FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity

Xiong, Xiao-Qing, Chen, Dan, Sun, Hai-Jian, Ding, Lei, Wang, Jue-Jin, Chen, Qi, Li, Yue-Hua, Zhou, Ye-Bo, Han, Ying, Zhang, Feng, Gao, Xing-Ya, Kang, Yu-Ming, Zhu, Guo-Qing·2015·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
DOI 10.1016/j.bbadis.2015.06.017

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  1. Sex specific effects of irisin on the skeleton
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  2. Association of irisin hormone with some physiological and inflammatory parameters of type 1 diabetic mellitus (TIDM) patiens in Thi-Qar province, Iraq
    Saad H. Al-Badry, Khalid G. Al-Fartosi · 2019 · Journal of Physics Conference Series
  3. Can irisin become a biomarker of physical activity, or another metabolic risk assessment parameter, in psychiatric care patients?
    Wojciech Łężak, Łukasz Mokros, Jakub Kaźmierski, Dominik Strzelecki, Hanna Jerczyńska, Edward Kowalczyk, Tadeusz Pietras · 2020 · Postępy Psychiatrii i Neurologii
  4. Research Progress of Irisin in Obesity and Related Metabolic Diseases
    怡宁 张 · 2023 · Advances in Clinical Medicine
  5. Exploring the role of irisin as a potential biomarker in adolescents and young adults with polycystic ovarian syndrome
    Sadaf Majeed, Hira Moin, Riffat Shafi, Sampana Fatima, Tatheer Zahra, Sarim Zafar · 2024 · Women s Health
  6. FNDC4 Prevents Aging-Related Cardiac Dysfunction
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  7. Irisina: ruolo nell’omeostasi del glucosio
    Annalisa Natalicchio, Nicola Marrano, Francesco Giorgino · 2018 · L Endocrinologo
  8. Editorial Retraction: A Review on the Role of Irisin in Insulin Resistance and Type 2 Diabetes Mellitus
    Hyun-Min Yoon, The EditorialBoard of Journal of Pharmacopuncture · 2020 · Journal of pharmacopuncture · Retracted
  9. Moderate-intensity exercise might be a competitive protocol to prevent obesity and obesity-related metabolic diseases
    Ryeo-Won Kwon, Seung‐Jea Lee, Tae-Wook Kim, Jeong‐Beom Lee · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  10. Plasma levels of irisin in children with idiopathic premature adrenarche
    Vanessa de Oliveira Furino, Fernanda de Oliveira Furino, Lucimar Retto da Silva de Avó, Débora Gusmão Melo, Carla Maria Ramos Germano · 2016 · International Journal of Advanced Nursing Studies
  11. Engineering Irisin for Understanding Its Benefits to Obesity
    Yousong Ding · 2016
  12. Lipid utilization in skeletal muscle cells is modulated in vitro and in vivo by specific miRNAs
    Francesco Chemello, Francesca Grespi, Alessandra Zulian, Pasqua Cancellara, Étienne Hébert-Chatelain, Paolo G. V. Martini, Camilla Bean, Enrico Alessio, Ruggero Ferrazza, Paolo Laveder et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  13. ASSOCIATION OF IRISIN WITH THE OXIDANT-ANTI OXIDANT PARAMETERS IN TYPE 2 DIABETIC PATIENTS ACCORDING TO AGE IN THI-QAR PROVINCE/ IRAQ
    Saad H. Al-Badry, Khalid G. Al-Fartosi · 2020 · International Journal of Research in Science and Technology
  14. Moringa (Moringa oleifera) leaves aqueous extract enhances fibronectin type III domain-containing protein 5 gene expression and serum irisin liberation in an obesity model
    Reem K Abdellah, Nadia M. El‐Beih, Fatma A. Morsy, Khaled G. Abdel-Wahhab, Enas A. El‐Hussieny · 2021 · Egyptian Pharmaceutical Journal
  15. The role of international retailing in the first and second global economy
    Nicholas Alexander, Anne Marie Doherty, Andrew Godley, Haiming Hang · 2011
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    Hong-Shi Li, Jiangying Kuang, Guijun Liu, Weijie Wu, Xianlun Yin, Hao-Dong Li, Lei Wang, Wenjiang Yan, Tao Qin, Wencheng Zhang et al. · 2021 · Research Square
  17. Expression Analysis of Irisin During Different Differentiation Stages of Skeletal Muscle Cells
    Yi Yan, Ding Cheng Yang, pei Wen, Yilei Li, Yufang Ge, Pei Ma, Jiahui Yuan, Pengxiang Zhang, Zhiwei Zhu, Xiaomao Luo et al. · 2021 · Research Square
  18. Physiological Effects of Irisin and its Research Progress
    卓 孙 · 2021 · Open Journal of Natural Science
  19. Egzersiz, İrisin ve Obezite
    Salih Öner, Yavuz Yasul · 2022 · Gaziantep Üniversitesi Spor Bilimleri Dergisi
  20. Role of Myokines and prospects for their role in Diabetes Mellitus Therapy
    Kharissova Nuriya, Mindubaуeva Farida, RK Sharma, Smirnova Liliya, Xeniya E. Mkhitaryan, Chergizova B., Yelena Salikhova, Y. Niyazova, Ryspayeva G., Evnevich A. et al. · 2024 · Research Journal of Pharmacy and Technology
  21. FNDC5-knock out induces skeletal muscle and liver metabolic disorders in mice, especially in mice with high fat diet
    Chao Xin, Yi Liu, Zheng Zhang, Jianan Wang, Hui Liu, Chengzhu Wang, Lijuan Zhang, Xiang Liao, Chengrong Zheng, Zhitao Jin et al. · 2025 · Research Square
