Recent advances in synthetic biology toolkits and metabolic engineering of Ralstonia eutropha H16 for production of value-added chemicals

Proteomic and Transcriptomic Elucidation of the Mutant Ralstonia eutropha G + 1 with Regard to Glucose Utilization

Raberg, M., Peplinski, K., Heiss, S., Ehrenreich, A., Voigt, B., Döring, C., Bömeke, M., Hecker, M., & Steinbüchel, A. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.02015-10 · Cited by 55

Studies on the aerobic utilization of synthesis gas (syngas) by wild type and recombinant strains of Ralstonia eutropha H16

Heinrich, D., Raberg, M., & Steinbüchel, A. (2017) · Microbial Biotechnology · doi:10.1111/1751-7915.12873 · Cited by 55

Lab-Scale Cultivation of Cupriavidus necator on Explosive Gas Mixtures: Carbon Dioxide Fixation into Polyhydroxybutyrate

Lambauer, V., & Kratzer, R. (2022) · Bioengineering · doi:10.3390/bioengineering9050204 · Cited by 55

Construction of a stable plasmid vector for industrial production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by a recombinant Cupriavidus necator H16 strain

Sato, S. A., Fujiki, T., & Matsumoto, K. (2013) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2013.05.026 · Cited by 54

Isolation of mutants of Alcaligenes eutrophus unable to derepress the fermentative alcohol dehydrogenase

Steinb�chel, A., Fr�nd, C., Jendrossek, D., & Schlegel, H. G. (1987) · Archives of Microbiology · doi:10.1007/bf00414809 · Cited by 54

Enhancement of glycerol utilization ability of Ralstonia eutropha H16 for production of polyhydroxyalkanoates

Fukui, T., Mukoyama, M., Orita, I., & Nakamura, S. (2014) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-014-5831-3 · Cited by 54

Polyhydroxyalkanoates: Basics, Production and Applications of Microbial Biopolyesters

Koller, M., Salerno, A., & Braunegg, G. (2013) · Wiley eBooks · doi:10.1002/9781118676646.ch7 · Cited by 54

Fermentation database mining by pattern recognition

Stephanopoulos, G. N., Locher, G., Duff, M. J., Kamimura, R. T., & Stephanopoulos, G. (1997) · Biotechnology and Bioengineering · doi:10.1002/(sici)1097-0290(19970305)53:5 · Cited by 53

Poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) terpolymer production from volatile fatty acids using engineered Ralstonia eutropha

Jung, H., Jeon, J.-M., Yi, D.-H., Song, H., Yang, S., Choi, T., Bhatia, S. K., Yoon, J., Kim, Y., Brigham, C. J., et al. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.07.091 · Cited by 53

Natural Functions of Bacterial Polyhydroxyalkanoates

Castro‐Sowinski, S., Burdman, S., Matan, O., & Okon, Y. (2009) · Microbiology monographs · doi:10.1007/978-3-642-03287-5_3 · Cited by 53

Versatile and stable vectors for efficient gene expression in Ralstonia eutropha H16

Gruber, S., Hagen, J., Schwab, H., & Heidinger, P. (2014) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2014.06.030 · Cited by 52

New Insight into the Role of the Calvin Cycle: Reutilization of CO2 Emitted through Sugar Degradation

Shimizu, R., Dempo, Y., Nakayama, Y., Nakamura, S., Bamba, T., Fukusaki, E., & Fukui, T. (2015) · Scientific Reports · doi:10.1038/srep11617 · Cited by 52

Microbial production of ethanol from acetate by engineered Ralstonia eutropha

Lee, H. M., Jeon, B.-Y., & Oh, M. (2016) · Biotechnology and Bioprocess Engineering · doi:10.1007/s12257-016-0197-2 · Cited by 52

The role of dissolved oxygen content as a modulator of microbial polyhydroxyalkanoate synthesis

Blunt, W. A., Sparling, R., Gapes, D. J., Levin, D. B., & Çiçek, N. (2018) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-018-2488-6 · Cited by 52

Co-conversion of lignocellulose-derived glucose, xylose, and aromatics to polyhydroxybutyrate by metabolically engineered Cupriavidus necator

Weng, C., Tang, R., Peng, X., & Han, Y. (2023) · Bioresource Technology · doi:10.1016/j.biortech.2023.128762 · Cited by 52

Production of PHB from Chicory Roots – Comparison of Three Cupriavidus necator Strains

Haas, C. (2015) · Chemical and Biochemical Engineering Quarterly · doi:10.15255/cabeq.2014.2250 · Cited by 51

Production of fatty acids in Ralstonia eutropha H16 by engineering β -oxidation and carbon storage

Chen, J. S., Colón, B. C., Dusel, B., Ziesack, M., Way, J. C., & Torella, J. P. (2015) · PeerJ · doi:10.7717/peerj.1468 · Cited by 51

A genome-scale metabolic model of Cupriavidus necator H16 integrated with TraDIS and transcriptomic data reveals metabolic insights for biotechnological applications

Pearcy, N., Garavaglia, M., Millat, T., Gilbert, J. P., Song, Y., Hartman, H. B., Woods, C., Tomi-Andrino, C., Bommareddy, R. R., Cho, B., et al. (2022) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1010106 · Cited by 51

From organic pollutants to bioplastics: insights into the bioremediation of aromatic compounds by Cupriavidus necator

Berezina, N., Yada, B., & Lefebvre, R. (2014) · New Biotechnology · doi:10.1016/j.nbt.2014.09.003 · Cited by 50

Extension of the Substrate Utilization Range of Ralstonia eutropha Strain H16 by Metabolic Engineering To Include Mannose and Glucose

Sichwart, S., Hetzler, S., Bröker, D., & Steinbüchel, A. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.01977-10 · Cited by 50

A Novel High-Cell-Density Protein Expression System Based on Ralstonia eutropha

Srinivasan, S., Barnard, G. C., & Gerngross, T. U. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.12.5925-5932.2002 · Cited by 50

Upgrading carbon monoxide to bioplastics via integrated electrochemical reduction and biosynthesis

Wi, T., Xie, Y., Levell, Z. H., Feng, D., Kim, J. Y., Zhu, P., Elgazzar, A., Jeon, T. H., Shakouri, M., Hao, S., et al. (2024) · Nature Synthesis · doi:10.1038/s44160-024-00621-6 · Cited by 50

Metabolic carbon fluxes and biosynthesis of polyhydroxyalkanoates in Ralstonia eutropha on short chain fatty acids.

