NAD metabolism: Implications in aging and longevity

Cited by (267)

Items 101–200 of 267

1. Tryptophan Metabolism and COVID-19-Induced Skeletal Muscle Damage: Is ACE2 a Key Regulator?
   Hikari Takeshita, Koichi I. Yamamoto · 2022 · Frontiers in Nutrition
2. Activation of cardiac Nmnat/NAD+/SIR2 pathways mediates endurance exercise resistance to lipotoxic cardiomyopathy in aging Drosophila
   Deng‐tai Wen, Lan Zheng, Kai Lǚ, Wen-Qi Hou · 2021 · Journal of Experimental Biology
3. Palmitic Acid-Induced NAD+ Depletion is Associated with the Reduced Function of SIRT1 and Increased Expression of BACE1 in Hippocampal Neurons
   Manuel Flores‐León, Martha Pérez‐Domínguez, Rodrigo González‐Barrios, Clorinda Arias · 2019 · Neurochemical Research
4. Targeting cellular senescence as a new approach to chronic obstructive pulmonary disease therapy
   Peter John Barnes · 2020 · Current Opinion in Pharmacology
5. Nicotinamide riboside—A missing piece in the puzzle of exercise therapy for older adults?
   Carlo Custodero, Sunil Kumar Saini, Myung‐Jun Shin, Yun Kyung Jeon, Demetra D. Christou, Mary McGrae McDermott, Christiaan Leeuwenburgh, Stephen Douglas Anton, Robert T. Mankowski · 2020 · Experimental Gerontology
6. Deciphering the personalized functional redundancy hierarchy in the gut microbiome
   Yiqi Jiang, Lijia Che, Shuai Cheng Li · 2025 · Microbiome
7. Nicotinamide riboside supplementation ameliorated post-ovulatory oocyte quality decline
   Hui Li, Huan Wang, Jianmin Xu, Xinxin Zeng, Yingpu Sun, Qingling Yang · 2022 · Reproduction
8. Preclinical Characterization of Pharmacologic NAD + Boosting as a Promising Therapeutic Approach in Rheumatoid Arthritis
   C. Pérez‐Sánchez, Alejandro Escudero‐Contreras, Tomás Cerdó, Luz Marina Sánchez‐Mendoza, A. Llamas-Urbano, I. Arias de la Rosa, Miguel Pérez-Rodríguez, Laura Muñoz-Barrera, M. C. Ábalos‐Aguilera, Nuria Barbarroja et al. · 2023 · Arthritis & Rheumatology
9. Caffeine and NAD+ Improve Motor Neural Integrity of Dissociated Wobbler Cells In Vitro
   Mareike Zwilling, Carsten Theiß, Veronika Matschke · 2020 · Antioxidants
10. NAMPT promotes hepatitis B virus replication and liver cancer cell proliferation through the regulation of aerobic glycolysis
    Huijie Guo, Hongyu Li, Zi‐Hao Chen, Wenjing Zhou, Jia‐Jie Li, Jia‐Yi Zhang, Jing Wang, Xingyan Luo, Ting Zeng, Zhao Shi et al. · 2021 · Oncology Letters
11. Monounsaturated Fatty Acids in a High‐Fat Diet and Niacin Protect from White Fat Dysfunction in the Metabolic Syndrome
    Sergio Montserrat‐de la Paz, María C. Naranjo, María C. Millán-Linares, Sergio López, Rocı́o Abia, Erik A.L. Biessen, Francisco J.G. Muriana, Beatriz Bermúdez · 2019 · Molecular Nutrition & Food Research
12. Metabolomic profiles of induced pluripotent stem cells derived from patients with rheumatoid arthritis and osteoarthritis
    Juryun Kim, Sunyoung Christina Kang, Na Eun Yoon, Yena Kim, Jinhyeok Choi, Narae Park, Hyerin Jung, Byung Hwa Jung, Ji Hyeon Ju · 2019 · Stem Cell Research & Therapy