  22. Irisin, bridging the gaps between exercise and cardiovascular health: A ray of hope
    Madiha Imran, Sadia Ahsin, Gule Naghma Saeed, Hira Ashraf · 2025 · Journal of Rehman Medical Institute
  23. Effects of low-intensity pulsed ultrasound on muscle mass and Fndc5 mRNA expression in aged male mice
    Yoshitsugu Kojima · 2025 · Biogerontology
  24. The effects of skeletal muscle conditioned medium on oxidative stress and morphometry of murine testicles cultured in vitro
    Fernanda Lima Alves, Maria Alice Felipe Oliveira, Solano Dantas Martins, Maria Joana Nogueira de Moura, Cibele dos Santos Borges, Leiz Maria Costa Véras, Vânia Marilande Ceccatto, Valdevane Rocha Araújo · 2025 · In Vitro Cellular & Developmental Biology - Animal
  25. Additional file 2 of Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3
    Xue, Chunling, Li, Xuechun, Ba, Li, Yamei Shen, Zhao Sun, Gu, Junjie, Yang, Ying, Han, Qin, Zhao, Robert Chunhua · 2022 · Figshare
  26. Additional file 2 of Association between irisin and metabolic parameters in nondiabetic, nonobese adults: a meta-analysis
    Yan Li, Zhenbin Xu · 2022 · Figshare
  27. Additional file 1 of Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3
    Xue, Chunling, Li, Xuechun, Ba, Li, Yamei Shen, Zhao Sun, Gu, Junjie, Yang, Ying, Han, Qin, Zhao, Robert Chunhua · 2022 · Figshare
  28. Additional file 6 of Association between irisin and metabolic parameters in nondiabetic, nonobese adults: a meta-analysis
    Yan Li, Xu, Zhenbin · 2022 · Figshare
  29. Additional file 1 of Association between irisin and metabolic parameters in nondiabetic, nonobese adults: a meta-analysis
    Yan Li, Xu, Zhenbin · 2022 · Figshare
  30. Additional file 5 of Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3
    Xue, Chunling, Li, Xuechun, Ba, Li, Yamei Shen, Zhao Sun, Gu, Junjie, Yang, Ying, Han, Qin, Zhao, Robert Chunhua · 2022 · Figshare
  31. Additional file 5 of Association between irisin and metabolic parameters in nondiabetic, nonobese adults: a meta-analysis
    Yan Li, Xu, Zhenbin · 2022 · Figshare
  32. Additional file 4 of Association between irisin and metabolic parameters in nondiabetic, nonobese adults: a meta-analysis
    Li, Yan, Xu, Zhenbin · 2022 · Figshare
  33. Additional file 4 of Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3
    Xue, Chunling, Li, Xuechun, Ba, Li, Yamei Shen, Zhao Sun, Gu, Junjie, Yang, Ying, Han, Qin, Zhao, Robert Chunhua · 2022 · Figshare
  34. Additional file 3 of Association between irisin and metabolic parameters in nondiabetic, nonobese adults: a meta-analysis
    Yan Li, Xu, Zhenbin · 2022 · Figshare
  35. Additional file 6 of Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3
    Xue, Chunling, Li, Xuechun, Ba, Li, Yamei Shen, Zhao Sun, Gu, Junjie, Yang, Ying, Han, Qin, Zhao, Robert Chunhua · 2022 · Figshare
  36. Additional file 3 of Irisin mediates beiging of adipose-derived mesenchymal stem cells through binding to TRPC3
    Xue, Chunling, Li, Xuechun, Ba, Li, Yamei Shen, Zhao Sun, Gu, Junjie, Yang, Ying, Han, Qin, Zhao, Robert Chunhua · 2022 · Figshare
  37. Impact d’une carence maternelle en vitamine D sur l’activité du tissu adipeux brun de la descendance
    Imene Bennour · 2022 · theses.fr (ABES)
  38. Altérations de la fonction motrice induites par une restriction sensorimotrice précoce chez le rat : implication du dialogue muscle-cerveau
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  39. The Effect of Saffron Extract Supplementation During Resistance Training on Hippocampal Doublecortin and Hepatic β ‐Hydroxybutyrate Levels in Rats With Type 2 Diabetes
    Vahid Valipour Dehnou, Amin Jalili Sarghaleh, Amin Karimi, Bahman Hasanvand, Hamed Alizadeh Pahlavani · 2026 · Journal of Diabetes Research
  40. Change in circulating irisin level and its association with lipid metabolism after exenatide treatment in patients with type 2 diabetes mellitus
    Yuting Gao, Xiaoyu Hong, Kun Yang, Yunyi Le, Rui Wei, Jin Yang, Tianpei Hong, Qing Tian · 2026 · Journal of Clinical & Translational Endocrinology
  41. Irisin in Cartilage Homeostasis: Molecular Mechanisms and Therapeutic Implications for Osteoarthritis
    Raffaella Rosy Vescio, Morena Francesca Fiordalisi, Luca Ambrosio, Daniele Fiorentino, Elisabetta de Rinaldis, Giuseppina Di Giacomo, Fabrizio Russo, Vincenzo Denaro, Gianluca Vadalà, Rocco Papalia · 2026 · Journal of Functional Morphology and Kinesiology
  42. Association of serum irisin concentration with abdominal adipose tissue and muscle area in a general population of Japanese men
    Naotsugu Akashi, Keiko Kondo, Aya Kadota, Sayuki Torii, Sayaka Kadowaki, Itsuko Miyazawa, Chiaki Sekine, Motoyuki Iemitsu, Takashi HISAMATSU, 晃子 原田 et al. · 2026 · Osteoporosis and Sarcopenia