Yu, J., & Si, Y. (2004) · Biotechnology Progress · doi:10.1021/bp034380e · Cited by 50

An Engineered Constitutive Promoter Set with Broad Activity Range for Cupriavidus necator H16

Johnson, A. O., González‐Villanueva, M., Tee, K. L., & Wong, T. S. (2018) · ACS Synthetic Biology · doi:10.1021/acssynbio.8b00136 · Cited by 49

Metabolic engineering of strains of Ralstonia eutropha and Pseudomonas putida for biotechnological production of 2-methylcitric acid

Ewering, C., Heuser, F., Benölken, J. K., Brämer, C. O., & Steinbüchel, A. (2006) · Metabolic Engineering · doi:10.1016/j.ymben.2006.05.007 · Cited by 48

Establishing Mixotrophic Growth of Cupriavidus necator H16 on CO2 and Volatile Fatty Acids

Jawed, K., Irorere, V. U., Bommareddy, R. R., Minton, N. P., & Kovács, K. (2022) · Fermentation · doi:10.3390/fermentation8030125 · Cited by 48

Problems and corresponding strategies for converting CO2 into value-added products in Cupriavidus necator H16 cell factories

Tang, R., Yuan, X.-Z., & Yang, J. (2023) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108183 · Cited by 48

Requirements for Construction of a Functional Hybrid Complex of Photosystem I and [NiFe]-Hydrogenase

Schwarze, A., Kopczak, M. J., Rögner, M., & Lenz, O. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.02700-09 · Cited by 47

Autotrophic Production of Stable-Isotope-Labeled Arginine in Ralstonia eutropha Strain H16

Lütte, S., Pohlmann, A., ZAYCHIKOV, E. F., Schwartz, E., Becher, J. R., Heumann, H., & Friedrich, B. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.01972-12 · Cited by 47

Global changes in the proteome of Cupriavidus necator H16 during poly-(3-hydroxybutyrate) synthesis from various biodiesel by-product substrates

Sharma, P., Fu, J., Spicer, V., Krokhin, O. V., Çiçek, N., Sparling, R., & Levin, D. B. (2016) · AMB Express · doi:10.1186/s13568-016-0206-z · Cited by 47

A warm welcome for alternative CO 2 fixation pathways in microbial biotechnology

Claassens, N. J. (2016) · Microbial Biotechnology · doi:10.1111/1751-7915.12456 · Cited by 47

Engineering the biological conversion of formate into crotonate in Cupriavidus necator

Collas, F., Dronsella, B., Kubis, A., Schann, K., Binder, S., Arto, N., Claassens, N. J., Kensy, F., & Orsi, E. (2023) · Metabolic Engineering · doi:10.1016/j.ymben.2023.06.015 · Cited by 46

Metabolic engineering for isopropanol production by an engineered cyanobacterium, Synechococcus elongatus PCC 7942, under photosynthetic conditions

Hirokawa, Y., Dempo, Y., Fukusaki, E., & Hanai, T. (2016) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2016.07.005 · Cited by 45

The Use of Palm Oil-Based Waste Cooking Oil to Enhance the Production of Polyhydroxybutyrate [P(3HB)] by Cupriavidus necator H16 Strain

Kamilah, H., Al-Gheethi, A. A. S., Yang, T. A., & Sudesh, K. (2018) · Arabian Journal for Science and Engineering · doi:10.1007/s13369-018-3118-1 · Cited by 45

TrfA dimers play a role in copy-number control of RK2 replication1Published in conjunction with A Wisconsin Gathering Honoring Waclaw Szybalski on the occasion of his 75th year and 20years of Editorship-in-Chief of Gene, 10–11 August 1997, University of Wisconsin, Madison, WI, USA.1

Toukdarian, A. E., & Helinski, D. R. (1998) · Gene · doi:10.1016/s0378-1119(98)00370-9 · Cited by 44

High-Efficiency Production of Bioplastics from Biodegradable Organic Solids

Du, G., Chen, L. X. L., & Yu, J. (2003) · Journal of Polymers and the Environment · doi:10.1023/b:jooe.0000010054.58019.21 · Cited by 44

Exploiting mixtures of H2, CO2, and O2 for improved production of methacrylate precursor 2-hydroxyisobutyric acid by engineered Cupriavidus necator strains

Przybylski, D., Rohwerder, T., Dilßner, C., Maskow, T., Harms, H., & Müller, R. (2014) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-014-6266-6 · Cited by 44

Lactose- and galactose-utilizing strains of poly(hydroxyalkanoic acid)-accumulating Alcaligenes eutrophus and Pseudomonas saccharophila obtained by recombinant DNA technology

Pries, A., Steinb�chel, A., & Schlegel, H. (1990) · Applied Microbiology and Biotechnology · doi:10.1007/bf00176656 · Cited by 43

Date seed characterisation, substrate extraction and process modelling for the production of polyhydroxybutyrate by Cupriavidus necator

Yousuf, R. G., & Winterburn, J. B. (2016) · Bioresource Technology · doi:10.1016/j.biortech.2016.09.107 · Cited by 43

Trehalose production by Cupriavidus necator from CO2 and hydrogen gas

Löwe, H., Beentjes, M., Pflüger‐Grau, K., & Kremling, A. (2020) · Bioresource Technology · doi:10.1016/j.biortech.2020.124169 · Cited by 43

Biosensor-informed engineering of Cupriavidus necator H16 for autotrophic D-mannitol production

Hanko, E. K. R., Sherlock, G., Minton, N. P., & Malys, N. (2022) · Metabolic Engineering · doi:10.1016/j.ymben.2022.02.003 · Cited by 42

Identification and molecular characterization of the acetyl coenzyme A synthetase gene (acoE) of Alcaligenes eutrophus

Priefert, H., & Steinbüchel, A. (1992) · Journal of Bacteriology · doi:10.1128/jb.174.20.6590-6599.1992 · Cited by 41

