The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages
Open accessAbstract
Due to advances in stem cell biology, embryonic stem (ES) cells can be induced to differentiate into a particular mature cell lineage when cultured as embryoid bodies. Although transplantation of ES cells-derived neural progenitor cells has been demonstrated with some success for either spinal cord injury repair in small animal model, control of ES cell differentiation into complex, viable, higher ordered tissues is still challenging. Mouse ES cells have been induced to become neural progenitors by adding retinoic acid to embryoid body cultures for 4 days. In this study, we examine the use of electrospun biodegradable polymers as scaffolds not only for enhancing the differentiation of mouse ES cells into neural lineages but also for promoting and guiding the neurite outgrowth. A combination of electrospun fiber scaffolds and ES cells-derived neural progenitor cells could lead to the development of a better strategy for nerve injury repair.
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Cites
Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
Ying, Q.-L., Stavridis, M., Griffiths, D., Li, M., & Smith, A. (2003) · Nature Biotechnology · doi:10.1038/nbt780 · Cited by 1,504
Cited by
Electrospun Nanofibers: New Concepts, Materials, and Applications
Xue, J., Xie, J., Liu, W., & Xia, Y. (2017) · Accounts of Chemical Research · doi:10.1021/acs.accounts.7b00218 · Cited by 1,195
Self-citationFrom basics to clinical: A comprehensive review on spinal cord injury
Silva, N. A., Sousa, N., Reis, R. L., & Salgado, A. J. (2014) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2013.11.002 · Cited by 814
Physical Cues of Biomaterials Guide Stem Cell Differentiation Fate
Higuchi, A., Ling, Q.-D., Chang, Y., Hsu, S.-T., & Umezawa, A. (2013) · Chemical Reviews · doi:10.1021/cr300426x · Cited by 458
A review on fabrication of nanofibers via electrospinning and their applications
Islam, M. S., Ang, B. C., Andriyana, A., & Afifi, A. M. (2019) · SN Applied Sciences · doi:10.1007/s42452-019-1288-4 · Cited by 386
Laser-based direct-write techniques for cell printing
Schiele, N. R., Corr, D. T., Huang, Y., Raof, N. A., Xie, Y., & Chrisey, D. B. (2010) · Biofabrication · doi:10.1088/1758-5082/2/3/032001 · Cited by 334
Metadata
- Authors
- Xie, J., Willerth, S. M., Li, X., Macewan, M. R., Rader, A., Sakiyama-Elbert, S. E., & Xia, Y.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2009-01
- Volume
- 30
- Issue
- 3
- Pages
- 354-362
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2093483666
- Cited by
- 445
- References
- 1
- FWCI
- 10.77
- Type
- journal article
- Language
- en
- Open access
- green
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- Xie, J., Willerth, S. M., Li, X., Macewan, M. R., Rader, A., Sakiyama-Elbert, S. E., & Xia, Y. (2009). The differentiation of embryonic stem cells seeded on electrospun nanofibers into neural lineages. Biomaterials. https://doi.org/10.1016/j.biomaterials.2008.09.046
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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