13. Deciphering the mechanism by which the yeastPhaffia rhodozymaresponds adaptively to environmental, nutritional, and genetic cues
    Luis B. Flores‐Cotera, Cipriano Chávez-Cabrera, Anahí Martínez‐Cárdenas, Sergio Sánchez, Oscar Ulises García-Flores · 2021 · Journal of Industrial Microbiology & Biotechnology
14. Novel Approach to Skin Anti-Aging: Boosting Pharmacological Effects of Exogenous Nicotinamide Adenine Dinucleotide (NAD+) by Synergistic Inhibition of CD38 Expression
    Seongsu Kang, Ji-Won Park, Zhihong Cheng, Sanghyun Ye, Seung‐Hyun Jun, Nae Gyu Kang · 2024 · Cells
15. Safety Evaluation for Restorin® NMN, a NAD+ Precursor
    J. Rick Turner, Albert Licollari, Emil Mihalcea, Aimin Tan · 2021 · Frontiers in Pharmacology
16. Low NAD+ Levels Are Associated With a Decline of Spermatogenesis in Transgenic ANDY and Aging Mice
    Mirella L. Meyer‐Ficca, Alexie E. Zwerdling, Corey A. Swanson, Abby G. Tucker, Sierra A. Lopez, Miles K. Wandersee, Gina M. Warner, Katie L. Thompson, Claudia C.S. Chini, Haolin Chen et al. · 2022 · Frontiers in Endocrinology
17. In Silico Insights into the SARS CoV-2 Main Protease Suggest NADH Endogenous Defences in the Control of the Pandemic Coronavirus Infection
    Annamaria Martorana, Carla Gentile, Antonino Lauria · 2020 · Viruses
18. Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner
    Xiangshu Cheng, Fang-Xiao Shi, Kun-Peng Zhao, Wang Lin, Xiao-Ying Li, Jun Zhang, Yao-Yao Bu, Rui Zhu, Xiao-Hong Li, Dong-Xiao Duan et al. · 2021 · Aging
19. The differential impact of three different NAD+ boosters on circulatory NAD and microbial metabolism in humans
    Stefan Christen, Karine Meisser Redeuil, Laurence Goulet, Maria Pilar Giner, Isabelle Breton, Riccardo Rota, Adrien Frézal, Atiye Nazari, Pieter Van den Abbeele, Jean‐Philippe Godin et al. · 2026 · Nature Metabolism
20. Metabolic signature of eyelid basal cell carcinoma
    Jiancheng Huang, Jamie Lea Schaefer, Yekai Wang, Lauren V. Gioia, Ying Pei, Xiaofei Shi, Shanawar Ali Waris, Chen Zhao, John Nguyen, Jianhai Du · 2020 · Experimental Eye Research
21. Efficient Assay and Marker Significance of NAD+ in Human Blood
    Natalia V. Balashova, Lev G. Zavileyskiy, Artem V. Artiukhov, Leonid A. Shaposhnikov, Sidorova Op, Vladimir I. Tishkov, Angela Tramonti, ANASTASIA A. POMETUN, Victoria I. Bunik · 2022 · Frontiers in Medicine
22. Ultraviolet B irradiation induces senescence of human corneal endothelial cells in vitro by DNA damage response and oxidative stress
    Guojian Jiang, Xin-Guo You, Ting‐Jun Fan · 2022 · Journal of Photochemistry and Photobiology B Biology
23. The interplay of NAD and hypoxic stress and its relevance for ageing
    Johannes Burtscher, Vanna Denti, Johanna Maria Gostner, Alexander KH Weiss, Barbara Strasser, Katharina Hüfner, Martin Burtscher, Giuseppe Paglia, Martin Kopp, Tobias Dünnwald · 2024 · Ageing Research Reviews