A Synthetic Anhydrotetracycline-Controllable Gene Expression System in Ralstonia eutropha H16

Li, H., & Liao, J. C. (2014) · ACS Synthetic Biology · doi:10.1021/sb4001189 · Cited by 41

Improved artificial pathway for biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) with high C6-monomer composition from fructose in Ralstonia eutropha

Insomphun, C., Xie, H., Mifune, J., Kawashima, Y., Orita, I., Nakamura, S., & Fukui, T. (2014) · Metabolic Engineering · doi:10.1016/j.ymben.2014.10.006 · Cited by 40

Reaction engineering studies for the production of 2-hydroxyisobutyric acid with recombinant Cupriavidus necator H 16

Hoefel, T., Wittmann, E., Reinecke, L., & Weuster‐Botz, D. (2010) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-010-2739-4 · Cited by 40

An Efficient Transformation Method for the Bioplastic‐Producing “Knallgas” Bacterium Ralstonia eutropha H16

Tee, K. L., Grinham, J., Othusitse, A. M., González‐Villanueva, M., Johnson, A. O., & Wong, T. S. (2017) · Biotechnology Journal · doi:10.1002/biot.201700081 · Cited by 40

Metabolic flux modeling of detoxification of acetic acid by Ralstonia eutropha at slightly alkaline pH levels

Yu, J. Z., & Wang, J. (2001) · Biotechnology and Bioengineering · doi:10.1002/bit.1080 · Cited by 39

Biosynthesis of polyhydroxyalkanoates from sugarcane molasses by recombinant Ralstonia eutropha strains

Jo, S. Y., Sohn, Y. J., Park, S. Y., Son, J., Yoo, J. I., Baritugo, K., David, Y., Kang, K. H., Kim, H., Choi, J.-I., et al. (2021) · Korean Journal of Chemical Engineering · doi:10.1007/s11814-021-0783-7 · Cited by 39

Analysis of 4-Phosphopantetheinylation of Polyhydroxybutyrate Synthase from Ralstonia eutropha : Generation of β-Alanine Auxotrophic Tn 5 Mutants and Cloning of the panD Gene Region

Hoppensack, A., Rehm, B. H. A., & Steinbüchel, A. (1999) · Journal of Bacteriology · doi:10.1128/jb.181.5.1429-1435.1999 · Cited by 38

Manipulation of Ralstonia eutropha Carbon Storage Pathways to Produce Useful Bio-Based Products

Brigham, C. J., Zhila, N. O., Shishatskaya, E. I., Volova, T. G., & Sinskey, A. J. (2012) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-007-5055-5_17 · Cited by 38

Expanding the genetic tool box for Cupriavidus necator by a stabilized L-rhamnose inducible plasmid system

Sydow, A., Pannek, A., Krieg, T., Huth, I., Guillouet, S., & Holtmann, D. (2017) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2017.10.002 · Cited by 38

Adaptive Laboratory Evolution of Cupriavidus necator H16 for Carbon Co-Utilization with Glycerol

González‐Villanueva, M., Galaiya, H., Staniland, P., Staniland, J., Savill, I., Wong, T. S., & Tee, K. L. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225737 · Cited by 38

An analysis of the changes in soluble hydrogenase and global gene expression in Cupriavidus necator (Ralstonia eutropha) H16 grown in heterotrophic diauxic batch culture

Jugder, B., Chen, Z., Ping, D. T. T., Lebhar, H., Welch, J. H., & Marquis, C. P. (2015) · Microbial Cell Factories · doi:10.1186/s12934-015-0226-4 · Cited by 37

Metabolic circuits and gene regulators in polyhydroxyalkanoate producing organisms: Intervention strategies for enhanced production

Sindhu, R., Madhavan, A., Arun, K. B., Pugazhendhi, A., Rajasekharan, R., Awasthi, M. K., Sirohi, R., Tarafdar, A., Pandey, A., & Binod, P. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.124791 · Cited by 36

Production of recombinant proteins using multiple‐copy gene integration in high‐cell‐density fermentations of Ralstonia eutropha

Srinivasan, S., Barnard, G. C., & Gerngross, T. U. (2003) · Biotechnology and Bioengineering · doi:10.1002/bit.10756 · Cited by 35

Novel Aldo-Keto Reductases for the Biocatalytic Conversion of 3-Hydroxybutanal to 1,3-Butanediol: Structural and Biochemical Studies

Kim, T., Flick, R., Brunzelle, J. S., Singer, A. U., Evdokimova, E., Brown, G., Joo, J. C., Minasov, G., Anderson, W. F., Mahadevan, R., et al. (2017) · Applied and Environmental Microbiology · doi:10.1128/aem.03172-16 · Cited by 35

Limitations in converting waste gases to fuels and chemicals

Emerson, D. F., & Stephanopoulos, G. N. (2019) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2019.02.004 · Cited by 35

Plasmid segregation without partition

Guynet, C., & de la Cruz, F. (2011) · Mobile Genetic Elements · doi:10.4161/mge.1.3.18229 · Cited by 34

Comparative study of promoters for the production of polyhydroxyalkanoates in recombinant strains of Wautersia eutropha

Delamarre, S. C., & Batt, C. A. (2005) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-005-0217-1 · Cited by 34

Design of inducible expression vectors for improved protein production in Ralstonia eutropha H16 derived host strains

Gruber, S., Schwendenwein, D., Magomedova, Z. M., Thaler, E., Hagen, J., Schwab, H., & Heidinger, P. (2016) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2016.04.026 · Cited by 34

First time β-farnesene production by the versatile bacterium Cupriavidus necator

Milker, S., & Holtmann, D. (2021) · Microbial Cell Factories · doi:10.1186/s12934-021-01562-x · Cited by 34

Monoterpenoid biosynthesis by engineered microbes

Liu, Y., Ma, X., Liang, H., Stephanopoulos, G., & Zhou, K. (2021) · Journal of Industrial Microbiology and Biotechnology · doi:10.1093/jimb/kuab065 · Cited by 34

Metabolite profiles of polyhydroxyalkanoate-producing Ralstonia eutropha H16

Fukui, T., Chou, K., Harada, K., Orita, I., Nakayama, Y., Bamba, T., Nakamura, S., & Fukusaki, E. (2013) · Metabolomics · doi:10.1007/s11306-013-0567-0 · Cited by 33

