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The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.

Recent advances in high-sensitivity detection methods for paper-based lateral-flow assay

Nguyen, Van-Thuan, Song, Seungri, Park, Seungkyung, Joo, Chulmin·2020·Biosensors and Bioelectronics

Abstract

Paper-based lateral-flow assays (LFAs) have achieved considerable commercial success and continue to have a significant impact on medical diagnostics and environmental monitoring. Conventional LFAs are typically performed by examining the color changes in the test bands by naked eye. However, for critical biochemical markers that are present in extremely small amounts in the clinical specimens, this readout method is not quantitative, and does not provide sufficient sensitivity or suitable detection limit for a reliable assay. Diverse technologies for high-sensitivity LFA detection have been developed and commercialization efforts are underway. In this review, we aim to provide a critical and objective overview of the recent progress in high-sensitivity LFA detection technologies, which involve the exploitation of the physical and chemical responses of transducing particles. The features and biomedical applications of the technologies, along with future prospects and challenges, are also discussed.

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Metadata

Authors
Nguyen, V.-T., Song, S., Park, S., & Joo, C.
Venue
Biosensors and Bioelectronics
Publisher
Elsevier BV
Published
2020-03
Volume
152
Pages
112015
ISSN
0956-5663 (ISSN-L)
OpenAlex
W3000338635
Cited by
373
References
63
FWCI
15.19
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Recent advances in high-sensitivity detection methods for paper-based lateral-flow assay. https://app.cochat.ai/papers/10.1016/j.bios.2020.112015
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Nguyen, V.-T., Song, S., Park, S., & Joo, C. (2020). Recent advances in high-sensitivity detection methods for paper-based lateral-flow assay. Biosensors and Bioelectronics. https://doi.org/10.1016/j.bios.2020.112015

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