Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells

Oxidative stress: oxidants and antioxidants

Sies, H. (1997) · Experimental Physiology · doi:10.1113/expphysiol.1997.sp004024 · Cited by 4,577

Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases

Johnson, G. L., & Lapadat, R. (2002) · Science · doi:10.1126/science.1072682 · Cited by 4,295

An Nrf2/Small Maf Heterodimer Mediates the Induction of Phase II Detoxifying Enzyme Genes through Antioxidant Response Elements

Itoh, K., Chiba, T., Takahashi, S., Ishii, T., Igarashi, K., Katoh, Y., Oyake, T., Hayashi, N., Satoh, K., Hatayama, I., et al. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.6943 · Cited by 3,999

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D., & Yamamoto, M. (1999) · Genes & Development · doi:10.1101/gad.13.1.76 · Cited by 3,634

The Relative Antioxidant Activities of Plant-Derived Polyphenolic Flavonoids

Rice-Evans, C. A., Miller, N. J., Bolwell, P., Bramley, P. M., & Pridham, J. B. (1995) · Free Radical Research · doi:10.3109/10715769509145649 · Cited by 2,160

Heme oxygenase: Function, multiplicity, regulatory mechanisms, and clinical applications

Maines, M. D. (1988) · The FASEB Journal · doi:10.1096/fasebj.2.10.3290025 · Cited by 1,707

Glutathione and glutathione-dependent enzymes represent a co-ordinately regulated defence against oxidative stress

Hayes, J. D., & McLellan, L. I. (1999) · Free Radical Research · doi:10.1080/10715769900300851 · Cited by 1,528

The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

Rushmore, T. H., Morton, M. R., & Pickett, C. B. (1991) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)99004-6 · Cited by 1,464

Nrf2, a Cap'n'Collar Transcription Factor, Regulates Induction of the Heme Oxygenase-1 Gene

Alam, J., Stewart, D. P., Touchard, C. L., Boinapally, S., Choi, A. M. K., & Cook, J. L. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.37.26071 · Cited by 1,284

Regulatory Mechanisms Controlling Gene Expression Mediated by the Antioxidant Response Element

Nguyen, T., Sherratt, P. J., & Pickett, C. B. (2003) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.43.100901.140229 · Cited by 1,232

Anti-Inflammatory Effects of Ribes diacanthum Pall Mediated via Regulation of Nrf2/HO-1 and NF-κB Signaling Pathways in LPS-Stimulated RAW 264.7 Macrophages and a TPA-Induced Dermatitis Animal Model

Kim, N. Y., Cheong, S. H., Lee, K. J., Sok, D., & Kim, M. R. (2020) · Antioxidants · doi:10.3390/antiox9070622 · Cited by 18

Role of long non-coding RNAs on the regulation of Nrf2 in chronic diseases

Jayasuriya, R., & Ramkumar, K. M. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.119025 · Cited by 18

Effects of star anise (Illicium verum Hook.f) oil on the nuclear factor E2–related factor 2 signaling pathway of chickens during subclinical Escherichia coli challenge

Ding, X. L., Yang, C., Yang, Z., Ren, X., & Wang, P. (2020) · Poultry Science · doi:10.1016/j.psj.2019.10.004 · Cited by 18

Drugs and Acute Porphyrias: Reasons for a Hazardous Relationship

Roveri, G., Nascimbeni, F., Rocchi, E., & Ventura, P. (2014) · Postgraduate Medicine · doi:10.3810/pgm.2014.11.2839 · Cited by 18

Artichoke compound cynarin differentially affects the survival, growth, and stress response of normal, immortalized, and cancerous human cells

Gezer, C., Yücecan, S., & Rattan, S. I. S. (2015) · TURKISH JOURNAL OF BIOLOGY · doi:10.3906/biy-1407-67 · Cited by 18

Plasma membrane redox enzymes: new therapeutic targets for neurodegenerative diseases

Hyun, D. (2019) · Archives of Pharmacal Research · doi:10.1007/s12272-019-01147-8 · Cited by 19

Low Cost Process for Phenolic Compounds Extraction from Cabernet Sauvignon Grapes (Vitis vinifera L. cv. Cabernet Sauvignon). Optimization by Response Surface Methodology

