Informing future intensive care trials with machine learning
Open accessIntegrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
AI might help researchers design and enrol tailored patient subgroups for precise RCTs.
“Instead of using large, heterogeneous trial populations, AI might help researchers design and enrol tailored patient subgroups for precise RCTs [63, 64].”
From Implementing Artificial Intelligence in Critical Care Medicine: a consensus of 22. (2025) · cites this paper as [63]
Cites
Writing Group for the Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial (ART) Investigators, Cavalcanti, A. B., Suzumura, É. A., Laranjeira, L. N., Paisani, D. D. M., Damiani, L. P., Guimarães, H. P., Romano, E. R., Regenga, M. D. M., Taniguchi, L. N. T., et al. (2017) · JAMA · doi:10.1001/jama.2017.14171 · Cited by 1,018 · see citing works
Gattinoni, L., Pelosi, P. P., Suter, P. M., Pedoto, A. C., VERCESI, P., & Lissoni, A. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.1.9708031 · Cited by 897 · see citing works
Costa, E. L. V., Borges, J. B., Melo, A., Suárez-Sipmann, F., Toufen, C., Böhm, S. H., & Amato, M. B. P. (2009) · Intensive Care Medicine · doi:10.1007/s00134-009-1447-y · Cited by 511 · see citing works
Prescott, H. C., Calfee, C. S., Thompson, B., Angus, D. C., & Liu, V. X. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201512-2544cp · Cited by 323 · see citing works
Emotion, cognitive load and learning outcomes during simulation training
Fraser, K. L., Ma, I. W. Y., Teteris, E., Baxter, H., Wright, B. J., & McLaughlin, K. (2012) · Medical Education · doi:10.1111/j.1365-2923.2012.04355.x · Cited by 312 · see citing works
Alveolar Pressure, Pulmonary Venous Pressure, and the Vascular Waterfall
Permutt, S., Bromberger-Barnea, B., & Bane, H. N. (2009) · Medicina Thoracalis · doi:10.1159/000192224 · Cited by 291 · see citing works
Iwashyna, T. J., Burke, J. F., Sussman, J. B., Prescott, H. C., Hayward, R. A., & Angus, D. C. (2015) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201411-2125cp · Cited by 276 · see citing works
Ventilatory management of acute respiratory distress syndrome: A consensus of two.
Marini, J. J., & Gattinoni, L. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000104946.66723.a8 · Cited by 168 · see citing works
Six subphenotypes in septic shock: Latent class analysis of the PROWESS Shock study
Gårdlund, B., Dmitrieva, N., Pieper, C. F., Finfer, S. R., Marshall, J. C., & Thompson, B. (2018) · Journal of Critical Care · doi:10.1016/j.jcrc.2018.06.012 · Cited by 85 · see citing works
Zampieri, F. G., Costa, E. L. V., Iwashyna, T. J., de Carvalho, C. R. R., Damiani, L. P., Taniguchi, L. U., Amato, M. B. P., & Cavalcanti, A. B. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2019.02.026 · Cited by 76 · see citing works
Mercado, P., Maizel, J., Kontar, L., Nalos, M., Huang, S., Orde, S. R., McLean, A. S., & Slama, M. (2018) · Critical Care Medicine · doi:10.1097/ccm.0000000000003287 · Cited by 37 · see citing works
The Future of Critical Care Medicine
Vincent, J. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000001530 · Cited by 27 · see citing works
Santos, A., Lucchetta, L., García, M. I. M., Borges, J. B., Tusman, G., Hedenstierna, G., Larsson, A., & Suárez-Sipmann, F. (2016) · Critical Care Medicine · doi:10.1097/ccm.0000000000002082 · Cited by 17 · see citing works
Zigelman, C. Z., Briskin, A., & Hersch, M. (2004) · Critical Care Medicine · doi:10.1097/01.ccm.0000124854.74177.2e · Cited by 5 · see citing works
Fumagalli, J., & Berra, L. M. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2018.03.31 · Cited by 3 · see citing works
Flagged first, then by citations
1 of the 16 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Sepsis biomarkers and diagnostic tools with a focus on machine learning
Komorowski, M., Green, A., Tatham, K. C., Seymour, C. W., & Antcliffe, D. B. (2022) · EBioMedicine · doi:10.1016/j.ebiom.2022.104394 · Cited by 160 · see citing works
Self-citationImplementing Artificial Intelligence in Critical Care Medicine: a consensus of 22.
