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Cited by 282

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Whole-body cortisol response of zebrafish to acute net handling stress

Open access
Ramsay, Jennifer M., Feist, Grant W., Varga, Zoltán M., Westerfield, Monte, Kent, Michael L., Schreck, Carl B.·2009·Aquaculture

Abstract

Zebrafish, Danio rerio, are frequently handled during husbandry and experimental procedures in the laboratory, yet little is known about the physiological responses to such stressors. We measured the whole-body cortisol levels of adult zebrafish subjected to net stress and air exposure at intervals over a 24 h period; cortisol recovered to near control levels by about 1 h post-net-stress (PNS). We then measured cortisol at frequent intervals over a 1 h period. Cortisol levels were more than 2-fold higher in net stressed fish at 3 min PNS and continued to increase peaking at 15 min PNS, when cortisol levels were 6-fold greater than the control cortisol. Mean cortisol declined from 15 to 60 min PNS, and at 60 min, net-stressed cortisol was similar to control cortisol. Because the age of fish differed between studies, we examined resting cortisol levels of fish of different ages (3, 7, 13, and 19 months). The resting cortisol values among tanks with the same age fish differed significantly but there was no clear effect of age. Our study is the first to report the response and recovery of cortisol after net handling for laboratory-reared zebrafish.

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Crossref · 10.1016/j.aquaculture.2009.08.035

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Metadata

Authors
Ramsay, J. M., Feist, G. W., Varga, Z. M., Westerfield, M., Kent, M. L., & Schreck, C. B.
Venue
Aquaculture
Publisher
Elsevier BV
Published
2009-12
Volume
297
Issue
1-4
Pages
157-162
ISSN
0044-8486 (ISSN-L)
OpenAlex
W1967260964
Cited by
282
References
41
FWCI
2.21
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Whole-body cortisol response of zebrafish to acute net handling stress. https://app.cochat.ai/papers/10.1016/j.aquaculture.2009.08.035
The paper
Ramsay, J. M., Feist, G. W., Varga, Z. M., Westerfield, M., Kent, M. L., & Schreck, C. B. (2009). Whole-body cortisol response of zebrafish to acute net handling stress. Aquaculture. https://doi.org/10.1016/j.aquaculture.2009.08.035

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.