The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Apo E4 and lipoprotein-associated phospholipase A2 synergistically increase cardiovascular risk
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Mutations in Lp-PLA2 are associated with increased risk for cardiovascular disease.
“and cardiovascular disease (90, 91).”
From Lipidome and proteome of astrocyte and microglia ApoE lipoprotein reveal differences based on cell type and ApoE isoform (2026) · cites this paper as [90]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Lynch, J. R., Tang, W., Wang, H., Vitek, M. P., Bennett, E. R., Sullivan, P. M., Warner, D. S., & Laskowitz, D. T. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306923200 · Cited by 394
Apolipoprotein-mediated pathways of lipid antigen presentation
Elzen, P. V. D., Garg, S., León, L., Brigl, M., Leadbetter, E. A., Gumperz, J. E., Dascher, C. C., Cheng, T.-Y., Sacks, F. M., Illarionov, P. A., et al. (2005) · Nature · doi:10.1038/nature04001 · Cited by 380
Flagged first, then by citations
Research works printed but not linked: 27
- Ross, 1999, Atherosclerosis-an inflammatory disease, N Engl J Med, 340, 115, 10.1056/NEJM199901143400207 · DOI · Paper page
- Eichner, 2002, Apolipoprotein E polymorphism and cardiovascular disease: a HuGE review, Am J Epidemiol, 155, 487, 10.1093/aje/155.6.487 · DOI · Paper page
- Gerdes, 2000, The apolipoprotein epsilon4 allele determines prognosis and the effect on prognosis of simvastatin in survivors of myocardial infarction: a substudy of the Scandinavian simvastatin survival study, Circulation, 101, 1366, 10.1161/01.CIR.101.12.1366 · DOI
- Anuurad, 2006, Protective effect of apolipoprotein E2 on coronary artery disease in African Americans is mediated through lipoprotein cholesterol, J Lipid Res, 47, 2475, 10.1194/jlr.M600288-JLR200 · DOI
- Howard, 1998, Association of apolipoprotein E phenotype with plasma lipoproteins in African-American and white young adults. The CARDIA study. Coronary artery risk development in young adults, Am J Epidemiol, 148, 859, 10.1093/oxfordjournals.aje.a009711 · DOI
- Mahley, 2000, Apolipoprotein E: far more than a lipid transport protein, Annu Rev Genomics Hum Genet, 1, 507, 10.1146/annurev.genom.1.1.507 · DOI · Paper page
- Eggertsen, 1993, Apolipoprotein E polymorphism in a healthy Swedish population: variation of allele frequency with age and relation to serum lipid concentrations, Clin Chem, 39, 2125, 10.1093/clinchem/39.10.2125 · DOI
- Pearson, 2003, Markers of inflammation and cardiovascular disease: application to clinical and public health practice: a statement for healthcare professionals from the centers for disease control and prevention and the American heart association, Circulation, 107, 499, 10.1161/01.CIR.0000052939.59093.45 · DOI · Paper page
- Latini, 2004, Prognostic significance of the long pentraxin PTX3 in acute myocardial infarction, Circulation, 110, 2349, 10.1161/01.CIR.0000145167.30987.2E · DOI
- Eiriksdottir, 2006, Apolipoprotein E genotype and statins affect CRP levels through independent and different mechanisms: AGES-Reykjavik Study, Atherosclerosis, 186, 222, 10.1016/j.atherosclerosis.2005.12.012 · DOI
- Grammer, 2011, Apolipoprotein E genotypes, circulating C-reactive protein and angiographic coronary artery disease: the Ludwigshafen risk and cardiovascular health study, Atherosclerosis, 215, 487, 10.1016/j.atherosclerosis.2011.01.005 · DOI
