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CCI52 sensitizes tumors to 6-mercaptopurine and inhibits MYCN-amplified tumor growth
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“Previous studies have demonstrated that Ceefourin-1 is a highly specific inhibitor of ABCC459–62, effectively blocking the transport of its substrates such as 6-mercaptopurine (6-MP), cAMP, D-luciferin, and estradiol-17β-glucuronide (E217βG), without exerting detectable effects on related transporters MRP1, MRP2, MRP3 or MRP5.”
From ABCC4 impairs the clearance of plasma LDL cholesterol through suppressing LDLR expression in the liver (2025) · cites this paper as [60]
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Karran, P., & Attard, N. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2292 · Cited by 477
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Research works printed but not linked: 31
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Cited by
Sorted by citations
Chen, J., Huang, H., Chen, C., Xia, G., Huang, H., Xiong, Y., Luo, P., Chen, Y., Li, J., Wen, L., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-08818-x · Cited by 1
Metadata
- Authors
- Huynh, T., Murray, J., Flemming, C. L., Kamili, A., Hofmann, U., Cheung, L., Roundhill, E. A., Yu, D. M. T., Webber, H. T., Schwab, M., Henderson, M. J., Haber, M., Norris, M. D., & Fletcher, J. I.
- Venue
- Biochemical Pharmacology
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 172
- Pages
- 113770
- ISSN
- 0006-2952
- Cited by
- 5
- References
- 1
- Language
- en
- Funders
- Cancer Institute NSW
- National Health and Medical Research Council
- Robert Bosch Stiftung
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