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Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery
Open accessAbstract
Mesoporous silica material with organo-bridged silsesquioxane frameworks is a kind of synergistic combination of inorganic silica, mesopores and organics, resulting in some novel or enhanced physicochemical and biocompatible properties compared with conventional mesoporous silica materials with pure Si-O composition. With the rapid development of nanotechnology, monodispersed nanoscale periodic mesoporous organosilica nanoparticles (PMO NPs) and organo-bridged mesoporous silica nanoparticles (MSNs) with various organic groups and structures have recently been synthesized from 100%, or less, bridged organosilica precursors, respectively. Since then, these materials have been employed as carrier platforms to construct bioimaging and/or therapeutic agent delivery nanosystems for nano-biomedical application, and they demonstrate some unique and/or enhanced properties and performances. This review article provides a comprehensive overview of the controlled synthesis of PMO NPs and organo-bridged MSNs, physicochemical and biocompatible properties, and their nano-biomedical application as bioimaging agent and/or therapeutic agent delivery system.
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Cites
On the controllable soft-templating approach to mesoporous silicates
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Hybrid organic–inorganic materials: a land of multidisciplinarity
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Nanomedicine therapeutic approaches to overcome cancer drug resistance
Markman, J. L., Rekechenetskiy, A., Holler, E., & Ljubimova, J. Y. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.09.019 · Cited by 733
Role of integrated cancer nanomedicine in overcoming drug resistance
Iyer, A. K., Singh, A., Ganta, S., & Amiji, M. M. (2013) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2013.07.012 · Cited by 343
Kim, J. H., Fang, B., Song, M. Y., & Yu, J.-S. (2012) · Chemistry of Materials · doi:10.1021/cm203520a · Cited by 72
Cited by
Croissant, J. G., Fatieiev, Y., Almalik, A., & Khashab, N. M. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201700831 · Cited by 594
Metadata
- Authors
- Du, X., Li, X., Xiong, L., Zhang, X., Kleitz, F., & Qiao, S. Z.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2016-06
- Volume
- 91
- Pages
- 90-127
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2297594477
- Cited by
- 262
- References
- 6
- FWCI
- 18.77
- Type
- journal article
- Language
- en
- Open access
- green
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- Du, X., Li, X., Xiong, L., Zhang, X., Kleitz, F., & Qiao, S. Z. (2016). Mesoporous silica nanoparticles with organo-bridged silsesquioxane framework as innovative platforms for bioimaging and therapeutic agent delivery. Biomaterials. https://doi.org/10.1016/j.biomaterials.2016.03.019
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