The endocytic pathway in microglia during health, aging and Alzheimer’s disease
Solé-Domènech, Santiago, Cruz, Dana L., Capetillo-Zarate, Estibaliz, Maxfield, Frederick R.·2016·Ageing Research Reviews
Cited by (136)
Items 101–136 of 136
- Brain-targeting nanocages treat Alzheimer’s disease via regulating microglial polarization and remodeling microenvironmentHan Yang, Xiaowei Zhao, Min Liu, Xiaofang Li, Siyi Liu, Jingya Xiu, Dan Li, Jiulong Zhang, Xiuli Zhao · 2025 · International Journal of Pharmaceutics
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- Age-related nigral downregulation of the Parkinson’s risk factor FAM49B primes human microglia for inflammagingJacqueline Martin, Guan-Ju Lai, Christopher Y. Park, Colista West, Trevor Van Brunt, Samarah Ahmed, Saheed Lawal, Maya Dickson, Taylor Russo, Wendy Akmentin et al. · 2025 · npj Aging
- Genetic Architecture of Cognitive Resilience in Alzheimer’s Disease: Mechanisms, Pathways, and Therapeutic ImplicationsGabriel Burdman, Juliet Akkaoui, Natalia Colon, A. Garcia Perez, Madepalli Krishnappa Lakshmana · 2026 · Neurology International
- Targeting P2X7R Protects the Retina Against High-Altitude Hypoxia via NLRP3–Mediated Pyroptosis SuppressionKeke Ge, Yange Gu, Huan Xi, Siyuan John Liu, Yatao Wang, Lu Yang, Cong Han, Xingxing Zheng, Hao Wang, Siyu Huang et al. · 2026 · Molecular Neurobiology
- Dual orexin receptor antagonism with lemborexant enhances microglial clearance of β-amyloid in miceAshish Sharma, 瀬川英美子, Xiaoying Chen, Sohui Park, Shoutang Wang, Riley E. Irmen, Nicholas J. Constantino, Chanung Wang, Michael F. Kanan, Marco Colonna et al. · 2026 · Molecular Neurodegeneration
- Protein Interactions in the Last Steps of the Endosomal Degradative PathwayCelina Amaya Sanchez, María Isabel Colombo · 2017 · Journal of Cell Signaling
- A Network Pharmacology Study and Experimental Validation to Identify the Potential Mechanism of Heparan Sulfate on Alzheimer’s Disease-Related NeuroinflammationDong-Uk Kim, Bitna Kweon, Jinyoung Oh, Yebin Lim, Gyeongran Noh, Jihyun Yu, Hyang-Rin Kang, Tackmin Kwon, Kwang youll Lee, Gi‐Sang Bae · 2025 · Biomedicines
- Rhythmic patterns in microglial cells within the circadian pineal gland from male ratsCarlos Leandro Freites, Martin Avila, Juan B. Amiotti, Estela Maris Muñoz · 2025 · The Anatomical Record
- Cellular uptake of Alkyl-Modified Chitosan Nanoparticles by SIM-A9 and hCMEC/D3 cellsAnna Eleonora Caprifico, Peter J.S. Foot, Elena Polycarpou, Gianpiero Calabrese · 2024 · Research Square
- Macrophages in the reticuloendothelial system inhibit the propagation phase of mouse apolipoprotein A-II amyloidosisHiroki Miyahara, Jian Dai, Ying Li, Cui Xiaoran, Hibiki Takeuchi, Naomi Hachiya, Fuyuki Kametani, Masahide Yazaki, Masayuki Mori, Keiichi Higuchi · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Stress-relief function of migrasomal autophagosome formed by inhibition of autophagosome/lysosome fusionSeon Yong Lee, Sang-Hun Choi, Hee‐Sung Ahn, Young‐Gyu Ko, Kyunggon Kim, Sung Wook Chi, Hyunggee Kim · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Endocytosis in β-amyloid biology and Alzheimer’s diseaseBradlee L. Heckmann, Douglas R. Green · 2022 · Elsevier eBooks
- Real-Time Ratiometric pH Imaging of Macrophage Lysosomes Using the Novel pH-sensitive Probe ApHIDSantiago Solé‐Domènech, Pradeep Kumar Singh, J. David Warren, Frederick R. Maxfield · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Sobrecarga de cobre y enfermedad de Alzheimer, búsqueda de posibles blancos terapéuticosMarlene Zubillaga · 2023 · El Servicio de Difusión de la Creación Intelectual (National University of La Plata)
- Microglial activation and lysosomal dysfunction in hemorrhagic strokeChien-Hui Lee, Cheng‐Yoong Pang, Mei-Jen Wang, Wei-Fen Hu, Hsin‐Yi Huang, Sheng‐Tzung Tsai, Hock‐Kean Liew · 2025 · Tzu Chi Medical Journal
- Additional file 5 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizuresMacarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