Complete Genome Sequence of 3-Chlorobenzoate-Degrading Bacterium Cupriavidus necator NH9 and Reclassification of the Strains of the Genera Cupriavidus and Ralstonia Based on Phylogenetic and Whole-Genome Sequence Analyses

Moriuchi, R., Dohra, H., Kanesaki, Y., & Ogawa, N. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00133 · Cited by 33

Growth of the facultative chemolithoautotroph Ralstonia eutropha on organic waste materials: growth characteristics, redox regulation and hydrogenase activity

Poladyan, A. A., Blbulyan, S., Sahakyan, M., Lenz, O., & Trchоunian, A. (2019) · Microbial Cell Factories · doi:10.1186/s12934-019-1251-5 · Cited by 33

Proteomic examination of Ralstonia eutropha in cellular responses to formic acid

Lee, S., Li, Q. X., & Yu, J. (2006) · PROTEOMICS · doi:10.1002/pmic.200500824 · Cited by 32

Rearrangement of Coenzyme A-Acylated Carbon Chain Enables Synthesis of Isobutanol via a Novel Pathway in Ralstonia eutropha

Black, W. B., Zhang, L., Kamoku, C., Liao, J. C., & Li, H. (2018) · ACS Synthetic Biology · doi:10.1021/acssynbio.7b00409 · Cited by 32

Aromatic hydroxylation of substituted benzenes by an unspecific peroxygenase from Aspergillus brasiliensis

Schmitz, F., Koschorreck, K., Hollmann, F., & Urlacher, V. B. (2023) · Reaction Chemistry & Engineering · doi:10.1039/d3re00209h · Cited by 32

Characterization of alcohol dehydrogenase genes of derepressible wild-type Alcaligenes eutrophus H16 and constitutive mutants

Jendrossek, D., Krüger, N., & Steinbüchel, A. (1990) · Journal of Bacteriology · doi:10.1128/jb.172.9.4844-4851.1990 · Cited by 31

Use of the valine biosynthetic pathway to convert glucose into isobutanol

Savrasova, E. A., Kivero, A. D., Shakulov, R. S., & Stoynova, N. V. (2010) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-010-0907-2 · Cited by 31

CO synthesized from the central one-carbon pool as source for the iron carbonyl in O 2 -tolerant [NiFe]-hydrogenase

Bürstel, I., Siebert, E., Frielingsdorf, S., Zebger, I., Friedrich, B., & Lenz, O. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1614656113 · Cited by 31

Complete Genome Sequence of Cupriavidus necator H16 (DSM 428)

Little, G. T., Ehsaan, M., Arenas-López, C., Jawed, K., Winzer, K., Kovács, K., & Minton, N. P. (2019) · Microbiology Resource Announcements · doi:10.1128/mra.00814-19 · Cited by 31

Development of a gene knockout system for Ralstonia eutropha H16 based on the broad-host-range vector expressing a mobile group II intron

Park, J. M., Jang, Y., Kim, T. Y., & Lee, S. Y. (2010) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2010.02041.x · Cited by 30

Biosynthesis of polyhydroxyalkanoates (PHAs) with continuous feeding of mixed organic acids as carbon sources by Ralstonia eutropha

Yan, Q., Du, G., & Chen, J. (2003) · Process Biochemistry · doi:10.1016/s0032-9592(03)00127-4 · Cited by 30

CbbR and RegA regulate cbb operon transcription in Ralstonia eutropha H16

Gruber, S., Schwab, H., & Heidinger, P. (2017) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2017.07.005 · Cited by 30

Trehalose and its Diverse Biological Potential

Sharma, E., Shruti, P. S., Singh, S., Singh, T., Kaur, P., Jodha, B., Srivastava, Y., Munshi, A., & Singh, S. (2023) · Current Protein and Peptide Science · doi:10.2174/1389203724666230606154719 · Cited by 30

Engineering a Rhodopsin-Based Photo-Electrosynthetic System in Bacteria for CO2 Fixation

Davison, P. A., Tu, W., Xu, J., Valle, S. D., Thompson, I. P., Hunter, C. N., & Huang, W. E. (2022) · ACS Synthetic Biology · doi:10.1021/acssynbio.2c00397 · Cited by 29

Metabolic engineering of Cupriavidus necator H16 for heterotrophic and autotrophic production of 3-hydroxypropionic acid

Salinas, A., McGregor, C., Irorere, V. U., Arenas-López, C., Bommareddy, R. R., Winzer, K., Minton, N. P., & Kovács, K. (2022) · Metabolic Engineering · doi:10.1016/j.ymben.2022.10.014 · Cited by 29

Plasmid Strategies for Broad-Host-Range Replication in Gram-Negative Bacteria

Toukdarian, A. E. (2014) · ASM Press eBooks · doi:10.1128/9781555817732.ch11 · Cited by 28

Gram‐scale production of the sesquiterpene α‐humulene with Cupriavidus necator

Milker, S., Sydow, A., Torres‐Monroy, I., Jach, G., Faust, F., Kranz, L., Tkatschuk, L., & Holtmann, D. (2021) · Biotechnology and Bioengineering · doi:10.1002/bit.27788 · Cited by 28

Biosynthesis of Poly(3HB-co-3HP) with Variable Monomer Composition in Recombinant Cupriavidus necator H16

McGregor, C., Minton, N. P., & Kovács, K. (2021) · ACS Synthetic Biology · doi:10.1021/acssynbio.1c00283 · Cited by 28

Advances in glucosamine production from waste biomass and microbial fermentation technology and its applications

Ahuja, V., Bhatt, A. K., Sharma, V., Rathour, R. K., Rana, N., Bhatia, R. K., Varjani, S., Kumar, M., Magdouli, S., Yung-HunYang, et al. (2021) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-021-01968-y · Cited by 28

Development of an autotrophic fermentation technique for the production of fatty acids using an engineered Ralstonia eutropha cell factory

Li, Z., Xiong, B., Liu, L., Li, S., Xin, X., Li, Z., Zhang, X., & Bi, C. (2019) · Journal of Industrial Microbiology & Biotechnology · doi:10.1007/s10295-019-02156-8 · Cited by 28