24. Tetrahydrobenzimidazole TMQ0153 targets OPA1 and restores drug sensitivity in AML via ROS-induced mitochondrial metabolic reprogramming
    Su Jung Park, Claudia Cerella, Jin Mo Kang, Jinyoung Byun, David Kum, Barbora Orlikova-Boyer, Anne Lorant, Michaël Schnekenburger, Ali Al‐Mourabit, Christo Christov et al. · 2025 · Journal of Experimental & Clinical Cancer Research
25. Advances of Glycometabolism Engineering in Chinese Hamster Ovary Cells
    Huan-Yu Zhang, Zhenlin Fan, Tianyun Wang · 2021 · Frontiers in Bioengineering and Biotechnology
26. Metabolic reprograming of cancer as a therapeutic target
    Tatsuhiko Furukawa, Sho Tabata, Kentaro Minami, Masatatsu Yamamoto, Kohichi Kawahara, Akihide Tanimoto · 2022 · Biochimica et Biophysica Acta (BBA) - General Subjects
27. Separation of reproductive decline from lifespan extension during methionine restriction
    Fangchao Wei, Shiyu Liu, Juan Liu, Yudong Sun, Annamarie E. Allen, Michael A. Reid, Jason W. Locasale · 2024 · Nature Aging
28. Altered Expression of Mitochondrial NAD+ Carriers Influences Yeast Chronological Lifespan by Modulating Cytosolic and Mitochondrial Metabolism
    Ivan Orlandi, Giulia Stamerra, Marina Vai · 2018 · Frontiers in Genetics
29. The interplay of senescence and MMPs in myocardial infarction: implications for cardiac aging and therapeutics
    Ashok Kumar Balaraman, Abdulmalik Saleh Alfawaz Altamimi, Marianesan Arockia Babu, Kavita Goyal, Gopalakrishnan Padmapriya, Pooja Bansal, Sumit Rajotiya, Mohit Kumar, Pranchal Rajput, Mohd Imran et al. · 2025 · Biogerontology
30. Senotherapy for chronic lung disease
    Peter John Barnes · 2025 · Pharmacological Reviews
31. NAD+ metabolism in peripheral neuropathic pain
    Yi Dai, Jiaqi Lin, Jinxuan Ren, Bin Zhu, Chengwei Wu, Lina Yu · 2022 · Neurochemistry International
32. The inflammatory response, a mixed blessing for muscle homeostasis and plasticity
    Zineb Bouredji, Anteneh Argaw, Jérôme Frenette · 2022 · Frontiers in Physiology
33. The immunosenescence clock: A new method for evaluating biological age and predicting mortality risk
    Shuyu Li, Ke Wang, Jingni Wu, Yongliang Zhu · 2024 · Ageing Research Reviews
34. A Plasma Proteomic Signature of Skeletal Muscle Mitochondrial Function
    Marta Zampino, Toshiko Tanaka, Ceereena Ubaida‐Mohien, Giovanna Fantoni, Julián Candia, Richard D. Semba, Luigi Ferrucci · 2020 · International Journal of Molecular Sciences
35. Senotherapy for lung diseases
    Peter John Barnes · 2023 · Advances in pharmacology
36. Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing
    Alvaro Martinez Guimera, Peter A. Clark, James Wordsworth, Sharath Anugula, Lene Juel Rasmussen, Daryl P. Shanley · 2022 · Experimental Gerontology
37. Nicotinamide mononucleotide (NMN) ameliorated Nonylphenol-induced learning and memory impairment in rats via the central 5-HT system and the NAD+/SIRT1/MAO-A pathway
    Huiying Huang, Jian Shi, Zhongyi Li, Yifeng Rang, Weiye Li, Xueman Xiao, Congying Chen, Chunhong Liu · 2023 · Food and Chemical Toxicology
