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Cited by 51Skin Protection and AgingAndrographolide Research and ApplicationsMedicinal Plant Research

New potential and characterization of Andrographis paniculata L. Ness plant extracts as photoprotective agent

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Fardiyah, Qonitah, Ersam, Taslim, Suyanta, Slamet, Agus, Suprapto, Kurniawan, Fredy·2020·Arabian Journal of Chemistry
DOI 10.1016/j.arabjc.2020.10.015
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Abstract

The species Andrographis paniculata L. Ness, family Acanthaceae grows in many parts in the island of Java in Indonesia. In this research, new potentials of photoprotective agents from A. paniculata plant extracts, along with their characteristics, were investigated. The phytochemical test, infrared analysis, ultraviolet characterization, fluorescence identification, flavonoid content by thin layer chromatography, high performance liquid chromatography-mass spectrometry (LCMS/MS) and photoprotective analysis were performed in the extracts. The new potentials of A. paniculata plant extracts were studied at various concentrations of extracts and shown by the value of the sun protection factor (SPF). Based on phytochemical test, A. paniculata plant extracts contained flavonoids, alkaloids, tannins, triterpenoids and polyphenols. A. paniculata plant extracts have 2 maximum wavelengths at 230 nm and 362 nm. The excitation peak at 300 nm (552.11 a.u) and the emission peak at 605 nm (516.02 a.u). The flavonoid content of the extracts was 0.022 µg/mL quercetin with Rf value of 0.61. The chromatogram of the LCMS/MS is similar to quercetin-3-glycoside standard at a retention time of 2.77. The photoprotective activity of A. paniculata plant extracts had ≥ 15 SPF. Its shows the possibility to use this extract as photoprotective agent in pharmaceutical preparations.

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  • Common secondary plant compounds used as alternative photoprotectants include carotenoids, polyphenols, natural botanicals agents, phytochemicals, antioxidants, alkaloids and phenolic compounds.

    “Common secondary plant compounds used as alternative photoprotectants include carotenoids, polyphenols, natural botanicals agents, phytochemicals, antioxidants, alkaloids and phenolic compounds as illustrated in Fig .5 (Nunes et al. 2018;Fardiyah et al. 2020;Bendjedid et al. 2021).”

    From Skin protection from solar ultraviolet radiation using natural compounds: a review (2024) · cites this paper as Fardiyah et al. 2020

    The Introduction and §3.1 Phytochemical test (page numbers unavailable) describe plant extracts and their flavonoids, polyphenols, alkaloids, and phenolic compounds as relevant to photoprotection; §3.1 also describes some of these constituents as antioxidants. The paper does not identify carotenoids as photoprotectants, so it supports much, but not all, of the attributed list. (LLM, conf=0.86)

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Cited by

Sorted by citations

Authors
Fardiyah, Q., Ersam, T., Suyanta, Slamet, A., Suprapto, & Kurniawan, F.
Affiliations
Institut Teknologi Sepuluh Nopember (ID)
Corresponding author
Kurniawan, Fredy
ORCID
Venue
Arabian Journal of Chemistry
Publisher
Scientific Scholar
Published
2020-12
Volume
13
Issue
12
Pages
8888-8897
ISSN
1878-5352 (ISSN-L)
DOI
10.1016/j.arabjc.2020.10.015
OpenAlex
W3092750908
Cited by
51
References
0
Citations by year
2026: 3 · 2025: 6 · 2024: 11 · 2023: 14 · 2022: 12 · 2021: 5
FWCI
5.58
Type
journal article
Language
en
Open access
Licence
Locations
  • Arabian Journal of Chemistry (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Kementerian Riset Teknologi Dan Pendidikan Tinggi Republik Indonesia
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Health Sciences › Medicine › Complementary and alternative medicine › Andrographolide Research and Applications
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
Keywords
Andrographis paniculata, photoprotective agents, sun protection factor, plant extracts, flavonoids, phytochemical screening, UV fluorescence, Acanthaceae

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