Thermodynamic limitations of PHB production from formate and fructose in Cupriavidus necator

Janasch, M., Crang, N., Asplund‐Samuelsson, J., Sporre, E., Bruch, M., Gynnå, A. H., Jahn, M., & Hudson, E. P. (2022) · Metabolic Engineering · doi:10.1016/j.ymben.2022.08.005 · Cited by 28

Heterotrophic and autotrophic production of L-isoleucine and L-valine by engineered Cupriavidus necator H16

Wang, L., Yao, J., Tu, T., Yao, B., & Zhang, J. (2024) · Bioresource Technology · doi:10.1016/j.biortech.2024.130538 · Cited by 28

Effects of Homologous Phosphoenolpyruvate-Carbohydrate Phosphotransferase System Proteins on Carbohydrate Uptake and Poly(3-Hydroxybutyrate) Accumulation in Ralstonia eutropha H16

Kaddor, C., & Steinbüchel, A. (2011) · Applied and Environmental Microbiology · doi:10.1128/aem.00218-11 · Cited by 27

Solvent production by engineered Ralstonia eutropha: channeling carbon to biofuel

Chakravarty, J., & Brigham, C. J. (2018) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-018-9026-1 · Cited by 27

Automatic Control of Chemolithotrophic Cultivation of Cupriavidus necator: Optimization of Oxygen Supply for Enhanced Bioplastic Production

Lambauer, V., Permann, A., Petrášek, Z., Subotić, V., Hochenauer, C., Kratzer, R., & Reichhartinger, M. (2023) · Fermentation · doi:10.3390/fermentation9070619 · Cited by 27

Efficient biological conversion of carbon monoxide (CO) to carbon dioxide (CO 2 ) and for utilization in bioplastic production by Ralstonia eutropha through the display of an enzyme complex on the cell surface

Hyeon, J. E., Kim, S. W., Park, C., & Han, S. O. (2015) · Chemical Communications · doi:10.1039/c5cc00832h · Cited by 26

The myo-inositol-1-phosphate synthase gene is essential in Trypanosoma brucei

Martin, K. L., & Smith, T. (2005) · Biochemical Society Transactions · doi:10.1042/bst0330983 · Cited by 26

Expanding the synthetic biology toolbox of Cupriavidus necator for establishing fatty acid production

Mishra, S., Perkovich, P. M., Mitchell, W. P., Venkataraman, M., & Pfleger, B. F. (2024) · Journal of Industrial Microbiology & Biotechnology · doi:10.1093/jimb/kuae008 · Cited by 26

Rapid selection of glucose-utilizing variants of the polyhydroxyalkanoate producer Ralstonia eutropha H16 by incubation with high substrate levels

Franz, A., Rehner, R., Kienle, A., & Grammel, H. (2011) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.2011.03171.x · Cited by 25

Microbial Transformations of Prosulfuron

Kulowski, K., Zirbes, E. L., Thede, B. M., & Rosazza, J. P. N. (1997) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf9604495 · Cited by 25

A physical map of the megaplasmid pHG1, one of three genomic replicons in Ralstonia eutropha H16

Schwartz, E., & Friedrich, B. (2001) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2001.tb10759.x · Cited by 25

Enhanced production of polyhydroxybutyrate from syngas by using nanoscaled cellulose particles with a syngas-converting enzyme complex immobilized on Ralstonia eutropha

Shin, S. K., Ko, Y. J., Jeong, D., Lee, M.-E., You, S. K., Hyeon, J. E., & Han, S. O. (2020) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2020.124903 · Cited by 25

Establishing CRISPRi for Programmable Gene Repression and Genome Evolution in Cupriavidus necator

Wang, Z., Pan, H., Ni, S., Li, Z., & Lian, J. (2024) · ACS Synthetic Biology · doi:10.1021/acssynbio.3c00664 · Cited by 25

Regulation of Replication and Maintenance Functions of Broad Host-Range Plasmid RK2

Thomas, C. M., Smith, C., Shingler, V., Cross, M. A., Hussain, A., & Pinkney, M. (1985) · Springer eBooks · doi:10.1007/978-1-4613-2447-8_21 · Cited by 24

Expression of the Escherichia coli pfkA gene in Alcaligenes eutrophus and in other gram-negative bacteria

Steinbüchel, A. (1986) · Journal of Bacteriology · doi:10.1128/jb.166.1.319-327.1986 · Cited by 24

The reliance of glycerol utilization by Cupriavidus necator on CO2 fixation and improved glycerol catabolism

Strittmatter, C. S., Eggers, J., Biesgen, V., Pauels, I., Becker, F., & Steinbüchel, A. (2022) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-022-11842-0 · Cited by 24

Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering

Coleman, T., Lee, J. H. Z., Kirk, A. M., Doherty, D. Z., Podgorski, M. N., Pinidiya, D. K., Bruning, J. B., Voss, J. J. D., Krenske, E. H., & Bell, S. G. (2022) · Chemistry - A European Journal · doi:10.1002/chem.202201895 · Cited by 24

Aerobic phenol degradation using native bacterial consortium via ortho–and meta–cleavage pathways

Shebl, S., Ghareeb, D. A., Ali, S. M., Ghanem, N. B. E. D., & Olama, Z. A. (2024) · Frontiers in Microbiology · doi:10.3389/fmicb.2024.1400033 · Cited by 24

In vitro induction of lipo-chitooligosaccharide production in Bradyrhizobium japonicum cultures by root extracts from non-leguminous plants

Lian, B., Souleimanov, A., Zhou, X., & Smith, D. L. (2002) · Microbiological Research · doi:10.1078/0944-5013-00145 · Cited by 23

Production of acetoin from renewable resources under heterotrophic and mixotrophic conditions

Härrer, D., Windhorst, C., Böhner, N., Ducassou, J. N., Couté, Y., & Gescher, J. (2021) · Bioresource Technology · doi:10.1016/j.biortech.2021.124866 · Cited by 23

Improving carbon monoxide tolerance of Cupriavidus necator H16 through adaptive laboratory evolution

Wickham-Smith, C., Malys, N., & Winzer, K. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1178536 · Cited by 23

Isopropanol production with reutilization of glucose-derived CO2 by engineered Ralstonia eutropha

