Identification of novel acetylcholinesterase inhibitors: Indolopyrazoline derivatives and molecular docking studies

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Acetylcholinesterase and Its Inhibition in Alzheimer Disease

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Galantamine derivatives with indole moiety: Docking, design, synthesis and acetylcholinesterase inhibitory activity

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Synthesis of novel derivatives of oxindole, their urease inhibition and molecular docking studies

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1-N-Substituted thiocarbamoyl-3-phenyl-5-thienyl-2-pyrazolines: A novel cholinesterase and selective monoamine oxidase B inhibitors for the treatment of Parkinson's and Alzheimer's diseases

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New tetracyclic tacrine analogs containing pyrano[2,3-c]pyrazole: Efficient synthesis, biological assessment and docking simulation study

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Novel quinoline derivatives as potent in vitro α-glucosidase inhibitors: in silico studies and SAR predictions

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Novel 2,5-disubtituted-1,3,4-oxadiazoles with benzimidazole backbone: A new class of β-glucuronidase inhibitors and in silico studies

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In vitro evaluation and in silico screening of synthetic acetylcholinesterase inhibitors bearing functionalized piperidine pharmacophores

Brahmachari, G., Choo, C., Ambure, P. S., & Roy, K. (2015) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2015.06.005 · Cited by 55

In vitro antioxidant and cholinesterase inhibitory activities of methanolic fruit extract of Phyllanthus acidus

Moniruzzaman, M., Asaduzzaman, M., Hossain, M. S., Sarker, J., Rahman, S. M. A., Rashid, M., & Rahman, M. M. (2015) · BMC Complementary and Alternative Medicine · doi:10.1186/s12906-015-0930-y · Cited by 53

Synthesis of novel inhibitors of β-glucuronidase based on the benzothiazole skeleton and their molecular docking studies

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Synthesis, in vitro evaluation and molecular docking studies of biscoumarin thiourea as a new inhibitor of α-glucosidases

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Synthesis of novel benzohydrazone–oxadiazole hybrids as β-glucuronidase inhibitors and molecular modeling studies

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Indole Glucoalkaloids from Chimarrhis turbinata and Their Evaluation as Antioxidant Agents and Acetylcholinesterase Inhibitors

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Indole Alkaloids and Semisynthetic Indole Derivatives as Multifunctional Scaffolds Aiming the Inhibition of Enzymes Related to Neurodegenerative Diseases – A Focus on Psychotria L. Genus

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Synthesis and biological evaluation of some novel pyrazolines

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Prospective acetylcholinesterase inhibitory activity of indole and its analogs

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Synthesis of Some Phenylpyrazolo Benzimidazolo Quinoxaline Derivatives as Potent Antihistaminic Agents

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Identification of bisindolylmethane–hydrazone hybrids as novel inhibitors of β-glucuronidase, DFT, and in silico SAR intimations

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Cyclization of chalcones to isoxazole and pyrazole derivatives

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Additional acetyl cholinesterase inhibitory property of diaryl pyrazoline derivatives

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Synthesis and Evaluation of Anti-acetylcholinesterase Activity of 2-(2-(4-(2-Oxo-2-phenylethyl)piperazin-1-yl) ethyl)Isoindoline-1,3-dione Derivatives with Potential Anti-Alzheimer Effects.

Aliabadi, A., Foroumadi, A., Mohammadi-Farani, A., & Mahvar, M. G. (2013) · PubMed Central · Cited by 21

Untitled work

(2004) · Songklanakarin Journal of Science and Technology

Inhibitory potential of nitrogen, oxygen and sulfur containing heterocyclic scaffolds against acetylcholinesterase and butyrylcholinesterase

Obaid, R. J., Naeem, N., Mughal, E. U., Al‐Rooqi, M. M., Sadiq, A., Jassas, R. S., Moussa, Z., & Ahmed, S. A. (2022) · RSC Advances · doi:10.1039/d2ra03081k · Cited by 150

Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity

Özgün, D. Ö., Gul, H. I., Yamalı, C., Sakagami, H., Gülçın, İ., Sukuroglu, M. K., & Supuran, C. T. (2018) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2018.12.028 · Cited by 142

Current progress on antioxidants incorporating the pyrazole core

Silva, V. L. M., Elguero, J., & Silva, A. M. S. (2018) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2018.07.007 · Cited by 130

New Hybrid Hydrazinyl Thiazole Substituted Chromones: As Potential α-Amylase Inhibitors and Radical (DPPH & ABTS) Scavengers

Salar, U., Khan, K. M., Chigurupati, S., Taha, M., Wadood, A., Vijayabalan, S., Ghufran, M., & Perveen, S. (2017) · Scientific Reports · doi:10.1038/s41598-017-17261-w · Cited by 115

Synthesis, in vitro bio-evaluation, and molecular docking study of thiosemicarbazone-based isatin/bis-Schiff base hybrid analogues as effective cholinesterase inhibitors

Khan, S., Ullah, H., Hussain, R., Khan, Y., Khan, M. U., Khan, M., Sattar, A., & Khan, M. S. (2023) · Journal of Molecular Structure · doi:10.1016/j.molstruc.2023.135351 · Cited by 98

Synthesis of novel pyrazino[1,2-a]indol-1(2H)-one derivatives as potent cholinesterase inhibitors and their in vitro and in silico evaluations

Kuzu, B., & Demir, Y. (2025) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2025.110504 · Cited by 21

Design, Synthesis and Evaluation of 8‐(Piperazin‐1‐yl) Imidazo[1,2‐ a ]Pyrazine Derivatives as Acetylcholinesterase Inhibitors and Antioxidants

Wei, B.-B., Du, W.-R., Guo, X.-Y., Lan, Y. J., Shang, P.-P., Wang, X., & Ma, Z.-Y. (2024) · ChemistrySelect · doi:10.1002/slct.202400790 · Cited by 2

Isoindolone derivatives as novel potential anti-Alzheimer’s candidates: synthesis, in silico, and AChE inhibitory activity evaluation

Andrade‐Jorge, E., Rivera-Sánchez, F., Rodríguez, J. E., Lagos‐Cruz, J. A., Reyes-Vallejo, N., Villalobos‐Molina, R., Gallardo‐Ortíz, I. A., & Reyes‐Ramírez, A. (2022) · Medicinal Chemistry Research · doi:10.1007/s00044-022-02884-0 · Cited by 7

Structure-based identification of novel indole-fused polycyclic derivatives as potent acetylcholinesterase inhibitors

Chen, W., Zhan, K., Xu, C., Sun, S., Yang, X., & Lei, H. (2026) · Bioorganic & Medicinal Chemistry · doi:10.1016/j.bmc.2026.118765

Synthesis of Pyrazoline derivatives, condensation of β-dicarbonyl compounds with isoniazid (INH), and their biological evaluation as multitarget anti-Alzheimer’ disease agents

Kanwal, M., Sarwar, S., Nadeem, H., Zafar, R., & Rahman, K. M. (2023) · Chemical Papers · doi:10.1007/s11696-023-03224-1 · Cited by 6