The DOI matches its Crossref record; 142 of the 142 references it cites were found in a registry or an index.
Emerging and innovative approaches for wound healing and skin regeneration: Current status and advances
Abstract
Current advances in skin tissue engineering and wound healing augur well for the development of split or full thickness skin substitutes to recapitulating the native functional skin. These engineered skin substitutes have fared successfully in recent years with exploration of various emerging technologies. As a result, recent clinical practice has been highly evolved incorporating various engineered skin substitutes as an adjunct to accelerate healing and improvement of quality of life in long-term. This review seeks to bring the researchers through various emerging and innovative approaches being developed and utilized for accelerating wound healing and skin regeneration. In order to attempt this, we reviewed various design considerations for skin repair and impact of several smart technologies viz., in situ 3D printing, portable bioprinters, electrosprayers and in situ forming hydrogels that have significantly improved wound healing and skin therapeutics. Furthermore, numerous cellular therapies such as effect of immunomodulation, stromal vascular fraction treatments, micro RNA (miRNA) and small interfering RNA (siRNA) based skin therapeutics have been thoroughly discussed. Finally, an update of clinical trials along with critical analysis of properties and benefits of different emerging technologies in healing certain types of wounds, prime challenges and future prospects in skin tissue engineering are discussed.
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Cites
Electrospinning: A fascinating fiber fabrication technique
Bhardwaj, N., & Kundu, S. C. (2010) · Biotechnology Advances · doi:10.1016/j.biotechadv.2010.01.004 · Cited by 5,028
Self-citationWound Healing: A Cellular Perspective
Rodrigues, M., Kosaric, N., Bonham, C. A., & Gurtner, G. C. (2019) · Physiological Reviews · doi:10.1152/physrev.00067.2017 · Cited by 3,013
Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size
Loh, Q. L., & Choong, C. (2013) · Tissue Engineering Part B: Reviews · doi:10.1089/ten.teb.2012.0437 · Cited by 2,668
Wound healing and its impairment in the diabetic foot
Falanga, V. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67700-8 · Cited by 2,639
siRNA versus miRNA as therapeutics for gene silencing
Lam, J. K. W., Chow, M. Y. T., Zhang, Y., & Leung, S. W. S. (2015) · Molecular Therapy — Nucleic Acids · doi:10.1038/mtna.2015.23 · Cited by 1,081
Griffin, D. R., Weaver, W. M., Scumpia, P. O., Di Carlo, D., & Segura, T. (2015) · Nature Materials · doi:10.1038/nmat4294 · Cited by 981
Recent advances on the development of wound dressings for diabetic foot ulcer treatment—A review
Moura, L. I. F., Dias, A. M. A., Carvalho, E., & de Sousa, H. C. (2013) · Acta Biomaterialia · doi:10.1016/j.actbio.2013.03.033 · Cited by 778
Spiller, K. L., Nassiri, S., Witherel, C. E., Anfang, R. R., Ng, J., Nakazawa, K. R., Yu, T., & Vunjak-Novakovic, G. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2014.10.017 · Cited by 773
Ellis, S., Lin, E. J., & Tartar, D. (2018) · Current Dermatology Reports · doi:10.1007/s13671-018-0234-9 · Cited by 625
Cell proliferation and migration in silk fibroin 3D scaffolds
Mandal, B. B., & Kundu, S. C. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.02.006 · Cited by 583
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Cited by
Rational Design of Immunomodulatory Hydrogels for Chronic Wound Healing
Kharaziha, M., Baidya, A., & Annabi, N. (2021) · Advanced Materials · doi:10.1002/adma.202100176 · Cited by 721
Chronic wounds: Current status, available strategies and emerging therapeutic solutions
Las Heras, K., Igartua, M., Santos-Vizcaino, E., & Hernandez, R. M. (2020) · Journal of Controlled Release · doi:10.1016/j.jconrel.2020.09.039 · Cited by 370
Silk biomaterials in wound healing and skin regeneration therapeutics: From bench to bedside
Chouhan, D., & Mandal, B. B. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.11.050 · Cited by 348
Self-citation3D bioprinting for skin tissue engineering: Current status and perspectives
Weng, T., Zhang, W., Xia, Y., Wu, P., Yang, M., Jin, R., Xia, S., Wang, J., You, C., Han, C., et al. (2021) · Journal of Tissue Engineering · doi:10.1177/20417314211028574 · Cited by 303
In Situ 3D Bioprinting Living Photosynthetic Scaffolds for Autotrophic Wound Healing
Wang, X., Yang, C., Yu, Y., & Zhao, Y. (2022) · Research · doi:10.34133/2022/9794745 · Cited by 143
Metadata
- Authors
- Chouhan, D., Dey, N., Bhardwaj, N., & Mandal, B. B.
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2019-09
- Volume
- 216
- Pages
- 119267
- ISSN
- 0142-9612 (ISSN-L)
- OpenAlex
- W2950151274
- Cited by
- 522
- References
- 142
- FWCI
- 36.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chouhan, D., Dey, N., Bhardwaj, N., & Mandal, B. B. (2019). Emerging and innovative approaches for wound healing and skin regeneration: Current status and advances. Biomaterials. https://doi.org/10.1016/j.biomaterials.2019.119267
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
