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Deviant Matters: Duration, Frequency, and Intensity Deviants Reveal Different Patterns of Mismatch Negativity Reduction in Early and Late Schizophrenia
Abstract
Background A reduction in the size of the auditory event-related potential component known as mismatch negativity (MMN) is a consistent finding in schizophrenia. This study was designed to test the hypothesis that sound intensity and duration might be more sensitive to MMN reduction early in the development of schizophrenia because of the computational complexity in extracting these two sound dimensions.Methods The MMN elicited to sounds deviating in duration, frequency, or intensity was measured in participants with a short (n = 14, mean 2.6 years) and longer length of illness (n = 29, mean 18.9 years) relative to healthy age-matched control subjects.Results For participants early in the illness, a clear reduction was evident in MMN to duration and intensity but not frequency deviants. A different pattern was observed in patients with a longer length of illness--that is, a reduction in frequency and in duration to a lesser degree but not intensity MMN.Conclusions The results indicate a pronounced age-related decline in duration and intensity MMN in control subjects that might reduce the sensitivity of these indices in schizophrenia when measured later in the course of the illness. The MMN elicited to changes in different sound properties provides potentially complementary information on the onset and progression of neuropathological changes that underlie the reduction in MMN in schizophrenia.
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“Studies also reported that MMN in the classical oddball paradigm depends on stimulus, probability, and interstimulus interval (46, 47), so slight differences in procedures may lead to inconsistent findings among studies.”
From A Predictive Coding Perspective on Mismatch Negativity Impairment in Schizophrenia (2020) · cites this paper as [47]
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Cites
Transformed Up-Down Methods in Psychoacoustics
Levitt, H. (1971) · The Journal of the Acoustical Society of America · doi:10.1121/1.1912375 · Cited by 5,505
Risto, N. (2018) · Routledge eBooks · doi:10.4324/9780429487354 · Cited by 2,035
A Solution for Reliable and Valid Reduction of Ocular Artifacts, Applied to the P300 ERP
Semlitsch, H. V., Anderer, P., Schuster, P., & Presslich, O. (1986) · Psychophysiology · doi:10.1111/j.1469-8986.1986.tb00696.x · Cited by 2,024
McGuffin, P. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810320088015 · Cited by 1,483
Wijers, B. (1995) · Acta Psychologica · doi:10.1016/0001-6918(95)90043-8 · Cited by 1,319
Pantelis, C., Velakoulis, D., McGorry, P. D., Wood, S. J., John Suckling, A., Phillips, L., Yung, A. R., Bullmore, E. T., Brewer, W. J., Soulsby, B., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12323-9 · Cited by 1,309
The concept of auditory stimulus representation in cognitive neuroscience.
Näätänen, R., & Winkler, I. (1999) · Psychological Bulletin · doi:10.1037/0033-2909.125.6.826 · Cited by 1,069
Self-citationMismatch negativity in schizophrenia: a meta-analysis
Umbricht, D., & Krljes, S. (2005) · Schizophrenia Research · doi:10.1016/j.schres.2004.12.002 · Cited by 742
Memory‐based or afferent processes in mismatch negativity (MMN): A review of the evidence
Näätänen, R., Jacobsen, T., & Winkler, I. (2005) · Psychophysiology · doi:10.1111/j.1469-8986.2005.00256.x · Cited by 657
Self-citationBrain potential evidence for an auditory sensory memory deficit in schizophrenia
Catts, S. V., Shelley, A. M., Ward, P. B., Liebert, B. J., McConaghy, N., Andrews, S., & Michie, P. T. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.2.213 · Cited by 360
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Ye, H., Song, P., Xu, H., Li, Q., Chen, Y., Zhai, Y., Chang, C., Bao, X., Tanigawa, H., Tu, Z., et al. (2025) · Research · doi:10.34133/research.0960 · Cited by 4
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0003 · Cited by 5
Self-citationMultifeature Mismatch Negativity in Patients With Posttraumatic Stress Disorder
Löw, A., Frey, J. D., Gorzka, R., Engers, A., Wendt, M., Höllmer, H., & Jacobsen, T. (2018) · Clinical EEG and Neuroscience · doi:10.1177/1550059418814976 · Cited by 4
Abnormal Frequency Mismatch Negativity in Early Psychosis Outpatient Subjects
del Re, E. C., Maekawa, T., Mesholam‐Gately, R. I., Wojcik, J., Seidman, L. J., McCarley, R. W., & Niznikiewicz, M. A. (2019) · Clinical EEG and Neuroscience · doi:10.1177/1550059419886691 · Cited by 3
Guo, X., Yu, J., Quan, C., Xiao, J., Wang, J., Zhang, B., Hao, X., Wu, X., & Liang, J. (2024) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2024.02.004 · Cited by 2
Chien, Y., Hsieh, M. H., & Gau, S. S. (2024) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-024-06520-1 · Cited by 2
Early auditory impairments as a candidate marker of attenuated sensory symptoms of psychosis
Dondé, C., Palmer-Cooper, E. C., Gauld, C., Polosan, M., & Alderson‐Day, B. (2024) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2024.111214 · Cited by 2
NEUROPHYSIOLOGICAL CORRELATES OF EXCITEMENT IN MEN WITH RECENT-ONSET PSYCHOSIS
Sumich, A. L., Harris, A. W. F., Whitford, T. J., Hermens, D. F., Heym, N., Anderson, J. D., Bloxsom, C. A. J., Kibowski, F., & Kumari, V. (2018) · Psychiatria Danubina · doi:10.24869/psyd.2018.64 · Cited by 2
Brain imaging correlates of emerging schizophrenia
Ehlkes, T., Michie, P. T., & Schall, U. (2012) · Neuropsychiatry · doi:10.2217/npy.12.13 · Cited by 2
Self-citationAuditory event-related potentials in patients with psychotic illness: A 5-year follow-up
Valkonen‐Korhonen, M., Tarkka, I. M., Pääkkönen, A. K., & Purhonen, M. (2011) · Neurocase · doi:10.1080/13554794.2011.627337 · Cited by 2
Can new paradigms bring new perspectives for mismatch negativity studies in schizophrenia?
