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Integrated Analysis Reveals Critical Ferroptosis Regulators and FTL Contribute to Cancer Progression in Hepatocellular Carcinoma

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Ferroptosis regulates key signaling pathways in gastrointestinal tumors: Underlying mechanisms and therapeutic strategies

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Mechanistic elucidation of ferroptosis and ferritinophagy: implications for advancing our understanding of arthritis

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All-trans retinoic acid inhibits the malignant behaviors of hepatocarcinoma cells by regulating ferroptosis

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Expression and Prognostic Significance of Ferroptosis-related Proteins SLC7A11 and GPX4 in Renal Cell Carcinoma

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Research progress on the occurrence and therapeutic mechanism of ferroptosis in NSCLC

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Ferroptosis Biology and Implication in Cancers

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LTBP2 Knockdown Promotes Ferroptosis in Gastric Cancer Cells through p62‐Keap1‐Nrf2 Pathway

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Deciphering the link: ferroptosis and its role in glioma

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Ferroptosis of epithelial ovarian cancer: genetic determinants and therapeutic potential

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Ferroptosis‐Related Long Noncoding RNAs Have Excellent Predictive Ability for Multiomic Characteristics of Bladder Cancer

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New perspectives on ferroptosis and its role in hepatocellular carcinoma

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Ferroptosis: the vulnerability within a cancer monster

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Combating drug resistance in hepatocellular carcinoma: No awareness today, no action tomorrow

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Boric acid Increases Susceptibility to Chemotherapy by Targeting the Ferritinophagy Signaling Pathway in TMZ Resistant Glioblastoma Cells

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Ginsenoside RK1 Induces Ferroptosis in Hepatocellular Carcinoma Cells through an FSP1-Dependent Pathway

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SPARC regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma

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Role of ferroptosis inhibitors in the management of diabetes

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Construction and Validation of a Combined Ferroptosis and Hypoxia Prognostic Signature for Hepatocellular Carcinoma

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Emerging Potential Therapeutic Targets of Ferroptosis in Skeletal Diseases

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Novel Insights on Ferroptosis Modulation as Potential Strategy for Cancer Treatment: When Nature Kills

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Effective Synergy of Sorafenib and Nutrient Shortage in Inducing Melanoma Cell Death through Energy Stress

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Atovaquone enhances antitumor efficacy of TCR-T therapy by augmentation of ROS-induced ferroptosis in hepatocellular carcinoma

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Targeting cell death mechanisms: the potential of autophagy and ferroptosis in hepatocellular carcinoma therapy

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Identification of the Prognostic Signature Associated With Tumor Immune Microenvironment of Uterine Corpus Endometrial Carcinoma Based on Ferroptosis-Related Genes

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Bevacizumab induces ferroptosis and enhances CD8+ T cell immune activity in liver cancer via modulating HAT1 and increasing IL-9

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Ferroptosis in head and neck squamous cell carcinoma: from pathogenesis to treatment

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Research progress on ferroptosis in the pathogenesis and treatment of neurodegenerative diseases

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The role of non-apoptotic cell death in the treatment and drug-resistance of digestive tumors

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Roles and Mechanisms of Ferroptosis in Sorafenib Resistance for Hepatocellular Carcinoma

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Identification of Novel Prognostic Risk Signatures of Soft Tissue Sarcoma Based on Ferroptosis-Related Genes

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Prognostic Role and Potential Mechanisms of the Ferroptosis-Related Metabolic Gene Signature in Hepatocellular Carcinoma

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Pharmacological Targeting of Ferroptosis in Cancer Treatment

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Targeting Ferroptosis Pathways: A Novel Strategy for Cancer Therapy

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OIT3 serves as a novel biomarker of hepatocellular carcinoma by mediating ferroptosis via regulating the arachidonic acid metabolism

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Ferroptosis and its emerging role in tumor

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Identification of Ferroptosis-Associated Genes in Prostate Cancer by Bioinformatics Analysis

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Ferroptosis: The functions of Nrf2 in human embryonic stem cells

