The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
In vitro fermentation of Gracilaria lemaneiformis sulfated polysaccharides and its agaro-oligosaccharides by human fecal inocula and its impact on microbiota
Abstract
The fermentation behaviour of sulfated polysaccharides (GLP) and their agaro-oligosaccharides (GLO) derived from Gracilaria lemaneiformis were examined. During in vitro fermentation, GLP and GLO increased the concentrations of short chain fatty acids (SCFAs) and modulated the composition and diversity of gut microorganisms compared with control groups. GLP increased the abundance of Bacteroidetes and decreased the abundance of Firmicutes, while GLO increased the abundance of Firmicutes and Actinobacteria. Moreover, the abundances of potential pathogenic bacteria were reduced. Molecular weight and intrinsic viscosity of GLP decreased significantly from 2.15 × 105 to 1.22 × 105 Da, 374.45-113.91 mL/g, respectively. Furthermore, GLP was degraded into smaller degree of polymerization of oligosaccharides, with no significant change observed in GLO. Overall, this study revealed GLP and GLO could be beneficial for gastrointestinal tract by producing SCFAs and modulating intestinal microbes, indicating GLP and GLO are potentially sources of prebiotics in functional foods.
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Metadata
- Authors
- Zhang, X., Aweya, J. J., Huang, Z.-X., Kang, Z.-Y., Bai, Z.-H., Li, K.-H., He, X.-T., Liu, Y., Chen, X.-Q., & Cheong, K.-L.
- Venue
- Carbohydrate Polymers
- Publisher
- Elsevier BV
- Published
- 2020-04
- Volume
- 234
- Pages
- 115894
- ISSN
- 0144-8617 (ISSN-L)
- OpenAlex
- W3002745423
- Cited by
- 281
- References
- 52
- FWCI
- 26.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zhang, X., Aweya, J. J., Huang, Z.-X., Kang, Z.-Y., Bai, Z.-H., Li, K.-H., He, X.-T., Liu, Y., Chen, X.-Q., & Cheong, K.-L. (2020). In vitro fermentation of Gracilaria lemaneiformis sulfated polysaccharides and its agaro-oligosaccharides by human fecal inocula and its impact on microbiota. Carbohydrate Polymers. https://doi.org/10.1016/j.carbpol.2020.115894
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
