Carving Out New Transdiagnostic Dimensions for Research in Mental Health

Transdiagnostic approaches to mental health problems: Current status and future directions.

Dalgleish, T., Black, M., Johnston, D., & Bevan, A. (2020) · Journal of Consulting and Clinical Psychology · doi:10.1037/ccp0000482 · Cited by 883 · see citing works

Characterizing a psychiatric symptom dimension related to deficits in goal-directed control

Gillan, C. M., Kosinski, M., Whelan, R., Phelps, E. A., & Daw, N. D. (2016) · eLife · doi:10.7554/elife.11305 · Cited by 586 · see citing works

Psychiatric Symptom Dimensions Are Associated With Dissociable Shifts in Metacognition but Not Task Performance

Rouault, M., Seow, T. X. F., Gillan, C. M., & Fleming, S. M. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.12.017 · Cited by 312 · see citing works

Machine learning and big data in psychiatry: toward clinical applications

Rutledge, R. B., Chekroud, A. M., & Huys, Q. J. M. (2019) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2019.02.006 · Cited by 195 · see citing works

Associations between aversive learning processes and transdiagnostic psychiatric symptoms in a general population sample

Wise, T., & Dolan, R. J. (2020) · Nature Communications · doi:10.1038/s41467-020-17977-w · Cited by 113 · see citing works

Incentives Boost Model-Based Control Across a Range of Severity on Several Psychiatric Constructs

Patzelt, E. H., Kool, W., Millner, A. J., & Gershman, S. J. (2019) · Biological Psychiatry · doi:10.1016/j.biopsych.2018.06.018 · Cited by 94 · see citing works

Comparison of the Association Between Goal-Directed Planning and Self-reported Compulsivity vs Obsessive-Compulsive Disorder Diagnosis

Gillan, C. M., Kalanthroff, E., Evans, M., Weingarden, H. M., Jacoby, R. J., Gershkovich, M., Snorrason, Í., Campeas, R. B., Cervoni, C., Crimarco, N., et al. (2019) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2019.2998 · Cited by 89 · see citing works

Transdiagnostic Phenotyping Reveals a Host of Metacognitive Deficits Implicated in Compulsivity

Seow, T. X. F., & Gillan, C. (2019) · Scientific Reports · doi:10.1038/s41598-020-59646-4 · Cited by 82 · see citing works

Transdiagnostic variations in impulsivity and compulsivity in obsessive-compulsive disorder and gambling disorder correlate with effective connectivity in cortical-striatal-thalamic-cortical circuits

Parkes, L., Tiego, J., Aquino, K. M., Braganza, L., Chamberlain, S. R., Fontenelle, L. F., Harrison, B. J., Lorenzetti, V., Paton, B. K., Razi, A., et al. (2019) · NeuroImage · doi:10.1016/j.neuroimage.2019.116070 · Cited by 53 · see citing works

How Local and Global Metacognition Shape Mental Health

Seow, T. X. F., Rouault, M., Gillan, C. M., & Fleming, S. M. (2021) · Biological Psychiatry · doi:10.1016/j.biopsych.2021.05.013 · Cited by 159 · see citing works

Computational Psychiatry Needs Time and Context

Hitchcock, P., Fried, E. I., & Frank, M. J. (2021) · Annual Review of Psychology · doi:10.1146/annurev-psych-021621-124910 · Cited by 135 · see citing works

Identifying Transdiagnostic Mechanisms in Mental Health Using Computational Factor Modeling

Wise, T., Robinson, O. J., & Gillan, C. M. (2023) · Biological Psychiatry · doi:10.1016/j.biopsych.2022.09.034 · Cited by 108 · see citing works

Smartphones and the Neuroscience of Mental Health

Gillan, C. M., & Rutledge, R. B. (2021) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-101220-014053 · Cited by 84 · see citing works

Functional neuroimaging in psychiatry and the case for failing better

Nour, M. M., Liu, Y., & Dolan, R. J. (2022) · Neuron · doi:10.1016/j.neuron.2022.07.005 · Cited by 88 · see citing works

Drug development for Autism Spectrum Disorder (ASD): Progress, challenges, and future directions

McCracken, J. T., Anagnostou, E. A., Arango, C., Dawson, G., Farchione, T. R., Mantua, V., McPartland, J. C., Murphy, D., Pandina, G., & Veenstra-VanderWeele, J. M. (2021) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2021.05.010 · Cited by 87 · see citing works

Psychedelic therapy's transdiagnostic effects: A research domain criteria (RDoC) perspective

Kelly, J. R., Gillan, C. M., Prenderville, J., Kelly, C., Harkin, A., Clarke, G., & O'Keane, V. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.800072 · Cited by 69 · see citing works

Distress tolerance across substance use, eating, and borderline personality disorders: A meta-analysis

Mattingley, S., Youssef, G. J., Manning, V., Graeme, L., & Hall, K. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2021.12.126 · Cited by 65 · see citing works

Psychiatrically relevant signatures of domain-general decision-making and metacognition in the general population

Benwell, C., Mohr, G., Wallberg, J., Kouadio, A., & Ince, R. A. A. (2022) · npj Mental Health Research · doi:10.1038/s44184-022-00009-4 · Cited by 59 · see citing works

Model-Based Planning Deficits in Compulsivity Are Linked to Faulty Neural Representations of Task Structure

