Cited by 2Cardiac Arrest and ResuscitationSimulation-Based Education in HealthcareInnovations in Medical Education

Aprendizaje combinado frente a realidad virtual y métodos tradicionales en la formación en reanimación cardiopulmonar: un ensayo aleatorizado en estudiantes universitarios

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Ocampo Cervantes, Ana Belén, Greif, Robert, Castro Delgado, Rafael, López López, Carmen Amalia, Carrión García, Eduardo, Pardo Ríos, Manuel·2026·Atención Primaria

Abstract

OBJECTIVE: Out-of-hospital cardiac arrest is the leading cause of sudden death. Basic Life Support (BLS) training is an essential competency in Nursing. Active learning methodologies such as blended learning may improve educational outcomes. DESIGN: A randomized controlled trial with four parallel groups (n=160). PARTICIPANTS: was conducted among first-year undergraduate nursing students. Site: At a university in the Region of Murcia, Spain. INTERVENTIONS: Four methodologies were compared: traditional training, virtual reality (VR), blended learning, and a control group with no intervention. Practical competence was assessed using an 8-item checklist covering key steps in the chain of survival. Technical parameters were measured using Laerdal QCPR® manikins, including percentage of high-quality CPR, compression depth, rate, and full chest recoil. ANOVA, chi-square tests, and correlation models were applied (p<0.05). RESULTS: Practical competence differed significantly between groups (p<0.001). MAIN MEASUREMENTS: The blended and traditional groups achieved the highest scores (6.6±1.7 and 6.6±1.5, respectively), followed by the VR group (6.3±1.5) and the control group (3.1±1.5). Mean CPR quality also differed significantly (p=0.0045), with the blended group showing the highest percentage (72.3%), followed by traditional (65.4%), VR (63.4%), and control (46.9%). Regarding compression depth (p=0.0011), the blended and VR groups achieved similar results (6.1cm), outperforming the traditional (5.5cm) and control (4.8cm) groups. Perceived usability of the VR system was high (78/100). CONCLUSIONS: Blended learning showed overall better performance in most variables analyzed, with higher CPR quality and equal or superior results in practical competence and compression depth compared to the traditional and immersive models. These findings support its effectiveness as a teaching strategy for acquiring BLS competencies.

