Structural, antioxidant, and emulsifying activities of fucoidan from Saccharina japonica using pressurized liquid extraction
Abstract
Pressurized liquid extraction (PLE) was utilized to extract sulfated polysaccharides (fucoidan) from brown seaweed Saccharina japonica. Various conditions of temperature (80-200°C), pressure (5-100bar), and solvents (water, 0.1% sodium hydroxide, 0.1% formic acid, 70% ethanol, 50% ethanol, and 25% ethanol) were assessed; the best crude fucoidan (CF) yield was 8.23%, obtained from 140°C and 50bar (sodium hydroxide). Compositional analysis, FT-IR, molecular weight, monosaccharides, TGA, UV-vis, XRD, and elemental analysis confirm that extracted polysaccharides revealed the features of fucoidan. Fucose was the main monosaccharide present in CF obtained by various solvent systems. All CF showed antioxidant activities as measured by DPPH radical and ABTS(+) radical scavenging. CF demonstrates good emulsion-stabilizing capacities, especially with vegetable oils. This study demonstrates that PLE is an efficacious method for enhancing the yield of polysaccharides from S. japonica and that it could be a potential source of natural antioxidants and emulsifiers.
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Algae are a good source of dietary fibers because of non-digestible polysaccharides in the algal cell wall, which possess antioxidant, hypoglycemic, antiviral, antitumor, and anti-inflammatory activities due to fucoidan and laminarin.
“Algae are considered as a good source of dietary fibers because of the presence of non-digestible polysaccharides in the algal cell wall (Figure 3) [11]. It has been shown that they possess activities, like antioxidant [12], hypoglycemic [13], antiviral [14,15], antitumor [16], and anti-inflammatory due to the presence of fucoidan and laminarin [17].”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [12]
Crude fucoidan was examined for antioxidant activity, and some other compounds were considered to contribute to antioxidant activity.
“Crude fucoidan was examined for antioxidant activity by Saravana et al. [12], and it was considered that some other compounds contribute to antioxidant activity.”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [12]
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References 40 · Cited by 197
- Authors
- Saravana, P. S., Cho, Y.-J., Park, Y.-B., Woo, H.-C., & Chun, B.-S.
- Affiliations
- Pukyong National University (KR)
- Corresponding author
- Chun, Byung-Soo
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 153
- Pages
- 518-525
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W2513650855
- Semantic Scholar
- b723e5dabb72cdb32da66d0c000ca12728a51e69
- Cited by
- 197
- References
- 40
- Citations by year
- 2026: 16 · 2025: 26 · 2024: 27 · 2023: 20 · 2022: 21 · 2021: 21 · 2020: 19 · 2019: 12 · 2018: 21 · 2017: 13 · 2015: 1
- FWCI
- 21.98
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Carbohydrate Polymers (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Ministry of Oceans and Fisheries (20140559)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Physical Sciences › Earth and Planetary Sciences › Oceanography › Marine and coastal plant biology
- Keywords
- fucoidan, Laminaria japonica, brown algae, sulfated polysaccharides, accelerated solvent extraction, extraction optimization, fucose, antioxidant activity, emulsifying activity, emulsion stability, vegetable oils, natural antioxidants, natural emulsifiers
- MeSH terms
- Antioxidants, Emulsions, Polysaccharides, Pressure, Seaweed, Solvents, Sulfates, Temperature, Emulsifying Agents, Liquid-Liquid Extraction
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