The DOI matches its Crossref record; 144 of the 147 references it cites were found in a registry or an index.
Plant tissue culture as a perpetual source for production of industrially important bioactive compounds
Open accessAbstract
Plants have been used throughout the world for its medicinal powers since ancient time. The pharmacological properties of plants are based on their phytochemical components especially the secondary metabolites which are outstanding sources of value added bioactive compounds. Secondary metabolites have complex chemical composition and are produced in response to various forms of stress to perform different physiological tasks in plants. They are used in pharmaceutical industries, cosmetics, dietary supplements, fragrances, flavors, dyes, etc. Extended use of these metabolites in various industrial sectors has initiated a need to focus research on increasing the production by employing plant tissue culture (PTC) techniques and optimizing their large scale production using bioreactors. PTC techniques being independent of climatic and geographical conditions will provide an incessant, sustainable, economical and viable production of secondary metabolites. This review article intends to assess the advantages of using plant tissue culture, distribution of important secondary metabolites in plant families, strategies involved for optimal metabolite production and the industrial importance of selected secondary metabolites.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The cited source says what the claim attributes to it.
In the citing paper
“Nowadays, plant tissue culture is a powerful tool for reproducing identical plants of a genotype from a single plant part without dependence on geographical and climatic factors [4].”
From Somaclonal Variation and Clonal Fidelity in Commercial Micropropagation: Challenges and Perspectives (2025) · cites this paper as [4]
The cited source says what the claim attributes to it.
In the citing paper
“Thus, plant tissue culture is an alternative method of conventional vegetative propagation [4,5].”
From Somaclonal Variation and Clonal Fidelity in Commercial Micropropagation: Challenges and Perspectives (2025) · cites this paper as [4]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
MYB transcription factors in Arabidopsis
Dubos, C., Stracke, R., Erich Grotewold, A., Weißhaar, B., Martin, C. R., & Lepiniec, L. (2010) · Trends in Plant Science · doi:10.1016/j.tplants.2010.06.005 · Cited by 4,885
Ekor, M. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00177 · Cited by 3,919
Discovery and resupply of pharmacologically active plant-derived natural products: A review
Atanasov, A. G., Waltenberger, B., Pferschy‐Wenzig, E., Linder, T., Wawrosch, C., Uhrín, P., Temml, V., Wang, L., Schwaiger, S., Heiß, E. H., et al. (2015) · Biotechnology Advances · doi:10.1016/j.biotechadv.2015.08.001 · Cited by 3,105
Influence of abiotic stress signals on secondary metabolites in plants
Ramakrishna, A., & Ravishankar, G. A. (2011) · Plant Signaling & Behavior · doi:10.4161/psb.6.11.17613 · Cited by 2,526
The Traditional Medicine and Modern Medicine from Natural Products
Yuan, H.-D., Ma, Q., Li, Y., & Piao, G. (2016) · Molecules · doi:10.3390/molecules21050559 · Cited by 2,451
Elicitor signal transduction leading to production of plant secondary metabolites
Zhao, J. H., Davis, L. C., & Verpoorte, R. (2005) · Biotechnology Advances · doi:10.1016/j.biotechadv.2005.01.003 · Cited by 1,985
Transcriptional control of flavonoid biosynthesis by MYB–bHLH–WDR complexes
Xu, W., Dubos, C., & Lepiniec, L. (2015) · Trends in Plant Science · doi:10.1016/j.tplants.2014.12.001 · Cited by 1,933
The Shikimate Pathway and Aromatic Amino Acid Biosynthesis in Plants
Maeda, H. A., & Dudareva, N. (2012) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-042811-105439 · Cited by 1,568
Herrmann, K. M., & Weaver, L. M. (1999) · Annual Review of Plant Physiology and Plant Molecular Biology · doi:10.1146/annurev.arplant.50.1.473 · Cited by 1,343
Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery
Thomford, N. E., Senthebane, D. A., Rowe, A., Munro, D., Seele, P. P., Maroyi, A., & Dzobo, K. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19061578 · Cited by 1,301
Flagged first, then by citations
3 of the 147 references couldn’t be matched to a known paper.