- Davidson, 2008, Consensus panel recommendation for incorporating lipoprotein-associated phospholipase A2 testing into cardiovascular disease risk assessment guidelines, Am J Cardiol, 101, 51F, 10.1016/j.amjcard.2008.04.019 · DOI
- Anuurad, 2010, Association of lipoprotein-associated phospholipase A2 with coronary artery disease in African-Americans and Caucasians, J Clin Endocrinol Metab, 95, 2376, 10.1210/jc.2009-2498 · DOI
- Hixson, 1990, Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI, J Lipid Res, 31, 545, 10.1016/S0022-2275(20)43176-1 · DOI · Paper page
- Macy, 1997, Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications, Clin Chem, 43, 52, 10.1093/clinchem/43.1.52 · DOI
- Clauss, 1957, Rapid physiological coagulation method in determination of fibrinogen, Acta Haematol, 17, 237, 10.1159/000205234 · DOI
- Saougos, 2007, Differential effect of hypolipidemic drugs on lipoprotein-associated phospholipase A2, Arterioscler Thromb Vasc Biol, 27, 2236, 10.1161/ATVBAHA.107.147280 · DOI
- Miller, 1990, Dyslipidemias with desirable plasma total cholesterol levels and angiographically demonstrated coronary artery disease, Am J Cardiol, 65, 1, 10.1016/0002-9149(90)90017-U · DOI
- Drabe, 2001, Genetic predisposition in patients undergoing cardiopulmonary bypass surgery is associated with an increase of inflammatory cytokines, Eur J Cardiothorac Surg, 20, 609, 10.1016/S1010-7940(01)00842-9 · DOI
- Mahley, 1996, Apolipoprotein E. Structure, function, and possible roles in Alzheimer's disease, Ann N Y Acad Sci, 777, 139, 10.1111/j.1749-6632.1996.tb34412.x · DOI
- Kuhlmann, 2010, Apolipoprotein E genotype and hepatitis C, HIV and herpes simplex disease risk: a literature review, Lipids Health Dis, 9, 8, 10.1186/1476-511X-9-8 · DOI
- Finch, 2007, Systemic inflammation, infection, ApoE alleles, and Alzheimer disease: a position paper, Curr Alzheimer Res, 4, 185, 10.2174/156720507780362254 · DOI
- Jofre-Monseny, 2008, Impact of apoE genotype on oxidative stress, inflammation and disease risk, Mol Nutr Food Res, 52, 131, 10.1002/mnfr.200700322 · DOI
- Ballantyne, 2004, Lipoprotein-associated phospholipase A2, high-sensitivity C-reactive protein, and risk for incident coronary heart disease in middle-aged men and women in the atherosclerosis risk in communities (ARIC) study, Circulation, 109, 837, 10.1161/01.CIR.0000116763.91992.F1 · DOI
- Epps, 2011, Lp-PLA- a novel risk factor for high-risk coronary and carotid artery disease, J Intern Med, 269, 94, 10.1111/j.1365-2796.2010.02297.x · DOI
- Enkhmaa, 2010, Association of Lp-PLA(2) activity with allele-specific Lp(a) levels in a bi-ethnic population, Atherosclerosis, 211, 526, 10.1016/j.atherosclerosis.2010.03.021 · DOI
- Murphy, 2011, ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice, J Clin Invest, 10.1172/JCI57559 · DOI · Paper page
Cited by
Sorted by citations
Strickland, M. R., Wang, Z., Golden, L. R., Wang, H., Lu, P., Ren, Y., Tabor, G. T., Zhao, N., Ulrich, J. D., Han, X., et al. (2026) · Journal of Lipid Research · doi:10.1016/j.jlr.2026.101000 · Cited by 8
Metadata
- Authors
- Gungor, Z., Anuurad, E., Enkhmaa, B., Zhang, W., Kim, K., & Berglund, L.
- Venue
- Atherosclerosis
- Publisher
- Elsevier BV
- Published
- 2012-07
- Volume
- 223
- Issue
- 1
- Pages
- 230-234
- ISSN
- 0021-9150
- PMC
- PMC3389284
- Cited by
- 27
- References
- 2
- Language
- en
- Funders
- National Heart, Lung, and Blood Institute (HL 62705)
- UC Davis Clinical and Translational Research Center (RR024146)
- UC Davis Clinical and Translational Science Center K12 Award (RR024144)
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