Jarkiewicz, M., & Wichniak, A. (2015) · Neuropsychiatric Electrophysiology · doi:10.1186/s40810-015-0010-z · Cited by 2
Osakabe, Y., Shiga, T., Hoshino, H., Kanno, K., Wada, T., Ochiai, H., Itagaki, S., Miura, I., & Yabe, H. (2020) · European Journal of Neuroscience · doi:10.1111/ejn.14668 · Cited by 2
Self-citationvan Themaat, A. H. V. L., Oranje, B., Larsen, K. M., Tomasevic, L., Johnsen, L. K., Thorup, A. A. E., Plessen, K. J., Siebner, H. R., & Nordentoft, M. (2022) · Schizophrenia Research · doi:10.1016/j.schres.2022.06.035 · Cited by 2
Event-related potential (ERP) markers of 22q11.2 deletion syndrome and associated psychosis
Francisco, A. A., Foxe, J. J., & Molholm, S. (2023) · Journal of Neurodevelopmental Disorders · doi:10.1186/s11689-023-09487-9 · Cited by 2
Winterer, G. (2009) · Springer eBooks · doi:10.1007/978-1-4020-9464-4_4 · Cited by 2
Boshra, R., Dhindsa, K., Boursalie, O., Ruiter, K. I., Sonnadara, R., Samavi, R., Doyle, T. E., Reilly, J. P., & Connolly, J. F. (2023) · doi:10.32920/24132900.v1 · Cited by 2
Mismatch negativity deficits in schizophrenia and bipolar disorder
Du, L., Jiao, X., Shi, K., Mo, D., Zhou, J., Shi, Y., Zhang, X., Zeng, Z., Li, H., Duan, D., et al. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.05.037 · Cited by 4
Chien, Y., Chen, C., Hsieh, M. H., & Gau, S. S. (2025) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2025.111552 · Cited by 1
Hua, J. P. Y., Roach, B. J., Hamilton, H. K., Bachman, P. M., Belger, A., Carrión, R. E., Duncan, E., Johannesen, J., Light, G. A., Niznikiewicz, M., et al. (2025) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2025.100664 · Cited by 1
Wei, A., Gao, R.-J., Fan, M., Luan, P., Kong, L., & He, X. (2026) · BMC Psychiatry · doi:10.1186/s12888-026-07786-8 · Cited by 1
Wynn, J. K. (2023) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2023.10.002 · Cited by 1
Korostenskaja, M. (2008) · Työväentutkimus Vuosikirja
Jarkiewicz, M., Okruszek, Ł., Jernajczyk, W., Waliniowska, E., & Wichniak, A. (2014) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(14)70269-x
PHENOTYPING OF SCHIZOPHRENIA BY MULTI-MODAL BRAIN IMAGING
Schall, U., Rasser, P. E., Fulham, W. R., Todd, J., Michie, P. T., Ward, P. B., Johnston, P., & Thompson, P. M. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.02.906
Self-citationP.1.b.006 Role of striatal cholinergic interneurons in attention during learning in the rat
Aoki, S., Liu, A. W., Zucca, A., & Wickens, J. R. (2014) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(14)70267-6
Chapitre 5 – Potentiels évoqués cognitifs et troubles psychiatriques
Cermolacce, M., Faugère, M., & Steffen, M. L. (2015) · doi:10.1016/b978-2-294-74086-2.00005-8
Impey, D. (2016) · uO Research (University of Ottawa) · doi:10.20381/ruor-534
Inhibition of Gamma Oscillations in Healthy Subjects and Patients with Schizophrenia
Farzan, F. (2011) · TSpace (University of Toronto)
Matziorinis, A. M., Moberget, T., & Elvsåshagen, T. (2017) · NORA - Norwegian Open Research Archives · doi:10.13140/rg.2.2.33351.52644
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0002
Self-citationElectroencephalography and Staging
Lavoie, S. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139839518.010
矢部, 博., 高橋, 雄., 菅野, 和., 星野, 大., 日野, 瑞., 戸田, 亘., 堀越翔, 志賀, 哲., 國井, 泰., 三浦, 至., et al. (2020) · 日本生物学的精神医学会誌 = Japanese journal of biological psychiatry · doi:10.11249/jsbpjjpp.31.3_127
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刑部, 有., 和田, 知., 松本, 貴., 三浦, 至., & 矢部, 博. (2021) · 臨床神経生理学 · doi:10.11422/jscn.49.158
Näätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0008
Self-citationNäätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0005
Self-citationNäätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0004
Self-citationNäätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0007