Research works printed but not linked: 5
- Palazón, 1997, Application of transformed root technology to the production of bioactive metabolites, Recent Res. Dev. Plant Physiol., 1, 125
- Bhowal, 2017, Coleus forskholii: phytochemical and pharmacological profile, Int. J. Pharm. Sci. Res., 8, 3599
- Srinivas Reddy, 2011, Approaches to enhance the production of Forskolin in cell cultures of Coleus forskohlii Briq, Int. J. Pharm. Sci., 3, 1434
- Christen, 1989, Cell cultures as a means to produce taxol, Proc. Amer. Assoc. Canc. Res., 30, 566
- Khadke, 2013, Direct somatic embryogenesis and plant regeneration from leaf and stem explants of N. foetida: acritically endangered plant species, Intl. J. Plant An. Envi. Sci., 3, 257
Cited by
Sorted by citations
Plant Secondary Metabolites as Defense Tools against Herbivores for Sustainable Crop Protection
Divekar, P. A., Srinivasa, N., Divekar, B. A., KUMAR, R. R., Gowda, G. B., Ray, A., Singh, A. K., Rani, V., Singh, V., Singh, A. K., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052690 · Cited by 789
Meena, M., Swapnil, P., Divyanshu, K., Kumar, S., Mangesh, H., Tripathi, Y. N., Zehra, A., Marwal, A., & Upadhyay, R. S. (2020) · Journal of Basic Microbiology · doi:10.1002/jobm.202000370 · Cited by 388
Self-citationSwapnil, P., Meena, M., Singh, S. K., Dhuldhaj, U. P., Harish, & Marwal, A. (2021) · Current Plant Biology · doi:10.1016/j.cpb.2021.100203 · Cited by 371
Self-citationPlant Growth-Promoting Rhizobacteria as a Green Alternative for Sustainable Agriculture
Chandran, H., Meena, M., & Swapnil, P. (2021) · Sustainability · doi:10.3390/su131910986 · Cited by 254
Self-citationProduction of bioactive plant secondary metabolites through in vitro technologies—status and outlook
Wawrosch, C., & Zotchev, S. B. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11539-w · Cited by 252
Aware, C. B., Patil, D. N., Suryawanshi, S. S., Mali, P., Rane, M. R., Gurav, R. G., & Jadhav, J. P. (2022) · South African Journal of Botany · doi:10.1016/j.sajb.2022.05.028 · Cited by 283
Plant Growth Regulation in Cell and Tissue Culture In Vitro
Pasternak, T. P., & Steinmacher, D. A. (2024) · Plants · doi:10.3390/plants13020327 · Cited by 295
Microbial Biodiversity and Bioremediation Assessment Through Omics Approaches
Chandran, H., Meena, M., & Sharma, K. (2020) · Frontiers in Environmental Chemistry · doi:10.3389/fenvc.2020.570326 · Cited by 197
Self-citationIn vitro strategies for the enhancement of secondary metabolite production in plants: a review
Fazili, M. A., Bashir, I., Ahmad, M., Yaqoob, U., & Geelani, S. N. (2022) · Bulletin of the National Research Centre/Bulletin of the National Research Center · doi:10.1186/s42269-022-00717-z · Cited by 185
Rizvi, S. A. A., Einstein, G. P., Tulp, O. L., Sainvil, F., & Branly, R. (2022) · Biomolecules · doi:10.3390/biom12101442 · Cited by 181
Endophytic Nanotechnology: An Approach to Study Scope and Potential Applications
Meena, M., Zehra, A., Swapnil, P., Harish, Marwal, A., Yadav, G., & Sonigra, P. (2021) · Frontiers in Chemistry · doi:10.3389/fchem.2021.613343 · Cited by 173
Self-citationArbuscular mycorrhizal fungi and production of secondary metabolites in medicinal plants
Zhao, Y., Cartabia, A., Lalaymia, I., & Declerck, S. (2022) · Mycorrhiza · doi:10.1007/s00572-022-01079-0 · Cited by 187
Anjitha, K. S., Sameena, P. P., & Puthur, J. T. (2021) · Plant Stress · doi:10.1016/j.stress.2021.100038 · Cited by 164
