The DOI matches its Crossref record; 192 of the 192 references it cites were found in a registry or an index.
Plant-derived anticancer agents: A green anticancer approach
Open accessAbstract
Cancer is a frightful disease and represents one of the biggest health-care issues for the human race and demands a proactive strategy for cure. Plants are reservoirs for novel chemical entities and provide a promising line for research on cancer. Hitherto, being effective, chemotherapy is accompanied by certain unbearable side effects. Nevertheless, plants and plant derived products is a revolutionizing field as these are Simple, safer, eco-friendly, low-cost, fast, and less toxic as compared with conventional treatment methods. Phytochemicals are selective in their functions and acts specifically on tumor cells without affecting normal cells. Carcinogenesis is complex phenomena that involves many signaling cascades. Phytochemicals are considered suitable candidates for anticancer drug development due to their pleiotropic actions on target events with multiple manners. The research is in progress for developing potential candidates (those can block or slow down the growth of cancer cells without any side effects) from these phytochemicals. Many phytochemicals and their derived analogs have been identified as potential candidates for anticancer therapy. Effort has been made through this comprehensive review to highlight the recent developments and milestones achieved in cancer therapies using phytomolecules with their mechanism of action on nuclear and cellular factors. Furthermore, drugs for cancer treatment and their limitations have also been discussed.
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1 retracted
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Cited by
Status and Challenges of Plant-Anticancer Compounds in Cancer Treatment
Garcia-Oliveira, P., Otero, P., Pereira, A. G., Chamorro, F., Carpena, M., Echave, J., Fraga-Corral, M., Simal-Gandara, J., & Prieto, M. A. (2021) · Pharmaceuticals · doi:10.3390/ph14020157 · Cited by 303
Therapeutic strategies to overcome taxane resistance in cancer
Das, T., Anand, U., Pandey, S. K., Ashby, C. R., Assaraf, Y. G., Chen, Z.-S., & Dey, A. (2021) · Drug Resistance Updates · doi:10.1016/j.drup.2021.100754 · Cited by 253
Bioactive compounds and their future therapeutic applications
Shrinet, K., Singh, R. K., Chaurasia, A. K., Tripathi, A., & Kumar, A. (2021) · Natural Bioactive Compounds · doi:10.1016/b978-0-12-820655-3.00017-3 · Cited by 62
GHENABZİA, I., HEMMAMİ, H., BEN AMOR, I., ZEGHOUD, S., BEN SEGHİR, B., & HAMMOUDİ, R. (2023) · International Journal of Secondary Metabolite · doi:10.21448/ijsm.1225936 · Cited by 51
Metadata
- Authors
- Iqbal, J., Abbasi, B. A., Mahmood, T., Kanwal, S., Ali, B., Shah, S. A., & Khalil, A. T.
- Venue
- Asian Pacific Journal of Tropical Biomedicine
- Published
- 2017-12
- Volume
- 7
- Issue
- 12
- Pages
- 1129-1150
- ISSN
- 2221-1691 (ISSN-L)
- OpenAlex
- W2772110171
- Cited by
- 685
- References
- 192
- FWCI
- 41.19
- Type
- journal article
- Language
- en
- Open access
- diamond
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- Iqbal, J., Abbasi, B. A., Mahmood, T., Kanwal, S., Ali, B., Shah, S. A., & Khalil, A. T. (2017). Plant-derived anticancer agents: A green anticancer approach. Asian Pacific Journal of Tropical Biomedicine. https://doi.org/10.1016/j.apjtb.2017.10.016
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
