The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Myocyte apoptosis in heart failure
Abstract
Human heart failure is preceded by a process termed cardiac remodeling in which heart chambers progressively enlarge and contractile function deteriorates. Programmed cell death (apoptosis) of cardiac muscle cells has been identified as an essential process in the progression to heart failure. The execution of the apoptotic program entails complex interactions between and execution of multiple molecular subprograms. Unlike necrosis, apoptosis is an orderly regulated process and, by inference, a logical therapeutic target if intervention occurs at an early stage. To identify potential therapeutic targets, it is imperative to have a full understanding of the apoptotic pathways that are functional in the cardiac muscle. Accordingly, the present review summarizes the apoptotic pathways operative in cardiac muscle and discusses therapeutic options related to apoptosis for the future treatment of human heart failure.
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Cites
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Apoptosis in the Failing Human Heart
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Apoptosis in Myocytes in End-Stage Heart Failure
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An Induced Proximity Model for Caspase-8 Activation
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Cited by
Cardioprotective and Antiapoptotic Effects of Heme Oxygenase-1 in the Failing Heart
Wang, G., Hamid, T., Keith, R. J., Zhou, G., Partridge, C. R., Xiang, X., Kingery, J. R., Lewis, R. K., Li, Q., Rokosh, D. G., et al. (2010) · Circulation · doi:10.1161/circulationaha.109.905471 · Cited by 249
Pchejetski, D., Kunduzova, O., Dayon, A., Calise, D., Seguelas, M.-H., Leducq, N., Seif, I., Parini, A., & Cuvillier, O. (2007) · Circulation Research · doi:10.1161/01.res.0000253900.66640.34 · Cited by 195
Zhang, S., Wu, P., Liu, J., Du, Y., & Yang, Z. (2021) · Drug Design, Development and Therapy · doi:10.2147/dddt.s269029 · Cited by 32
Wei, C., Li, H., Wang, Y., Peng, X., Shao, H., Li, H., Bai, S., & Xu, C. (2016) · Experimental Biology and Medicine · doi:10.1177/1535370216643417 · Cited by 32
Metadata
- Authors
- VANEMPEL, V, BERTRAND, A., HOFSTRA, L., CRIJNS, H., DOEVENDANS, P., & DEWINDT, L.
- Venue
- Cardiovascular Research
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-07-01
- Volume
- 67
- Issue
- 1
- Pages
- 21-29
- ISSN
- 0008-6363 (ISSN-L)
- OpenAlex
- W2147145830
- Cited by
- 373
- References
- 72
- FWCI
- 4.03
- Type
- journal article
- Language
- en
- Open access
- closed
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- VANEMPEL, V, BERTRAND, A., HOFSTRA, L., CRIJNS, H., DOEVENDANS, P., & DEWINDT, L. (2005). Myocyte apoptosis in heart failure. Cardiovascular Research. https://doi.org/10.1016/j.cardiores.2005.04.012
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
