Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease
Rothman, Sarah M., Herdener, Nathan, Frankola, Kathryn A., Mughal, Mohamed R., Mattson, Mark P.·2013·Brain Research
Cited by (172)
Items 101–172 of 172
- Sleep Deprivation, a Link Between Post-Traumatic Stress Disorder and Alzheimer’s DiseaseVedad Delic, Whitney A. Ratliff, Bruce A. Citron · 2021 · Journal of Alzheimer s Disease
- Acute and Chronic Sleep Deprivation-Related Changes in N-methyl-D-aspartate Receptor—Nitric Oxide Signalling in the Rat Cerebral Cortex with Reference to Aging and Brain LateralizationZdeňka Krištofiková, Jana Šírová, Jan Klaschka, Saak Victor Ovsepian · 2019 · International Journal of Molecular Sciences
- Resetting the Aging Clock: Implications for Managing Age-Related DiseasesAliza K. De Nobrega, Kristine V. Luz, Lisa C. Lyons · 2020 · Advances in experimental medicine and biology
- Shift work is significantly and positively associated with dementia: A meta-analysis studyKuo-Wei Lee, Chen‐Cheng Yang, Chun‐Hung Chen, Chih‐Hsing Hung, Hung‐Yi Chuang · 2023 · Frontiers in Public Health
- Day‐to‐day sleep variability with Alzheimer's biomarkers in at‐risk elderlyAndrée‐Ann Baril, Cynthia Picard, Anne Labonté, Erlan Sanchez, Catherine Duclos, Béry Mohammediyan, Nicholas James Ashton, Henrik Zetterberg, Kaj Blennow, John C.S. Breitner et al. · 2024 · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- The missing link between sleep disorders and age-related dementia: recent evidence and plausible mechanismsFeng Zhang, Rujia Zhong, Song Li, Raymond Chuen‐Chung Chang, Weidong Le · 2017 · Journal of Neural Transmission
- Could curcumin protect the dendritic trees of the CA1 neurons from shortening and shedding induced by chronic sleep restriction in rats?Ali Noorafshan, Fatemeh Karimi, Ali‐Mohammad Kamali, Saied Karbalay‐Doust, Mohammad Nami · 2018 · Life Sciences
- Drugs for Targeted Therapies of Alzheimer’s DiseaseChit Tam, Jack Ho Wong, Tzi Bun Ng, Stephen Kwok‐Wing Tsui, Tao Zuo · 2018 · Current Medicinal Chemistry
- Disruption of sleep macro- and microstructure in Alzheimer’s disease: overlaps between neuropsychology, neurophysiology, and neuroimagingA C Kegyes-Brassai, Róbert Pierson-Bartel, Gergő Bolla, Anita Kamondi, Andras Attila Horvath · 2024 · GeroScience
- Chronic Sleep Disturbances Alters Sleep Structure and Tau Phosphorylation in AβPP/PS1 AD Mice and Their Wild-Type LittermatesFeng Zhang, Long Niu, Rujia Zhong, Song Li, Weidong Le · 2023 · Journal of Alzheimer s Disease
- Wie Schlaf und Alzheimer-Krankheit zusammenhängenMarc Aurel Busche, Maja Kekuš, Hans Förstl · 2016 · Der Nervenarzt
- Sleep Disturbance is Associated With Higher Plasma Aβ Levels in Cognitively Normal Adults—A Population-Based Cross-Sectional StudyYao Gao, Shan Wei, Fan Gao, Ling Gao, Liangjun Dang, Suhang Shang, Chen Chen, Kang Huo, Jingyi Wang, Jin Wang et al. · 2021 · Frontiers in Aging Neuroscience
- Metabolic Disturbances Induced by Sleep Restriction as Potential Triggers for Alzheimer’s DiseaseJesús Enrique García‐Aviles, Rebeca Méndez‐Hernández, Mara A. Guzmán‐Ruiz, Miguel Cruz, Natalí N. Guerrero‐Vargas, Javier Velázquez‐Moctezuma, Gabriela Hurtado‐Alvarado · 2021 · Frontiers in Integrative Neuroscience
- Therapeutic implications of circadian clocks in neurodegenerative diseasesYu Chen Chang, Jin Young Kim · 2019 · Journal of Neuroscience Research