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Identifying the potential genes in alpha synuclein driving ferroptosis of Parkinson’s disease

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Ferroptosis Mediation Patterns Reveal Novel Tool to Implicate Immunotherapy and Multi-Omics Characteristics in Bladder Cancer

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Knockdown of AKR1C3 Promoted Sorafenib Sensitivity Through Inhibiting the Phosphorylation of AKT in Hepatocellular Carcinoma

Zheng, J., Yang, Z.-H., Li, Y., Yang, L., & Yao, R. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.823491 · Cited by 16

Novel Insights in the Regulatory Mechanisms of Ferroptosis in Hepatocellular Carcinoma

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A Ferroptosis-Related LncRNA Signature Associated with Prognosis, Tumor Immune Environment, and Genome Instability in Hepatocellular Carcinoma

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The Growing Skyline of Advanced Hepatocellular Carcinoma Treatment: A Review

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Development and validation of four ferroptosis-related gene signatures and their correlations with immune implication in hepatocellular carcinoma

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Arginase 2 negatively regulates sorafenib-induced cell death by mediating ferroptosis in melanoma

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Ferroptosis: a new promising target for hepatocellular carcinoma therapy

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Programmed cell death and melatonin: A comprehensive review

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Hemin promotes platelet activation and plasma membrane disintegration regulated by the subtilisin‐like proprotein convertase furin

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Identification of Ferroptosis-Related Molecular Clusters and Immune Characterization in Autism Spectrum Disorder

Liu, L., Lai, Y., Zhan, Z., Fu, Q., & Jiang, Y. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.911119 · Cited by 14

Identification of a ferroptosis-related lncRNA signature with prognosis for Wilms tumor

Liu, H., Zhang, M., Zhang, T., Shi, M., Lu, W., Yang, S., Cui, Q., & Li, Z. (2021) · Translational Pediatrics · doi:10.21037/tp-21-211 · Cited by 13

Comprehensive Analysis of the Tumor Microenvironment and Ferroptosis-Related Genes Predict Prognosis with Ovarian Cancer

Li, X., Xiong, L., Wen, Y., & Zhang, Z. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.774400 · Cited by 14

Targeting ferroptosis with flavonoids for cancer therapy: Mechanisms and opportunities

Gong, G., Zhang, Z., & Zheng, Y. (2026) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2025.189528 · Cited by 13

Engineering Iron-Based Nanomaterials for Breast Cancer Therapy Associated with Ferroptosis

Wei, R., Fu, G., Li, Z., Liu, Y., & Xue, M. (2024) · Nanomedicine · doi:10.2217/nnm-2023-0270 · Cited by 12

Potential therapies for HCC involving targeting the ferroptosis pathway

Li, D. (2024) · American Journal of Cancer Research · doi:10.62347/sigp9279 · Cited by 16

Ferroptosis in cancer (Review)

Zeng, L., Liu, X., Geng, C., Gao, X., & Liu, L. (2024) · Oncology Letters · doi:10.3892/ol.2024.14437 · Cited by 13

Therapeutic potential of synthetic and natural iron chelators against ferroptosis

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The Mechanisms of Ferroptosis and the Applications in Tumor Treatment: Enemies or Friends?

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A comprehension and systematic insight into the interaction between ferroptosis and virus infection: The implications of mechanisms and strategies

Niu, S., Deng, Y., Yang, Y., Wang, J., Fang, C., Zhou, Y., & Dai, H. (2025) · Virulence · doi:10.1080/21505594.2025.2532806 · Cited by 12

Integrative Multi-Omics Analysis of Identified Ferroptosis-Marker RPL8 as a Candidate Oncogene Correlates with Poor Prognosis and Immune Infiltration in Liver Cancer

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Role of Exosomal Non-coding RNAs in Gastric Cancer: Biological Functions and Potential Clinical Applications

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Ferroptosis and its impact on common diseases

Zou, P., He, Q., Xia, H., & Zhong, W. (2024) · PeerJ · doi:10.7717/peerj.18708 · Cited by 10

