Scale-up cultivation of Chlorella ellipsoidea from indoor to outdoor in bubble column bioreactors
Open accessAbstract
The cultivation of Chlorella ellipsoidea in bubble column bioreactors was investigated at different scales under indoor and outdoor conditions. The algal cells were able to quickly adapt to the outdoor conditions and achieved a growth rate of 31.55mg L(-1)day(-1). Due to differences in light and temperature, the outdoor culture produced a higher percentage of unsaturated fatty acids compared to the indoor cultures, while the amino acid composition was unaffected. The overall cost of the biomass produced by the 200L outdoor cultivation (58.70US$/kg-dry weight) was estimated to be more than 7 times lower than that of the 20L indoor cultivation (431.39US$/kg-dry weight). Together these results provide a basis for the cultivation of C. ellipsoidea for the large-scale production of biofuels, high-value nutrients and/or recombinant proteins.
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Strategic application of various stress stimuli is used for enhancing production of lipid or other molecules, strategies varying according to microalgae employed.
“Strategic application of various stress stimuli in culture is used for enhancing the production of lipid or other molecules of interest, the strategies varying according to microalgae employed (Wang et al. 2014).”
From Production of microalgae with high lipid content and their potential as sources of nutraceuticals (2023) · cites this paper as Wang et al. 2014
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Highly efficient expression of rabbit neutrophil peptide-1 gene in Chlorella ellipsoidea cells
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Production of microalgae with high lipid content and their potential as sources of nutraceuticals
Udayan, A., Pandey, A. K., Sirohi, R., Sreekumar, N., Sang, B.-I., Sim, S. J., Kim, S. H., & Pandey, A. (2023) · Phytochemistry Reviews · doi:10.1007/s11101-021-09784-y · Cited by 302 · see citing works
“Strategic application of various stress stimuli in culture is used for enhancing the production of lipid or other molecules of interest, the strategies varying according to microalgae employed (Wang et al. 2014).”
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- Authors
- Wang, S.-K., Hu, Y.-R., Wang, F., Stiles, A. R., & Liu, C.-Z.
- Affiliations
- Chinese Academy of Sciences (CN)
- University of California, Berkeley (US)
- Venue
- Bioresource Technology
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 156
- Pages
- 117-122
- ISSN
- 0960-8524 (ISSN-L)
- OpenAlex
- W2081330129
- Cited by
- 58
- References
- 2
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 3 · 2020: 4 · 2019: 6 · 2018: 5 · 2017: 5 · 2016: 8 · 2015: 10 · 2014: 3
- FWCI
- 2.86
- Type
- journal article
- Language
- en
- Open access
- green
- ir.ipe.ac.cn
- Licence
- cc-by-nc-sa
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- Locations
- Bioresource Technology (publishedVersion)
- PubMed (publishedVersion)
- Institute of Process Engineering, CAS Institutional Repository (submittedVersion, cc-by-nc-sa)
- Funders
- Major State Basic Research Development Program (2011CB200903)
- Knowledge Innovation Program of the Chinese Academy of Sciences (YZ200947)
- Chinese Academy of Sciences Fellowships for Young International Scientists (2011Y1GA01)
- Topics
- Physical Sciences › Energy › Renewable Energy, Sustainability and the Environment › Algal biology and biofuel production
- Physical Sciences › Engineering › Biomedical Engineering › Fluid Dynamics and Mixing
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Aquaculture Nutrition and Growth
- Keywords
- Chlorella ellipsoidea, bubble column bioreactor, open-field cultivation, indoor cultivation, unsaturated fatty acids, amino acid composition, cost of cultivation, microalgae cultivation, biofuel feedstock
- MeSH terms
- Amino Acids, Chlorella, Costs and Cost Analysis, Fatty Acids, Kinetics, Cell Culture Techniques, Bioreactors, Algal Proteins
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