Hajj, Y. E., Louka, N., Nguyen, C., & Maroun, R. G. (2012) · Food and Nutrition Sciences · doi:10.4236/fns.2012.31014 · Cited by 17

S-Allylcysteine Protects Against Excitotoxic Damage in Rat Cortical Slices Via Reduction of Oxidative Damage, Activation of Nrf2/ARE Binding, and BDNF Preservation

Reyes-Soto, C. Y., Rangel‐López, E., Galván‐Arzate, S., Colín-González, A. L., Silva‐Palacios, A., Zazueta, C., Pedraza‐Chaverrí, J., Carreto, R. J. R., Chavarría, A., Túnez, I., et al. (2020) · Neurotoxicity Research · doi:10.1007/s12640-020-00260-7 · Cited by 17

Frequency modulated translocational oscillations of Nrf2, a transcription factor functioning like a wireless sensor

Xue, M., Momiji, H., Rabbani, N., Bretschneider, T., Rand, D. A. J., & Thornalley, P. J. (2015) · Biochemical Society Transactions · doi:10.1042/bst20150060 · Cited by 17

Similarities and Distinctions in the Effects of Metformin and Carbon Monoxide in Immunometabolism.

Park, J., Joe, Y., Ryter, S. W., Surh, Y., & Chung, H. (2019) · PubMed · doi:10.14348/molcells.2019.0016 · Cited by 16

CHP1002, a novel andrographolide derivative, inhibits pro-inflammatory inducible nitric oxide synthase and cyclooxygenase-2 expressions in RAW264.7 macrophages via up-regulation of heme oxygenase-1 expression

Zhang, B., Yan, L.-D., Zhou, P., Dong, Z., Feng, S., Liu, K., & Gong, Z. (2012) · International Immunopharmacology · doi:10.1016/j.intimp.2012.12.003 · Cited by 16

Upregulation of haeme oxygenase-1 by zinc in HCT-116 cells

Smith, A. F., & Loo, G. T. (2012) · Free Radical Research · doi:10.3109/10715762.2012.690872 · Cited by 16

Pyrus ussuriensis Maxim 70% ethanol eluted fraction ameliorates inflammation and oxidative stress in LPS ‐induced inflammation in vitro and in vivo

Peng, F., Ren, X., Du, B., & Yang, Y. (2022) · Food Science & Nutrition · doi:10.1002/fsn3.3077 · Cited by 14

Phytochemicals as Prototypes for Pharmaceutical Leads Towards Drug Development Against Diabetic Cardiomyopathy

Ojha, S. K., Kurdi, A., Sadek, B. S., Kaleem, M., Cai, L., Kamal, M. A., & Rajesh, M. (2016) · Current Pharmaceutical Design · doi:10.2174/1381612822666160322145255 · Cited by 15

Differential Activation of Glioprotective Intracellular Signaling Pathways in Primary Optic Nerve Head Astrocytes after Treatment with Different Classes of Antioxidants

Ghosh, A. K., Rao, V. R., Wisniewski, V. J., Zigrossi, A., Floss, J. C., Koulen, P., Stubbs, E. B., & Kaja, S. (2020) · Antioxidants · doi:10.3390/antiox9040324 · Cited by 15

Resveratrol Prevents GLUT3 Up-Regulation Induced by Middle Cerebral Artery Occlusion

Aguilar, G. F. G., Alquisiras-Burgos, I., Franco‐Pérez, J., Pineda-Ramírez, N., Ortíz-Plata, A., Torres, I., Pedraza‐Chaverrí, J., & Aguilera, P. (2020) · Brain Sciences · doi:10.3390/brainsci10090651 · Cited by 15

Induction of Heme Oxygenase-1 by Plant Extract KIOM-79 via Akt Pathway and NF-E2 Related Factor 2 in Pancreatic β-Cells

Kang, K. A., Kim, J. S., Zhang, R., Piao, M. J., Ko, D. O., Wang, Z. H., Maeng, Y. H., Eun, S. Y., & Hyun, J. W. (2008) · Journal of Toxicology and Environmental Health · doi:10.1080/15287390802271624 · Cited by 15

Foodomics-Based Approaches Shed Light on the Potential Protective Effects of Polyphenols in Inflammatory Bowel Disease

