The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Atopic dermatitis in the pediatric population
Open accessAbstract
BACKGROUND: Little is known on the current global prevalence of atopic dermatitis (AD) in the pediatric population. OBJECTIVE: To estimate the real-world global prevalence of AD in the pediatric population and by disease severity. METHODS: This international, cross-sectional, web-based survey of children and adolescents (6 months to <18 years old) was conducted in the following 18 countries: North America (Canada, United States), Latin America (Argentina, Brazil, Columbia, Mexico), Europe (France, Germany, Italy, Spain, United Kingdom), Middle East and Eurasia (Israel, Saudi Arabia, Turkey, United Arab Emirates, Russia), and East Asia (Japan, Taiwan). Prevalence was determined using the following 2 definitions: (1) diagnosed as having AD according to the International Study of Asthma and Allergies in Childhood (ISAAC) criteria and self- or parent-report of ever being told by a physician that they or their child child had AD (eczema); and (2) reported AD based on the ISAAC criteria only. Severity was assessed using the Patient Global Assessment (PtGA) and Patient-Oriented Eczema Measure (POEM). RESULTS: Among 65,661 responders, the 12-month diagnosed AD prevalence (ISAAC plus self-reported diagnosis) ranged from 2.7% to 20.1% across countries; reported AD (ISAAC only) was 13.5% to 41.9%. Severe AD evaluated with both PtGA and POEM was generally less than 15%; more subjects rated AD as mild on PtGA than suggested by POEM. No trends in prevalence were observed based on age or sex; prevalence was generally lower in rural residential settings than urban or suburban. CONCLUSION: This global survey in 18 countries revealed that AD affects a substantial proportion of the pediatric population. Although prevalence and severity varied across age groups and countries, less than 15% had severe AD.
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Cites
Williams, H. C., Leung, D. Y. M., Thestrup‐Pedersen, K., & David, T. J. (2000) · Cited by 4,596
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International Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods
Asher, M., Keil, U., Anderson, H., Beasley, R., Crane, J., Martinez, F., Mitchell, E., Pearce, N., Sibbald, B., Stewart, A., et al. (1995) · European Respiratory Journal · doi:10.1183/09031936.95.08030483 · Cited by 3,724
Beasley, R. (1998) · The Lancet · doi:10.1016/s0140-6736(97)07302-9 · Cited by 3,389
Atopic Dermatitis: Global Epidemiology and Risk Factors
Nutten, S. (2015) · Annals of Nutrition and Metabolism · doi:10.1159/000370220 · Cited by 3,055
Williams, H., Robertson, C., Stewart, A., Aït-Khaled, N., Anabwani, G., Anderson, R., Asher, I., Beasley, R., Björkstén, B., Burr, M., et al. (1999) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(99)70536-1 · Cited by 998
Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three
Odhiambo, J. A., Williams, H. C., Clayton, T. O., Robertson, C. F., & Asher, M. I. (2009) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2009.10.009 · Cited by 966
Epidemiology of atopic dermatitis in adults: Results from an international survey
Barbarot, S., Auziere, S., Gadkari, A., Girolomoni, G., Puig, L., Simpson, E. L., Margolis, D. J., de Bruin‐Weller, M., & Eckert, L. (2018) · Allergy · doi:10.1111/all.13401 · Cited by 876
Self-citationEczema Prevalence in the United States: Data from the 2003 National Survey of Children's Health
Shaw, T. E., Currie, G. P., Koudelka, C. W., & Simpson, E. L. (2011) · Journal of Investigative Dermatology · doi:10.1038/jid.2010.251 · Cited by 719
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Atopic dermatitis: an expanding therapeutic pipeline for a complex disease
Bieber, T. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00266-6 · Cited by 623
Chu, D. K., Schneider, L., Asiniwasis, R. N., Boguniewicz, M., De Benedetto, A., Ellison, K., Frazier, W. T., Greenhawt, M., Huynh, J., Kim, E., et al. (2024) · Annals of Allergy, Asthma & Immunology · doi:10.1016/j.anai.2023.11.009 · Cited by 380
Self-citationKim, K., Jang, H., Kim, E., Kim, H., & Sung, G. Y. (2023) · Experimental Dermatology · doi:10.1111/exd.14940 · Cited by 24
Liu, L., Liu, C., Chen, R., Feng, R., Zhou, Y., Wang, L., Hong, J., Cao, L., Lu, Y., Dong, X., et al. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.117231 · Cited by 9
The (one‐year) prevalence of atopic dermatitis in Brazil: A population‐based telephone survey
Miot, H. A., Aoki, V., Orfali, R. L., Solé, D., Mallozi, M. C., Rodrigues, T. C., & Silverberg, J. I. (2023) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.19071 · Cited by 8
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Metadata
- Authors
- Silverberg, J. I., Barbarot, S., Gadkari, A., Simpson, E. L., Weidinger, S., Mina-Osorio, P., Rossi, A. B., Brignoli, L., Saba, G., Guillemin, I., Fenton, M. C., Auziere, S., & Eckert, L.
- Venue
- Annals of Allergy, Asthma & Immunology
- Publisher
- Elsevier BV
- Published
- 2021-04
- Volume
- 126
- Issue
- 4
- Pages
- 417-428.e2
- ISSN
- 1081-1206 (ISSN-L)
- OpenAlex
- W3119334612
- Cited by
- 459
- References
- 39
- FWCI
- 52.43
- Type
- journal article
- Language
- en
- Open access
- hybrid
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