- Sleep reduction: A link to other neurobiological diseasesAnil Kumar, Priyanka Chanana · 2014 · Sleep and Biological Rhythms
- Sleep Dysfunction in Huntington’s Disease: Impacts of Current Medications and Prospects for TreatmentNatalia E. Owen, Roger A. Barker, Zanna J. Voysey · 2023 · Journal of Huntington s Disease
- “Boomerang Neuropathology” of Late-Onset Alzheimer’s Disease is Shrouded in Harmful “BDDS”: Breathing, Diet, Drinking, and Sleep During AgingDaulatzai, Mak Adam · 2015 · Neurotoxicity Research
- The day‐night differences in cognitive and anxiety‐like behaviors of mice after chronic sleep restrictionShuang Zhai, Mengmei Yin, Huaiqing Sun, Xue‐Qin Jiang, Yun Liu, Charles Marshall, Ting Wu, Ming Xiao · 2023 · The FASEB Journal
- Causal relationship between sleep disorders and the risk of Alzheimer's disease: A Mendelian randomization studyWenwen Xiang, Yu Shen, Shenjian Chen, Huadong Tan, Qian Cao, Lijun Xu · 2024 · Sleep Medicine
- Cutamesine Overcomes REM Sleep Deprivation-Induced Memory Loss: Relationship to Sigma-1 Receptor OccupancyNisha K. Ramakrishnan, Marianne Schepers, Gert Luurtsema, Csaba J. Nyakas, Philip H. Elsinga, Kiichi Ishiwata, Rudi Dierckx, Aren van Waarde · 2014 · Molecular Imaging and Biology
- Effects of long-term sleep disruption on cognitive function and brain amyloid-β burden: a case-control studyJana Thomas, Sharon J. Ooms, Lara J. Mentink, Jan Booij, Marcel G. M. Olde Rikkert, Sebastiaan Overeem, Roy P. C. Kessels, Jurgen A.H.R. Claassen · 2020 · Alzheimer s Research & Therapy
- Pathobiolgy and Management of Alzheimer's DiseaseHoowon Kim, Ji Yeon Chung · 2021 · Chonnam Medical Journal
- Association between cyclic variation in the heart rate index and biomarkers of neurodegenerative diseases in obstructive sleep apnea syndrome: A pilot studyCheng-Yu Tsai, Yi-Shin Liu, Arnab Majumdar, Robert Houghton, Shang‐Yang Lin, Yin-Tzu Lin, Shu‐Chuan Ho, Wun-Hao Cheng, Wen‐Te Liu, Dean Wu et al. · 2022 · Journal of Clinical Neuroscience
- Naturalistic Measurement of Sleep in Older Adults with Amnestic Mild Cognitive Impairment: Anxiety Symptoms Do Not Explain Sleep DisturbanceMarina G. Cavuoto, Glynda Kinsella, Ben Ong, Kerryn Elizabeth Pike, Christian L. Nicholas · 2019 · Current Alzheimer Research
- Postoperative 24-h Acute Sleep Deprivation Improves Learning and Memory Through Inhibition of Tau Phosphorylation in the Hippocampal Neurons of Splenectomized RatsYu-Wei Zhang, Xiaoqian Li, Wenfei Tan, Bo Fang, Hong Ma · 2020 · Nature and Science of Sleep
- Melatonin Rescues the Dendrite Collapse Induced by the Pro-Oxidant Toxin Okadaic Acid in Organotypic Cultures of Rat Hilar HippocampusHéctor Solís-Chagoyán, Aline Domínguez-Alonso, Marcela Valdés-Tovar, Jesús Argueta, Zuly A. Sánchez-Florentino, E. Calixto, G. Benítez-King · 2020 · Molecules
- Time-restricted feeding rescues circadian disruption-aggravated progression of Alzheimer's disease in diabetic miceXuemin Peng, Rongping Fan, Lei Xie, Xiaoli Shi, Fen Wang, Weijie Xu, Kun Dong, Shujun Zhang, Delin Ma, Xuefeng Yu et al. · 2022 · The Journal of Nutritional Biochemistry
- The overnight reduction of amyloid β 1‐42 plasma levels is diminished by the extent of sleep fragmentation, sAPP‐β, and APOE ε4 in psychiatrists on callTimo Grimmer, Theresa Laub, Alexander Hapfelmeier, Tamara Eisele, Bastian Fatke, Patricia Hölzle, Sandra Lüscher, Anna‐Mareike Parchmann, Michael Rentrop, Dirk Schwerthöffer et al. · 2020 · Alzheimer s & Dementia