Chen, D., Mubeen, B., Hasnain, A., Rizwan, M., Adrees, M., Naqvi, S. A. H., Iqbal, S., Kamran, M. A., El-Sabrout, A. M., Elansary, H. O., et al. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.881032 · Cited by 166
Hasnain, A., Naqvi, S. A. H., Ayesha, S. I., Khalid, F., Ellahi, M., Iqbal, S., Hassan, M. Z., Abbas, A., Adamski, R., Markowska, D., et al. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.1009395 · Cited by 186
Plant Cell Cultures: Biofactories for the Production of Bioactive Compounds
Bapat, V. A., Kishor, P. B. K., Naravula, J., Jain, S. M., & Suprasanna, P. (2023) · Agronomy · doi:10.3390/agronomy13030858 · Cited by 125
Plant cell cultures as heterologous bio-factories for secondary metabolite production
Wu, T., Kerbler, S. M., Fernie, A. R., & Zhang, Y. (2021) · Plant Communications · doi:10.1016/j.xplc.2021.100235 · Cited by 130
Singh, V. K., & Kumar, A. (2023) · Symbiosis · doi:10.1007/s13199-023-00925-9 · Cited by 123
Yadav, G., & Meena, M. (2021) · Biotechnology Reports · doi:10.1016/j.btre.2021.e00629 · Cited by 120
Self-citationSonigra, P., & Meena, M. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.608649 · Cited by 114
Self-citationBiological-based methods for the removal of volatile organic compounds (VOCs) and heavy metals
Meena, M., Sonigra, P., & Yadav, G. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-11112-4 · Cited by 110
Self-citationEnhancing secondary metabolite production in plants: Exploring traditional and modern strategies
Selwal, N., Rahayu, F., Herwati, A., Latifah, E., Supriyono, S., Suhara, C., Suastika, I. B. K., Mahayu, W. M., & Wani, A. K. (2023) · Journal of Agriculture and Food Research · doi:10.1016/j.jafr.2023.100702 · Cited by 110
Physiology of medicinal and aromatic plants under drought stress
Bistgani, Z. E., Barker, A. V., & Hashemi, M. (2024) · The Crop Journal · doi:10.1016/j.cj.2023.12.003 · Cited by 98
Esparza, L. M. A., Vigo, E. F. A., Villagrán, Z., Lafitte, E. D. R., Ruvalcaba-Gómez, J. M., Solano-Cornejo, M. Á., Zamora-Gasga, V. M., Montalvo‐González, E., Rodríguez, H. G., Aldrete, C. E. A., et al. (2023) · Molecules · doi:10.3390/molecules28237752 · Cited by 93
Hesami, M., & Jones, A. M. P. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11375-y · Cited by 90
Aasım, M., Katırcı, R., Akgur, O., Yildirim, B., Mustafa, Z., Nadeem, M. A., Baloch, F. S., Karaköy, T., & Yılmaz, G. (2022) · Industrial Crops and Products · doi:10.1016/j.indcrop.2022.114801 · Cited by 88
Multifarious Responses of Forest Soil Microbial Community Toward Climate Change
Meena, M., Yadav, G., Sonigra, P., Nagda, A., Mehta, T., Swapnil, P., Harish, Marwal, A., & Kumar, S. (2022) · Microbial Ecology · doi:10.1007/s00248-022-02051-3 · Cited by 87
Self-citationModeling and optimizing in vitro seed germination of industrial hemp (Cannabis sativa L.)
Hesami, M., Pepe, M., Monthony, A. S., Baiton, A., & Jones, A. M. P. (2021) · Industrial Crops and Products · doi:10.1016/j.indcrop.2021.113753 · Cited by 82
Temporary Immersion System for Production of Biomass and Bioactive Compounds from Medicinal Plants
Carlo, A. D., Tarraf, W., Lambardi, M., & Benelli, C. (2021) · Agronomy · doi:10.3390/agronomy11122414 · Cited by 77
Nabi, N., Singh, S. K., & Saffeullah, P. (2021) · In Vitro Cellular & Developmental Biology - Plant · doi:10.1007/s11627-020-10140-6 · Cited by 80
Semenov, M. V., Zhelezova, A. D., Ksenofontova, N. A., Ivanova, E. A., Nikitin, D. A., & Semenov, V. M. (2025) · Agronomy · doi:10.3390/agronomy15020335 · Cited by 76
Arbuscular mycorrhizal Fungi and Changes in Primary and Secondary Metabolites
