Biochemical Responses of Mytilus galloprovincialis as Biomarkers of Acute Environmental Pollution Caused by the Don Pedro Oil Spill (Eivissa Island, Spain)
Open accessAbstract
In the present work, the potential use of several antioxidant and detoxification biomarkers in the digestive gland of wild mussels (Mytilus galloprovincialis) for biomonitoring the marine pollution induced by the Don Pedro oil spill has been investigated. Two locations from the East to South-East of Eivissa (Ibiza) and Formentera islands were selected, one extensively affected by the oil spill and the other one not affected and considered as the control area. Mussels were sampled one, two and six months after the Don Pedro accident. Polycyclic aromatic hydrocarbon (PAH) levels were significantly increased in the soft tissues of mussels in the affected area one month after the disaster, returning to normal values after six months. Markers of oxidative damage in lipids--malondialdehyde, and in proteins--carbonyl derivates, and antioxidant enzyme--catalase, superoxide dismutase and glutathione peroxidase, activities significantly increased as result of the spill oil after one month, returning to basal values at two month sampling time. Glutathione/glutathione disulfide ratio (GSH/GSSG), as a marker of the redox status, was reduced after one and two months indicating a more oxidized situation. Markers of detoxification--glutathione-S-transferase and cytochrome P4501A activities and metallothionein gene expression--were significantly increased by the oil spill one month after the accident, returning to the basal values at two month sampling time. In conclusion, the Don Pedro accident induced a transient situation of PAHs pollution resulting in enhanced antioxidant and detoxification defense systems in the wild mussel M. galloprovincialis returning to normal levels six months from the spill. The selected biomarkers are a useful tool for biomonitoring the response to acute exposure to pollutants in marine mussels.
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- Authors
- Sureda, A., Box, A., Tejada, S., Blanco, A., Caixach, J., & Deudero, S.
- Affiliations
- Universitat de les Illes Balears (ES)
- Hospital Son Llatzer (ES)
- Consejo Superior de Investigaciones Científicas (ES)
- Instituto Español de Oceanografía (ES)
- Corresponding author
- Sureda, Antoni
- Venue
- Aquatic Toxicology
- Publisher
- Elsevier BV
- Published
- 2011-02
- Volume
- 101
- Issue
- 3-4
- Pages
- 540-549
- ISSN
- 0166-445X (ISSN-L)
- OpenAlex
- W2018803549
- Cited by
- 145
- References
- 59
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 4 · 2023: 7 · 2022: 11 · 2021: 14 · 2020: 8 · 2019: 10 · 2018: 14 · 2017: 12 · 2016: 13 · 2015: 18 · 2014: 9 · 2013: 11 · 2012: 5
- FWCI
- 4.15
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- cc-by-nc-nd
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Aquatic Toxicology (publishedVersion)
- PubMed (publishedVersion)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by-nc-nd)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion)
- Funders
- Govern de les Illes Balears
- Topics
- Physical Sciences › Environmental Science › Health, Toxicology and Mutagenesis › Environmental Toxicology and Ecotoxicology
- Physical Sciences › Environmental Science › Pollution › Oil Spill Detection and Mitigation
- Physical Sciences › Engineering › Ocean Engineering › Marine Biology and Environmental Chemistry
- Keywords
- Mytilus galloprovincialis, marine oil pollution, biomonitoring, antioxidant enzymes, detoxification enzymes, polycyclic aromatic hydrocarbons, oxidative stress, lipid peroxidation, protein carbonylation, glutathione disulfide, glutathione S-transferase, CYP1A, metallothionein, digestive gland, Ibiza
- MeSH terms
- Analysis of Variance, Animals, Catalase, Disasters, Environmental Monitoring, Environmental Pollutants, Glutathione Peroxidase, Malondialdehyde, Petroleum, Polycyclic Aromatic Hydrocarbons, Spain, Superoxide Dismutase, Time Factors, Biomarkers, DNA Primers, Gastrointestinal Tract, Mytilus
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