Subagyo, D. C. H., Shimizu, R., Orita, I., & Fukui, T. (2021) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2021.08.004 · Cited by 22

Engineering Cupriavidus necator H16 for heterotrophic and autotrophic production of myo-inositol

Wang, X., Wang, K., Wang, L., Luo, H., Wang, Y., Wang, Y., Tu, T., Qin, X., Su, X., Bai, Y., et al. (2022) · Bioresource Technology · doi:10.1016/j.biortech.2022.128321 · Cited by 22

Establishment of an alternative phosphoketolase-dependent pathway for fructose catabolism in Ralstonia eutropha H16

Fleige, C., Kroll, J., & Steinbüchel, A. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3284-5 · Cited by 21

Biosynthesis of polyhydroxyalkanoates from vegetable oil under the co-expression of fadE and phaJ genes in Cupriavidus necator

Flores-Sánchez, A., Rathinasabapathy, A., López-Cuellar, M. D. R., Vergara‐Porras, B., & Pérez‐Guevara, F. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.07.275 · Cited by 21

CO2-based production of phytase from highly stable expression plasmids in Cupriavidus necator H16

Arhar, S., Rauter, T., Stolterfoht, H., Lambauer, V., Kratzer, R., Winkler, M., Karava, M., Kourist, R., & Emmerstorfer‐Augustin, A. (2024) · Microbial Cell Factories · doi:10.1186/s12934-023-02280-2 · Cited by 21

Isolation of Glucose Utilizing Mutant of Alcaligenes eutrophus, its Substrate Selectivity, and Accumulation of Poly-β-hydroxybutyrate

Kim, H., Park, J. S., Shin, H., & Lee, Y. (1995) · The Journal of Microbiology · Cited by 21

Utilization of Dielectrophoresis for the Quantification of Rare Earth Elements Adsorbed on Cupriavidus necator

Adekanmbi, E. O., Giduthuri, A. T., Waymire, S., & Srivastava, S. K. (2019) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.9b03878 · Cited by 20

Insights into the Degradation of Medium-Chain-Length Dicarboxylic Acids in Cupriavidus necator H16 Reveal β-Oxidation Differences between Dicarboxylic Acids and Fatty Acids

Strittmatter, C. S., Eggers, J., Biesgen, V., Hengsbach, J., Sakatoku, A., Albrecht, D., Riedel, K., & Steinbüchel, A. (2021) · Applied and Environmental Microbiology · doi:10.1128/aem.01873-21 · Cited by 20

Alka(e)ne synthesis in Cupriavidus necator boosted by the expression of endogenous and heterologous ferredoxin–ferredoxin reductase systems

Crépin, L., Barthe, M., Leray, F., & Guillouet, S. (2018) · Biotechnology and Bioengineering · doi:10.1002/bit.26805 · Cited by 19

pCAT vectors overcome inefficient electroporation of Cupriavidus necator H16

Azubuike, C. C., Gatehouse, A. M. R., & Howard, T. P. (2021) · New Biotechnology · doi:10.1016/j.nbt.2021.07.003 · Cited by 19

Optimization of chemico-physical transformation methods for various bacterial species using diverse chemical compounds and nanomaterials

Ren, J., Na, D., & Yoo, S. M. (2018) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2018.11.003 · Cited by 18

Construction of Cupriavidus necator displayed with superoxide dismutases for enhanced growth in bioelectrochemical systems

Chen, K., Ma, C., Cheng, X., Wang, Y., Guo, K., Wu, R., & Zhu, Z. (2023) · Bioresources and Bioprocessing · doi:10.1186/s40643-023-00655-2 · Cited by 18

Implications of various phosphoenolpyruvate-carbohydrate phosphotransferase system mutations on glycerol utilization and poly(3-hydroxybutyrate) accumulation in Ralstonia eutropha H16

Kaddor, C., & Steinbüchel, A. (2011) · AMB Express · doi:10.1186/2191-0855-1-16 · Cited by 17

Construction and use of a Cupriavidus necator H16 soluble hydrogenase promoter (P SH ) fusion to gfp (green fluorescent protein)

Jugder, B., Welch, J. H., Braidy, N., & Marquis, C. P. (2016) · PeerJ · doi:10.7717/peerj.2269 · Cited by 17

Metabolic pathway analysis for in silico design of efficient autotrophic production of advanced biofuels

Unrean, P., Tee, K. L., & Wong, T. S. (2019) · Bioresources and Bioprocessing · doi:10.1186/s40643-019-0282-4 · Cited by 17

Production of N-acetylglucosamine from carbon dioxide by engineering Cupriavidus necator H16

Wang, X., Chang, F., Wang, T., Luo, H., Su, X., Tu, T., Wang, Y., Bai, Y., Qin, X., Zhang, H., et al. (2023) · Bioresource Technology · doi:10.1016/j.biortech.2023.129024 · Cited by 17

From Rags to Riches: Exploiting the Calvin‐Benson‐Bassham Cycle for Biomanufacturing

Federici, F., Orsi, E., & Nikel, P. I. (2023) · ChemCatChem · doi:10.1002/cctc.202300746 · Cited by 17

Carbon dioxide valorization into resveratrol via lithoautotrophic fermentation using engineered Cupriavidus necator H16

Jang, Y., Lee, Y. J., Gong, G., Lee, S., Um, Y., Kim, K. H., & Ko, J. K. (2024) · Microbial Cell Factories · doi:10.1186/s12934-024-02398-x · Cited by 17

High‐cell‐density fed‐batch strategy to manufacture tailor‐made P( HB‐ co ‐HHx ) by engineered Ralstonia eutropha at laboratory scale and pilot scale

Thiele, I., Santolin, L., Detels, S., Osele, R., Neubauer, P. B., & Riedel, S. L. (2024) · Microbial Biotechnology · doi:10.1111/1751-7915.14488 · Cited by 17

Molecular Mechanisms of Transcription Initiation at gal Promoters and their Multi-Level Regulation by GalR, CRP and DNA Loop

Lewis, D. E. A., & Adhya, S. L. (2015) · Biomolecules · doi:10.3390/biom5042782 · Cited by 16

Production of Bio-Based Isoprene by the Mevalonate Pathway Cassette in Ralstonia eutropha

