The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Dual imaging-guided photothermal/photodynamic therapy using micelles
Open accessAbstract
We report a type of photosensitizer (PS)-loaded micelles integrating cyanine dye as potential theranostic micelles for precise anatomical tumor localization via dual photoacoustic (PA)/near-infrared fluorescent (NIRF) imaging modalities, and simultaneously superior cancer therapy via sequential synergistic photothermal therapy (PTT)/photodynamic therapy (PDT). The micelles exhibit enhanced photostability, cell internalization and tumor accumulation. The dual NIRF/PA imaging modalities of the micelles cause the high imaging contrast and spatial resolution of tumors, which provide precise anatomical localization of the tumor and its inner vasculature for guiding PTT/PDT treatments. Moreover, the micelles can generate severe photothermal damage on cancer cells and destabilization of the lysosomes upon PTT photo-irradiation, which subsequently facilitate synergistic photodynamic injury via PS under PDT treatment. The sequential treatments of PTT/PDT trigger the enhanced cytoplasmic delivery of PS, which contributes to the synergistic anticancer efficacy of PS. Our strategy provides a dual-modal cancer imaging with high imaging contrast and spatial resolution, and subsequent therapeutic synergy of PTT/PDT for potential multimodal theranostic application.
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Photoacoustic tomography: In vivo imaging from organelles to organs
Wang, L. V., & Hu, S. (2012) · Science · doi:10.1126/science.1216210 · Cited by 4,331
Accumulation of sub-100 nm polymeric micelles in poorly permeable tumours depends on size
Cabral, H., Matsumoto, Y., Mizuno, K., Chen, Q., Murakami, M., Kimura, M., Terada, Y., Kano, M. R., Miyazono, K., Uesaka, M., et al. (2011) · Nature Nanotechnology · doi:10.1038/nnano.2011.166 · Cited by 2,429
Cited by
Sheng, Z., Hu, D., Zheng, M., Zhao, P., Liu, H., Gao, D., Gong, P., Gao, G., Zhang, P., Ma, Y., et al. (2014) · ACS Nano · doi:10.1021/nn5062386 · Cited by 719
Wu, W., Mao, D., Hu, F., Xu, S., Chen, C., Zhang, C., Cheng, X., Yuan, Y., Ding, D., Kong, D., et al. (2017) · Advanced Materials · doi:10.1002/adma.201700548 · Cited by 462
Applications of polymer micelles for imaging and drug delivery
Movassaghian, S., Merkel, O. M., & Torchilin, V. P. (2015) · WIREs Nanomedicine and Nanobiotechnology · doi:10.1002/wnan.1332 · Cited by 276
Recent advances in different modal imaging-guided photothermal therapy
Chen, Q., Wen, J., Li, H., Xu, Y., Liu, F., & Sun, S. (2016) · Biomaterials · doi:10.1016/j.biomaterials.2016.08.022 · Cited by 265
Recent progress on nanoparticle-based drug delivery systems for cancer therapy
Xin, Y., Yin, M., Zhao, L., Meng, F., & Luo, L. (2017) · Cancer Biology & Medicine · doi:10.20892/j.issn.2095-3941.2017.0052 · Cited by 250
Metadata
- Authors
- Guo, M., Mao, H., Li, Y., Zhu, A., He, H., Yang, H., Wang, Y., Tian, X., Ge, C., Peng, Q., Wang, X., Yang, X., Chen, X., Liu, G., & Chen, H.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2014-05
- Volume
- 35
- Issue
- 16
- Pages
- 4656-4666
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2089354064
- Cited by
- 234
- References
- 2
- FWCI
- 18.37
- Type
- journal article
- Language
- en
- Open access
- green
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- Guo, M., Mao, H., Li, Y., Zhu, A., He, H., Yang, H., Wang, Y., Tian, X., Ge, C., Peng, Q., Wang, X., Yang, X., Chen, X., Liu, G., & Chen, H. (2014). Dual imaging-guided photothermal/photodynamic therapy using micelles. Biomaterials. https://doi.org/10.1016/j.biomaterials.2014.02.018
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