- REM Sleep Loss-Induced Elevated Noradrenaline Plays a Significant Role in Neurodegeneration: Synthesis of Findings to Propose a Possible Mechanism of Action from Molecule to Patho-Physiological ChangesShatrunjai Giri, Rachna Mehta, Birendra Nath Mallick · 2023 · Brain Sciences
- Sleep and Tau Pathology in Vietnam War Veterans with Preclinical and Prodromal Alzheimer’s DiseaseMurray Andrews, Ryan Ross, Atul Malhotra, Sonia Ancoli‐Israel, James B. Brewer, Sarah Jane Banks, Alzheimer’s Disease Neuroimaging Initiative · 2021 · Journal of Alzheimer s Disease Reports
- Impact of circadian and diurnal rhythms on cellular metabolic function and neurodegenerative diseasesS. Kendall Smith, Erik S. Musiek · 2020 · International review of neurobiology
- Physiological and Neurobehavioral Consequences of Chronic Sleep Restriction in Rodent ModelsSamüel Deurveilher, Kazue Semba · 2019 · Handbook of behavioral neuroscience
- Toward Prevention and Reduction of Alzheimer’s DiseaseAntonia González-Madrid, Camila Calfío, Andrea González, Valentina Lüttges, Ricardo Benjamin Maccioni · 2023 · Journal of Alzheimer s Disease
- Tau pathology reprograms glucose metabolism to support cortical hyperexcitability, excitatory/inhibitory imbalance, and sleep lossRiley E. Irmen, Sierra M. Turner, James Andy Snipes, Kaelyn H. Schloss, Xiaodan Wang, Holden C. Williams, Gopal V. Velmurugan, Jerry B. Hunt, Junyan Li, Patrick G. Sullivan et al. · 2026 · npj Dementia
- Investigation of the effects of curcumin and piperine on cyclophosphamide‐induced brain injury in ratsSerpil Aygörmez, Şaban Maraşlı · 2024 · Journal of Biochemical and Molecular Toxicology
- Circadian rhythm in neurodegenerative disease: the role of RNA modifications and potential application of RNA-based therapeuticsGaolin Jiang, Lin Yuan, Xiaoyue Liu, Huixiang Wu, Haoran Yu, Wanlu Zhang, Sihui Zhang, Yongye Huang · 2024 · Ageing and Neurodegenerative Diseases
- Electrophysiological insights into Alzheimer's disease: A review of human and animal studiesKirsten Calvin, Adam M. McNeela, Amanda M. Leisgang Osse, Guncha Bhasin, Matthew Ridenour, Jefferson W. Kinney, J.M. Hyman · 2024 · Neuroscience & Biobehavioral Reviews
- Circadian rhythm disruption and retinal dysfunction: a bidirectional link in Alzheimer's disease?Laura Carrero, Desireé Antequera, Cristina Municio, Eva Carro · 2023 · Neural Regeneration Research
- Enhanced homeostatic sleep response and decreased neurodegenerative proteins in cereblon knock-out miceJun‐Hyung Jung, Jin‐Hong Kim, Uroos Akber, Na Young Lee, Jeong-Won Baek, Jieun Jung, Min-Cheol Park, Jiseung Kang, Seungje Jeon, Chul‐Seung Park et al. · 2024 · Communications Biology
- Sleep disorders and Alzheimer’s diseaseAnna Nicolaevna Bogolepova · 2018 · Neurology neuropsychiatry Psychosomatics
- Altered Sigma-1 Receptor Expression in Two Animal Models of Cognitive ImpairmentNisha K. Ramakrishnan, Krisztina Marosi, Csaba J. Nyakas, Chantal Kwizera, Philip H. Elsinga, Kiichi Ishiwata, Paul G.M. Luiten, Rudi Dierckx, Aren van Waarde · 2014 · Molecular Imaging and Biology