Machiani, M. A., Javanmard, A., Machiani, R. H., & Sadeghpour, A. (2022) · Plants · doi:10.3390/plants11172183 · Cited by 74
Exploring the role of elicitors in enhancing medicinal values of plants under in vitro condition
Guru, A., Dwivedi, P., Kaur, P., & Pandey, D. K. (2021) · South African Journal of Botany · doi:10.1016/j.sajb.2021.10.014 · Cited by 73
Impact of Nanomaterials on Plant Secondary Metabolism
Selvakesavan, R. K., Kruszka, D., Shakya, P., Mondal, D., & Franklin, G. (2023) · Springer eBooks · doi:10.1007/978-3-031-20878-2_6 · Cited by 71
El-Ramady, H. R., Hajdú, P., Törős, G., Badgar, K., Llanaj, X., Kiss, A., Abdalla, N. A., Omara, A. E.-D., Elsakhawy, T. A., Elbasiouny, H., et al. (2022) · Sustainability · doi:10.3390/su14148329 · Cited by 71
Biotechnology and In Vitro Culture as an Alternative System for Secondary Metabolite Production
Mohaddab, M., Goumi, Y. E., Gallo, M., Montesano, D., Zengin, G., Bouyahya, A., & Fakiri, M. (2022) · Molecules · doi:10.3390/molecules27228093 · Cited by 68
Shah, M., Jan, H., Drouet, S., Tungmunnithum, D., Shirazi, J. H., Hano, C., & Abbasi, B. H. (2021) · Molecules · doi:10.3390/molecules26040791 · Cited by 63
Genetic Manipulation and Bioreactor Culture of Plants as a Tool for Industry and Its Applications
Kowalczyk, T., Merecz-Sadowska, A., Picot, L., Karačonji, I. B., Wieczfińska, J., Śliwiński, T., & Sitarek, P. (2022) · Molecules · doi:10.3390/molecules27030795 · Cited by 61
Plant hairy roots for the production of extracellular vesicles with antitumor bioactivity
Boccia, E., Alfieri, M., Belvedere, R., Santoro, V., Colella, M., Gaudio, P. D., Moros, M., Piaz, F. D., Petrella, A., Leone, A., et al. (2022) · Communications Biology · doi:10.1038/s42003-022-03781-3 · Cited by 62
Shen, N., Ren, J., Liu, Y., Sun, W., Li, Y., Xin, H., & Cui, Y. (2022) · Food Chemistry · doi:10.1016/j.foodchem.2022.134422 · Cited by 53
Singh, Y., Kumar, U., Panigrahi, S., Balyan, P., Mehla, S., Sihag, P., Sagwal, V., Singh, K. P., White, J. C., & Dhankher, O. P. (2023) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2023.108004 · Cited by 58
A comprehensive review on application of bioreactor for industrial wastewater treatment
Meena, M., Yadav, G., Sonigra, P., & Shah, M. P. (2021) · Letters in Applied Microbiology · doi:10.1111/lam.13557 · Cited by 52
Self-citationChauhan, P. K., Upadhyay, S. K., Rajput, V. D., Dwivedi, P., Minkina, T., & Wong, M. H. (2024) · Environmental Geochemistry and Health · doi:10.1007/s10653-023-01823-1 · Cited by 49
Niazian, M., & Sabbatini, P. (2021) · Planta · doi:10.1007/s00425-021-03771-5 · Cited by 47
Tissue culture mediated biotechnological interventions in medicinal trees: recent progress
Arora, K., Manoj, K., & Sharma, A. (2022) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-022-02298-1 · Cited by 50
Somaclonal Variation and Clonal Fidelity in Commercial Micropropagation: Challenges and Perspectives
Majumder, S., Igamberdiev, A. U., & Debnath, S. C. (2025) · Agronomy · doi:10.3390/agronomy15061489 · Cited by 46
Application of In Vitro Plant Tissue Culture Techniques to Halophyte Species: A Review
Custódio, L. M. B., Charles, G., Magné, C., Barba‐Espín, G., Piqueras, A., Hernández, J. A., Hamed, K. B., Castañeda‐Loaiza, V., Fernandes, E., & Rodrigues, M. J. (2022) · Plants · doi:10.3390/plants12010126 · Cited by 45
Plant secondary metabolites-mediated plant defense against bacteria and fungi pathogens
Yang, W., Zhang, L., Yang, P., Xiang, H., & Yang, P. (2024) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2024.109224 · Cited by 49
