The DOI matches its Crossref record; 97 of the 112 references it cites were found in a registry or an index.
Direct lactic acid fermentation: Focus on simultaneous saccharification and lactic acid production
Abstract
In the recent decades biotechnological production of lactic acid has gained a prime position in the industries as it is cost effective and eco-friendly. Lactic acid is a versatile chemical having a wide range of applications in food, pharmaceutical, leather and textile industries and as chemical feedstock for so many other chemicals. It also functions as the monomer for the biodegradable plastic. Biotechnological production is advantageous over chemical synthesis in that we can utilize cheap raw materials such as agro-industrial byproducts and can selectively produce the stereo isomers in an economic way. Simultaneous saccharification and fermentation can replace the classical double step fermentation by the saccharification of starchy or cellulosic biomass and conversion to lactic acid concurrently by adding inoculum along with the substrate degrading enzymes. It not only reduces the cost of production by avoiding high energy consuming biomass saccharification, but also provides the higher productivity than the single step conversion by the providing adequate sugar release.
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“In terms of nature, polylactic acid possesses good thermoplasticity and can be used to prepare and process plastics in order to make, for example, films and fibers [10,11].”
From Synthesis and Biological Application of Polylactic Acid (2020) · cites this paper as [11]
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Cites
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Sorted by citations
An overview of the recent developments in polylactide (PLA) research
Madhavan Nampoothiri, K., Nair, N. R., & John, R. P. (2010) · Bioresource Technology · doi:10.1016/j.biortech.2010.05.092 · Cited by 2,448
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Lactic acid as a platform chemical in the biobased economy: the role of chemocatalysis
Dusselier, M., Wouwe, P. V., Dewaele, A., Makshina, E. V., & Sels, B. F. (2013) · Energy & Environmental Science · doi:10.1039/c3ee00069a · Cited by 841
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Metadata
- Authors
- John, R. P., G.S., A., Nampoothiri, K. M., & Pandey, A.
- Affiliations
- National Institute for Interdisciplinary Science and Technology (IN)
- Corresponding author
- John, Rojan P.
- Venue
- Biotechnology Advances
- Publisher
- Elsevier BV
- Published
- 2009-03
- Volume
- 27
- Issue
- 2
- Pages
- 145-152
- ISSN
- 0734-9750 (ISSN-L)
- OpenAlex
- W2052869992
- Cited by
- 286
- References
- 112
- Citations by year
- 2026: 8 · 2025: 7 · 2024: 8 · 2023: 17 · 2022: 9 · 2021: 14 · 2020: 20 · 2019: 20 · 2018: 9 · 2017: 22 · 2016: 32 · 2015: 21 · 2014: 19 · 2013: 25 · 2012: 17
- FWCI
- 0.95
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biotechnology Advances (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
- Physical Sciences › Chemical Engineering › Catalysis › Catalysis for Biomass Conversion
- Keywords
- lactic acid production, simultaneous saccharification and fermentation, stereoisomers, agro-industrial by-products, cellulosic biomass, starch hydrolysis, sugar release, fermentation productivity
- MeSH terms
- Fermentation, Lactobacillus, Rhizopus, Starch, Biomass, Lactic Acid, Carbohydrate Metabolism
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