Nobiletin, a Citrus Flavonoid, Improves Cognitive Impairment and Reduces Soluble Aβ Levels in a Triple Transgenic Mouse Model of Alzheimer’s Disease (3XTg-AD)
Nakajima, Akira, Aoyama, Yuki, Shin, Eun-Joo, Nam, Yunsung, Kim, Hyoung-Chun, Nagai, Taku, Yokosuka, Akihito, Mimaki, Yoshihiro +3 more·2015·Behavioural Brain Research
Cited by (138)
Items 101–138 of 138
- Neuroprotective role of nobiletin against amyloid-β (Aβ) aggregation in Parkinson and Alzheimer disease as neurodegenerative diseases of brainVahid Alivirdiloo, Mobasher Hajiabbasi, Morad Kohandel Gargari, Homa Kohandel Gargari, Farhood Ghazi, Mahya Mohammadi, Fatemeh Rahimi, Ahmad Mobed, A. Mehra · 2024 · Medicinal Chemistry Research
- Time matters: circadian genetics and the molecular logic of human health and diseaseTia Tyrsett Kuo, Jiarui Wang, Steve A. Kay · 2026 · Nature Reviews Genetics
- Aging of Citri Reticulatae pericarpium: Flavonoid metabolite dynamics, fungal community succession, and functional analysis of key transformation strainsZhanming Tang, Yanyan Miao, Huimin Lu, Chao Chen, Shiming Li, Wensheng Zhang · 2025 · Food Research International
- QTL mapping of polymethoxyflavone (PMF) accumulation in citrusYomi Matsumoto, Takehiro Kubo, Yuri Itami, Md. Zaherul Islam, Satoshi Watanabe, Nobuhiro Kotoda · 2022 · Tree Genetics & Genomes
- Exploring role of citrus fruits in comorbid neurodegenerative disorders associated with psoriasisAdil Ali, Ankit Chaudhary, Alok Nath Sharma, Nazia Siddiqui, Anurag, Vipan Kumar Parihar · 2024 · Metabolic Brain Disease
- Nobiletin suppresses the development of experimental autoimmune encephalomyelitis mediated by modulation of T helper 17 cell differentiationAkiko Nakamoto, Yuwa Hirabayashi, Chieri Anzaki, Mariko Nakamoto, Emi Shuto, Tohru Sakai · 2021 · Journal of Clinical Biochemistry and Nutrition
- Components of Goutengsan in Rat Plasma by Microdialysis Sampling and Its Protection on Aβ1–42‐Induced PC12 Cells InjuryHoucai Huang, Chunfei Wang, Junfei Gu, Juan Chen, Xuefeng Hou, Rongling Zhong, Zhi Xia, Di Zhao, Nan Yang, Jing Wang et al. · 2017 · Evidence-based Complementary and Alternative Medicine
- The Search for Citrus Components with Neuroprotective and Anti-dementia Effects in the Mouse BrainSatoshi Okuyama, Atsushi Sawamoto, Mitsunari Nakajima, Yoshiko Furukawa · 2021 · YAKUGAKU ZASSHI
- The role of microbiota modulation in preventing Alzheimer’s disease- a reviewAnna Strzępa, Marian Szczepanik · 2025 · Pharmacological Reports
- Novel nano-crystalline solid dispersion of nobiletin with improved dissolution behavior and oral absorptionAtsushi Uchida, Kayo Yuminoki, Naofumi Hashimoto, Hideyuki Sato, Yoshiki Seto, Satomi Onoue · 2022 · Journal of Drug Delivery Science and Technology
- Nöroprotektif Etkili Bir Flavonoid: NobiletinGül Fatma Yarım, Metin Çenesiz, Murat Yarım, Filiz Kazak · 2017 · Harran Üniversitesi Veteriner Fakültesi Dergisi
- Flavonoids and Diarylheptanoids: Neuroprotective Activities of PhytochemicalsKathyani Parasram · 2017 · International Journal of Pharmacology Phytochemistry and Ethnomedicine
- Potential role of nobiletin in Alzheimer’s diseaseHuilin Fang, Lingling Zhang, Hui Zhao · 2023 · Journal of Food Bioactives
- Natural Bioactive Compounds as Adjuvant Therapy for Hepatitis C InfectionMoema de Souza Santana, Rute Lopes, Isabela H. Peron, Carla Rios da Cruz, Ana Maria Minarelli Gaspar, Paulo Inácio da Costa · 2020 · Current Nutrition & Food Science
- Vitamin C and Citrus peels—a treasure chest for healthy lifeHiba Habeeb, John Ernest Thoppil · 2024 · Elsevier eBooks
- Exploring the Neuroprotective Promise of Functional Fruit PhytochemicalsTebalelo Lehlaleroa, Chika Ifeanyi Chukwuma, Muriel C. Mari, Samson Sitheni Mashele, Claudia Ntsapi · 2026 · Journal of Food Biochemistry
- Phytochemical Composition and Mechanistic Pharmacology of the Citrus Genus: Focus on Organic ConstituentsHimangi Vig, Ankita Wal, Preeti Sharma, Jyotsana Dwivedi, Bhagawati Saxena, Nardev Singh, Akash Ved, Prema Suseela, Amin Gasmi · 2026 · Current Organic Chemistry
