The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
G protein coupled receptor structure and activation
Open accessAbstract
G protein coupled receptors (GPCRs) are remarkably versatile signaling molecules. The members of this large family of membrane proteins are activated by a spectrum of structurally diverse ligands, and have been shown to modulate the activity of different signaling pathways in a ligand specific manner. In this manuscript I will review what is known about the structure and mechanism of activation of GPCRs focusing primarily on two model systems, rhodopsin and the beta(2) adrenoceptor.
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Citations
Cites
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Trong, I. L., Teller, D. C., Okada, T., Stenkamp, R. E., et al. (2000) · Science · doi:10.1126/science.289.5480.739 · Cited by 5,637
Fredriksson, R., Lagerström, M. C., Lundin, L.-G., & Schiöth, H. B. (2003) · Molecular Pharmacology · doi:10.1124/mol.63.6.1256 · Cited by 2,941
The Retinal Conformation and its Environment in Rhodopsin in Light of a New 2.2 Å Crystal Structure
Okada, T., Sugihara, M., Bondar, A.-N., Elstner, M., Entel, P., & Buss, V. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.07.044 · Cited by 1,049
Cited by
The clinical toxicology of caffeine: A review and case study
Willson, C. (2018) · Toxicology Reports · doi:10.1016/j.toxrep.2018.11.002 · Cited by 289
Activation and Inhibition of Adenylyl Cyclase Isoforms by Forskolin Analogs
Pinto, C., Papa, D., Hübner, M., Mou, T.-C., Lushington, G. H., & Seifert, R. (2008) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.107.131904 · Cited by 82
Chen, C.-H., Di, Y.-Q., Shen, Q.-Y., Wang, J.-X., & Zhao, X.-F. (2019) · Journal of Biological Chemistry · doi:10.1074/jbc.ra119.008484 · Cited by 16
Angiotensin 1–7 Modulates the Dynamics and Activation of the Proto‐Oncogene Mas Receptor
Yasar, E., Dogru, S., Eroglu, E., & Yaras, N. (2026) · Journal of Molecular Recognition · doi:10.1002/jmr.70031 · Cited by 1
Metadata
- Authors
- Kobilka, B. K.
- Venue
- Biochimica et Biophysica Acta (BBA) - Biomembranes
- Publisher
- Elsevier BV
- Published
- 2007-04
- Volume
- 1768
- Issue
- 4
- Pages
- 794-807
- ISSN
- 0005-2736 (ISSN-L)
- OpenAlex
- W1978310995
- Cited by
- 623
- References
- 3
- FWCI
- 7.61
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.