The endocytic pathway in microglia during health, aging and Alzheimer’s disease

Solé-Domènech, Santiago, Cruz, Dana L., Capetillo-Zarate, Estibaliz, Maxfield, Frederick R.·2016·Ageing Research Reviews

Cited by (136)

Items 101–136 of 136

  1. Brain-targeting nanocages treat Alzheimer’s disease via regulating microglial polarization and remodeling microenvironment
    Han Yang, Xiaowei Zhao, Min Liu, Xiaofang Li, Siyi Liu, Jingya Xiu, Dan Li, Jiulong Zhang, Xiuli Zhao · 2025 · International Journal of Pharmaceutics
  2. A Drug Screening Targeting Upregulation of Syk Gene Identifies Neochlorogenic Acid and L‐Arabinitol Capable of Inducing the M2 Phenotype of Microglia in Alzheimer's Disease
    Difei Hu, Xianling Li, Yeyin Li, Qiushuang Zhang, Yicong Dai, Xucong Teng, Hongwei Hou, Jinghong Li · 2025 · ChemBioChem
  3. Age-related nigral downregulation of the Parkinson’s risk factor FAM49B primes human microglia for inflammaging
    Jacqueline Martin, Guan-Ju Lai, Christopher Y. Park, Colista West, Trevor Van Brunt, Samarah Ahmed, Saheed Lawal, Maya Dickson, Taylor Russo, Wendy Akmentin et al. · 2025 · npj Aging
  4. Genetic Architecture of Cognitive Resilience in Alzheimer’s Disease: Mechanisms, Pathways, and Therapeutic Implications
    Gabriel Burdman, Juliet Akkaoui, Natalia Colon, A. Garcia Perez, Madepalli Krishnappa Lakshmana · 2026 · Neurology International
  5. Targeting P2X7R Protects the Retina Against High-Altitude Hypoxia via NLRP3–Mediated Pyroptosis Suppression
    Keke Ge, Yange Gu, Huan Xi, Siyuan John Liu, Yatao Wang, Lu Yang, Cong Han, Xingxing Zheng, Hao Wang, Siyu Huang et al. · 2026 · Molecular Neurobiology
  6. Dual orexin receptor antagonism with lemborexant enhances microglial clearance of β-amyloid in mice
    Ashish Sharma, 瀬川英美子, Xiaoying Chen, Sohui Park, Shoutang Wang, Riley E. Irmen, Nicholas J. Constantino, Chanung Wang, Michael F. Kanan, Marco Colonna et al. · 2026 · Molecular Neurodegeneration
  7. Protein Interactions in the Last Steps of the Endosomal Degradative Pathway
    Celina Amaya Sanchez, María Isabel Colombo · 2017 · Journal of Cell Signaling
  8. A Network Pharmacology Study and Experimental Validation to Identify the Potential Mechanism of Heparan Sulfate on Alzheimer’s Disease-Related Neuroinflammation
    Dong-Uk Kim, Bitna Kweon, Jinyoung Oh, Yebin Lim, Gyeongran Noh, Jihyun Yu, Hyang-Rin Kang, Tackmin Kwon, Kwang youll Lee, Gi‐Sang Bae · 2025 · Biomedicines
  9. Rhythmic patterns in microglial cells within the circadian pineal gland from male rats
    Carlos Leandro Freites, Martin Avila, Juan B. Amiotti, Estela Maris Muñoz · 2025 · The Anatomical Record
  10. Cellular uptake of Alkyl-Modified Chitosan Nanoparticles by SIM-A9 and hCMEC/D3 cells
    Anna Eleonora Caprifico, Peter J.S. Foot, Elena Polycarpou, Gianpiero Calabrese · 2024 · Research Square
  11. Macrophages in the reticuloendothelial system inhibit the propagation phase of mouse apolipoprotein A-II amyloidosis
    Hiroki Miyahara, Jian Dai, Ying Li, Cui Xiaoran, Hibiki Takeuchi, Naomi Hachiya, Fuyuki Kametani, Masahide Yazaki, Masayuki Mori, Keiichi Higuchi · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Stress-relief function of migrasomal autophagosome formed by inhibition of autophagosome/lysosome fusion
    Seon Yong Lee, Sang-Hun Choi, Hee‐Sung Ahn, Young‐Gyu Ko, Kyunggon Kim, Sung Wook Chi, Hyunggee Kim · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  13. Endocytosis in β-amyloid biology and Alzheimer’s disease
    Bradlee L. Heckmann, Douglas R. Green · 2022 · Elsevier eBooks
  14. Real-Time Ratiometric pH Imaging of Macrophage Lysosomes Using the Novel pH-sensitive Probe ApHID
    Santiago Solé‐Domènech, Pradeep Kumar Singh, J. David Warren, Frederick R. Maxfield · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  15. Sobrecarga de cobre y enfermedad de Alzheimer, búsqueda de posibles blancos terapéuticos
    Marlene Zubillaga · 2023 · El Servicio de Difusión de la Creación Intelectual (National University of La Plata)
  16. Microglial activation and lysosomal dysfunction in hemorrhagic stroke
    Chien-Hui Lee, Cheng‐Yoong Pang, Mei-Jen Wang, Wei-Fen Hu, Hsin‐Yi Huang, Sheng‐Tzung Tsai, Hock‐Kean Liew · 2025 · Tzu Chi Medical Journal
  17. Additional file 5 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures
    Macarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
  18. Additional file 2 of Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease
    Max E Stevenson, Varghese, Rency, Michaeline L. Hebron, Xiaoguang Liu, Nick Ratliff, Amelia Smith, Turner, R. Scott, Charbel Moussa · 2024 · Figshare
  19. Additional file 2 of DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease
    Kylene P. Daily, Asmaa Badr, Mostafa M. Eltobgy, Shady Z. K. Estfanous, Owen D. Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew J. McNamara, Kaitlin Hamilton et al. · 2024 · Figshare
  20. Additional file 3 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures
    Macarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
  21. Additional file 1 of DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease
    Kylene P. Daily, Asmaa Badr, Mostafa M. Eltobgy, Shady Z. K. Estfanous, Owen D. Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew J. McNamara, Kaitlin Hamilton et al. · 2024 · Figshare
  22. Additional file 1 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures
    Macarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
  23. Additional file 4 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures
    Macarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
  24. Additional file 2 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures
    Macarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
  25. Additional file 1 of Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease
    Max E Stevenson, Varghese, Rency, Michaeline L. Hebron, Xiaoguang Liu, Nick Ratliff, Amelia Smith, R. Scott Turner, Charbel Moussa · 2024 · Figshare
  26. Additional file 3 of DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease
    Kylene P. Daily, Asmaa Badr, Mostafa M. Eltobgy, Shady Z. K. Estfanous, Owen D. Whitham, Michelle H. Tan, Cierra Carafice, Kathrin Krause, Andrew J. McNamara, Kaitlin Hamilton et al. · 2024 · Figshare
  27. Additional file 6 of Microglia specific deletion of miR-155 in Alzheimer’s disease mouse models reduces amyloid-β pathology but causes hyperexcitability and seizures
    Macarena S. Aloi, Katherine E. Prater, Sánchez, Raymond E. A., Asad I. Beck, Jasmine L. Pathan, Stephanie Davidson, Angela M. Wilson, Keene, C. Dirk, Horacio O. de la Iglesia, Suman Jayadev et al. · 2024 · Figshare
  28. Decoding acute neuroinflammatory states from the 3D architecture of in vitro microglia
    Anthoula Chatzimpinou, Johanna Huber, Xenia Podlipensky, James Lucas Cairns, Ayse S Erozan, Jian-Hua Chen, Valentina Loconte, Mark A. Le Gros, Carsten Hopf, Carolyn A. Larabell et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  29. Protocol for the quantification of digestive exophagy in cell culture
    Lucy Funes, Frederick R. Maxfield, Santiago Solé‐Domènech · 2026 · STAR Protocols
  30. Etude de la protéine IRUFY3 sur le trafic endolysosomal des phagocytes professionnels
    Rémy Char · 2022 · theses.fr (ABES)
  31. Treadmill training induces sex-dependent changes in hippocampal epigenetic patterns and plaque-associated microglial morphology in aged TgF344 rats
    Adam J. Schuller, Megan R. Hager, Aidan M. Briggs, Savannah M. Rocha, Omar A. Yanouri, Emma J. Smith, Stephanie E. Hall, Luke B. Montrose, Ronald B. Tjalkens · 2026 · Frontiers in Neuroscience
  32. LPI alleviates Alzheimer’s disease pathology via the GPR55 receptor
    Wenjie Xu, J J Cao, Yibo Liu, Zimo Wei, Xu Zha, Shumin Xie, Xicheng Liu, Wang Wei, Chen Zhang · 2026 · Neuroscience · Retracted
  33. Biophysical Characterization and Proteomic Analysis of Small Extracellular Vesicles Derived From Different Neural Cell Lines
    Muhammad Waqas Salim, Wei Zhang, Lyndsey E. Collins‐Praino, Andrew Care, Yuling Wang · 2026 · Advanced NanoBiomed Research
  34. Ligand-free alkyl-modified chitosan nanoparticles are preferentially internalized by microglia and deliver curcumin to suppress cytokine release
    Anna Eleonora Caprifico, Marieta Vassileva, Rebecca M. C. Gabriele, Fiona Ducotterd, Duc Nguyen, Geoff Smith, Peter J.S. Foot, Elena Polycarpou, Gianpiero Calabrese · 2026 · Biomaterials Advances
  35. Genetic Risk Architecture of Late-Onset Alzheimer’s Disease: Mapping Single-Nucleotide Polymorphisms to Disease-Defining Molecular Pathways
    Claudiu Matei, Nastaca Alina Palade, Ana-Maria Dobri, Dan Orga Dumitriu, Cosmin Mutu, Adriana Popescu, Alina Liliana Pintea, Diter Atasie · 2026 · Life
  36. BindingDB Entry 50022497: Sustained microglial depletion with CSF1R inhibitor impairs parenchymal plaque development in an Alzheimer's disease model.
    BindingDB · 2025 · UC San Diego