38. Why is NMNAT Protective against Neuronal Cell Death and Axon Degeneration, but Inhibitory of Axon Regeneration?
    Bor Luen Tang · 2019 · Cells
39. The Effects of Graded Levels of Calorie Restriction: XIX. Impact of Graded Calorie Restriction on Protein Expression in the Liver
    Lu Wang, Davina Derous, Xiahe Huang, Sharon E. Mitchell, Alex Douglas, David Lusseau, Yingchun Wang, John Roger Speakman · 2023 · The Journals of Gerontology Series A
40. The 4 D’s of Pellagra and Progress
    Adrian C. Williams, Lisa J. Hill · 2020 · International Journal of Tryptophan Research
41. Modulation of Energy Sensing by Leucine Synergy with Natural Sirtuin Activators: Effects on Health Span
    Zemel, Michael B. · 2020 · Journal of Medicinal Food
42. Potential Therapeutic Effects of NAMPT-Mediated NAD Biosynthesis in Depression In Vivo
    Jue Wang, Runxuan Sun, Linhan Xia, Xinying Zhu, Qi Zhang, Yilu Ye · 2022 · Brain Sciences
43. Adipocyte-specific inactivation of NAMPT, a key NAD+ biosynthetic enzyme, causes a metabolically unhealthy lean phenotype in female mice during aging
    Nathan Qi, Michael P. Franczyk, Shintaro Yamaguchi, Daiki Kojima, Kaori Hayashi, Akiko Satoh, Noboru Ogiso, Takeshi Kanda, Yo Sasaki, Brian N. Finck et al. · 2024 · American Journal of Physiology-Endocrinology and Metabolism
44. Is the anti-aging effect of ACE2 due to its role in the renin-angiotensin system?—Findings from a comparison of the aging phenotypes of ACE2-deficient, Tsukuba hypertensive, and Mas-deficient mice—
    Hikari Takeshita, Koichi I. Yamamoto, Masaki Mogi, Satoko Nozato, Hiromi Rakugi · 2023 · Hypertension Research
45. Metabolic Engineering of Bacillus licheniformis for the Bioproduction of Nicotinamide Riboside from Nicotinamide and Glucose
    Menglin Zhou, Yi Li, Haotian Che, Yaqi Sun, Shan Wang, Yangyang Zhan, Dongbo Cai, Shouwen Chen · 2023 · ACS Sustainable Chemistry & Engineering
46. IDO‐1 Promotes Pulmonary Vascular Remodeling Via Kynurenine Pathway in Pulmonary Arterial Hypertension
    Zongye Cai, Ly Tu, Siyu Tian, Lin Deng, Yahong Fu, Carole Phan, Thierry P. P. van den Bosch, Karin Tran‐Lundmark, Bence Miklos Nagy, Horst Olschewski et al. · 2025 · Journal of the American Heart Association
47. A NADH Oxidase Nanozyme Restores Redox Homeostasis to Ameliorate Multi-Organ Aging and Ischemic Cardiomyopathy
    Yu Chen, Yunsong Liang, Jie Shen, Yueyan Wang, Baoni Qiu, Honghao Hou, Xiaozhong Qiu · 2025 · Research
48. Oncometabolic role of mitochondrial sirtuins in glioma patients
    Maria Fazal Ul Haq, Muhammad Zahid Hussain, Ishrat Mahjabeen, Zertashia Akram, Nadia Saeed, Rabia Shafique, Sumaira Fida Abbasi, Mahmood Akhtar Kayani · 2023 · PLoS ONE
49. Integration of non-targeted metabolomics with network pharmacology deciphers the anxiolytic mechanisms of Platycladi Semen extracts in CUMS mice
    Jiaqi Xie, Yihong Li, Yu‐Lu Liang, Hongqian Kui, Can Wang, Jianmei Huang · 2023 · Journal of Ethnopharmacology
50. Only time will tell: the interplay between circadian clock and metabolism
    Swetha Gopalakrishnan, Nisha N. Kannan · 2020 · Chronobiology International
51. Intracellular spatiotemporal metabolism in connection to target engagement
    Jingwei Zhang, Zhixia Qiu, Yongjie Jessica Zhang, Guangji Wang, Haiping Hao · 2023 · Advanced Drug Delivery Reviews
52. Biomarkers for toxicity detection
    Priyanka Devi, Preedhi Kapoor, Prasann Kumar · 2024 · Elsevier eBooks
53. Melatonin: a modulator in metabolic rewiring in T-cell malignancies
    Seema Rai, Gunja Roy, Younis Ahmad Hajam · 2024 · Frontiers in Oncology
54. Personalized quantitative models of NAD metabolism in hepatocellular carcinoma identify a subgroup with poor prognosis