Pratelli, G., Tamburini, B., Carlisi, D., Blasio, A. D., D’Anneo, A., Emanuele, S., Notaro, A., Affranchi, F., Giuliano, M., Seidita, A., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914619 · Cited by 14

Dysregulation of MAP kinase signaling pathways including p38MAPK, SAPK/JNK, and ERK1/2 in cultured rat cerebellar astrocytes exposed to diphenylarsinic acid

Negishi, T., Matsumoto, M., Kobayashi, Y., Kojima, M., Sakaguchi, F., Takahata, K., Kanehira, T., Arakaki, R., Aoyama, Y., Yoshida, H., et al. (2017) · Toxicological Sciences · doi:10.1093/toxsci/kfx012 · Cited by 14

Do Naturally Occurring Antioxidants Protect Against Neurodegeneration of the Dopaminergic System? A Systematic Revision in Animal Models of Parkinson's Disease

Costas‐Ferreira, C., & Faro, L. R. F. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210421092725 · Cited by 14

Microarray analysis of the inflammatory and immune responses in head kidney turbot leucocytes treated with resveratrol

Domínguez, B., Pardo, B. G., Noia, M., Millán, A., Gómez‐Tato, A., Martı́nez, P., Leiro, J. M., & Lamas, J. (2013) · International Immunopharmacology · doi:10.1016/j.intimp.2013.01.024 · Cited by 13

Palbinone from Paeonia suffruticosa Protects Hepatic Cells via Up‐regulation of Heme Oxygenase‐1

Ha, D. T., Tran, P., Oh, J., Bae, K., Thuan, N. D., & Na, M. (2013) · Phytotherapy Research · doi:10.1002/ptr.4993 · Cited by 13

Polyphenols in Regulation of Redox Signaling and Inflammation During Cardiovascular Diseases

Niu, L., He, X., Wang, Q., Fu, M., Xu, F., Xue, Y., Wang, Z., & An, X.-J. (2015) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-014-0492-5 · Cited by 13

Targeting the Nrf2/HO-1 aixs: A therapeutic strategy against regulated cell death in Alzheimer’s disease

Wang, Z., Feng, W., Li, X., Yun, X., Wu, S., Du, L., & Wang, H. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103035 · Cited by 15

Regulation of redox signalling and autophagy during cardiovascular diseases-role of resveratrol.

Fu, D. (2015) · PubMed · Cited by 12

AMP-activated protein kinase as a promoting factor, but complement and thrombin as limiting factors for acquisition of cytoprotection: implications for induction of accommodation

Iwasaki, K., Miwa, Y., Haneda, M., Kuzuya, T., Ogawa, H. K., Ōnishi, A., & Kobayashi, T. (2013) · Transplant International · doi:10.1111/tri.12186 · Cited by 12

Spontaneous mutagenesis in Csb m/m Ogg1 −/− mice is attenuated by dietary resveratrol

Fußer, M., Nesse, G., Khobta, A., Xia, N., Li, H., Klungland, A., & Epe, B. (2010) · Carcinogenesis · doi:10.1093/carcin/bgq196 · Cited by 12

Can resveratrol supplementation affect biomarkers of inflammation and oxidative stress? An umbrella meta-analysis

Shoura, S. M. S., Naghsh, N., Moslemi, E., Kavyani, Z., Moridpour, A. H., Musazadeh, V., & Dehghan, P. (2022) · Journal of Functional Foods · doi:10.1016/j.jff.2022.105360 · Cited by 11

Establishment of Nrf2-deficient HaCaT and immortalized primary human foreskin keratinocytes and characterization of their responses to ROS-induced cytotoxicity

Choi, M., Park, M., Lee, S., Lee, J. W., Choi, W. J., & Lee, C.-H. (2019) · Toxicology in Vitro · doi:10.1016/j.tiv.2019.104602 · Cited by 11

Butylated hydroxyanisole stimulates heme oxygenase-1 gene expression and inhibits neointima formation in rat arteries

LIU, X., Azam, M. A., Peyton, K. J., Ensenat, D., Keswani, A. N., WANG, H., & Durante, W. (2007) · Cardiovascular Research · doi:10.1016/j.cardiores.2007.01.017 · Cited by 11

