The DOI matches its Crossref record; 124 of the 124 references it cites were found in a registry or an index.
Epidemiology and risk factors for delirium across hospital settings
Open accessAbstract
Delirium is one of the most common causes of acute end-organ dysfunction across hospital settings, occurring in as high as 80% of critically ill patients that require intensive care unit (ICU) care. The implications of this acute form of brain injury are profound. Across many hospital settings (emergency department, general medical ward, postoperative and ICU), a patient who experiences delirium is more likely to experience increased short- and long-term mortality, decreases in long-term cognitive function, increases in hospital length of stay and increased complications of hospital care. With the development of reliable setting-specific delirium-screening instruments, researchers have been able to highlight the predisposing and potentially modifiable risk factors that place patients at highest risk. Among the large number of risk factors discovered, administration of potent sedative medications, most notably benzodiazepines, is most consistently and strongly associated with an increased burden of delirium. Alternatively, in both the hospital and ICU, delirium can be prevented with the application of protocols that include early mobility/exercise. Future studies must work to understand the epidemiology across settings and focus upon modifiable risk factors that can be integrated into existing delirium prevention and treatment protocols.
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Self-citationA Multicomponent Intervention to Prevent Delirium in Hospitalized Older Patients
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Cited by
Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review
Nikooie, R., Neufeld, K. J., Oh, E. S., Wilson, L. M., Zhang, A., Robinson, K. A., & Needham, D. M. (2019) · Annals of Internal Medicine · doi:10.7326/m19-1860 · Cited by 246
Antipsychotics for treatment of delirium in hospitalised non-ICU patients
Burry, L., Mehta, S., Perreault, M. M., Luxenberg, J. S., Siddiqi, N., Hutton, B., Fergusson, D. A., Bell, C., & Rose, L. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd005594.pub3 · Cited by 237
ICU Survivorship—The Relationship of Delirium, Sedation, Dementia, and Acquired Weakness
Mart, M. F., Pun, B. T., Pandharipande, P., Jackson, J. C., & Ely, E. W. (2021) · Critical Care Medicine · doi:10.1097/ccm.0000000000005125 · Cited by 67
Self-citationCholinesterase inhibitors for the treatment of delirium in non-ICU settings
Yu, A., Wu, S., Zhang, Z., Dening, T., Zhao, S., Pinner, G., Xia, J., & Yang, D. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012494.pub2 · Cited by 45
Metadata
- Authors
- Vasilevskis, E. E., Han, J. H., Hughes, C. G., & Ely, E. W.
- Venue
- Best Practice & Research Clinical Anaesthesiology
- Publisher
- Elsevier BV
- Published
- 2012-09
- Volume
- 26
- Issue
- 3
- Pages
- 277-287
- ISSN
- 1521-6896 (ISSN-L)
- OpenAlex
- W2076591528
- Cited by
- 391
- References
- 124
- FWCI
- 10.20
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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