    Adithya Chedere, Madhulika Mishra, Omkar Kulkarni, Shrisruti Sriraman, Nagasuma R Chandra · 2022 · Frontiers in Oncology
55. Higher Plasma Level of Nampt Presaging Memory Dysfunction in Chinese Type 2 Diabetes Patients with Mild Cognitive Impairment
    Xi Huang, Chenchen Wang, Sai Tian, Rong Huang, Dan Guo, Haoqiang Zhang, Jijing Shi, Shaohua Wang · 2019 · Journal of Alzheimer s Disease
56. Epigenetic Age Reversal by Cell-Extrinsic and Cell-Intrinsic Means
    Andrew R. Mendelsohn, James W. Larrick · 2019 · Rejuvenation Research
57. The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients
    Qiuyue Long, Shixu Song, Jianbo Xue, Wenyi Yu, Yaolin Zheng, Jiwei Li, Jing Wu, Xiaoyi Hu, Mingzheng Jiang, Hongli Ye et al. · 2025 · Frontiers in Immunology
58. Nicotinamide phosphoribosyltransferase inhibitor ameliorates mouse aging-induced cognitive impairment
    Min Zeng, Tao-Feng Wei, Cong Chen, Chen Shen, Tong‐Yao Gao, Xian Ming Xie, Ming Wu, Yun‐Bi Lu, Wei-Ping Zhang · 2021 · Journal of Cerebral Blood Flow & Metabolism
59. A Comparison of Gene Expression Profiles of Rat Tissues after Mild and Short-Term Calorie Restrictions
    Kenji Saito, Maiko Ito, Takuya Chiba, Huijuan Jia, Hisanori Kato · 2021 · Nutrients
60. Nicotinamide mononucleotide ameliorates acute lung injury by inducing mitonuclear protein imbalance and activating the UPR mt
    Shihan Du, Jia Shi, Tianyu Yu, Xinxin Hu, Simeng He, Yingya Cao, Zi-lei Xie, Shasha Liu, Yuting Li, Na Li et al. · 2022 · Experimental Biology and Medicine
61. Two-Photon-Excited FLIM of NAD(P)H and FAD—Metabolic Activity of Fibroblasts for the Diagnostics of Osteoimplant Survival
    Tatiana B. Lepekhina, Viktor Vladimirovich Nikolaev, Maxim E. Darvin, Hala Zuhayri, Mikhail S. Snegerev, Aleksandr S. Lozhkomoev, Сенькина Елена Ивановна, Andrey P. Kokhanenko, Kirill A. Lozovoy, Yury V. Kistenev · 2024 · International Journal of Molecular Sciences
62. Nicotinamide Riboside and CD38: Covalent Inhibition and Live-Cell Labeling
    Guoyun Kao, Xiaonan Zhang, Fariborz Nasertorabi, Benjamin B. Katz, Zeyang Li, Zhefu Dai, Zeyu Zhang, Lei Zhang, Stan G. Louie, Vadim Cherezov et al. · 2024 · JACS Au
63. Aptamers as Diagnostic and Therapeutic Agents for Aging and Age-Related Diseases
    Tae-In Park, Ah Hyun Yang, Bashistha Kumar Kanth, Seung Pil Pack · 2025 · Biosensors
64. Porcine placental extract increase the cellular NAD levels in human epidermal keratinocytes
    Takeshi Katayoshi, Nobuaki Yamaura, Takahisa Nakajo, Natsuko Kitajima, Kentaro Tsuji · 2022 · Scientific Reports
65. Untargeted Metabolomics Reveals the Protective Effect of a Traditional Chinese Herbal Decoction on Cisplatin‐Induced Acute Kidney Injury
    Yuyan Li, Xinhui Liu, Siqi Liu, Jiandong Lu, Jianping Chen, Guoliang Xiong, Shudong Yang, Shunmin Li · 2020 · Evidence-based Complementary and Alternative Medicine
66. Supplementation with NAD+ and its precursors: A rescue of female reproductive diseases
    Lan Li, Xin Zhou, Wene Liu, Zhen Chen, Xiaoqin Xiao, Guiming Deng · 2024 · Biochemistry and Biophysics Reports
67. NAD+ supplementation improves mitochondrial functions and normalizes glaucomatous trabecular meshwork features
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68. NAD+ glycohydrolases-CD38 as a therapeutic target in aging: physiological roles, molecular mechanisms, and future opportunities in anti-aging research
    Jing-Yu Sun, Zhifei Wang, Wenhui Xu, Jun Zhao · 2025 · Biochemical Pharmacology
69. Is NAD+ a key factor in ovarian aging and dysfunction? Insights and uncertainties from current research