Miclea, I., Suhani, A., Zăhan, M., & Bunea, A. (2020) · Agronomy · doi:10.3390/agronomy10111722 · Cited by 46
Nanotechnology in Plant Metabolite Improvement and in Animal Welfare
Rahmawati, M., Mahfud, C., Risuleo, G., & Jadid, N. (2022) · Applied Sciences · doi:10.3390/app12020838 · Cited by 43
Singh, D. B., Pathak, R. K., & Rai, D. (2022) · Revista Brasileira de Farmacognosia · doi:10.1007/s43450-022-00235-z · Cited by 46
The potential roles of gossypol as anticancer agent: advances and future directions
Paunovic, D., Rajković, J., Novaković, R., Grujić-Milanović, J. D., Mekky, R. H., Popa, D. G., Călina, D. C., & Sharifi‐Rad, J. (2023) · Chinese Medicine · doi:10.1186/s13020-023-00869-8 · Cited by 42
The role of biocatalysis in the asymmetric synthesis of alkaloids – an update
Cigan, E., Eggbauer, B., Schrittwieser, J. H., & Kroutil, W. (2021) · RSC Advances · doi:10.1039/d1ra04181a · Cited by 38
Marine bacteria and omic approaches: A novel and potential repository for bioremediation assessment
Hassan, S., Sabreena, Khurshid, Z., Bhat, S. A., Kumar, V., Ameén, F., & Ganai, B. A. (2022) · Journal of Applied Microbiology · doi:10.1111/jam.15711 · Cited by 37
García-Pérez, P., Zhang, L., Miras‐Moreno, B., Lozano-Milo, E., Landín, M., Lucini, L., & Gallego, P. P. F. (2021) · Plants · doi:10.3390/plants10112430 · Cited by 42
Khan, T., Khan, M. A., Karam, K., Ullah, N., Mashwani, Z., & Nadhman, A. (2021) · Frontiers in Plant Science · doi:10.3389/fpls.2021.610194 · Cited by 36
Sharma, R., Bhat, Z. F., Kumar, A., Kumar, S., Bekhit, A. E. A., & Naqvi, Z. B. (2021) · Journal of Food Safety · doi:10.1111/jfs.12909 · Cited by 37
Bioremediation of industrial effluents: A synergistic approach
Nagda, A., Meena, M., & Shah, M. P. (2021) · Journal of Basic Microbiology · doi:10.1002/jobm.202100225 · Cited by 35
Self-citationArbuscular Mycorrhizal Fungi and Higher Plants
Ahammed, G. J., & Hajiboland, R. (2024) · Springer eBooks · doi:10.1007/978-981-99-8220-2 · Cited by 35
Resource recovery of bioactive compounds from food waste and their diverse industrial applications
Chauhan, S., Pandit, N. K., Mohanty, A., & Meena, S. S. (2025) · Biomass Conversion and Biorefinery · doi:10.1007/s13399-023-04967-3 · Cited by 29
Humbal, A., & Pathak, B. (2023) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-023-02612-5 · Cited by 29
Harnessing metabolites from plant cell tissue and organ culture for sustainable biotechnology
Yapa, A. W., Hiti-Bandaralage, J., & Pathirana, R. N. (2025) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-025-03180-6 · Cited by 29
García-Pérez, P., Lozano-Milo, E., Landín, M., & Gallego, P. P. F. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.576177 · Cited by 32
Biotechnological approaches for the production of camptothecin
Banadka, A., Sudheer, W. N., Dandin, V. S., Naik, P. M., Vennapusa, A. R., Melmaiee, K., Vemanna, R. S., Al-Khayri, J. M., Thiruvengadam, M., & Nagella, P. (2024) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-024-13187-2 · Cited by 27
Acharjee, S., Kumar, R., & Kumar, N. (2021) · Industrial Crops and Products · doi:10.1016/j.indcrop.2021.114298 · Cited by 26
Biological control of plant diseases by endophytes
Yadav, G., & Meena, M. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91245-7.00007-9 · Cited by 25
Self-citationPrashant, S. P., & Mishra, B. (2024) · Physiologia Plantarum · doi:10.1111/ppl.14400 · Cited by 25
Pandino, G., Bonomo, A., Scavo, A., Mauromicale, G., & Lombardo, S. (2022) · Scientia Horticulturae · doi:10.1016/j.scienta.2022.111180 · Cited by 25