A comparative assessment of the cytotoxicity and nitric oxide reducing ability of resveratrol, pterostilbene and piceatannol in transformed and normal mouse macrophages

Achy-Brou, C. A. A., & Billack, B. (2016) · Drug and Chemical Toxicology · doi:10.3109/01480545.2016.1169542 · Cited by 11

WITHDRAWN: Heme oxygenase-1 mediates the anti-inflammatory effect of propyl gallate in LPS-stimulated macrophages

Jeon, W.-K., & Kim, B.-C. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.07.056 · Cited by 11

NPC Natural Product Communications

Khana, S. I., Hester, J. P., Tekwania, B. L., Midiwob, J. O., Muhammada, I., Jaina, S. K., Jacoba, M. R., Walkera, L. A., Rahmana, A. A., & Samoylenkoa, V. (2011) · Cited by 11

Dependence of Retinal Pigment Epithelium Integrity on the NRF2–Heme Oxygenase-1 Axis

Jiang, Y., Duan, L., Pi, J., Le, Y.-Z., & Fong, G. (2022) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.63.9.30 · Cited by 10

The Heme Oxygenase/Biliverdin Reductase System as Effector of the Neuroprotective Outcomes of Herb-Based Nutritional Supplements

Mhillaj, E., Cuomo, V., Trabace, L., & Mancuso, C. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.01298 · Cited by 10

Brassicaphenanthrene A from Brassica�rapa protects HT22 neuronal cells through the regulation of Nrf2‑mediated heme oxygenase‑1 expression

Lee, H., Ko, W., Chowdhury, A., Li, B., Kim, S., Oh, H., Kim, Y., Woo, E., Baek, N., & Lee, D. (2019) · Molecular Medicine Reports · doi:10.3892/mmr.2019.10824 · Cited by 10

Glyoxalase 1 Inducer, trans-Resveratrol and Hesperetin–Dietary Supplement with Multi-Modal Health Benefits

Xue, M., Rabbani, N., & Thornalley, P. J. (2025) · Antioxidants · doi:10.3390/antiox14080956 · Cited by 9

Nanomedicine: A New Frontier in Alzheimer’s Disease Drug Targeting

Pathak, K., Ahmad, M. Z., Saikia, R., Pathak, M. P., Sahariah, J. J., Kalita, P., Das, A., Islam, M. A., Pramanik, P., Tayeng, D., et al. (2024) · Central Nervous System Agents in Medicinal Chemistry · doi:10.2174/0118715249281331240325042642 · Cited by 11

Pleiotropic Effects of Resveratrol on Aging-Related Cardiovascular Diseases—What Can We Learn from Research in Dogs?

Grzeczka, A., Graczyk, S., & Kordowitzki, P. (2024) · Cells · doi:10.3390/cells13201732 · Cited by 9

Grape Seed Procyanidins Attenuates Cisplatin-induced Human Embryonic Renal Cell Cytotoxicity by Modulating Heme Oxygenase-1 in Vitro

Han, H., Wang, H., Du, Y., & Gao, L. (2019) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-019-00890-5 · Cited by 9

Sirtuin 1 Agonist Minimizes Injury and Improves the Immune Response Following Traumatic Shock

Luciano, J. A., Kautza, B. C., Darwiche, S. S., Martinez, S., Stratimirovic, S., Waltz, P. K., Sperry, J. L., Rosengart, M., Shiva, S., & Zuckerbraun, B. S. (2015) · Shock · doi:10.1097/shk.0000000000000412 · Cited by 9

Aging: silencing the PKA and AkT/PKB signaling pathways alters the antioxidant capacity of resveratrol

Franco, F. N., Cardoso, L. D. C., Silva, B. N. M., de Araújo, G. R., & Chaves, M. M. (2023) · Biogerontology · doi:10.1007/s10522-023-10046-x · Cited by 8

Mitochondria and Parkinson's Disease

Simon, D. K., Chu, C. T., & Swerdlow, R. H. (2011) · Parkinson s Disease · doi:10.4061/2011/261791 · Cited by 8