Lee, H.-W., Park, J., Lee, H., Choi, W., Seo, S.-H., Anggraini, I. D., Choi, E., & Lee, H.-W. (2019) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.1909.09002 · Cited by 16

Stable Platform for Mevalonate Bioproduction from CO 2

Garavaglia, M., McGregor, C., Bommareddy, R. R., Irorere, V. U., Arenas, C., Robazza, A., Minton, N. P., & Kovács, K. (2024) · ACS Sustainable Chemistry & Engineering · doi:10.1021/acssuschemeng.4c03561 · Cited by 16

The malate dehydrogenase ofRalstonia eutrophaand functionality of the C3/C4metabolism in a Tn5-inducedmdhmutant

Brämer, C. O., & Steinbüchel, A. (2002) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2002.tb11260.x · Cited by 15

Occurrence of deletion plasmids at high rates after conjugative transfer of the plasmids RP4 and RK2 from Escherichia coli to Alcaligenes eutrophus H16

Schwab, H., Saurugger, P. N., & Lafferty, R. M. (1983) · Archives of Microbiology · doi:10.1007/bf00404789 · Cited by 15

Physiological conditions conducive to high cell density and high cyanophycin content in Ralstonia eutropha strain H16 possessing a KDPG aldolase gene-dependent addiction system

Lin, K., Elbahloul, Y., & Steinbüchel, A. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3685-5 · Cited by 15

Single and Dual Metal Oxides as Promising Supports for Carbon Monoxide Removal from an Actual Syngas: The Crucial Role of Support on the Selectivity of the Au–Cu System

Cifuentes, B., Bustamante, F., & Cobo, M. I. (2019) · Catalysts · doi:10.3390/catal9100852 · Cited by 15

Tn5 transposition: a molecular tool for studying protein structure–function

Reznikoff, W. S. (2006) · Biochemical Society Transactions · doi:10.1042/bst0340320 · Cited by 15

Impact of each individual component of the mutated PTSNag on glucose uptake and phosphorylation in Ralstonia eutropha G+1

Raberg, M., Kaddor, C., Kusian, B., Stahlhut, G., Budinova, R., Kolev, N. Z., Bowien, B., & Steinbüchel, A. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-3911-9 · Cited by 14

Experimental evolution and gene knockout studies reveal AcrA-mediated isobutanol tolerance in Ralstonia eutropha

Bernardi, A. C., Gai, C. S., Lu, J., Sinskey, A. J., & Brigham, C. J. (2016) · Journal of Bioscience and Bioengineering · doi:10.1016/j.jbiosc.2015.12.015 · Cited by 14

Elevated poly(3-hydroxybutyrate) synthesis in mutants of Ralstonia eutropha H16 defective in lipopolysaccharide biosynthesis

Brandt, U., Raberg, M., Voigt, B., Hecker, M., & Steinbüchel, A. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-3909-3 · Cited by 13

A novel gene expression system for Ralstonia eutropha based on the T7 promoter

Hu, M., Xiong, B., Li, Z., Liu, L., Li, S., Zhang, C., Zhang, X., & Bi, C. (2020) · BMC Microbiology · doi:10.1186/s12866-020-01812-9 · Cited by 13

Tailored polyhydroxyalkanoate production from renewable non-fatty acid carbon sources using engineered Cupriavidus necator H16

Park, S., Roh, S., Yoo, J. H., Ahn, J. H., Gong, G., Lee, S., Um, Y., Han, S. O., & Ko, J. K. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.130360 · Cited by 13

Activation of Ethanol Production by Combination of Recombinant Ralstonia eutropha and Electrochemical Reducing Power

Jeon, B. Y., Yi, J. Y., Jung, I. L., & Park, D. H. (2013) · Advances in Microbiology · doi:10.4236/aim.2013.31006 · Cited by 12

A new shuttle vector for gene expression in biopolymer-producing Ralstonia eutropha

Solaiman, D. K. Y., Swingle, B. M., & Ashby, R. D. (2010) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2010.04.010 · Cited by 12

Application of dielectrophoresis towards characterization of rare earth elements biosorption by Cupriavidus necator

Adekanmbi, E. O., Giduthuri, A. T., Carv, B. A. C., Counts, J. R., Moberly, J. G., & Srivastava, S. K. (2020) · Analytica Chimica Acta · doi:10.1016/j.aca.2020.07.042 · Cited by 12

Fermentative α-Humulene Production from Homogenized Grass Clippings as a Growth Medium

Langsdorf, A., Drommershausen, A., Volkmar, M., Ulber, R., & Holtmann, D. (2022) · Molecules · doi:10.3390/molecules27248684 · Cited by 12

Ability of Cupriavidus necator H16 to resist, bioremove, and accumulate some hazardous metal ions in water

Akkurt, Ş., Uçkun, A. A., VARINCA, K. B., & Uçkun, M. (2023) · Water Science & Technology · doi:10.2166/wst.2023.188 · Cited by 12

Construction of microbial platform chassis for CO2 utilisation

Valle, S. D., Tu, W., & Huang, W. E. (2023) · Current Opinion in Systems Biology · doi:10.1016/j.coisb.2023.100489 · Cited by 12

Investigations on three genes in Ralstonia eutropha H16 encoding putative cyanophycin metabolizing enzymes

Adames, K., Euting, K., Bröker, A., & Steinbüchel, A. (2012) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-012-4599-6 · Cited by 11

Development of a plasmid-based, tunable, tolC -derived expression system for application in Cupriavidus necator H16

Aboulnaga, E., Zou, H., Selmer, T., & Xian, M. (2018) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2018.03.007 · Cited by 11

Production of branched-chain alcohols by recombinant Ralstonia eutropha in fed-batch cultivation

Fei, Q., Brigham, C. J., Lu, J., Fu, R., & Sinskey, A. J. (2013) · Biomass and Bioenergy · doi:10.1016/j.biombioe.2013.05.009 · Cited by 10

Coping with Anoxia: A Comprehensive Proteomic and Transcriptomic Survey of Denitrification

Kohlmann, Y., Pohlmann, A., Schwartz, E., Zühlke, D., Otto, A., Albrecht, D., Grimmler, C., Ehrenreich, A., Voigt, B., Becher, D., et al. (2014) · Journal of Proteome Research · doi:10.1021/pr500491r · Cited by 10