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  1. [1]Berdowski J. Berg R.A. Tijssen J.G. Koster R.W. Global incidences of out-of-hospital cardiac arrest and survival rates: Systematic review of 67 prospective studies Resuscitation. 81 2010 1479 1487 20828914
  2. [2]Grasner J.-T. Herlitz J. Tjelmeland I.B.M. Wnent J. Masterson S. Lilja G. European Resuscitation Council Guidelines 2021: Epidemiology of cardiac arrest in Europe Resuscitation 161 2021 61 79 33773833
  3. [3]Greif R. Lockey A. Breckwoldt J. Carmona F. Conaghan P. Kuzovlev A. European Resuscitation Council Guidelines 2021: Education Resuscitation. 161 2021 388 407 33773831
  4. [4]Elgohary M. Palazzo F.S. Breckwoldt J. Cheng A. Pellegrino J. Schnaubelt S. Blended learning for accredited life support courses - A systematic review Resusc Plus. 10 2022 100240 10.1016/j.resplu.2022.100240 PMID: 35592876; PMCID: PMC9112020 35592876 PMC9112020 · DOI
  5. [5]Vallée A. Blacher J. Cariou A. Sorbets E. Blended learning compared to traditional learning in medical education: Systematic review and meta-analysis J Med Internet Res. 22 2020 e16504 PMC7445617 32773378
  6. [6]Liu Q. Peng W. Zhang F. Hu R. Li Y. Yan W. The effectiveness of blended learning in health professions: Systematic review and meta-analysis J Med Internet Res. 18 2016 e2 26729058 PMC4717286
  7. [8]Flaschenberger I. Lee D. Palmer E. Immersive Opportunities: A systematic review of virtual reality in the classroom Barbieri W. Palmer E. Risks and Opportunities in Using Educational Technologies. 2025 SpringerBriefs in Education 87 107
  8. [9]Finn Y. Smyth S. Twelve tips for integrating Virtual Reality Simulation into Health Professions Curricula MedEdPublish. 14 2024 233 39554244 PMC11568370
  9. [11]Cheng A. Nadkarni V.M. Mancini M.B. Hunt E. Sinz E. Merchant R. Circulation. 138 2018 e82 e122 29930020
  10. [12]ILCOR. Education, Implementation and Teams 2020 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations Resuscitation 156 2020 A78 A106 33098918
  11. [13]Schulz K.F. Altman D.G. Moher D. CONSORT Group CONSORT 2010 Statement: Updated guidelines for reporting parallel group randomised trials BMJ. 340 2010 c332 20332509 PMC2844940
  12. [15]Schroeder D.C. Semeraro F. Greif R. Bray J. Morley P. Parr M. KIDS SAVE LIVES: Basic Life Support Education for Schoolchildren: A Narrative Review and Scientific Statement From the International Liaison Committee on Resuscitation Resuscitation. 188 2023 109772 10.1016/j.resuscitation.2023.109772 Epub 2023 May 17. PMID: 37190748 · DOI
  13. [16]Kim K.J. Kim G. Effectiveness of e-learning in medical education: a systematic review Korean J Med Educ. 31 2019 19 27
  14. [17]Means B. Toyama Y. Murphy R. Bakia M. Jones K. Evaluation of Evidence-Based Practices in Online Learning: A Meta-Analysis and Review of Online Learning Studies US Department of Education 2010
  15. [18]Hew K.F. Lo C.K. Flipped classroom improves student learning in health professions education: a meta-analysis BMC Med Educ. 18 2018 38 29544495 PMC5855972
  16. [19]Nishiyama C. Iwami T. Murakami Y. Kitamura T. Okamoto Y. Marukawa S. Effectiveness of a simplified chest compression–only CPR training program for children Resuscitation. 90 2015 56 60 25724354
  17. [26]Semeraro F. Greif R. Böttiger B. Burkart R. Cimpoesu D. Georgiou M. Resuscitation. 161 2021 80 97 33773834
  18. [27]Semeraro F. Imbriaco G. Del Giudice D. Antognoli M. Celin D. Cuttitta M. Empowering the next Generation: An innovative “Kids Save Lives” blended learning programme for schoolchildren training Resuscitation. 194 2024 110088 38101506
  19. [28]Cheng A. Lockey A. Bhanji F. Lin Y. Hunt E.A. Land E. The use of high-fidelity simulation for training in pediatric resuscitation: A systematic review and meta-analysis Resuscitation. 93 2015 142 149 25888241
  20. [30]Gaba D.M. The future vision of simulation in healthcare Simul Healthc. 2 2007 126 135 19088617
  21. [32]Issenberg S.B. McGaghie W.C. Petrusa E.R. Gordon D.L. Scalese R.J. Features and uses of high-fidelity medical simulations that lead to effective learning: a BEME systematic review Med Teach. 27 2005 10 28 16147767
  22. [33]Rowe M. Frantz J. Bozalek V. The role of blended learning in health professional education: an integrative review Med Teach. 34 2012 e216 e221 10.3109/0142159X. 2012.642831 22455712 · DOI
  23. [34]Li M. Hong Y. Wu A. Ou W. Yang J. Lin G. The effectiveness of blended learning in nursing and medical education: An umbrella review Nurse Educ Pract. 86 2025 104421 40483931
  24. [35]Makransky G. Mayer R.E. Benefits of immersive virtual reality in learning environments: a meta-analysis Educ Psychol Rev. 34 2022 2019 2048 PMC9023331 35475019

Authors
Ocampo Cervantes, A. B., Greif, R., Castro Delgado, R., López López, C. A., Carrión García, E., & Pardo Ríos, M.
Affiliations
University of Bern (CH)
Venue
Atención Primaria
Publisher
Elsevier BV
Published
2026-02
Volume
58
Issue
2
Pages
103413
ISSN
0212-6567 (ISSN-L)
OpenAlex
W7118185856
Cited by
2
References
0
Citations by year
2026: 2
FWCI
13.43
Type
journal article
Language
es
Open access
Locations
  • Atención Primaria (publishedVersion, cc-by-nc-nd)
  • PubMed (publishedVersion)
  • PubMed Central (publishedVersion, cc-by-nc-nd)
Funders
Gobierno de Espana Ministerio de Ciencia e Innovacion
Topics
  • Health Sciences › Medicine › Emergency Medicine › Cardiac Arrest and Resuscitation
  • Health Sciences › Medicine › Physiology › Simulation-Based Education in Healthcare
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Innovations in Medical Education
Keywords
CPR training, basic life support, virtual reality, blended learning, nursing education, out-of-hospital cardiac arrest, CPR quality, compression depth, chain of survival, practical skills, undergraduate nursing students
MeSH terms
Virtual Reality, Adult, Education, Nursing, Female, Humans, Male, Students, Nursing, Universities, Cardiopulmonary Resuscitation, Young Adult

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