- Additional file 2 of Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s diseaseMax E Stevenson, Varghese, Rency, Michaeline L. Hebron, Xiaoguang Liu, Nick Ratliff, Amelia Smith, Turner, R. Scott, Charbel Moussa · 2024 · Figshare
- Additional file 2 of DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s diseaseKylene P. Daily, Asmaa Badr, Mostafa M. Eltobgy, Shady Z. K. Estfanous, Owen D. Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew J. McNamara, Kaitlin Hamilton et al. · 2024 · Figshare
- Additional file 3 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizuresMacarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
- Additional file 1 of DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s diseaseKylene P. Daily, Asmaa Badr, Mostafa M. Eltobgy, Shady Z. K. Estfanous, Owen D. Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew J. McNamara, Kaitlin Hamilton et al. · 2024 · Figshare
- Additional file 1 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizuresMacarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
- Additional file 4 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizuresMacarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
- Additional file 2 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizuresMacarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
- Additional file 1 of Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s diseaseMax E Stevenson, Varghese, Rency, Michaeline L. Hebron, Xiaoguang Liu, Nick Ratliff, Amelia Smith, R. Scott Turner, Charbel Moussa · 2024 · Figshare
- Additional file 3 of DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s diseaseKylene P. Daily, Asmaa Badr, Mostafa M. Eltobgy, Shady Z. K. Estfanous, Owen D. Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew J. McNamara, Kaitlin Hamilton et al. · 2024 · Figshare
- Additional file 6 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizuresMacarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
- Decoding acute neuroinflammatory states from the 3D architecture of in vitro microgliaAnthoula Chatzimpinou, Johanna Huber, Xenia Podlipensky, James Lucas Cairns, Ayse S Erozan, Jian-Hua Chen, Valentina Loconte, Mark A. Le Gros, Carsten Hopf, Carolyn A. Larabell et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Protocol for the quantification of digestive exophagy in cell cultureLucy Funes, Frederick R. Maxfield, Santiago Solé‐Domènech · 2026 · STAR Protocols
- Etude de la protéine IRUFY3 sur le trafic endolysosomal des phagocytes professionnelsRémy Char · 2022 · theses.fr (ABES)
- Treadmill training induces sex-dependent changes in hippocampal epigenetic patterns and plaque-associated microglial morphology in aged TgF344 ratsAdam J. Schuller, Megan R. Hager, Aidan M. Briggs, Savannah M. Rocha, Omar A. Yanouri, Emma J. Smith, Stephanie E. Hall, Luke B. Montrose, Ronald B. Tjalkens · 2026 · Frontiers in Neuroscience
- LPI alleviates Alzheimer’s disease pathology via the GPR55 receptorWenjie Xu, J J Cao, Yibo Liu, Zimo Wei, Xu Zha, Shumin Xie, Xicheng Liu, Wang Wei, Chen Zhang · 2026 · Neuroscience · Retracted
- Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell LinesMuhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang · 2026 · Advanced NanoBiomed Research
- Ligand-free alkyl-modified chitosan nanoparticles are preferentially internalized by microglia and deliver curcumin to suppress cytokine releaseAnna Eleonora Caprifico, Marieta Vassileva, Rebecca M. C. Gabriele, Fiona Ducotterd, Duc Nguyen, Geoff Smith, Peter J.S. Foot, Elena Polycarpou, Gianpiero Calabrese · 2026 · Biomaterials Advances
- Genetic Risk Architecture of Late-Onset Alzheimer’s Disease: Mapping Single-Nucleotide Polymorphisms to Disease-Defining Molecular PathwaysClaudiu Matei, Nastaca Alina Palade, Ana-Maria Dobri, Dan Orga Dumitriu, Cosmin Mutu, Adriana Popescu, Alina Liliana Pintea, Diter Atasie · 2026 · Life
- BindingDB Entry 50022497: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.BindingDB · 2025 · UC San Diego