The Ferroptosis Molecular Subtype Reveals Characteristics of the Tumor Microenvironment, Immunotherapeutic Response, and Prognosis in Gastric Cancer

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Mechanistic Insights about Sorafenib-, Valproic Acid- and Metformin-Induced Cell Death in Hepatocellular Carcinoma

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A Prognostic Model of Pancreatic Cancer Based on Ferroptosis-Related Genes to Determine Its Immune Landscape and Underlying Mechanisms

Yu, X., Zheng, Q., Zhang, M., Zhang, Q., Zhang, S., He, Y., & Guo, W. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.746696 · Cited by 10

In desmoid-type fibromatosis cells sorafenib induces ferroptosis and apoptosis, which are enhanced by autophagy inhibition

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Cell Death and Disease

Xu, K. (2022) · Biochemistry · doi:10.5772/intechopen.104360 · Cited by 9

Deciphering sorafenib resistance in hepatocellular carcinoma via ferroptotic mechanisms

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A prognostic risk prediction model based on ferroptosis-related long non-coding RNAs in bladder cancer: A bulk RNA-seq research and scRNA-seq validation

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Brusatol improves the efficacy of sorafenib in Huh7 cells via ferroptosis resistance dependent Nrf2 signaling pathway

Liu, X., Liu, T., Zhou, Z., Bian, K., Qiu, C., & Zhang, F. (2024) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2024.150762 · Cited by 8

Targeting ferroptosis reveals a new strategy for breast cancer treatment: a bibliometric study

Liu, J., Tang, R., Zheng, J., & Luo, K. (2024) · Discover Oncology · doi:10.1007/s12672-024-01569-x · Cited by 8

Ferroptosis in Cancer Immunotherapy—Implications for Hepatocellular Carcinoma

Kusnick, J., Bruneau, A., Tacke, F., & Hammerich, L. (2022) · Immuno · doi:10.3390/immuno2010014 · Cited by 9

Transcriptional Patterns of Lower‐Grade Glioma Patients with Distinct Ferroptosis Levels, Immunotherapy Response, and Temozolomide Sensitivity

Tu, Z., Li, J., Long, X., Wu, L., Zhu, X., & Huang, K. (2022) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2022/9408886 · Cited by 8

The advancements in targets for ferroptosis in liver diseases

Xiang, X., Gao, J., Su, D., & Shi, D. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1084479 · Cited by 8

Novel Ferroptosis-Related Multigene Prognostic Models for Patients with Bladder Cancer

Zhang, S., Wang, C., Xia, W., Duan, H., Qian, S., & Shen, H. (2021) · International Journal of General Medicine · doi:10.2147/ijgm.s339996 · Cited by 8

Targeting ferroptosis in gastrointestinal tumors: Interplay of iron-dependent cell death and autophagy

Safari, M. H., Rahimzadeh, P., Alaei, E., Alimohammadi, M., Esfandiari, N., Daneshi, S., Malgard, N., Farahani, N., Taheriazam, A., & Hashemi, M. (2025) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2025.102013 · Cited by 8

Ferroptosis-related metabolic mechanism and nanoparticulate anticancer drug delivery systems based on ferroptosis

Yan, D., Wu, Z., & Qi, X. (2023) · Saudi Pharmaceutical Journal · doi:10.1016/j.jsps.2023.02.008 · Cited by 7

Ferroptosis-related gene glutathione peroxidase 4 promotes reprogramming of glucose metabolism via Akt–mTOR axis in intrahepatic cholangiocarcinoma

Hori, Y., Yoh, T., Nishino, H., Okura, K., Kurimoto, M., Takamatsu, Y., Satoh, M., Nishio, T., Koyama, Y., Ishii, T., et al. (2023) · Carcinogenesis · doi:10.1093/carcin/bgad094 · Cited by 7

An Esterase-Responsive SLC7A11 shRNA Delivery System Induced Ferroptosis and Suppressed Hepatocellular Carcinoma Progression