- The circadian clock regulates scavenging of fluid-borne substrates by brain border-associated macrophagesHelena J. Barr, Sydney K. Caldwell, Justin M. Reimertz, Constanze Depp, Alec J. Walker, Samuel E. Marsh, Anushree S. Gupte, Maximilian Hingerl, Jasmin Patel, Sang-O Park et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Sleep disturbances and Alzheimer’s disease: a multiscale approach from exposome to neurobiology and precision medicineMasoud Tahmasian, Jorik D Elberse, Reihaneh Ahmadi, Liu Wen, Ivana Rosenzweig, Sarah Genon, Simon Bodo Eickhoff, Bryce A. Mander · 2026 · GeroScience
- Selective REM sleep restriction in mice using a device designed for tunable somatosensory stimulationDillon Huffman, Asmaa Abbas Ajwad, Anuj Agarwal, Michael E. Lhamon, Kevin D. Donohue, Bruce F. O’Hara, Sridhar Sunderam · 2024 · Journal of Neuroscience Methods
- Sleep Disorders in Neurologic PracticeLori A. Panossian, Alon Y. Avidan · 2016 · Neurologic Clinics
- Association of spermidine blood levels with microstructure of sleep—implications from a population-based studySilke Maria Wortha, Juliane Schulz, Jevri Hanna, Claudia Schwarz, Beate Stubbe, Stefan Frenzel, Robin Bülow, Nele Friedrich, Matthias A. Nauck, Henry Völzke et al. · 2023 · GeroScience
- Upsetting the Balance: How Modifiable Risk Factors Contribute to the Progression of Alzheimer’s DiseaseCaitlin M. Carroll, Ruth M. Benca · 2024 · Biomolecules
- Rescuing impaired hippocampal-cortical interactions and spatial reorientation learning and memory during sleep in a mouse model of Alzheimer’s disease using hippocampal 40 Hz stimulationSarah Danielle Cushing, Shawn C. Moseley, Alina C. Stimmell, Christopher W. Schatschneider, Aaron A. Wilber · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Associations between night/shift working and late-life brain healthJosh King‐Robson, Jennifer M. Nicholas, Sarah‐Naomi James, Ashvini Keshavan, Dylan M. Williams, James Groves, Carole H. Sudre, Kirsty Lu, Josephine Barnes, William Coath et al. · 2025 · Brain Communications
- Sleep deprivation enhances amyloid beta peptide, p-tau and serotonin in the brain: Neuroprotective effects of nanowired delivery of cerebrolysin with monoclonal antibodies to amyloid beta peptide, p-tau and serotoninAruna Sharma, Lianyuan Feng, Dafin Fior Muresanu, Z. Ryan Tian, José Vicente Lafuente, Anca Dana Buzoianu, Ala Nozari, Igor Bryukhovetskiy, Igor Manzhulo, Lars Wiklund et al. · 2023 · International review of neurobiology
- Clock/Sleep-Dependent Learning and Memory in Male 3xTg-AD Mice at Advanced Disease Stages and Extrinsic Effects of Huprine X and the Novel Multitarget Agent AVCRI104P3Lydia Giménez‐Llort, Mikel Santana-Santana, Míriam Ratia, Belén Pérez, Pelayo Camps, Diego Muñoz‐Torrero, Albert Badı́a, M. Victòria Clos · 2021 · Brain Sciences
- Insufficient Sleep and Alzheimer’s Disease: Potential Approach for Therapeutic Treatment MethodsDieu Quynh Trinh, Huynh Nhu, Duc Toan Pham · 2024 · Brain Sciences
- Molecular and environmental drivers of tau post-translational modifications and tau pathologyTrevor M. Price, Autumn E. Tucker, Kristen E. Funk · 2026 · Ageing Research Reviews
- Life Experience Matters: Enrichment and Stress Can Influence the Likelihood of Developing Alzheimer’s Disease via Gut MicrobiomeSarah E. Torraville, Cassandra M. Flynn, Tori L. Kendall, Qi Yuan · 2023 · Biomedicines
- Functional and vascular neuroimaging in maritime pilots with long-term sleep disruptionLara J. Mentink, Matthias J.P. van Osch, Leanne J. Bakker, Marcel G. M. Olde Rikkert, Christian F. Beckmann, Jurgen A.H.R. Claassen, Koen V. Haak · 2024 · GeroScience
