The DOI matches its Crossref record; 144 of the 147 references it cites were found in a registry or an index.
Plant tissue culture as a perpetual source for production of industrially important bioactive compounds
Open accessAbstract
Plants have been used throughout the world for its medicinal powers since ancient time. The pharmacological properties of plants are based on their phytochemical components especially the secondary metabolites which are outstanding sources of value added bioactive compounds. Secondary metabolites have complex chemical composition and are produced in response to various forms of stress to perform different physiological tasks in plants. They are used in pharmaceutical industries, cosmetics, dietary supplements, fragrances, flavors, dyes, etc. Extended use of these metabolites in various industrial sectors has initiated a need to focus research on increasing the production by employing plant tissue culture (PTC) techniques and optimizing their large scale production using bioreactors. PTC techniques being independent of climatic and geographical conditions will provide an incessant, sustainable, economical and viable production of secondary metabolites. This review article intends to assess the advantages of using plant tissue culture, distribution of important secondary metabolites in plant families, strategies involved for optimal metabolite production and the industrial importance of selected secondary metabolites.
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“Nowadays, plant tissue culture is a powerful tool for reproducing identical plants of a genotype from a single plant part without dependence on geographical and climatic factors [4].”
From Somaclonal Variation and Clonal Fidelity in Commercial Micropropagation: Challenges and Perspectives (2025) · cites this paper as [4]
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“Thus, plant tissue culture is an alternative method of conventional vegetative propagation [4,5].”
From Somaclonal Variation and Clonal Fidelity in Commercial Micropropagation: Challenges and Perspectives (2025) · cites this paper as [4]
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Cites
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Cited by
Sorted by citations
Plant Secondary Metabolites as Defense Tools against Herbivores for Sustainable Crop Protection
Divekar, P. A., Srinivasa, N., Divekar, B. A., KUMAR, R. R., Gowda, G. B., Ray, A., Singh, A. K., Rani, V., Singh, V., Singh, A. K., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052690 · Cited by 789
Meena, M., Swapnil, P., Divyanshu, K., Kumar, S., Mangesh, H., Tripathi, Y. N., Zehra, A., Marwal, A., & Upadhyay, R. S. (2020) · Journal of Basic Microbiology · doi:10.1002/jobm.202000370 · Cited by 388
Self-citationSwapnil, P., Meena, M., Singh, S. K., Dhuldhaj, U. P., Harish, & Marwal, A. (2021) · Current Plant Biology · doi:10.1016/j.cpb.2021.100203 · Cited by 371
Self-citationPlant Growth-Promoting Rhizobacteria as a Green Alternative for Sustainable Agriculture
Chandran, H., Meena, M., & Swapnil, P. (2021) · Sustainability · doi:10.3390/su131910986 · Cited by 254
Self-citationProduction of bioactive plant secondary metabolites through in vitro technologies—status and outlook
Wawrosch, C., & Zotchev, S. B. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11539-w · Cited by 252
Metadata
- Authors
- Chandran, H., Meena, M., Barupal, T., & Sharma, K.
- Affiliations
- Mohanlal Sukhadia University (IN)
- Corresponding author
- Meena, Mukesh
- Venue
- Biotechnology Reports
- Publisher
- Elsevier BV
- Published
- 2020-06
- Volume
- 26
- Pages
- e00450
- ISSN
- 2215-017X (ISSN-L)
- PMC
- PMC7193120
- OpenAlex
- W3019219369
- Cited by
- 462
- References
- 147
- Citations by year
- 2026: 44 · 2025: 78 · 2024: 92 · 2023: 102 · 2022: 83 · 2021: 52 · 2020: 11
- FWCI
- 5.94
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Biotechnology Reports (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- University Grants Committee
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant tissue culture and regeneration
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Transgenic Plants and Applications
- Keywords
- plant tissue culture, secondary metabolites, bioactive compounds, bioreactors, mass production, medicinal plants, phytochemicals
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