Atherosclerosis

Roberts, C. K. (2014) · CRC Press eBooks · doi:10.1201/b16783-5 · Cited by 8

Pharmacological Modulations of Nrf2 and Therapeutic Implications in Aneurysmal Subarachnoid Hemorrhage

Qia, Z., Zhang, J., & Mo, J. (2023) · Molecules · doi:10.3390/molecules28041747 · Cited by 7

Benzo(e)pyrene Inhibits Endothelium-Dependent NO-Mediated Dilation of Retinal Arterioles via Superoxide Production and Endoplasmic Reticulum Stress

Kamiya, T., Nagaoka, T., Omae, T., Ono, S., Otani, S., & Yoshida, A. (2017) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.17-21925 · Cited by 7

(E)-N-(2-(3, 5-Dimethoxystyryl) phenyl) furan-2-carboxamide (BK3C231) induces cytoprotection in CCD18-Co human colon fibroblast cells through Nrf2/ARE pathway activation

Tan, H. H., Thomas, N. F., Inayat‐Hussain, S. H., & Chan, K. M. (2021) · Scientific Reports · doi:10.1038/s41598-021-83163-7 · Cited by 7

SARS-CoV-2-induced host metabolic reprogram (HMR): nutritional interventions for global management of COVID-19 and post-acute sequelae of COVID-19 (PASC)

Naidu, A. S., Shahidi, F., Wang, C., Sato, K., Wirakartakusumah, A., Aworh, O. C., & Clemens, R. (2022) · Journal of Food Bioactives · doi:10.31665/jfb.2022.18306 · Cited by 7

Nicotine Exposure Augments Renal Toxicity of 5-azacytidine Through p66shc: Prevention by Resveratrol

Arany, I., HALL, S., Faisal, A., & Dixit, M. P. (2017) · Anticancer Research · doi:10.21873/anticanres.11793 · Cited by 7

Decoding the role of transcriptomic clocks in the human prefrontal cortex

Martínez‐Magaña, J. J., Vlot, A. H. C., Sullivan, K. A., Jacobson, D. A., Krystal, J. H., Girgenti, M. J., Núñez-Ríos, D. L., Nagamatsu, S. T., Andrade-Brito, D., Merlet, J., et al. (2026) · iScience · doi:10.1016/j.isci.2026.116439 · Cited by 6

Structurally Diverse Phenylpropanamides from Cannabis Fructus and Their Potential Neuroprotective Effects

Zhang, S., Huang, J., Fu, J., Yu, Q., Zhang, X., Yao, X., Zhu, L., & Liu, H. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c00242 · Cited by 7

Pharmacologic Means of Extending Lifespan

Lamming, D. W. (2012) · Journal of Clinical & Experimental Pathology · doi:10.4172/2161-0681.s4-002 · Cited by 6

Increasing resveratrol bioavailability: A therapeutic challenge focusing on the mitochondria

Sandhir, R., Singhal, N. K., & Garg, P. (2021) · Elsevier eBooks · doi:10.1016/b978-0-323-85666-9.00004-8 · Cited by 6

Skin Aging and Microbiology

Baumann, L., Weisberg, E. M., & Percival, S. L. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-327-1_4 · Cited by 6

Mechanisms of Action of Phenolic Phytochemicals in Diabetes Management

Hoda, M., Hemaiswarya, S., & Doble, M. (2019) · Springer eBooks · doi:10.1007/978-981-13-8997-9_4 · Cited by 6

Plant Polyphenols as Dietary Modulators of Brain Functions

Vauzour, D., Kerr, J. S., & Czank, C. (2013) · Polyphenols in Human Health and Disease · doi:10.1016/b978-0-12-398456-2.00027-x · Cited by 6

Resveratrol Analogs Ameliorate Mitochondrial Impairment and Insulin Resistance in a Streptozotocin-Induced In Vitro Model of Alzheimer’s Disease

Paszternák, A., Varga, K., Gyöngyössy, R., Tarnóczi, K., Sikur, N., Szökő, É., & Tábi, T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262110787 · Cited by 5

Chemopreventive effects of standardized papaya leaf fraction on oxidatively stressed human liver cells

Tan, S.-A. S. W., Goya, L., Ramanathan, S., Sulaiman, S. F., Alam, M. S., & Navaratnam, V. (2014) · Food Research International · doi:10.1016/j.foodres.2014.06.040 · Cited by 5