    Valeria Cordone, Teresa Vergara, Stefano Falone, Carla Tatone, Giovanna Di Emidio · 2025 · Biology of Reproduction
70. Adipocyte NMNAT1 expression is essential for nuclear NAD+ biosynthesis but dispensable for regulating thermogenesis and whole-body energy metabolism
    Shintaro Yamaguchi, Daiki Kojima, Tooba Iqbal, Shotaro Kosugi, Michael P. Franczyk, Nathan Qi, Yo Sasaki, Keisuke Yaku, Kenji Kaneko, Kenichiro Kinouchi et al. · 2023 · Biochemical and Biophysical Research Communications
71. An overview of engineering microbial production of nicotinamide mononucleotide
    Baoxian Li, Xiangfeng Meng, Weifeng Liu · 2024 · Journal of Biotechnology
72. Mesenchymal stem cells and their derivatives as potential longevity-promoting tools
    Ekaterina A. Rudnitskaya, Alex Braiman, Marina Wolfson, Khachik K. Muradian, Vera A. Gorbunova, Gadi Turgeman, Vadim E. Fraifeld · 2025 · Biogerontology
73. NAMPT-mediated NAD + biosynthesis suppresses activation of hepatic stellate cells and protects against CCl 4 -induced liver fibrosis in mice
    Lin Xu, Chenyan Yang, Jie Ma, Xinge Zhang, Qingzhi Wang, Xiwen Xiong · 2021 · Human & Experimental Toxicology
74. Jian-Pi-Yi-Shen Formula Alleviates Chronic Kidney Disease in Two Rat Models by Modulating QPRT/NAD+/SIRT3/Mitochondrial Dynamics Pathway
    Xinhui Liu, Siqi Liu, Bing Zhang, Denggui Luo, Shiying Huang, Fochang Wang, Lin Zheng, Jiandong Lu, Jianping Chen, Shunmin Li · 2021 · Evidence-based Complementary and Alternative Medicine
75. Nicotinamide mononucleotide pretreatment improves long-term isoflurane anesthesia-induced cognitive impairment in mice
    Jiyan Xu, Xinlu Chen, Shuai Liu, Ziqi Wei, Minhui Xu, Linhao Jiang, Xue Han, Liangyu Peng, Xiaoping Gu, Tianjiao Xia · 2023 · Behavioural Brain Research
76. Loss of hepatic Nmnat1 has no impact on diet-induced fatty liver disease
    Tooba Iqbal, Allah Nawaz, Mariam Karim, Keisuke Yaku, Keisuke Hikosaka, Michihiro Matsumoto, Takashi Nakagawa · 2022 · Biochemical and Biophysical Research Communications
77. Role of mitochondria in nuclear DNA damage response
    Xipeng Zhao, Bin Chen, Lijun Wu, Guoping Zhao · 2022 · Genome Instability & Disease
78. Smoking cessation only partially reverses cardiac metabolic and structural remodeling in mice
    Jekaterina Aid, Ajime Tom Tanjeko, Jef Serré, Moritz Eggelbusch, Wendy Noort, Gerard M.J. de Wit, Michel van Weeghel, Marju Puurand, Kersti Tepp, Ghislaine Gayan‐Ramirez et al. · 2024 · Acta Physiologica
79. Targeting senescent cell clearance: An approach to delay aging and age-associated disorders
    Zhengqi Qiu, Jiali Jia, Haoman Zou, Ying Ao, Baohua Liu, Zimei Wang · 2021 · Translational Medicine of Aging
80. Characterization, Preclinical Efficacy and Toxicity Evaluations of Flavonoids Glycosides based Standardized Fenugreek Seed Extract (FEFLG)
    Prasad Arvind Thakurdesai, Pallavi Deshpande, Mukul P Pore · 2023 · Pharmacognosy Journal
81. Epigenome-wide association study of plasma lipids in West Africans: the RODAM study
    Eva L. van der Linden, Karlijn A. C. Meeks, Felix Patience Chilunga, Charles Frederick Hayfron-Benjamin, Silver Bahendeka, Kerstin Klipstein‐Grobusch, Andrea Venema, Bert‐Jan H. van den Born, Charles O Agyemang, Peter Henneman et al. · 2023 · EBioMedicine
82. Molecular pathways linking chronic psychological stress to accelerated aging: mechanisms and interventions
    Othman A. Alhazzaa, Hanin M. Abahussin, Majed A. Majrashi, Maryam S. Alotaibi, Mohammad Nasser Alkhrayef, Ziyad A. Alhamdan, Abdullah O. Alawad · 2026 · Frontiers in Aging
83. Discovery of a Potent Nicotinamide Phosphoribosyltransferase Activator for Improving Aging-associated Dysfunctions
