Arteriovenous fistula maturation: physical exam versus flow study
Abstract
Purpose The purpose of this study was to determine the utility of routine duplex flow study 4 to 6 weeks after primary AVF creation and to compare physical exam against a duplex flow study in predicting fistula maturation. A surveillance algorithm was established to evaluate the naïve fistula after primary creation. Methods This was a single institution retrospective review of 155 veterans with primary autogenous AVF creation from 2016 to 2018. All patients received a duplex flow study evaluation after primary creation. A comparison was made between physical exam (PE) and flow study at 4 to 6 weeks post creation. Sensitivities and specificities of physical exam and duplex flow study were compared head-to-head in predicting unassisted fistula maturation. A mature AVF was defined as a fistula that could be repetitively cannulated and provided adequate flow for dialysis. Failure of maturation was defined as an AVF that was never usable for dialysis. An abnormal duplex included thrombosis, stenosis (> 50% on gray scale imaging), inadequate vein diameter ( Results There were 53 patients with radiocephalic (RC) fistulas, 41 patients with brachiocephalic (BC) fistulas, and 6 patients with brachiobasilic (BB) fistulas. Of patients with a confirmed abnormal duplex ultrasound, 53% had an abnormal PE (sensitivity 53%; PPV 96.3%, P Conclusion Abnormal duplex flow studies have a better sensitivity for detecting AVF failure or the need for reintervention compared to physical exam alone. An…
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Caputo et al. reported that when ultrasound Doppler was used as the gold standard, physical examination showed a sensitivity of 53% for detecting early functional loss of internal fistulas, while the specificity for identifying normal arteriovenous fistulas (AVFs) reached 98%.
“Caputo et al. (37) reported that when ultrasound Doppler was used as the gold standard, physical examination showed a sensitivity of 53% for detecting early functional loss of internal fistulas, while the specificity for identifying normal arteriovenous fistulas (AVFs) reached 98%.”
From Construction of nursing-sensitive quality indicators for hemodialysis vascular access: a Delphi study (2026) · cites this paper as [37]
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Zhang, Y., He, L., Tang, S., Gao, Y., Chen, H., Shi, M., & Chen, L. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1858484
- Authors
- Caputo, B. C., Leong, B., Sibona, A., Jhajj, S., Kohne, C., Gabel, J., Shih, W., Abou Zamzam, A., Bianchi, C., & Teruya, T.
- Affiliations
- Loma Linda University (US)
- Venue
- Annals of Vascular Surgery
- Publisher
- Elsevier BV
- Published
- 2021-11
- Volume
- 77
- Pages
- 16-24
- ISSN
- 0890-5096 (ISSN-L)
- OpenAlex
- W3194536385
- Cited by
- 14
- References
- 0
- Citations by year
- 2026: 3 · 2025: 1 · 2024: 2 · 2023: 5 · 2022: 3
- FWCI
- 3.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Licence
- Locations
- Annals of Vascular Surgery (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Emergency Medical Services › Central Venous Catheters and Hemodialysis
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Vascular Procedures and Complications
- Health Sciences › Medicine › Neurology › Vascular Malformations Diagnosis and Treatment
- Keywords
- arteriovenous fistula maturation, physical examination, hemodialysis vascular access, radiocephalic fistula, brachiocephalic fistula, brachiobasilic fistula, fistula failure, reintervention, veterans, sensitivity and specificity, surveillance algorithms, stenosis
- MeSH terms
- Aged, Algorithms, Arteriovenous Shunt, Surgical, Blood Flow Velocity, Graft Occlusion, Vascular, Renal Dialysis, Humans, Physical Examination, Predictive Value of Tests, Regional Blood Flow, Retrospective Studies, Time Factors, Vascular Patency, Reproducibility of Results, Treatment Outcome, Ultrasonography, Doppler, Duplex, Retreatment
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