Exploring the Potential of Resveratrol as Feed Supplement in Aquaculture – A Review

Malarvizhi, K., Kalaiselvan, P., & Ranjan, A. (2024) · Annals of Animal Science · doi:10.2478/aoas-2024-0074 · Cited by 4

An anticancer/cytotoxic activity of resveratrol is not hampered by its ability to induce the expression of the antioxidant/cytoprotective heme oxygenase-1 in RAW264.7 cells

Kil, J. S., Son, Y. H., Cheong, Y.-K., Kim, N., Jeong, H. J., Kang, S. D., Chung, H., & Pae, H. (2011) · Biomedicine & Preventive Nutrition · doi:10.1016/j.bionut.2011.02.006 · Cited by 4

Regulation of Inflammation, Redox, and Glucocorticoid Signaling by Dietary Polyphenols

Biswas, S. K., & Rahman, I. (2008) · Oxidative stress and disease · doi:10.1201/9780849381492.ch6 · Cited by 4

Beneficial effects of phenolic compounds from fruit and vegetables in neurodegenerative diseases

Singh, M., & Ramassamy, C. (2008) · Elsevier eBooks · doi:10.1533/9781845694289.2.145 · Cited by 5

Molecular Mechanisms Involved in the Neuroprotective Action of Phytochemicals

Sunkaria, A., Yadav, A., Sharma, S. K., & Sandhir, R. (2017) · Wiley eBooks · doi:10.1002/9781119155195.ch27 · Cited by 4

Natural Products that Generate Carbon Monoxide

Cruz, L. K. D. L., & Wang, B. (2022) · Wiley eBooks · doi:10.1002/9781119783435.ch17 · Cited by 4

Dietary phytochemicals targeting Nf-KB signalling pathways: Potential cancer chemoprevention strategy

Aliyu, M., Bonomi, Z. M., & Idoko, A. S. (2023) · Dutse Journal of Pure and Applied Sciences · doi:10.4314/dujopas.v9i2a.18 · Cited by 3

Nanomedicine Based Drug Targeting in Alzheimer’s Disease: High Impact of Small Carter

Ahmad, M. Z., Akhter, S., Rahman, Z., Ahmad, J., Ahmad, I., & Ahmad, F. J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-803959-5.50016-7 · Cited by 3

Intracellular Signaling Molecules as Targets of Selected Dietary Chemopreventive Agents

Kundu, J. K., Na, H., & Surh, Y. (2008) · Oxidative stress and disease · doi:10.1201/9780849381492.ch1 · Cited by 3

How Do Structurally Distinct Compounds Exert Functionally Identical Effects in Combating Obesity?

Deng, Z., Liu, R.-X., Li, A., Guo, J., & Zeng, Q.-P. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00069 · Cited by 2

Identification and Biological Characterization of a Novel NRF2 Activator Molecule Released From the Membranes of Heat‐Treated Bifidobacterium breve NCC 2950

Foata, F., Duboux, S., Herzig, S., Sizzano, F., Thévenet, J., Guy, P. A., Rezzi, S., Métairon, S., Bourqui, B., Montoliu, I., et al. (2025) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202400770 · Cited by 2

Advances in Asian pear research: active ingredients, health benefits, processing trends and challenges

Chen, L., Wang, H., Lu, J., Cao, J., & Jiang, W. (2025) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2025.2508852 · Cited by 2

The Diet–Multiple Sclerosis Connection: Oxidative Stress and Emerging Mechanisms

Bucciero, C., Croce, A., Castellano, G., Bèguinot, F., Formisano, P., Portella, G., Ulianich, L., Fiory, F., & Malfitano, A. M. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-05748-5 · Cited by 2

Network Pharmacology and Transcriptome Analysis Reveal Potential Cardiometabolic Targets of Polygonum cuspidatum

Oh, J., Choo, J., Yang, G. R., Chu, H., & An, W. G. (2026) · Biomedicines · doi:10.3390/biomedicines14030516 · Cited by 2

Introduction

Obulesu, M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-816412-9.00001-x · Cited by 3

ROS/Redox Regulation with Dietary Phytochemicals and Role in Anticancer Activity

Bansal, M. P. (2023) · Springer eBooks · doi:10.1007/978-981-99-7342-2_3 · Cited by 2

How do drug discovery scientists address the unmet need of long COVID syndrome therapeutics and what more can be done?

