Learning ensemble classifiers for diabetic retinopathy assessment
Open accessAbstract
Diabetic retinopathy is one of the most common comorbidities of diabetes. Unfortunately, the recommended annual screening of the eye fundus of diabetic patients is too resource-consuming. Therefore, it is necessary to develop tools that may help doctors to determine the risk of each patient to attain this condition, so that patients with a low risk may be screened less frequently and the use of resources can be improved. This paper explores the use of two kinds of ensemble classifiers learned from data: fuzzy random forest and dominance-based rough set balanced rule ensemble. These classifiers use a small set of attributes which represent main risk factors to determine whether a patient is in risk of developing diabetic retinopathy. The levels of specificity and sensitivity obtained in the presented study are over 80%. This study is thus a first successful step towards the construction of a personalized decision support system that could help physicians in daily clinical practice.
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Saleh et al. reported that a fuzzy RF using retinal images for DR screening yielded an accuracy of 77.32%, sensitivity of 76.89%, and specificity of 77.43% for detecting the presence of DR.
“the best results yielded an accuracy of 77.32%, sensitivity of 76.89% and specificity of 77.43% for detecting the presence of DR”
From Artificial intelligence in diabetes management: Advancements, opportunities, and challenges (2023) · cites this paper as Saleh et al.109
Table 8 (Additional information; page not provided) assigns 77.32% accuracy, 76.89% sensitivity, and 77.43% specificity to DRSA, not the fuzzy random forest (FRF). It reports 80.29%, 80.67%, and 80.18%, respectively, for FRF. The Conclusions (page not provided) describe analysis of retinal photos as a later, still-in-progress stage rather than the input to these classifiers. (LLM, conf=0.92)
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Chalk, D., Pitt, M., Vaidya, B., & Stein, K. (2012) · Diabetes Care · doi:10.2337/dc11-2282 · Cited by 48 · see citing works
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Artificial intelligence in diabetes management: Advancements, opportunities, and challenges
Guan, Z., Li, H., Liu, R., Cai, C., Liu, Y., Li, J., Wang, X., Huang, S., Wu, L., Liu, D., et al. (2023) · Cell Reports Medicine · doi:10.1016/j.xcrm.2023.101213 · Cited by 287 · see citing works
“109 For CKD 39,110,111 and diabetic nephropathy 112,113 screening, studies utilized clinical data, metabolic biomarkers, genotyping data, and/or retinal images to achieve AUCs generally over 0.8.”
MethodInfluential
- Authors
- Saleh, E., Błaszczyński, J., Moreno, A., Valls, A., Romero-Aroca, P., de la Riva-Fernández, S., & Słowiński, R.
- Affiliations
- Universitat Rovira i Virgili (ES)
- Poznań University of Technology (PL)
- Venue
- Artificial Intelligence in Medicine
- Publisher
- Elsevier BV
- Published
- 2018-04
- Volume
- 85
- Pages
- 50-63
- ISSN
- 0933-3657 (ISSN-L)
- OpenAlex
- W2764302726
- Cited by
- 97
- References
- 1
- Citations by year
- 2026: 3 · 2025: 9 · 2024: 11 · 2023: 16 · 2022: 15 · 2021: 12 · 2020: 9 · 2019: 17 · 2018: 4 · 2017: 1
- FWCI
- 11.67
- Type
- journal article
- Language
- en
- Open access
- green
- hdl.handle.net
- Licence
- Locations
- Artificial Intelligence in Medicine (publishedVersion)
- PubMed (publishedVersion)
- Rovira & Virgili repository (submittedVersion, cc-by)
- Funders
- Spanish research projects (PI15/01150, PI12/01535)
- URV (2015PFR-URV-B2-60, 2016PFR-URV-B2-60)
- Martí-Franquès URV research fellowship programme (2016PMF-PIPF-24)
- Polish National Science Center (DEC-2013/11/B/ST6/00963)
- Topics
- Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Retinal Imaging and Analysis
- Physical Sciences › Computer Science › Computational Theory and Mathematics › Rough Sets and Fuzzy Logic
- Keywords
- diabetic retinopathy, risk prediction, ensemble classifiers, dominance-based rough set approach, clinical decision support, risk factors
- MeSH terms
- Clinical Decision-Making, Machine Learning, Decision Support Techniques, Decision Trees, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Diabetic Retinopathy, Humans, Predictive Value of Tests, Prognosis, Risk Factors, Time Factors, Reproducibility of Results, Fuzzy Logic, Risk Assessment, Decision Support Systems, Clinical, Electronic Health Records
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