Cecconi, M., Greco, M., Shickel, B., Angus, D. C., Bailey, H., Bignami, E., Calandra, T., Celi, L. A., Einav, S., Elbers, P., et al. (2025) · Critical Care · doi:10.1186/s13054-025-05532-2 · Cited by 80 · see citing works
“Instead of using large, heterogeneous trial populations, AI might help researchers design and enrol tailored patient subgroups for precise RCTs [63, 64].”
Self-citationMachine learning in anaesthesia: reactive, proactive… predictive!
Gambús, P. L., & Jaramillo, S. (2019) · British Journal of Anaesthesia · doi:10.1016/j.bja.2019.07.009 · Cited by 32 · see citing works
Mazzinari, G., Zampieri, F. G., Ball, L., Campos, N. S., Bluth, T., Hemmes, S. N. T., Ferrando, C., Librero, J., Soro, M., Pelosi, P. P., et al. (2024) · Anesthesiology · doi:10.1097/aln.0000000000005170 · Cited by 27 · see citing works
Artificial Intelligence Applications in Space Medicine
Cheung, H. C., Louche, C. D. D., & Komorowski, M. (2023) · Aerospace Medicine and Human Performance · doi:10.3357/amhp.6178.2023 · Cited by 24 · see citing works
Self-citationAcute on chronic liver failure: prognostic models and artificial intelligence applications
Gary, P. J., Lal, A., Simonetto, D. A., Gajic, O., & de Moraes, A. G. (2023) · Hepatology Communications · doi:10.1097/hc9.0000000000000095 · Cited by 6 · see citing works
Longitudinal blood transcriptome profiling reveals immune dynamics in sepsis
Hwang, J., Cha, J. H., Ahn, S., Park, J.-H., Kim, S., Jung, M., Choi, Y., Seok, H., Choi, W. S., Nam, M.-H., et al. (2026) · BMC Infectious Diseases · doi:10.1186/s12879-026-13416-1 · Cited by 1 · see citing works
Implementing responsible artificial intelligence-driven precision medicine in critical care
Ennouri, E., Boussarsar, M., Saida, I. B., Meddeb, K., & Toumi, R. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-36554-6.00021-0
- Authors
- Komorowski, M., & Lemyze, M.
- Affiliations
- Charing Cross Hospital (GB)
- Centre Hospitalier d'Arras (FR)
- Corresponding author
- Komorowski, Matthieu
- Venue
- British Journal of Anaesthesia
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 123
- Issue
- 1
- Pages
- 14-16
- ISSN
- 0007-0912 (ISSN-L)
- OpenAlex
- W2943902158
- Cited by
- 8
- References
- 16
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2023: 2 · 2022: 1 · 2019: 1
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- British Journal of Anaesthesia (publishedVersion)
- PubMed (publishedVersion)
- Spiral (Imperial College London) (submittedVersion, cc-by-nc-nd)
- Funders
- Engineering and Physical Sciences Research Council (1675244)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Health Sciences › Medicine › Epidemiology › Sepsis Diagnosis and Treatment
- Physical Sciences › Mathematics › Statistics and Probability › Statistical Methods in Clinical Trials
- Keywords
- machine learning, randomized controlled trials, acute respiratory distress syndrome, sepsis, ICU-acquired weakness, delirium, open lung ventilation, positive end-expiratory pressure, mechanical ventilation, trial design, negative trial results
- MeSH terms
- Machine Learning, Critical Care, Humans, Respiratory Distress Syndrome
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review