Pagliano, P., Salzano, F., D’Amore, C., Spera, A. M., Conti, V., Folliero, V., Franci, G., & Ascione, T. (2025) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2025.2534056 · Cited by 2

Acute and chronic exercise effects on NrF2 and antioxidants in the muscle and brain tissue of Sprague Dawley rats

Vervaecke, L. S. (2017) · NC Digital Online Collection of Knowledge and Scholarship (The University of North Carolina at Greensboro) · Cited by 3

Anti-inflammatory effect of grape seed may involve the induction of heme oxygenase-1 and suppression of nuclear factor-κB activation

Sung, J., Kim, Y., Choi, Y. M., Ham, H., Jeong, H., & Lee, J. (2011) · Food Science and Biotechnology · doi:10.1007/s10068-011-0236-x · Cited by 2

Free Radical–Mediated Damage to Brain in Alzheimer’s Disease: Role of Acrolein and Preclinical Promise of Antioxidant Polyphenols

Ramassamy, C., Arseneault, M., & Nam, D. T. (2010) · Humana Press eBooks · doi:10.1007/978-1-60761-602-3_21 · Cited by 2

Neuroprotective Mechanisms of Dietary Phytochemicals

Davinelli, S., Scapagnini, G., Koverech, G., Luca, M., Calandra, C., & Calabrese, V. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801816-3.00019-4 · Cited by 2

Prospective stem cell lines as in vitro neurodegenerative disease models for natural product research

Mansor, N. I., Azmi, N., Ling, K., Rosli, R., Hassan, Z., & Nordin, N. (2019) · Neuroscience Research Notes · doi:10.31117/neuroscirn.v2i1.25 · Cited by 2

Biphasic Effects of Resveratrol on Adipogenesis: Low Doses of Resveratrol Promote Adipogenesis via Induction of CD36

(2015) · Journal of Nutrition and Health · doi:10.13188/2469-4185.1000005 · Cited by 2

Resveratrol: Biochemistry and Functions

Das, S., Vasanthi, H. R., & Das, D. K. (2009) · doi:10.1002/9780470531792.ch14 · Cited by 2

Resveratrol and Its Nitric Oxide–Donor Hybrid as an Emerging Therapy for Oxidative-Stress-Driven Priapism in Sickle Cell Disease

Splendore, C. O., de Oliveira, M. G., Costa, F. F., & Silva, F. H. (2025) · Antioxidants · doi:10.3390/antiox14101213 · Cited by 1

Phytochemicals and brain health: cognitive enhancement and neuroprotection

Itrat, N., Saroosh, R., Raza, H., & Ali, A. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-26494-8.00015-x · Cited by 1

Adenosine A2A Receptors Mediate Resveratrol-Induced Nrf2 Activation and Cytoprotection Against Oxidative Stress in HeLa Cells

Fructuoso, C., Sánchez-Melgar, A., Albasanz, J. L., & Lopez, M. M. (2026) · Pharmaceuticals · doi:10.3390/ph19060853 · Cited by 1

Clinical Trials of Ischemic Conditioning

Katsnelson, M. J., & Koch, S. (2012) · Springer eBooks · doi:10.1007/978-1-4419-9695-4_30 · Cited by 1

Modulation of the Nrf2 Signaling Pathway by Chemopreventive Dietary Phytoconstituents

Darvesh, A. S., & Bishayee, A. (2012) · Springer eBooks · doi:10.1007/978-94-007-2923-0_20 · Cited by 1

Hepatoprotective Effects of Chitosan‐Phloroglucinol Conjugate in Cultured Hepatocyte

Woo, J.-Y., Yang, H., Ahn, G., Kim, K., & Je, J.-Y. (2016) · Journal of Food Biochemistry · doi:10.1111/jfbc.12265 · Cited by 2

Free Radicals and Islet Function

Acharya, J. D., & Ghaskadbi, S. (2014) · Springer eBooks · doi:10.1007/978-3-642-30018-9_154 · Cited by 1

