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Cited by 437

The DOI matches its Crossref record; 214 of the 214 references it cites were found in a registry or an index.

Silk fibroin/hydroxyapatite composites for bone tissue engineering

Open access
Farokhi, Mehdi, Mottaghitalab, Fatemeh, Samani, Saeed, Shokrgozar, Mohammad Ali, Kundu, Subhas C., Reis, Rui L., Fatahi, Yousef, Kaplan, David L.·2018·Biotechnology Advances

Abstract

Silk fibroin (SF) is a natural fibrous polymer with strong potential for many biomedical applications. SF has attracted interest in the field of bone tissue engineering due to its extraordinary characteristics in terms of elasticity, flexibility, biocompatibility and biodegradability. However, low osteogenic capacity has limited applications for SF in the orthopedic arena unless suitably functionalized. Hydroxyapatite (HAp) is a well-established bioceramic with biocompatibility and appropriate for constructing orthopedic and dental substitutes. However, HAp ceramics tend to be brittle which can restrict applications in the repair of load-bearing tissues such as bones. Therefore, blending SF and HAp combines the useful properties of both materials as bone constructs for tissue engineering, the subject of this review.

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Crossref · 10.1016/j.biotechadv.2017.10.001

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Metadata

Authors
Farokhi, M., Mottaghitalab, F., Samani, S., Shokrgozar, M. A., Kundu, S. C., Reis, R. L., Fatahi, Y., & Kaplan, D. L.
Venue
Biotechnology Advances
Publisher
Elsevier BV
Published
2018-01
Volume
36
Issue
1
Pages
68-91
ISSN
0734-9750 (ISSN-L)
OpenAlex
W2761370985
Cited by
437
References
214
FWCI
17.34
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Silk fibroin/hydroxyapatite composites for bone tissue engineering. https://app.cochat.ai/papers/10.1016/j.biotechadv.2017.10.001
The paper
Farokhi, M., Mottaghitalab, F., Samani, S., Shokrgozar, M. A., Kundu, S. C., Reis, R. L., Fatahi, Y., & Kaplan, D. L. (2018). Silk fibroin/hydroxyapatite composites for bone tissue engineering. Biotechnology Advances. https://doi.org/10.1016/j.biotechadv.2017.10.001

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