Characterization and antitumor activity of a polysaccharide from Strongylocentrotus nudus eggs
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Polysaccharide SEP isolated from the eggs of the sea urchin Strongylocentrotus nudus effectively inhibited the growth of S180 tumor and hepatocellular carcinoma in vivo via activation of lymphocytes and macrophages, amplification of B and T cell proliferation, and increased secretion of IL-2, TNF-α and IFN-γ.
“Polysaccharide SEP isolated from the eggs of the sea urchin Strongylocentrotus nudus effectively inhibited the growth of S180 tumor and the hepatocellular carcinoma in vivo via the activation of lymphocytes and macrophages, amplification of B and T cell proliferation, and increased secretion of such cytokines as IL-2, TNF-α and IFN-γ [138,139,140,141].”
From Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects (2013) · cites this paper as [138]
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- Authors
- Liu, C., Lin, Q., Gao, Y., Ye, L., Xing, Y., & Xi, T.
- Affiliations
- China Pharmaceutical University (CN)
- Corresponding author
- Xi, Tao
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2007-02
- Volume
- 67
- Issue
- 3
- Pages
- 313-318
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W1988500304
- Cited by
- 168
- References
- 26
- Citations by year
- 2026: 3 · 2025: 10 · 2024: 6 · 2023: 6 · 2022: 4 · 2021: 8 · 2020: 5 · 2019: 5 · 2018: 11 · 2017: 10 · 2016: 7 · 2015: 10 · 2014: 14 · 2013: 11 · 2012: 13
- FWCI
- 8.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Carbohydrate Polymers (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Echinoderm biology and ecology
- Keywords
- polysaccharides, Strongylocentrotus nudus, sea urchin eggs, anticancer activity, polysaccharide structure, sarcoma 180, immunomodulation, splenocyte proliferation, marine natural products
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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