- Metabolic Engineering for Biotechnological Production of Bioactive Methylated Flavonoids and Stilbenes: Progress and PerspectivesSabina Shrestha, Tae‐Jin Oh · 2026 · Applied Biochemistry and Biotechnology
- Phytometabolites as therapeutics for Alzheimer’s disease: mechanistic insights into neuroprotection and amyloid clearancePriyanka Sharma, Aatif Subhan, Samriti Saklania, Suresh Thareja · 2026 · Phytochemistry Reviews
- FONKSİYONEL GIDA BİLEŞENLERİNİN BİLİŞSEL FONKSİYONLAR ÜZERİNE MOLEKÜLER ETKİ MEKANİZMALARIZeynep B. Güzel‐Seydim, Sinem Keles, Gülçin Şatır · 2024 · JOURNAL OF BIOTECHNOLOGY AND STRATEGIC HEALTH RESEARCH
- Recent Advances on Therapeutic Mechanism and Potential of Flavonoids and Carotenoids: A Focus on Alzheimer’s and Parkinson’s DiseaseBalaji Govindaswamy, Kevin Nickson Stephen, S. Keerthana, Sarath Perumal, M. Thirumurugan · 2025 · Springer eBooks
- Neuroprotection by Dietary and Citrus FlavonoidsSam Hwang, Ping Shih, Gow‐Chin Yen · 2017 · Functional foods & nutraceuticals series
- Flavonoids in Transgenic Alzheimer's Disease Mouse ModelsA. M. Sabogal-Guáqueta, E. Osorio, G. P. Cardona-Gómez · 2017
- Alteration of cholesterol homeostasis in the Huntington's disease brainFabian Kreilaus · 2015 · Research Online (University of Wollongong)
- Effects of Nobiletin in Animal Models of Cognitive ImpairmentAkira Nakajima, Yasushi Ohizumi, Kiyofumi Yamada · 2017
- Нобилетин: направленное воздействие на циркадные ритмы для обеспечения нормальной биоэнергетики и здорового старенияЕ. Милейковская, С.-Х. Ёо, У. Доухан, Ж. Чен · 2020 · Biochemistry (Moscow)
- THERAPEUTIC POTENTIAL OF VARIOUS PHYTOCHEMICALS IN THE MANAGEMENT OF ALZHEIMER’S DISEASE2022 · International Journal of Biology Pharmacy and Allied Sciences
- The Therapeutic Role of Flavonoids for Alzheimer's DiseaseJinchi Wei, Zichun Liu, Chiming Wei · 2023 · Clinical Neurology and Neuroscience
- Nobiletin as a Neuroprotective Agent: Therapeutic Potential and Formulation Strategies for Alzheimer’s and Related DisordersAshish Parihar · 2025 · Journal of Drug Delivery and Therapeutics
- Nobiletin Ameliorates Aβ 1–42 ‐Induced Cognitive Disorder and Mitochondrial Dysfunction via Targeting the Key Circadian Regulator Bmal1Huajing Gao, Qinglin Qu, Ning Wang, Xue Jun Gao, Peihua Li, Yanquan Mou, Xiangrui Kong, Yannan Chen, Dapeng Li, Xintong Tan · 2025 · Food Safety and Health
- Isopropylated phenyl phosphate, an organophosphorus flame retardant, induces depressive- and anxiety-like behaviors in miceYuina Inoue, Shun Chiba, Hayato Maeda, Akira Nakajima · 2026 · Toxicology and Applied Pharmacology
- Recent Alzheimer’s Research Targets Amyloid-β with Novel Phytochemicals and Pharmacological Strategies for TherapyShikha Sharma, Utkarsh Sharma, Neeraj Kumar Sethiya, Lakshit Singh · 2026 · Current Aging Science
- Effets de l’administration de tétrahydrobioptérine en condition physiologique et pathologique : De la neurobiologie au comportementHortense Fanet · 2018 · theses.fr (ABES)
- Antioxidant Effect of Citrus FlavonoidsChongde Sun, Yue Wang, Jianbo Xiao, Jinping Cao, Cui Sun, Dengliang Wang · 2026 · Advanced topics in science and technology in China
- Nobiletin ameliorates diabetic nephropathy by modulating TP53-associated PANoptosis: an experimental studyBiwei Zhang, Yi Liu, Leilei Ma, Yingjie Zhao, Yiming Dong, Zhengqi Zhou, Chunyu Tian, Dongjun Wang, Dingjie Xu, 喇孝瑾 et al. · 2026 · Frontiers in Nutrition
- Nobiletin-rich Citrus depressa Peel extract enhances detoxification-related responses and reduces benzo[a]pyrene bioaccumulation in ratsMeiling Li, Yu-Hsuan Chiang, Shang-Ming Huang, Hsien‐Tsung Yao, Kuo‐Chiang Hsu · 2026 · Food Chemistry
- Nobiletin as a Geroprotective Flavonoid: Mechanisms of Action, Therapeutic Potential, and Challenges of BioavailabilitySzymon Sip, Anna Gościniak, Niklas Hoede, Min Hein Htike, Hnin Yuzana Khin, Wei-Wei Lai, Hein Htet Naing, Agnieszka Szopa, Judyta Cielecka‐Piontek · 2026 · Antioxidants
- Valorization of Citrus Waste for Recovery of Nutritional and Bioactive Compounds: A Comprehensive ReviewMonika, Rhythm Kalsi, J. Bhasin, Rafeeya Shams, K. Dash · 2026 · Future Postharvest and Food