Magnoliae Cortex extract protects PC12 cells from cytotoxicity induced by hydrogen peroxide or 6-hydroxydopamine through enzyme induction

Nishiyama, T., Masuda, Y., Izawa, T., Ohnuma, T., Ogura, K., & Hiratsuka, A. (2019) · Fundamental Toxicological Sciences · doi:10.2131/fts.6.107 · Cited by 1

Mesenchymal stem cells proliferation augmentation by preconditioning with resveratrol (In vitro Study)

Zaid, O. A. A., Hussein, S., El-Sonbaty, S., & Afifi, M. (2021) · Benha veterinary medical journal · doi:10.21608/bvmj.2021.73288.1401 · Cited by 1

M11-03: Natural agents for chemoprevention

Surh, Y. (2007) · Journal of Thoracic Oncology · doi:10.1097/01.jto.0000282963.30308.d8 · Cited by 1

Ação Quimiopreventiva dos Fitoquímicos por meio da Regulação do Fator de Transcrição Nrf2: Revisão Integrativa da Literatura

Oliveira, R. D. S., Silva, W. M., Prati, W. J., Rufino, P. C. H., Santana, R. P. D. V. F., Bassoli, B. K., & da Silva, F. C. (2020) · Revista Brasileira de Cancerologia · doi:10.32635/2176-9745.rbc.2020v66n1.428 · Cited by 1

Dietary Isoflavones: Cardiovascular Actions and Activation of Cellular Signaling Pathways

Siow, R. C. M., & Mann, G. E. (2009) · Wiley eBooks · doi:10.1002/9780470531792.ch12 · Cited by 1

Resveratrol: The Biochemistry Behind Its Anticancer Effects

Kundu, J. K., & Surh, Y. (2009) · doi:10.1002/9780470531792.ch15 · Cited by 1

Amelioration of oxidative stress in human endothelial cells by caffeic acid phenethyl ester (CAPE) and fluorinated derivatives (FCAPES) and pharmacokinetic characterization of CAPE and FCAPE in rats

Wang, X. (2007) · Texas ScholarWorks (Texas Digital Library) · Cited by 1

The role of resveratrol treatment and regular physical activity on sirtuins in brain of rats artificially selected for intrinsic aerobic running capacity

Szűcs, L. (2015) · REAL-PhD (Hungarian Academy of Sciences) · doi:10.17624/tf.2015.03 · Cited by 1

Inflammaging: investigação sobre envelhecimento cutâneo, imunossenescência e SARS-CoV-2

Fernandes, I. G. (2023) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2023.tde-08042024-124045 · Cited by 1

Oxidative stress and XIAP signalling in neuronal cells

Kairisalo, M. (2010) · Työväentutkimus Vuosikirja

Induction of Quinone Reductase NQO1 by Resveratrol in Human K562 Cells Involves the Antioxidant Response Element ARE and is Accompanied by Nuclear Translocation of Transcription Factor Nrf2

WU, J. M., Hsieh, T., Lu, X., & Wang, Z. (2006) · Medicinal Chemistry · doi:10.2174/157340606776930709 · Cited by 107

Induction of quinone reductase NQO1 by resveratrol involves antioxidant response element ARE and is accompanied by nuclear translocation of transcription factor Nrf2

Hsieh, T., Lu, X., Wang, Z., & WU, J. M. (2006) · The FASEB Journal · doi:10.1096/fasebj.20.4.a82 · Cited by 3

Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells

Juan, S., Cheng, T., Lin, H., Chu, Y.-L., & Lee, W. (2004) · Biochemical Pharmacology · doi:10.1016/j.bcp.2004.09.015 · Cited by 153

Potential Mechanism of Blood Vessels Protection by Resveratrol, a Red Wine Component

阮淑慧, & ;, J. S. L. Y. C. T. ;. (2004) · Taipei Medical University Repository

Nrf2–Keap1 pathway–mediated effects of resveratrol on oxidative stress and apoptosis in hydrogen peroxide–treated rheumatoid arthritis fibroblast‐like synoviocytes

Zhang, Y., Wang, G., Wang, T., Cao, W., Zhang, L., & Chen, X. (2019) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.14196 · Cited by 102