Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities
Davis, Ryan J., Welcker, Markus, Clurman, Bruce E.·2014·Cancer Cell
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- FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cellsScarlett Y. Yang, Katharina E. Hayer, Hossein Fazelinia, Lynn A. Spruce, Mukta Asnani, Kathryn L. Black, Ammar S. Naqvi, Vinodh Pillai, Yoseph Barash, Kojo S.J. Elenitoba‐Johnson et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Characterization of F-box proteins and their target substrates in cancerHwee‐Fang Ng · 2014 · Figshare
- HSF Supports CancerMakoto Chuma · 2016 · Springer eBooks
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- FBXW7 Pathway Functions as a Promising Therapeutic Target of CholangiocarcinomaHui Yang, Lili Chen · 2016 · Chemotherapy Open access
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- Targeting the Ubiquitin-Dependent Transcriptional and Epigenetic Landscape in CancerEmily Avitan‐Hersh, Amir Orian · 2017 · Current Pharmacology Reports
- The Molecular Pathology of Serous Endometrial CancerMary Ellen Urick, Meghan L. Rudd, Daphne W. Bell · 2017 · Molecular pathology library
- Genetic alterations in Adult T cell leukemiaChien‐Hung Yeh · 2017 · KU ScholarWorks (The University of Kansas)
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- c-Myc Metabolic Addiction in Cancers Counteracted by Resveratrol and NQO2Tze‐chen Hsieh, Barbara B. Doonan, JOSEPH M. WU · 2019 · IntechOpen eBooks
- E3-mediated Ubiquitin and Ubiquitin-like Protein Ligation: Mechanisms and Chemical ProbesDavid T. Krist, Brenda Arlene Schulman · 2020 · Royal Society of Chemistry eBooks
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- Comprehensive Study of Human FBXW7 Deleterious nsSNP's Functional Inference and Susceptibility to Gynaecological CancerArchana vasuki, Jemmy Christy · 2021 · Research Square
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- Data from Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to RadiationZhuo Yang, Nan Hu, Weiwei Wang, Weihua Hu, Shaolong Zhou, Jianxiang Shi, Minghe Li, Zhou Jing, Chao Chen, Xuyang Zhang et al. · 2023
- Loss of the cyclin kinase inhibitor p27kip1 opens a therapeutic window by deregulating pathway choice after DNA double strand breaksNisar P. Malek, Przemyslaw M. Bozko, Khắc Cường Bùi, Mohammad Rahbari, Sven Mattern, Pavlos Missios, Mihály Sulyok, Maria Garcia Beccaria, Mirian Fernandez, Stephanie K. Roessler et al. · 2023 · Research Square
- Recurrent FBXW7 mutations bypass Wnt/β-catenin addiction in cancerZheng Zhong, David M. Virshup · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Nephronophthisis-associated FBW7 mediates cyst-dependent decline of renal function in ADPKDMaulin Mukeshchandra Patel, Vasileios Gerakopoulos, Eleni Petsouki, Kurt A. Zimmerman, Leonidas Tsiokas · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- MAPK dependent regulation of FBXW7 phosphodegronsNeha Singh · 2023 · Eötvös Loránd Tudományegyetem
- Proteomic Changes Associated With Endogenous FBXW7 Mutations in Moderately Differentiated Endometrial Cancer Cells Include Increased TROP2 and Galectin‐3 LevelsMary Ellen Urick, Suresh Kumar Chalapareddy, Eun‐Jeong Yu, Daphne W. Bell · 2025 · Cancer Medicine
- Nuclear shuttling of CDC4 mediated broad-spectrum antiviral activity against diverse coronavirusesMingwei Li, Yang Wu, Jin Tian, Qian Yang, Mingze Gao, Yongrui Wang, Xuepeng Wang, Ju Zhang, Yudi Pan, Hongyan Shi et al. · 2025 · Emerging Microbes & Infections
- Additional file 1 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticityJuntae Kwon, Zhang, Jinmin, Boram Mok, Samuel Allsup, Kim, Chul, Toretsky, Jeffrey, Cecil Han · 2023 · Figshare
- Additional file 1 of METTL3-mediated m6A mRNA modification of FBXW7 suppresses lung adenocarcinomaWu, Yingtong, Chang, Ning, Zhang, Yong, Zhang, Xinxin, Leidi Xu, Yinggang Che, Qiao, Tianyun, Wu, Bin, Zhou, Ying, Jiang, Jun et al. · 2021 · Figshare
- Additional file 2 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticityJuntae Kwon, Zhang, Jinmin, Boram Mok, Samuel Allsup, Kim, Chul, Toretsky, Jeffrey, Cecil Han · 2024 · Figshare
- Additional file 3 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticityJuntae Kwon, Zhang, Jinmin, Boram Mok, Samuel Allsup, Kim, Chul, Toretsky, Jeffrey, Cecil Han · 2024 · Figshare
- Additional file 4 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticityJuntae Kwon, Zhang, Jinmin, Boram Mok, Samuel Allsup, Kim, Chul, Toretsky, Jeffrey, Cecil Han · 2024 · Figshare
- Additional file 5 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticityJuntae Kwon, Zhang, Jinmin, Boram Mok, Samuel Allsup, Kim, Chul, Toretsky, Jeffrey, Cecil Han · 2024 · Figshare
- Additional file 2 of METTL3-mediated m6A mRNA modification of FBXW7 suppresses lung adenocarcinomaWu, Yingtong, Chang, Ning, Zhang, Yong, Zhang, Xinxin, Leidi Xu, Yinggang Che, Qiao, Tianyun, Wu, Bin, Zhou, Ying, Jiang, Jun et al. · 2021 · Figshare
- CRISPR-enabled genetic screens identify synthetic lethal targets across frequently altered cancer driversJessica Desjardins, Julian Bowlan, Cynthia Bernier, Srishti Jain, Théo Goullet de Rugy, David Gallo, Mark E. Orcholski, Nancy Laterreur, Abira Rajah, Joshua Miller et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
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- Multi-omics analysis identifies FBXW7 downregulation in hypertensive aorta with experimental validationQiang Zhao, Ruixue Guo, Xuemei Fan, Jie Xu, Pengchong Dong, Shasha Gong, Ruiqin Xie, Libo Su, Jidong Zhang · 2026 · Journal of Radiation Research and Applied Sciences
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- SND1 promotes colorectal cancer progression and metastasis by stabilizing HK2 through the inhibition of FBW7-mediated ubiquitinationHaoran Zhang, Jinlin Nie, Na Li, Zhen Bao, Tianjie Chen, Yong Yang, Hailiang Li · 2026 · International Immunopharmacology
- Recalibrating the apoptotic threshold: Ubiquitin‐regulated ER stress signalling in colorectal cancerJing Hu, Shanliang Zheng, Ying Hu · 2026 · Clinical and Translational Discovery
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