Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities

Davis, Ryan J., Welcker, Markus, Clurman, Bruce E.·2014·Cancer Cell

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    Scarlett Y. Yang, Katharina E. Hayer, Hossein Fazelinia, Lynn A. Spruce, Mukta Asnani, Kathryn L. Black, Ammar S. Naqvi, Vinodh Pillai, Yoseph Barash, Kojo S.J. Elenitoba‐Johnson et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  7. Characterization of F-box proteins and their target substrates in cancer
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  8. HSF Supports Cancer
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  9. Are Micrornas the Answer to Colorectal Cancer’s Big Questions?
    Anne E Sarver Subbaya · 2015 · Journal of Clinical & Experimental Pathology
  10. FBXW7 Pathway Functions as a Promising Therapeutic Target of Cholangiocarcinoma
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  11. A Drosophila melanogaster poszt-meiotikus spermatogenezisében szerepet játszó gének vizsgálata
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  14. Genetic alterations in Adult T cell leukemia
    Chien‐Hung Yeh · 2017 · KU ScholarWorks (The University of Kansas)
  15. Cooperating Oncogenic Alterations in Aggressive Pten-Deficient Breast Cancer
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  16. c-Myc Metabolic Addiction in Cancers Counteracted by Resveratrol and NQO2
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  17. E3-mediated Ubiquitin and Ubiquitin-like Protein Ligation: Mechanisms and Chemical Probes
    David T. Krist, Brenda Arlene Schulman · 2020 · Royal Society of Chemistry eBooks
  18. LSD1 Destabilizes FBXW7 Independent of Its Demethylase Activity
    Huiyin Lan, Mingjia Tan, Qiang Zhang, Fei Yang, Hua Li, Xiufang Xiong, Yi Sun · 2018 · SSRN Electronic Journal
  19. Comprehensive Study of Human FBXW7 Deleterious nsSNP's Functional Inference and Susceptibility to Gynaecological Cancer
    Archana vasuki, Jemmy Christy · 2021 · Research Square
  20. FBXW7 triggers degradation of WDR5 to prevent mitotic slippage
    Simon Hänle-Kreidler, Kai T. Richter, Ingrid Hoffmann · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Data from Loss of FBXW7 Correlates with Increased IDH1 Expression in Glioma and Enhances IDH1-Mutant Cancer Cell Sensitivity to Radiation
    Zhuo Yang, Nan Hu, Weiwei Wang, Weihua Hu, Shaolong Zhou, Jianxiang Shi, Minghe Li, Zhou Jing, Chao Chen, Xuyang Zhang et al. · 2023
  22. Loss of the cyclin kinase inhibitor p27kip1 opens a therapeutic window by deregulating pathway choice after DNA double strand breaks
    Nisar P. Malek, Przemyslaw M. Bozko, Khắc Cường Bùi, Mohammad Rahbari, Sven Mattern, Pavlos Missios, Mihály Sulyok, Maria Garcia Beccaria, Mirian Fernandez, Stephanie K. Roessler et al. · 2023 · Research Square
  23. Recurrent FBXW7 mutations bypass Wnt/β-catenin addiction in cancer
    Zheng Zhong, David M. Virshup · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  24. Nephronophthisis-associated FBW7 mediates cyst-dependent decline of renal function in ADPKD
    Maulin Mukeshchandra Patel, Vasileios Gerakopoulos, Eleni Petsouki, Kurt A. Zimmerman, Leonidas Tsiokas · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  25. MAPK dependent regulation of FBXW7 phosphodegrons
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  26. Proteomic Changes Associated With Endogenous FBXW7 Mutations in Moderately Differentiated Endometrial Cancer Cells Include Increased TROP2 and Galectin‐3 Levels
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  28. Additional file 1 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity
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  29. Additional file 1 of METTL3-mediated m6A mRNA modification of FBXW7 suppresses lung adenocarcinoma
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  31. Additional file 3 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity
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  32. Additional file 4 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity
    Juntae Kwon, Zhang, Jinmin, Boram Mok, Samuel Allsup, Kim, Chul, Toretsky, Jeffrey, Cecil Han · 2024 · Figshare
  33. Additional file 5 of USP13 drives lung squamous cell carcinoma by switching lung club cell lineage plasticity
    Juntae Kwon, Zhang, Jinmin, Boram Mok, Samuel Allsup, Kim, Chul, Toretsky, Jeffrey, Cecil Han · 2024 · Figshare
  34. Additional file 2 of METTL3-mediated m6A mRNA modification of FBXW7 suppresses lung adenocarcinoma
    Wu, Yingtong, Chang, Ning, Zhang, Yong, Zhang, Xinxin, Leidi Xu, Yinggang Che, Qiao, Tianyun, Wu, Bin, Zhou, Ying, Jiang, Jun et al. · 2021 · Figshare
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  42. Genome-wide CRISPR screens map synthetic lethal interactions across recurrent cancer driver alterations
    Jessica Desjardins, Julian Bowlan, Cynthia Bernier, Srishti Jain, Théo Goullet de Rugy, David Gallo, Mark E. Orcholski, Nancy Laterreur, Abira Rajah, Joshua Miller et al. · 2026 · Cell Reports
  43. SND1 promotes colorectal cancer progression and metastasis by stabilizing HK2 through the inhibition of FBW7-mediated ubiquitination
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  44. Recalibrating the apoptotic threshold: Ubiquitin‐regulated ER stress signalling in colorectal cancer
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  45. Ubiquitin signaling in tumor-associated macrophage reprogramming: mechanisms and therapeutic opportunities in cancers
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  46. BindingDB Entry 50018524: Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer.
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