In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals targeting opportunities

Rubio-Perez, Carlota, Tamborero, David, Schroeder, Michael P., Antolín, Albert A., Deu-Pons, Jordi, Perez-Llamas, Christian, Mestres, Jordi, Gonzalez-Perez, Abel +1 more·2015·Cancer Cell

DOI 10.1016/j.ccell.2015.02.007

Cited by (295)

Items 101–200 of 295

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Charles A. Blatti, Amin Emad, Matthew J. Berry, Lisa Gatzke, Milt Epstein, Daniel Lanier, Pramod Rizal, Jing Ge, Xiaoxia Liao, Omar T. Sobh et al. · 2020 · PLoS Biology
CTCF maintains regulatory homeostasis of cancer pathways
Sarah J. Aitken, Ximena Ibarra-Soria, Elissavet Kentepozidou, Paul Flicek, Christine Feig, John C. Marioni, Duncan T. Odom · 2018 · Genome biology
Dynamic host immune response in virus-associated cancers
Song Cao, Kristine M. Wylie, Matthew A. Wyczalkowski, Alla Y. Karpova, Jessica C. Ley, Sam Q. Sun, R. Jay Mashl, Wen-Wei Liang, Xiaowei Wang, Kimberly J. Johnson et al. · 2019 · Communications Biology
Systematic illumination of druggable genes in cancer genomes
Junjie Jiang, Jiao Yuan, Zhongyi Hu, Youyou Zhang, Tianli Zhang, Mu Xu, Meixiao Long, Yi Fan, Janos Laszlo Tanyi, Kathleen T. Montone et al. · 2022 · Cell Reports
Proof-of-Concept Workflow for Establishing Reference Intervals of Human Urine Proteome for Monitoring Physiological and Pathological Changes
Wenchuan Leng, Xiaotian Ni, Changqing Sun, Tianyuan Lu, Anna Malovannaya, Sung Yun Jung, Yin Huang, Yang Qiu, Guannan Sun, Matthew Valle Holt et al. · 2017 · EBioMedicine
An Improved Method for Prediction of Cancer Prognosis by Network Learning
Minseon Kim, Ilhwan Oh, Jaegyoon Ahn · 2018 · Genes
GUILDify v2.0: A Tool to Identify Molecular Networks Underlying Human Diseases, Their Comorbidities and Their Druggable Targets
Joaquim Aguirre‐Plans, Janet Piñero, Ferrán Sanz, Laura Ines Furlong, Narcís Fernández‐Fuentes, Baldomero Oliva, Emre Güney · 2019 · Journal of Molecular Biology
A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patients
Zhu, Xiaoqiang, Tian, Xianglong, Ji, Linhua, Zhang, Xinyu, Cao, Yingying, Shen, Chaoqin, Hu, Ye, Wong, Jason W. H., Fang, Jing-Yuan, Hong, Jie et al. · 2021 · npj Precision Oncology
Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models
Antonina Mitrofanova, Àlvaro Aytés, Min Zou, Michael M. Shen, Cory T. Abate-Shen, Andrea Califano · 2015 · Cell Reports
Challenges in identifying cancer genes by analysis of exome sequencing data
Matan Hofree, Hannah K. Carter, Jason F. Kreisberg, Sourav Bandyopadhyay, Paul S. Mischel, Stephen Henry Friend, Trey Ideker · 2016 · Nature Communications
Detecting similar binding pockets to enable systems polypharmacology
Miquel Duran‐Frigola, Lydia Siragusa, Eytan Ruppin, Xavier Barril, Gabriele Cruciani, Patrick Aloy · 2017 · PLoS Computational Biology
Beyond Synthetic Lethality: Charting the Landscape of Pairwise Gene Expression States Associated with Survival in Cancer
Assaf Magen, Avinash D Sahu, Joo Sang Lee, Mahfuza Sharmin, Alexander Lugo, Jorge Silvio Gutkind, Alejandro A. Schäffer, Eytan Ruppin, Sridhar S. Hannenhalli · 2019 · Cell Reports
Identification of Coding and Long Noncoding RNAs Differentially Expressed in Tumors and Preferentially Expressed in Healthy Tissues
Juan Pablo Unfried, Guillermo Serrano, Beatriz Suárez, Paloma Sangro, Valeria Ferretti, Celia Prior, Loreto Boix, Jordi Bruix, Bruno Sangro, Víctor Segura et al. · 2019 · Cancer Research
A New View of Activating Mutations in Cancer
Ruth Nussinov, Chung‐Jung Tsai, Hyunbum Jang · 2022 · Cancer Research
Uncovering disease mechanisms through network biology in the era of Next Generation Sequencing
Janet Piñero, Ariel José Berenstein, Abel González-Pérez, Ariel Chernomoretz, Laura Ines Furlong · 2016 · Scientific Reports
Transcriptional response profiles of paired tumor-normal samples offer novel perspectives in pan-cancer analysis