Medium-Chain-Length Fatty Acid Catabolism in Cupriavidus necator H16: Transcriptome Sequencing Reveals Differences from Long-Chain-Length Fatty Acid β-Oxidation and Involvement of Several Homologous Genes

Strittmatter, C. S., Poehlein, A., Himmelbach, A., Daniel, R., & Steinbüchel, A. (2022) · Applied and Environmental Microbiology · doi:10.1128/aem.01428-22 · Cited by 10

Production of succinate with two CO2 fixation reactions from fatty acids in Cupriavidus necator H16

Li, L., Zhou, X., Gao, Z., Xiong, P., & Liu, X. (2024) · Microbial Cell Factories · doi:10.1186/s12934-024-02470-6 · Cited by 9

Characterization of 2-phenanthroate:CoA ligase from the sulfate-reducing, phenanthrene-degrading enrichment culture TRIP

Kaplieva-Dudek, I., Samak, N. A., Bormann, J., Kaschani, F., Kaiser, M., & Meckenstock, R. U. (2024) · Applied and Environmental Microbiology · doi:10.1128/aem.01296-24 · Cited by 9

[Engineering of a D-xylose metabolic pathway in eutropha W50].

Liu, K., Liu, G., Zhang, Y., Ding, J., & Weng, W. (2014) · PubMed · Cited by 6

Precision medicine in neurosurgery: The evolving role of theranostics

Patel, D., Nguyen, A., Fleeting, C. R., Patel, A. B., Mumtaz, M., & Lucke-Wold, B. P. (2023) · INNOSC Theranostics and Pharmacological Sciences · doi:10.36922/itps.417 · Cited by 5

The potential application of carbazole-degrading bacteria for dioxin bioremediation

Dinh, M. T. N., Nguyen, V. T. T., & Nguyen, L. T. H. (2023) · Bioresources and Bioprocessing · doi:10.1186/s40643-023-00680-1 · Cited by 5

METABOLIC PATHWAYS | Release of Energy (Anaerobic)

Elbeshbishy, E. (2014) · Encyclopedia of Food Microbiology · doi:10.1016/b978-0-12-384730-0.00198-1 · Cited by 5

Langfristiges organotrophes Wachstum von Hydrogenomonas H 16 im Chemostaten

K�nig, C., & Schlegel, H. G. (1968) · Archives of Microbiology · doi:10.1007/bf00407052 · Cited by 4

Co-expression of an isopropanol synthetic operon and eGFP to monitor the robustness of Cupriavidus necator during isopropanol production

Boy, C., Lesage, J., Alfenore, S., Guillouet, S., & Gorret, N. (2022) · Enzyme and Microbial Technology · doi:10.1016/j.enzmictec.2022.110114 · Cited by 4

High‐cell‐density fed‐batch strategy to manufacture tailor‐made P(HB‐co‐HHx) by engineered Ralstonia eutropha at laboratory scale and pilot scale

Thiele, I., Santolin, L., Detels, S., et al. (2024) · DepositOnce · doi:10.14279/depositonce-23493 · Cited by 2

Biofuels, E-Fuels, and Waste-Derived Fuels: Advances, Challenges, and Future Directions

Yılbaşı, Z. (2025) · Sustainability · doi:10.3390/su17136145 · Cited by 41

Recent Progress in CO 2 Conversion: An Overview of Catalytic Strategies for Sustainable Fuel and Chemical Synthesis

Zhang, A., Cai, Y., Guo, L., Wang, C., Wa, Q., Xu, Y., Zhou, J. H., Fan, H., Li, Z., Long, X., et al. (2025) · SmartMat · doi:10.1002/smm2.70058 · Cited by 36

Life cycle design of polyhydroxyalkanoates (PHA)

Sun, S., Yang, S., Qiu, Y., Ding, J., Wang, W., Wu, F., & Chen, G. (2025) · National Science Review · doi:10.1093/nsr/nwaf517 · Cited by 19

High-efficiency CO 2 fixation and single-cell protein production in Cupriavidus necator via ARTP-driven metabolic rewiring

Ma, C., Cheng, X., Wang, Y., Chen, K., Yihua, M., Lin, Y., Guo, K., & Zhu, Z. (2026) · Green Chemistry · doi:10.1039/d5gc05791d · Cited by 4

Nutritional Value and Food Safety Assessment of Single-Cell Protein Derived from Ralstonia eutropha for Food Applications

You, X., Zhang, L., Chen, L., Wang, H., Zou, H., Zhu, Z., & Zhao, G. (2026) · Foods · doi:10.3390/foods15101813 · Cited by 3

Engineering the heterotrophic carbon sources utilization range of Ralstonia eutropha H16 for applications in biotechnology

Elena, V., Raberg, M., & Steinbüchel, A. (2016) · Figshare · doi:10.6084/m9.figshare.3984417

Development of a broad-host synthetic biology toolbox for ralstonia eutropha and its application to engineering hydrocarbon biofuel production

Bi, C., Su, P., Müller, J. T., Yeh, Y.-C., Chhabra, S. R., Beller, H. R., Singer, S. W., & Hillson, N. J. (2013) · Microbial Cell Factories · doi:10.1186/1475-2859-12-107 · Cited by 126

Ralstonia eutropha H16 in progress: Applications beside PHAs and establishment as production platform by advanced genetic tools

Raberg, M., Elena, V., Lin, K., & Steinbüchel, A. (2017) · Critical Reviews in Biotechnology · doi:10.1080/07388551.2017.1369933 · Cited by 85

Biotin Synthesis in Ralstonia eutropha H16 Utilizes Pimeloyl Coenzyme A and Can Be Regulated by the Amount of Acceptor Protein

Eggers, J., Strittmatter, C. S., Küsters, K., Biller, E., & Steinbüchel, A. (2020) · Applied and Environmental Microbiology · doi:10.1128/aem.01512-20 · Cited by 5

Synthetic biology toolkit of Ralstonia eutropha (Cupriavidus necator)

Santolin, L., Riedel, S. L., & Brigham, C. J. (2024) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-024-13284-2 · Cited by 27