- Wie Schlaf und Alzheimer-Krankheit zusammenhängen: Insomnie, Amnesie und AmyloidMarc Aurel Busche, Maja Kekuš, Hans Förstl · 2017 · Der Nervenarzt
- The Impact of Long Working Hours on Cognitive Function: A Follow-Up Study with Gender Stratification1Seunghyun Lee, Joon Yul Choi, Wanhyung Lee · 2021 · Journal of Alzheimer s Disease
- Deep Brain Stimulation of Nucleus Basalis of Meynert improves learning in rat model of dementiaDeepak Kumbhare, Megan Rajagopal, Jamie Toms, Anne H. Freelin, George R. Weistroffer, Nicholas McComb, Sindhu Karnam, Adel Azghadi, Kevin Sean Murnane, Mark S. Baron et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- The Sleep-Wake System and Alzheimer's DiseaseDenise Sharon · 2015 · Advances in psychology, mental health, and behavioral studies (APMHBS) book series
- Sleep, Adenosine, and NeurodegenerationTheresa E. Bjorness, Robert W. Greene · 2017 · Elsevier eBooks
- Sleep abnormality as a potential target of disease-modifying therapy for neurodegenerative diseasesEiko Nakano Minakawa · 2019 · Folia Pharmacologica Japonica
- Anti-dementia Medications: Specific AgentsFeng Zhang, Xinyao Liu, Yufei Liu, Yan‐Jiang Wang, Weidong Le · 2020 · Springer eBooks
- A novel bioinformatics approach to reveal the role of circadian oscillations in AD developmentZhiwei Ji, Dazhi Shang, Pora Kim, Mengyuan Yang, Sijia Wu, Weiling Zhao, Eunju Kim, Marvin Wirianto, Zheng Chen, Seung Hee Yoo et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- What is the Relationship Between Sleep and Alzheimer’s Disease? A Narrative ReviewSamuel Gobraeil, Gina Rizq · 2022 · Undergraduate Research in Natural and Clinical Science and Technology (URNCST) Journal
- Advances in Research and Treatment on Patients with Alzheimer's disease Induced by Sleep disordersSijing Li · 2022 · Highlights in Science Engineering and Technology
- Anti-dementia Medications: Specific AgentsFeng Zhang, Xinyao Liu, Yufei Liu, Yan‐Jiang Wang, Weidong Le · 2022 · Springer eBooks
- The effect of long-term sleep disruption on the brain – looking beyond amyloidLara J. Mentink, Matthias J.P. van Osch, L.J. Bakker, Marcel G. M. Olde Rikkert, Christian F. Beckmann, Jurgen A.H.R. Claassen, Koen V. Haak · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 1 of Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer’s disease by decreasing brain O-GlcNAc cycling in miceKim, Dong Yeol, Kim, Sang-Min, Han, Inn-Oc · 2024 · Figshare
- Additional file 2 of Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer’s disease by decreasing brain O-GlcNAc cycling in miceKim, Dong Yeol, Kim, Sang-Min, Han, Inn-Oc · 2024 · Figshare
- Chronic short sleep in early life accelerates cognitive decline via disrupted proteostasisRobert Komlo, Kamalini Sengupta, Ewa Strus, Nirinjini N. Naidoo · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Disruption of circadian rhythms is associated with cognitive impairment during gestationS Li, Jialu Xu, Han Yue, Jiaxin Yin, Yuqi Yuan, Sijia Ni, Haifei Wang, Yibin Zhang, Xiaobin Liao, Jing Tao et al. · 2026 · Journal of Neuroendocrinology
- Effects of early adulthood chronic sleep disruption on late life cognition, brain pathology, and microglial reactivity in the PS19 mouse model of tauopathyKerly Lozano, Haris Hillery, Kenny Vetter, Ward D. Pettibone, Sara Farahat, Ronit Witztum, Natasha V. Berryman, Rubén Fernández‐Rodríguez, Ubong S. Ekperikpe, Ilse Sofia Daehn et al. · 2026 · Scientific Reports