The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Structural features and immunological activity of a polysaccharide from Dioscorea opposita Thunb roots
Open accessAbstract
Abstract A new polysaccharide (YP-1) from a variety of Chinese yam, Dioscorea opposita Thunb, having health benefits was extracted by water and further successively purified through DEAE-Cellulose A52 and Sephadex G-100 columns. YP-1 contained glucose, mannose and galactose in the molar ratio of 1:0.37:0.11. Its molecular weight was determined to be 42 kDa by high-performance gel-permeation chromatography. Structure features of the purified polysaccharide were investigated by a combination of chemical and instrumental analysis, such as methylation analysis, Smith degradation, GC–MS, 13 C and 1 H NMR and FT-IR. The results indicated that the polysaccharide has a backbone of (1→3)-linked α- d -glucopyranosyl residues, which occasionally branches at O-6. The branches were mainly composed of (1→2)-linked α- d -mannopyranosyl residues, and terminated with β- d -galactopyranosyl residues. Preliminary tests in vitro revealed that YP-1 could stimulate ConA-induced T lymphocyte proliferation and its branches are extremely important for the expression of the enhancement of the immunological activity.
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Cites
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Characterization and antitumor activity of a polysaccharide from Strongylocentrotus nudus eggs
Liu, C., Lin, Q., Gao, Y., Ye, L., Xing, Y., & Xi, T. (2007) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2006.05.024 · Cited by 168
Luo, L., Qin, T., Huang, Y., Zheng, S., Bo, R., Liu, Z., Xing, J., Hu, Y., Liu, J., & Wang, D. (2017) · Drug Delivery · doi:10.1080/10717544.2017.1359861 · Cited by 47
Metadata
- Authors
- Zhao, G., Kan, J., Li, Z., & Chen, Z.
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2005-08
- Volume
- 61
- Issue
- 2
- Pages
- 125-131
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W2049500740
- Cited by
- 262
- References
- 17
- FWCI
- 7.50
- Type
- journal article
- Language
- en
- Open access
- green
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