The DOI matches its Crossref record; 24 of the 24 references it cites were found in a registry or an index.
The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative
Open accessAbstract
Summary Short-chain dehydrogenases/reductases (SDR) constitute one of the largest enzyme superfamilies with presently over 46 000 members. In phylogenetic comparisons, members of this superfamily show early divergence where the majority have only low pair-wise sequence identity, although sharing common structural properties. The SDR enzymes are present in virtually all genomes investigated, and in humans over 70 SDR genes have been identified. In humans, these enzymes are involved in the metabolism of a large variety of compounds, including steroid hormones, prostaglandins, retinoids, lipids and xenobiotics. It is now clear that SDRs represent one of the oldest protein families and contribute to essential functions and interactions of all forms of life. As this field continues to grow rapidly, a systematic nomenclature is essential for future annotation and reference purposes. A functional subdivision of the SDR superfamily into at least 200 SDR families based upon hidden Markov models forms a suitable foundation for such a nomenclature system, which we present in this paper using human SDRs as examples.
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Cites
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Bateman, A. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.1.276 · Cited by 14,000
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P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature
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Short-chain dehydrogenases/reductases (SDR)
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Self-citationKavanagh, K. L., Jörnvall, H., Persson, B., & Oppermann, U. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8588-y · Cited by 908
Self-citationCritical Residues for Structure and Catalysis in Short-chain Dehydrogenases/Reductases
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Self-citationNew developments in the InterPro database
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Chapman, K., Holmes, M., & Seckl, J. (2013) · Physiological Reviews · doi:10.1152/physrev.00020.2012 · Cited by 887
Marchais-Oberwinkler, S., Henn, C., Möller, G., Klein, T., Negri, M., Oster, A., Spadaro, A., Werth, R., Wetzel, M., Xu, K., et al. (2011) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.12.013 · Cited by 216
Self-citationIntegrated view on 17beta-hydroxysteroid dehydrogenases
Moeller, G., & Adamski, J. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2008.10.040 · Cited by 214
Signatures of archaic adaptive introgression in present-day human populations
Racimo, F., Marnetto, D., & Huerta-Sánchez, E. (2016) · doi:10.1101/045237 · Cited by 200
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Metadata
- Authors
- Persson, B., Kallberg, Y., Bray, J. E., Bruford, E., Dellaporta, S. L., Favia, A. D., Duarte, R. G., Jörnvall, H., Kavanagh, K. L., Kedishvili, N., Kisiela, M., Maser, E., Mindnich, R., Orchard, S., Penning, T. M., Thornton, J. M., Adamski, J., & Oppermann, U.
- Venue
- Chemico-Biological Interactions
- Publisher
- Elsevier BV
- Published
- 2009-03
- Volume
- 178
- Issue
- 1-3
- Pages
- 94-98
- ISSN
- 0009-2797 (ISSN-L)
- OpenAlex
- W2147078478
- Cited by
- 396
- References
- 24
- FWCI
- 9.31
- Type
- journal article
- Language
- en
- Open access
- green
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- Persson, B., Kallberg, Y., Bray, J. E., Bruford, E., Dellaporta, S. L., Favia, A. D., Duarte, R. G., Jörnvall, H., Kavanagh, K. L., Kedishvili, N., Kisiela, M., Maser, E., Mindnich, R., Orchard, S., Penning, T. M., Thornton, J. M., Adamski, J., & Oppermann, U. (2009). The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. Chemico-Biological Interactions. https://doi.org/10.1016/j.cbi.2008.10.040
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