Shuofeng Hu, Hanyu Yuan, Zongcheng Li, Jian Zhang, Jiaqi Wu, Yaowen Chen, Qiang Shi, Wu Ren, Ningsheng Shao, Xiaomin Ying · 2017 · Oncotarget
Systematic discovery of the functional impact of somatic genome alterations in individual tumors through tumor-specific causal inference
Chunhui Cai, Gregory F. Cooper, Kevin N. Lu, Xiaojun Ma, Shuping Xu, Zhenlong Zhao, Xueer Chen, Yifan Xue, Adrian V. Lee, Nathan L Clark et al. · 2019 · PLoS Computational Biology
Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma
Ana C. deCarvalho, Hoon Kim, Laila Poisson, Mary E. Winn, Claudius Mueller, David Cherba, Julie M. Koeman, Sahil Seth, Alexei I. Protopopov, Michelle Madden Felicella et al. · 2016 · bioRxiv (Cold Spring Harbor Laboratory)
G2Vec: Distributed gene representations for identification of cancer prognostic genes
Jonghwan Choi, Ilhwan Oh, Sangmin Seo, Jaegyoon Ahn · 2018 · Scientific Reports
Systematically Characterizing A-to-I RNA Editing Neoantigens in Cancer
Chi Zhou, Zhiting Wei, Liye Zhang, Zhaoyi Yang, Qi Liu · 2020 · Frontiers in Oncology
Performance comparison of two commercial human whole-exome capture systems on formalin-fixed paraffin-embedded lung adenocarcinoma samples
Silvia Bonfiglio, Irene Vanni, Valeria Rossella, Anna Truini, Dejan Lazarević, Maria Giovanna Dal Bello, Angela Alama, Marco Mora, Erika Rijavec, Carlo Genova et al. · 2016 · BMC Cancer
State of Art of Cancer Pharmacogenomics in Latin American Populations
Andrés López‐Cortés, Santiago Xavier Guerrero, María Ana Redal, Ángel T. Alvarado, Luis A. Quiñones · 2017 · International Journal of Molecular Sciences
Pathway-based dissection of the genomic heterogeneity of cancer hallmarks’ acquisition with SLAPenrich
Francesco Iorio, Luz García‐Alonso, Jonathan S. Brammeld, Iñigo Martincorena, David R. Willé, Ultan McDermott, Julio Sáez-Rodríguez · 2018 · Scientific Reports
Bioinformatics roadmap for therapy selection in cancer genomics
María José Jiménez‐Santos, Santiago García‐Martín, Coral Fustero Torre, Tomás Di Domenico, Gonzalo Goméz-López, Fátima Al‐Shahrour · 2022 · Molecular Oncology
Nanotheranostics for Diagnosis and Treatment of Breast Cancer
Parth C. Patel, Kishore Kumar, Vineet Kumar Jain, Harvinder Popli, Awesh Kumar Yadav, Keerti Jain · 2023 · Current Pharmaceutical Design
Upregulation of nucleoprotein AHNAK is associated with poor outcome of pancreatic ductal adenocarcinoma prognosis via mediating epithelial-mesenchymal transition
Zhiwen Zhang, Xiaoding Liu, Rui Huang, Xuguang Liu, Zhiyong Liang, Tonghua Liu · 2019 · Journal of Cancer
Genomic landscape of endometrial stromal sarcoma of uterus
Youn Jin Choi, Seung‐Hyun Jung, Min Sung Kim, In-Pyo Baek, Jae-Keun Rhee, Sung Hak Lee, Soo Young Hur, Tae‐Min Kim, Yeun‐Jun Chung, Sug Hyung Lee · 2015 · Oncotarget
Computational methods and resources for the interpretation of genomic variants in cancer
Rui Tian, Malay Kumar Basu, Emidio Capriotti · 2015 · BMC Genomics
Pharmacogenomics, biomarker network, and allele frequencies in colorectal cancer
Andrés López‐Cortés, César Paz‐y‐Miño, Santiago Xavier Guerrero, Gabriela Jaramillo-Koupermann, Ángela León Cáceres, Dámaris P. Intriago-Baldeón, Jennyfer M. García-Cárdenas, Patricia Guevara‐Ramírez, Isaac Armendáriz‐Castillo, Paola Leone et al. · 2019 · The Pharmacogenomics Journal
Comprehensive Genomic Profiling of Patient-matched Head and Neck Cancer Cells: A Preclinical Pipeline for Metastatic and Recurrent Disease
Lluís Nisa, David Barras, Michaela Medová, Daniel M. Aebersold, Matúš Medo, Michaela Poliaková Turan, Jonas P. Koch, Beat Bojaxhiu, Olgun Eliçin, Matthias S. Dettmer et al. · 2018 · Molecular Cancer Research
In silico learning of tumor evolution through mutational time series
Noam Auslander, Yuri I. Wolf, Eugene V. Koonin · 2019 · Proceedings of the National Academy of Sciences
Whole-exome sequencing identified mutational profiles of high-grade colon adenomas