Seow, T. X. F., Benoit, E., Dempsey, C., Jennings, M., Maxwell, A., O'Connell, R., & Gillan, C. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0031-21.2021 · Cited by 35 · see citing works

Pavlovian-to-Instrumental Transfer across Mental Disorders: A Review

Garbusow, M., Ebrahimi, C., Riemerschmid, C., Daldrup, L., Rothkirch, M., Chen, K., Chen, H., Belanger, M. J., Hentschel, A., Smolka, M. N., et al. (2022) · Neuropsychobiology · doi:10.1159/000525579 · Cited by 70 · see citing works

Computational models of subjective feelings in psychiatryPreprint

Kao, C.-H., Feng, G., Hur, J. K., Jarvis, H., & Rutledge, R. B. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.105008 · Cited by 46 · see citing works

Impulsivity and compulsivity as parallel mediators of emotion dysregulation in eating‐related addictive‐like behaviors, alcohol use, and compulsive exercise

Mantilla, E. F., Clinton, D. N., Monell, E., Levallius, J., & Birgegård, A. (2021) · Brain and Behavior · doi:10.1002/brb3.2458 · Cited by 31 · see citing works

Association of temporal discounting with transdiagnostic symptom dimensions

Keidel, K., Lu, X., Suzuki, S., Murawski, C., & Ettinger, U. (2024) · npj Mental Health Research · doi:10.1038/s44184-024-00060-3 · Cited by 9 · see citing works

Understanding mental health through computers: An introduction to computational psychiatry

Martínez, J. C. C., & Santamaría‐García, H. A. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1092471 · Cited by 11 · see citing works

Damage to the dorsolateral prefrontal cortex is associated with repetitive compulsive behaviors in patients with penetrating brain injury

Fremont, R., Dworkin, J. D., Manoochehri, M., Krüeger, F., Huey, E. D., & Grafman, J. H. (2022) · BMJ Neurology Open · doi:10.1136/bmjno-2021-000229 · Cited by 11 · see citing works

A framework for parsing psychopathological heterogeneity: initial application in a large-scale unselected community sample

Wu, C., Yuan, C., Fan, Y.-Q., Hong, A., Wu, Z.-L., & Wang, Z. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06960-8 · Cited by 4 · see citing works

Social Anxiety Strategies Through Gaming

Copeman, M., & Freeman, J. (2022) · Lecture notes in computer science · doi:10.1007/978-3-031-05637-6_19 · Cited by 4 · see citing works

Mentalizing difficulties are transdiagnostic and explain links between mental health and neurodevelopmental symptoms and social adjustment in school‐aged children

Devine, R. T., Byrne, I., & Kovatchev, V. (2025) · JCPP Advances · doi:10.1002/jcv2.70034 · Cited by 3 · see citing works

Fundamental features of social environments determine rate of social affiliation

Garud, S., Rascu, M., Hamilton, S., Yu, I., Rushworth, M. F. S., & Klein-Flügge, M. C. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2506243122 · Cited by 2 · see citing works

Understanding Individual Differences in Mental Health and Video Games

Copeman, M., & Freeman, J. (2023) · Lecture notes in computer science · doi:10.1007/978-3-031-35979-8_13 · Cited by 1 · see citing works

Transdiagnostic approaches to precision medicine: A Computational Psychiatry PrimerPreprint

Illingworth, B. J. G., Sandhu, T., Smith, E., Lage, C., McCoy, B., & Lawson, R. P. (2022) · doi:10.22541/au.166672691.16173006/v1 · Cited by 1 · see citing works

Transdiagnostic approaches to precision medicine: A Computational Psychiatry PrimerPreprint

Illingworth, B. J. G., Sandhu, T., Smith, E. M., Lage, C., McCoy, B., & Lawson, R. P. (2022) · doi:10.22541/au.166672691.16173006/v2

Friend Request Accepted: Fundamental Features of Social Environments Determine Rate of Social AffiliationPreprint

Garud, S., Rascu, M., Hamilton, S., Yu, I. H., Rushworth, M. F. S., & Klein-Flügge, M. C. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.05.636557

The different mediation role of habit features between intolerance of uncertainty and psychopathological symptom dimensions: A transdiagnostic perspective.

Yuan, C., Fan, Y.-Q., Wu, C., Hong, A., Ou, Y., & Wang, Z. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.03.099

Transdiagnostic approach for neuropsychiatric symptoms using neuroimage

Koike, S. (2025) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.13801 · Cited by 1 · see citing works

Transdiagnostic approach in studying mental health conditions: The contribution of fundamental and translational brain research for precise interventions

(2026) · Frontiers research topics · doi:10.3389/978-2-8325-8000-4

The Neural Correlates of Transdiagnostic Dimensions of Psychopathology

Barch, D. M. (2017) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2017.17030289 · Cited by 34 · see citing works

Cognition across the psychiatric disorder spectrum: From mental health to clinical diagnosis

(2015) · Frontiers research topics · doi:10.3389/978-2-88919-653-1 · Cited by 1 · see citing works

Considerations for operationalizing transdiagnostic approaches in mental health research and practice.

Pujji, S. D., & Dinzeo, T. J. (2024) · Translational Issues in Psychological Science · doi:10.1037/tps0000425 · Cited by 1 · see citing works