12 mental health (34.7) and high DLQI scores (24.7). Atopic dermatitis commonly limited lifestyle (51.3%), led to avoidance of social interaction (39.1%), and impacted activities (43.3%). The most burdensome AD symptoms were itch (54.4%), excessive dryness/scaling (19.6%), and red/inflamed skin (7.2%). CONCLUSION: These data support the heavy burden that AD places on patients, particularly those with moderate and severe AD.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing
Benjamini, Y., & Hochberg, Y. (1995) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1995.tb02031.x · Cited by 109,482
WARE, J. E., KOSINSKI, M., & KELLER, S. D. (1996) · Medical Care · doi:10.1097/00005650-199603000-00003 · Cited by 17,392
Dermatology Life Quality Index (DLQI)-a simple practical measure for routine clinical use
FINLAY, A. Y., & KHAN, G. K. (1994) · Clinical and Experimental Dermatology · doi:10.1111/j.1365-2230.1994.tb01167.x · Cited by 5,586
WILLIAMS, H. C., JBURNEY, P. G., PEMBROKE, A. C., HAY, R. J., & Party, A. D. D. C. W. (1994) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1994.tb08532.x · Cited by 926
Basra, M. K. A., Fenech, R., Gatt, R. M., Salek, M. S., & Finlay, A. Y. (2008) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2008.08832.x · Cited by 789
Development and Testing of the UK SF-12
Jenkinson, C., & Layte, R. (1997) · Journal of Health Services Research & Policy · doi:10.1177/135581969700200105 · Cited by 493
Increasing Comorbidities Suggest that Atopic Dermatitis Is a Systemic Disorder
Brunner, P. M., Silverberg, J. I., Guttman-Yassky, E., Paller, A. S., Kabashima, K., Amagai, M., Luger, T. A., Deleuran, M., Werfel, T., Eyerich, K., et al. (2017) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2016.08.022 · Cited by 377
Self-citationUse of Internet panels to conduct surveys
Hays, R. D., Liu, H., & Kapteyn, A. (2015) · Behavior Research Methods · doi:10.3758/s13428-015-0617-9 · Cited by 341
Silverberg, J. I., & Simpson, E. L. (2013) · Pediatric Allergy and Immunology · doi:10.1111/pai.12095 · Cited by 310
Self-citationSimpson, E. L., Bieber, T., Eckert, L., Wu, R., Ardeleanu, M., Graham, N. M. H., Pirozzi, G., & Mastey, V. (2016) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2015.10.043 · Cited by 302
Self-citation
Cited by
Molecular Mechanisms of Atopic Dermatitis Pathogenesis
Sroka-Tomaszewska, J., & Trzeciak, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22084130 · Cited by 577
Atopic dermatitis in the pediatric population
Silverberg, J. I., Barbarot, S., Gadkari, A., Simpson, E. L., Weidinger, S., Mina-Osorio, P., Rossi, A. B., Brignoli, L., Saba, G., Guillemin, I., et al. (2021) · Annals of Allergy, Asthma & Immunology · doi:10.1016/j.anai.2020.12.020 · Cited by 459
Self-citationComorbidities and the impact of atopic dermatitis
Silverberg, J. I. (2019) · Annals of Allergy, Asthma & Immunology · doi:10.1016/j.anai.2019.04.020 · Cited by 431
Self-citationSilverberg, J. I., Simpson, E. L., Thyssen, J. P., Gooderham, M., Chan, G., Feeney, C., Biswas, P., Valdez, H., DiBonaventura, M., Nduaka, C., et al. (2020) · JAMA Dermatology · doi:10.1001/jamadermatol.2020.1406 · Cited by 404
Self-citationJAK inhibitors in the treatment of atopic dermatitis
Chovatiya, R., & Paller, A. S. (2021) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2021.08.009 · Cited by 398
Metadata
- Authors
- Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Simpson, E. L., Ong, P. Y., & Chiesa Fuxench, Z. C.
- Venue
- Annals of Allergy, Asthma & Immunology
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 121
- Issue
- 3
- Pages
- 340-347
- ISSN
- 1081-1206 (ISSN-L)
- OpenAlex
- W2883568898
- Cited by
- 648
- References
- 35
- FWCI
- 42.73
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Patient burden and quality of life in atopic dermatitis in US adults. https://app.cochat.ai/papers/10.1016/j.anai.2018.07.006
- The paper
- Silverberg, J. I., Gelfand, J. M., Margolis, D. J., Boguniewicz, M., Fonacier, L., Grayson, M. H., Simpson, E. L., Ong, P. Y., & Chiesa Fuxench, Z. C. (2018). Patient burden and quality of life in atopic dermatitis in US adults. Annals of Allergy, Asthma & Immunology. https://doi.org/10.1016/j.anai.2018.07.006
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