Qahtan, A. A., Faisal, M., Alatar, A. A., & Abdel-Salam, E. M. (2022) · Plants · doi:10.3390/plants11121614 · Cited by 25
Antioxidant Green Factories: Toward Sustainable Production of Vitamin E in Plant In Vitro Cultures
Muthulakshmi, M., Srinivasan, A., & Srivastava, S. (2023) · ACS Omega · doi:10.1021/acsomega.2c05819 · Cited by 27
Rezaei, H., Mirzaie-Asl, A., Abdollahi, M. R., & Tohidfar, M. (2023) · PLoS ONE · doi:10.1371/journal.pone.0285657 · Cited by 25
Żbik, K., Onopiuk, A., Szpicer, A., & Kurek, M. A. (2023) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-023-02158-2 · Cited by 29
Gómez‐Ramos, G. A., Prado‐Barragán, L. A., Rivera, B. A., Huerta‐Ochoa, S., Rivera, V. M., Couder‐García, M., García‐Hernández, R. D. L. Á., & Castillo-Araiza, C. O. (2024) · Chemical Engineering & Technology · doi:10.1002/ceat.202400289 · Cited by 27
Javed, R., Yücesan, B., Zia, M., & Gürel, E. (2022) · Springer eBooks · doi:10.1007/978-981-19-2503-0_10 · Cited by 24
A review: improvement of plant tissue culture applications by using nanoparticles
Balamurugan, V., Abdi, G., Karthiksaran, C., Nedumaran, T., & Dhanarajan, A. (2024) · Journal of Nanoparticle Research · doi:10.1007/s11051-024-06103-2 · Cited by 23
Collection of Hairy Roots as a Basis for Fundamental and Applied Research
Stepanova, A. Y., Malunova, M. V., Gladkov, E. A., Evsyukov, S. V., Tereshonok, D. V., & Соловьева, А. И. (2022) · Molecules · doi:10.3390/molecules27228040 · Cited by 23
Golkar, P., Akbari, R., Bazarganipour, M., & Javed, R. (2023) · Plant Physiology and Biochemistry · doi:10.1016/j.plaphy.2023.107741 · Cited by 23
Zahid, M., Khalid, S., Raana, S., Amin, S., Javaid, H., Arshad, R., Jahangeer, A., Ahmad, S., & Hassan, S. A. (2024) · Future Foods · doi:10.1016/j.fufo.2024.100328 · Cited by 22
Mueangnak, K., Kitwetcharoen, H., Thanonkeo, P., Klanrit, P., Apiraksakorn, J., Klanrit, P., Klanrit, P., & Thanonkeo, P. (2025) · Scientific Reports · doi:10.1038/s41598-024-83096-x · Cited by 21
Enhanced Secondary Metabolite Production in Hairy Root Cultures Through Biotic and Abiotic Elicitors
Kaur, G., Prakash, P., Srivastava, R., & Verma, P. C. (2020) · Reference series in phytochemistry · doi:10.1007/978-3-030-30185-9_38 · Cited by 21
Niazian, M., Howyzeh, M. S., & Sadat-Noori, S. A. (2021) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-021-02096-1 · Cited by 20
Sustainable Production of Ajuga Bioactive Metabolites Using Cell Culture Technologies: A Review
Popova, E., Титова, М. В., Тыныкулов, М., Zakirova, R. P., Куличенко, И. Е., Prudnikova, O. N., & Nosov, A. M. (2023) · Nutrients · doi:10.3390/nu15051246 · Cited by 23
Makowski, W., Królicka, A., Tokarz, B., Szopa, A., Ekiert, H., & Tokarz, K. M. (2023) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-023-02487-6 · Cited by 20
Zayed, A., Farag, M. A., Mehring, A., Salem, M. A., Ibrahim, R. M., Alseekh, S., Fernie, A. R., & Ulber, R. (2023) · Phytochemistry · doi:10.1016/j.phytochem.2023.113777 · Cited by 20
Suspension culture of somatic embryos for the production of high-value secondary metabolites
Murthy, H. N., Joseph, K. S., Hahn, J.-E., Lee, H.-S., Paek, K., & Park, S. (2023) · Physiology and Molecular Biology of Plants · doi:10.1007/s12298-023-01365-x · Cited by 20
Bansal, Y., Mujib, A., Mamgain, J., Syeed, R., Mohsin, M., Nafees, A., Dewir, Y. H., & Mendler‐Drienyovszki, N. (2024) · Frontiers in Plant Science · doi:10.3389/fpls.2024.1433634 · Cited by 19