    Sicheng Yang, Donghuan Sun, Ying Wu, Shuqiang Chen, Yuan Guo, Jian Li, Guoqiang Dong, Chunquan Sheng · 2024 · Journal of Medicinal Chemistry
84. Impact of Nuclear De Novo NAD + Synthesis via Histone Dynamics on DNA Repair during Cellular Senescence To Prevent Tumorigenesis
    Masae Ikura, Kanji Furuya, Tomonari Matsuda, Tsuyoshi Ikura · 2022 · Molecular and Cellular Biology
85. Remission of social behavior impairment by oral administration of a precursor of NAD in CD157, but not in CD38, knockout mice
    Maria Gerasimenko, Haruhiro Higashida · 2023 · Frontiers in Immunology
86. Nicotinamide phosphoribosyltransferase modulates PD-L1 in bladder cancer and enhances immunotherapeutic sensitivity
    Kuan‐Chou Chen, T.G. Murali Dhar, Chang-Rong Chen, Eugene Chang-Yu Chen, Chiung-Chi Peng · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
87. Early Diagnosis of Tumorigenesis via Ratiometric Carbon Dots with Deep-Red Emissive Fluorescence Based on NAD+ Dependence
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88. Small Molecule Regulators Targeting NAD+ Biosynthetic Enzymes
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89. Potentiating the anti-tumor response of tumor infiltrated T cells by NAD + supplementation
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90. Metabolic, epigenetic, and immune crosstalk in ovarian aging
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91. Need for NAD+: Focus on Striated Muscle Laminopathies
    Déborah Cardoso, Antoine Muchir · 2020 · Cells
92. Extracellular Nampt (eNampt/Visfatin/PBEF) directly and indirectly stimulates ACTH and CCL2 protein secretion from isolated rat corticotropes
    Piotr Celichowski, Karol Jopek, Marta Szyszka, Paulina Milecka, Marianna Tyczewska, Svetlana Sakhanova, Witold Szaflarski, Ludwik K. Malendowicz, Marcin Ruciński · 2021 · Advances in Clinical and Experimental Medicine
93. Nicotinamide Mononucleotide in the Context of Myocardiocyte Longevity
    Basheer Abdullah Marzoog · 2023 · Current Aging Science
94. Muscle mass, muscle strength and the renin-angiotensin system
    Hikari Takeshita, Koichi I. Yamamoto, Masaki Mogi, Hiromi Rakugi · 2024 · Clinical Science
95. Exploiting the therapeutic vulnerability of IDH-mutant gliomas with zotiraciclib
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96. The Influence of Mitochondrial Energy and 1C Metabolism on the Efficacy of Anticancer Drugs: Exploring Potential Mechanisms of Resistance
    Marika Frańczak, Isabel Toenshoff, Gerrit Jansen, Ryszard Tomasz Smolenski, Elisa Giovannetti, Godefridus J. Peters · 2022 · Current Medicinal Chemistry
97. Deletion of Nmnat1 in Skeletal Muscle Leads to the Reduction of NAD+ Levels but Has No Impact on Skeletal Muscle Morphology and Fiber Types
    Mariam Karim, Tooba Iqbal, Allah Nawaz, Keisuke Yaku, Takashi Nakagawa · 2023 · Journal of Nutritional Science and Vitaminology
98. Spatiotemporal transcriptomic profiling and modeling of mouse brain at single-cell resolution reveals cell proximity effects of aging and rejuvenation
    Eric Sun, Olivia Y. Zhou, Max Hauptschein, Nimrod Rappoport, Lucy Xu, Paloma Navarro Negredo, Ling A. Liu, Thomas A. Rando, James Zou, Anne Brunet · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
99. SkeletAge: Transcriptomics-based Aging Clock Identifies 26 New Targets in Skeletal Muscle Aging
    Muhammad Ali, Fei Li, Manpreet Singh Katari · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
100. High-throughput screening for ageing and age-related disease drug discovery: Advances and challenges
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