The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Cellulose nanocrystals and cellulose nanofibrils based hydrogels for biomedical applications
Abstract
The production of cellulose nanomaterials from lignocellulosic biomass opens an opportunity for the development and application of new materials in nanotechnology. Over the last decade, cellulose nanomaterials based hydrogels have emerged as promising materials in the field of biomedical applications due to their low toxicity, biocompatibility, biodegradability, as well as excellent mechanical stability. In this review, recent progress on the preparation of cellulose nanocrystals (CNCs) and cellulose nanofibrils (CNFs) based hydrogels and their biomedical applications is summarized and discussed based on the analyses of the latest studies (especially for the reports in the past five years). We begin with a brief introduction of the differences in preparation methods and properties of two main types of cellulose nanomaterials: CNCs and CNFs isolated from lignocellulosic biomass. Then, various processes for the fabrication of CNCs based hydrogels and CNFs based hydrogels were elaborated, respectively, with the focus on some new methods (e.g. 3D printing). Furthermore, a number of biomedical applications of CNCs and CNFs based hydrogels, including drug delivery, wound dressings and tissue engineering scaffolds were highlighted. Finally, the prospects and ongoing challenges of CNCs and CNFs based hydrogels for biomedical applications were summarized. This work demonstrated that the CNCs and CNFs based hydrogels have great promise in a wide range of biomedical applications in the future.
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Cites
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Cited by
Nanocellulose: From Fundamentals to Advanced Applications
Trache, D., Tarchoun, A. F., Derradji, M., Hamidon, T. S., Masruchin, N., Brosse, N., & Hussin, M. H. (2020) · Frontiers in Chemistry · doi:10.3389/fchem.2020.00392 · Cited by 1,309
Chen, Y., Zhang, L., Yang, Y., Pang, B., Xu, W., Duan, G., Jiang, S., & Zhang, K. (2021) · Advanced Materials · doi:10.1002/adma.202005569 · Cited by 721
Cellulose Nanopaper: Fabrication, Functionalization, and Applications
Liu, W., Liu, K., Du, H., Zheng, T., Zhang, N., Xu, T., Pang, B., Zhang, X., Si, C., & Zhang, K. (2022) · Nano-Micro Letters · doi:10.1007/s40820-022-00849-x · Cited by 435
Self-citationMao, L., Hu, S., Gao, Y., Wang, L., Zhao, W., Fu, L., Cheng, H., Xia, L., Xie, S., Ye, W., et al. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.202000872 · Cited by 412
Cellulose nanocrystals: Pretreatments, preparation strategies, and surface functionalization
Rana, A. K., Frollini, E., & Thakur, V. K. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.05.119 · Cited by 412
Metadata
- Authors
- Du, H., Liu, W., Zhang, M., Si, C., Zhang, X., & Li, B.
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2019-04
- Volume
- 209
- Pages
- 130-144
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W2910507574
- Cited by
- 949
- References
- 8
- FWCI
- 31.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- Du, H., Liu, W., Zhang, M., Si, C., Zhang, X., & Li, B. (2019). Cellulose nanocrystals and cellulose nanofibrils based hydrogels for biomedical applications. Carbohydrate Polymers. https://doi.org/10.1016/j.carbpol.2019.01.020
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