Self-citationNäätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.003.0006
Self-citationAbalo‐Rodríguez, I., & Moratti, S. (2022) · doi:10.31219/osf.io/hzusb
Boshra, R., Dhindsa, K., Boursalie, O., Ruiter, K. I., Sonnadara, R., Samavi, R., Doyle, T. E., Reilly, J. P., & Connolly, J. F. (2023) · doi:10.32920/24132900
Alho, K., Escera, C., Kujala, T., Schröger, E., Tervaniemi, M. H., Winkler, I., & Yabe, H. (2023) · Psychophysiology · doi:10.1111/psyp.14504
Self-citationNäätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.002.0007
Self-citationNäätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.002.0003
Self-citationNäätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.002.0010
Self-citationNäätänen, R., Kujala, T., & Light, G. A. (2019) · Oxford University Press eBooks · doi:10.1093/oso/9780198705079.002.0005
Self-citationBose, A., Nayok, S. B., Pathak, H., Bagali, K. B., Chhabra, H., Suhas, S., Shivakumar, V., Sreeraj, V. S., Narayanaswamy, J. C., & Venkatasubramanian, G. (2024) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2024.104158
Jiao, X., Hu, Q., Zhu, W., Ren, W., Bu, Y., Miao, W., Song, C., Sun, J., Li, C., & Wang, J. (2025) · Schizophrenia Research · doi:10.1016/j.schres.2025.01.030
Hierarchical predictive processing in the brain: Predictive coding and its neural signatures
Huang, Y. T., & Chao, Z. C. (2025) · The Psychology of learning and motivation/The psychology of learning and motivation · doi:10.1016/bs.plm.2025.03.004 · Cited by 1
Auditory Processing Deficits in Bipolar Disorder with and without a History of Psychotic Features
Verbiest, R. (2020) · Digital Scholarship - UNLV (University of Nevada Reno) · doi:10.34917/6456455
Dark, F. L., Newman, E., Gore‐Jones, V., Monte, V. E. D., Garrido, M. I., & Dzafic, I. (2020) · Figshare · doi:10.6084/m9.figshare.13023318
Ćurić, S., Haaf, M., Zokai, D., Korkutan, T., Steinmann, S., Rauh, J., Mulert, C., & Leicht, G. (2025) · Schizophrenia Bulletin · doi:10.1093/schbul/sbaf227
Caulfield, A., Moura, R., Brugger, S. P., Young, A. H., Mehta, M. A., Adams, R. A., & Beck, K. (2026) · Journal of Psychopharmacology · doi:10.1177/02698811261436604
Ragalmuto, F., Oranje, B., & Ziermans, T. B. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106764
Soltanzadeh, M., Ameis, S. H., Charlton, C. E., Cleverley, K., Courtney, D., Dickie, E. W., Felsky, D., Foussias, G., Goldstein, B. I., Griffiths, J. D., et al. (2026) · medRxiv · doi:10.64898/2026.06.24.26356447
Metadata
- Authors
- Todd, J., Michie, P. T., Schall, U., Karayanidis, F., Yabe, H., & Näätänen, R.
- Affiliations
- Hunter Medical Research Institute (AU)
- Hirosaki University (JP)
- University of Helsinki (FI)
- Corresponding author
- Todd, Juanita
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2008-01
- Volume
- 63
- Issue
- 1
- Pages
- 58-64
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2016957475
- Cited by
- 257
- References
- 29
- Citations by year
- 2026: 4 · 2025: 10 · 2024: 11 · 2023: 15 · 2022: 10 · 2021: 8 · 2020: 20 · 2019: 34 · 2018: 14 · 2017: 26 · 2016: 10 · 2015: 24 · 2014: 14 · 2013: 12 · 2012: 10
- FWCI
- 4.44
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biological Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- NOVA (University of Newcastle Australia) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
- Keywords
- mismatch negativity, schizophrenia, auditory event-related potentials, length of illness, early-onset schizophrenia, auditory processing deficits
- MeSH terms
- Acoustic Stimulation, Adolescent, Adult, Aged, Analysis of Variance, Contingent Negative Variation, Dose-Response Relationship, Radiation, Electroencephalography, Evoked Potentials, Auditory, Female, Humans, Longitudinal Studies, Male, Middle Aged, Reaction Time, Schizophrenia, Schizophrenic Psychology, Time Factors, Case-Control Studies
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