Zhang, H., Wang, J., Xiang, X., Xie, C. Z., Lu, X., Guo, H., Sun, Y., Shi, Z., Song, H., Qiu, N., et al. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16020249 · Cited by 7

Exploring the Updated Roles of Ferroptosis in Liver Diseases: Mechanisms, Regulators, and Therapeutic Implications

Ge, T., Wang, Y., Han, Y., Bao, X., & Chunfeng, L. (2024) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-024-01611-3 · Cited by 7

The function of necroptosis in liver cancer

Tayir, M., Wang, Y., Chu, T., Wang, X., Fan, Y.-Q., Cao, L., Chen, Y.-H., & Wu, D. (2025) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2025.167828 · Cited by 7

Modern Outcomes Following Treatment of Hepatocellular Carcinoma in Hereditary Hemochromatosis

McPhail, M. J. W., Khorsandi, S. E., Abbott, L., Al-Kadhimi, G., Kane, P., Karani, J. B., O’Grady, J., Heaton, N. D., Bomford, A. B., & Suddle, A. R. (2019) · American Journal of Clinical Oncology · doi:10.1097/coc.0000000000000583 · Cited by 7

Epigenetic regulation of ferroptosis in gastrointestinal cancers (Review)

Gong, L., Wu, L., Zhao, S., Xiao, S., Chu, X., Zhang, Y., Li, F., Li, S., Yang, H., & Jiang, P. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5534 · Cited by 6

Ferroptosis in hematological malignancies: molecular mechanisms and therapeutic potential

Liu, J., Liu, R., Miao, J., & He, A. (2025) · Cellular Oncology · doi:10.1007/s13402-025-01142-w · Cited by 7

Immunization Combined with Ferroptosis Related Genes to Construct a New Prognostic Model for Head and Neck Squamous Cell Carcinoma

Yang, L., Chen, Z., Liu, Y., Wang, X., Li, J., & Ye, Q. (2022) · Cancers · doi:10.3390/cancers14174099 · Cited by 6

Harnessing ferroptosis for cancer therapy: Mechanisms and therapeutic strategies (Review)

Mouawad, N., Jaafari, N. E., El‐Sibai, M., & Abi‐Habib, R. J. (2025) · Oncology Reports · doi:10.3892/or.2025.9029 · Cited by 7

Biological protein mediated ferroptotic tumor nanotherapeutics

Tao, J., Li, C., Zheng, Y., Wang, F., Zhang, M., Wu, X., Chen, Y., Zeng, Q., Chen, F., & Fei, W. (2021) · Journal of Materials Chemistry B · doi:10.1039/d1tb01289d · Cited by 5

Regulatory factor X1 promotes sorafenib-induced ferroptosis in hepatocellular carcinoma by transcriptional regulation of BECN1

Yang, Z., Yuan, Y., Niu, Y., Zuo, D., Liu, W., Li, K., Shi, Y., Qiu, Z., Li, K., Zhu, L., et al. (2024) · Cellular Oncology · doi:10.1007/s13402-024-01017-6 · Cited by 10

Iron‐dependent cell death of hepatocellular carcinoma cells exposed to sorafenib

Louandre, C., Ezzoukhry, Z., Godin, C., Barbare, J., Mazière, J., Chauffert, B., & Galmiche, A. (2013) · International Journal of Cancer · doi:10.1002/ijc.28159 · Cited by 602

Mechanism of sorafenib resistance associated with ferroptosis in HCC

Guo, L., Hu, C., Yao, M., & Han, G. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1207496 · Cited by 97

Sigma‐1 receptor protects against ferroptosis in hepatocellular carcinoma cells

Bai, T., Lei, P., Zhou, H., Liang, R., Zhu, R., Wang, W., Zhou, L., & Sun, Y. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14594 · Cited by 152

Role of ferroptosis in hepatocellular carcinoma

Nie, J., Lin, B., Zhou, M., Wu, L. J., & Zheng, T. (2018) · Journal of Cancer Research and Clinical Oncology · doi:10.1007/s00432-018-2740-3 · Cited by 234