The DOI matches its Crossref record; 38 of the 38 references it cites were found in a registry or an index.
A Highly Efficient and Photostable Photosensitizer with Near‐Infrared Aggregation‐Induced Emission for Image‐Guided Photodynamic Anticancer Therapy
Abstract
Photodynamic therapy (PDT), which relies on photosensitizers (PS) and light to generate reactive oxygen species to kill cancer cells or bacteria, has attracted much attention in recent years. PSs with both bright emission and efficient singlet oxygen generation have also been used for image‐guided PDT. However, simultaneously achieving effective 1 O 2 generation, long wavelength absorption, and stable near‐infrared (NIR) emission with low dark toxicity in a single PS remains challenging. In addition, it is well known that when traditional PSs are made into nanoparticles, they encounter quenched fluorescence and reduced 1 O 2 production. In this contribution, these challenging issues have been successfully addressed through designing the first photostable photosensitizer with aggregation‐induced NIR emission and very effective 1 O 2 generation in aggregate state. The yielded nanoparticles show very effective 1 O 2 generation, bright NIR fluorescence centered at 820 nm, excellent photostability, good biocompatibility, and negligible dark in vivo toxicity. Both in vitro and in vivo experiments prove that the nanoparticles are excellent candidates for image‐guided photodynamic anticancer therapy.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Aggregation-Induced Emission: Together We Shine, United We Soar!
Mei, J., Leung, N. L. C., Kwok, R. T. K., Lam, J. W. Y., & Tang, B. Z. (2015) · Chemical Reviews · doi:10.1021/acs.chemrev.5b00263 · Cited by 8,270
Highly efficient organic light-emitting diodes from delayed fluorescence
Uoyama, H., Goushi, K., Shizu, K., Nomura, H., & Adachi, C. (2012) · Nature · doi:10.1038/nature11687 · Cited by 8,188
Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review
Maeda, H., Wu, J., Sawa, T., Matsumura, Y., & Hori, K. (2000) · Journal of Controlled Release · doi:10.1016/s0168-3659(99)00248-5 · Cited by 6,565
Aggregation‐Induced Emission: The Whole Is More Brilliant than the Parts
Mei, J., Hong, Y., Lam, J. W. Y., Qin, A., Tang, Y., & Tang, B. Z. (2014) · Advanced Materials · doi:10.1002/adma.201401356 · Cited by 3,381
Nanoparticles in Photodynamic Therapy
Lucky, S. S., Soo, K. C., & Zhang, Y. (2015) · Chemical Reviews · doi:10.1021/cr5004198 · Cited by 2,980
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
Zhou, Z., Song, J., Nie, L., & Chen, X. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00271d · Cited by 2,098
Photosensitizers of the porphyrin and phthalocyanine series for photodynamic therapy
Bonnett, R. (1995) · Chemical Society Reviews · doi:10.1039/cs9952400019 · Cited by 2,039
The role of porphyrin chemistry in tumor imaging and photodynamic therapy
Ethirajan, M., Chen, Y., Joshi, P., & Pandey, R. K. (2011) · Chem. Soc. Rev. · doi:10.1039/b915149b · Cited by 2,034
Overcoming the Achilles' heel of photodynamic therapy
Fan, W., Huang, P., & Chen, X. (2016) · Chemical Society Reviews · doi:10.1039/c6cs00616g · Cited by 1,684
Nano-graphene in biomedicine: theranostic applications
Yang, K., Feng, L., Shi, X., & Liu, Z. (2013) · Chem. Soc. Rev. · doi:10.1039/c2cs35342c · Cited by 1,634
Cited by
Recent Strategies to Develop Innovative Photosensitizers for Enhanced Photodynamic Therapy
Pham, T. C., Nguyen, V.-N., Choi, Y., Lee, S., & Yoon, J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00381 · Cited by 1,813
Photosensitizers for Photodynamic Therapy
Lan, M., Zhao, S., Liu, W., Lee, C., Zhang, W., & Wang, P. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201900132 · Cited by 1,081
Aggregation-induced emission: fundamental understanding and future developments
Chen, Y., Lam, J. W. Y., Kwok, R. T. K., Liu, B., & Tang, B. Z. (2019) · Materials Horizons · doi:10.1039/c8mh01331d · Cited by 891
Self-citationPhotosensitizers with Aggregation‐Induced Emission: Materials and Biomedical Applications
Hu, F., Xu, S., & Liu, B. (2018) · Advanced Materials · doi:10.1002/adma.201801350 · Cited by 859
Self-citationPhototherapy in cancer treatment: strategies and challenges
Cai, Y., Chai, T., Nguyen, W., Liu, J., Xiao, E., Ran, X., Ran, Y., Du, D., Chen, W., & Chen, X. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02140-y · Cited by 453
Metadata
- Authors
- Wu, W., Mao, D., Hu, F., Xu, S., Chen, C., Zhang, C., Cheng, X., Yuan, Y., Ding, D., Kong, D., & Liu, B.
- Venue
- Advanced Materials
- Publisher
- Wiley
- Published
- 2017-07-03
- Volume
- 29
- Issue
- 33
- ISSN
- 0935-9648 (ISSN-L)
- 1521-4095
- OpenAlex
- W2729463162
- Cited by
- 462
- References
- 38
- FWCI
- 38.88
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: A Highly Efficient and Photostable Photosensitizer with Near‐Infrared Aggregation‐Induced Emission for Image‐Guided Photodynamic Anticancer Therapy. https://app.cochat.ai/papers/10.1002/adma.201700548
- The paper
- Wu, W., Mao, D., Hu, F., Xu, S., Chen, C., Zhang, C., Cheng, X., Yuan, Y., Ding, D., Kong, D., & Liu, B. (2017). A Highly Efficient and Photostable Photosensitizer with Near‐Infrared Aggregation‐Induced Emission for Image‐Guided Photodynamic Anticancer Therapy. Advanced Materials. https://doi.org/10.1002/adma.201700548
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