Deciphering nutrient stress in plants: integrative insight from metabolomics and proteomics
Moshood, A. Y., Abdulraheem, M. I., Li, L., Zhang, Y., Raghavan, V., & Hu, J. (2025) · Functional & Integrative Genomics · doi:10.1007/s10142-025-01551-y · Cited by 20
Haida, Z., Sinniah, U. R., Nakasha, J. J., & Hakiman, M. (2022) · Horticulturae · doi:10.3390/horticulturae8080740 · Cited by 19
Ji, B., Xuan, L., Zhang, Y., Mu, W., Paek, K., Park, S., Wang, J., & Gao, W. (2023) · Plants · doi:10.3390/plants12071505 · Cited by 22
Kaur, J., Dhar, S. K., Chauhan, A., Yadav, S., Mudgal, G., Asyakina, L. K., Atuchin∥⊥, V. V., & Abdi, G. (2023) · Current Plant Biology · doi:10.1016/j.cpb.2023.100308 · Cited by 20
Hagaggi, N. S. A., Abdul-Raouf, U. M., & Radwan, T. A. A. (2024) · BMC Plant Biology · doi:10.1186/s12870-024-04747-9 · Cited by 20
Lescano, L., Cziáky, Z., Custódio, L. M. B., & Rodrigues, M. J. (2025) · Plant Cell Tissue and Organ Culture (PCTOC) · doi:10.1007/s11240-025-02991-x · Cited by 18
Halder, M., Majumder, A., Ray, S., & Jha, S. (2021) · Sustainable development and biodiversity · doi:10.1007/978-3-030-74779-4_16 · Cited by 18
Intracellular Pathways and Mechanisms of Colored Secondary Metabolites in Cancer Therapy
Sevastre, A.-S., Manea, E. V., Popescu, Ş. O., Tache, D. E., Dănoiu, S., Sfredel, V., Tătăranu, L. G., & Dricu, A. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23179943 · Cited by 19
Sharma, A., Pandey, H., Devadas, V. A. S. N., Kartha, B. D., & Jha, R. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.2c08162 · Cited by 18
Roshni, P. T., & Rekha, P. D. (2024) · Physiology and Molecular Biology of Plants · doi:10.1007/s12298-024-01426-9 · Cited by 18
Nanoparticle-assisted elicitation of therapeutically important secondary metabolites in plants
Vyavahare, G. D., Patil, R. R., & Park, J. H. (2025) · Plant Growth Regulation · doi:10.1007/s10725-025-01388-2 · Cited by 17
Nano-Elicitation Approaches for Boosting Secondary Metabolites in Medicinal Plant Cell Cultures
Golkar, P., Vázquez-Núñez, E., & Peralta-Videa, J. R. (2025) · Plants · doi:10.3390/plants15010046 · Cited by 17
Nomura, T., Yoneda, A., Ogita, S., & Kato, Y. (2021) · Applied Biochemistry and Biotechnology · doi:10.1007/s12010-021-03629-2 · Cited by 17
Purification and characterisation of uricase from Bacillus subtilis SP6
Pustake, S. O., Bhagwat, P. K., Pillai, S., & Dandge, P. B. (2021) · Process Biochemistry · doi:10.1016/j.procbio.2021.12.010 · Cited by 17
Metadata
- Authors
- Chandran, H., Meena, M., Barupal, T., & Sharma, K.
- Affiliations
- Mohanlal Sukhadia University (IN)
- Corresponding author
- Meena, Mukesh
- Venue
- Biotechnology Reports
- Publisher
- Elsevier BV
- Published
- 2020-06
- Volume
- 26
- Pages
- e00450
- ISSN
- 2215-017X (ISSN-L)
- PMC
- PMC7193120
- OpenAlex
- W3019219369
- Cited by
- 462
- References
- 147
- Citations by year
- 2026: 44 · 2025: 78 · 2024: 92 · 2023: 102 · 2022: 83 · 2021: 52 · 2020: 11
- FWCI
- 5.94
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- Biotechnology Reports (publishedVersion, cc-by-nc-nd)
- PubMed Central (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- University Grants Committee
- Topics
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant tissue culture and regeneration
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biotechnology › Transgenic Plants and Applications
- Keywords
- plant tissue culture, secondary metabolites, bioactive compounds, bioreactors, mass production, medicinal plants, phytochemicals
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