Sung Hak Lee, Seung Hyun Jung, Tae-Min Kim, Je‐Keun Rhee, Hyeon‐Chun Park, Sung Soo Kim, Sung Soo Kim, Chang Hyeok An, Sug Hyung Lee, Yeun‐Jun Chung · 2016 · Oncotarget
Using Pharmacogenomic Databases for Discovering Patient-Target Genes and Small Molecule Candidates to Cancer Therapy
José Ernesto Belizário, Beatriz A. Sangiuliano, Marcela Pérez-Sosa, Jennifer M. Neyra, Dayson Moreira · 2016 · Frontiers in Pharmacology
Clonality, Heterogeneity, and Evolution of Synchronous Bilateral Ovarian Cancer
Xia Yin, Ying Jing, Mei‐Chun Cai, Pengfei Ma, Yi Zhang, Cong Xu, Meiying Zhang, Wen J. Di, Guanglei Zhuang · 2017 · Cancer Research
Next Generation Sequencing in Non-Small Cell Lung Cancer: Pitfalls and Opportunities
Chiara Lazzari, Alessandra Bulotta, Maria Giulia Cangi, Gabriele Bucci, Lorenza Pecciarini, Silvia Bonfiglio, Vincenza Lorusso, Stefania Ippati, Gianluigi Arrigoni, Greta Grassini et al. · 2020 · Diagnostics
CD44v8-10 as a potential theranostic biomarker for targeting disseminated cancer cells in advanced gastric cancer
Eun Seok Choi, Hyunjin Kim, Hyoung‐Pyo Kim, Yongdoo Choi, Sung‐Ho Goh · 2017 · Scientific Reports
Matrine Is Identified as a Novel Macropinocytosis Inducer by a Network Target Approach
Bo Zhang, Xin Wang, Yan Li, Min Huan Wu, Shuyan Wang, Shao Li · 2018 · Frontiers in Pharmacology
Continuous culture of urine-derived bladder cancer cells for precision medicine
Shuai Jiang, Jiaqi Wang, Yang Chen, Renke Tan, Jun Hou, Yuan Shi, Huihui Zhang, Shiyu Ma, Jianan Wang, Mengmeng Zhang et al. · 2019 · Protein & Cell
Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers
J. Sa, J. Hwang, Y. Cho, Ji-Yoon Ryu, Jung-Joo Choi, S. Jeong, Jihye Kim, M. Kim, E. Paik, Y. Lee et al. · 2019 · Genome Biology
In Silico Analysis Guides Selection of BET Inhibitors for Triple-Negative Breast Cancer Treatment
Javier Pérez‐Peña, Gemma Serrano‐Heras, Juan Carlos Montero, Verónica Corrales‐Sánchez, Atanasio Pandiella, Alberto Ocaña · 2016 · Molecular Cancer Therapeutics
Overexpression of endothelin B receptor in glioblastoma: a prognostic marker and therapeutic target?
Suhas V. Vasaikar, Giorgos Tsipras, Natalia Landázuri, Helena Costa, Vanessa Wilhelmi, Patrick Scicluna, Huanhuan Cui, Abdul‐Aleem Mohammad, Belghis Davoudi, Ming-Mei Shang et al. · 2018 · BMC Cancer
Integrative omics analyses broaden treatment targets in human cancer
Sohini Sengupta, Sam Q. Sun, Kuan‐lin Huang, Clara Oh, Matthew H. Bailey, Rajees Varghese, Matthew A. Wyczalkowski, Jie Ning, Piyush Tripathi, Joshua F. McMichael et al. · 2018 · Genome Medicine
Benchmarking of spatial transcriptomics platforms across six cancer types
Sergi Cervilla, Daniela Grases, Elena Perez, Francisco X. Real, Eva Musulén, Julieta Aprea, Manel Esteller, Eduard Porta‐Pardo · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
ConsensusDriver Improves upon Individual Algorithms for Predicting Driver Alterations in Different Cancer Types and Individual Patients
Denis Bertrand, Sibyl Drissler, Burton Kuan Hui Chia, Jia Yu Koh, Chenhao Li, Chayaporn Suphavilai, Iain Beehuat Tan, Niranjan Nagarajan · 2017 · Cancer Research
Chasing the FOXO3: Insights into Its New Mitochondrial Lair in Colorectal Cancer Landscape
Valentina Grossi, Candida Fasano, Valentina Celestini, Martina Lepore Signorile, Paola Sanese, Cristiano Simone · 2019 · Cancers
Dynamic clonal remodelling in breast cancer metastases is associated with subtype conversion
Ana M. Lluch, Ana Maria Gonzalez-Angulo, David Casadevall, Agda Karina Eterovic, Eduardo Martínez de Dueñas, Xiaofeng Zheng, Ángel Guerrero Zotano, Shuying Liu, Ramón M. Pérez, Ken Chen et al. · 2019 · European Journal of Cancer
Extrachromosomal Circular DNA: A New Target in Cancer
Pan Wu, Yuhang Liu, Ruijia Zhou, Lingyun Liu, Hongli Zeng, Fang Xiong, Shanshan Zhang, Zhaojian Gong, Wenling Zhang, Can Jie Guo et al. · 2022 · Frontiers in Oncology
Article Commentary: Predictive Modeling of Drug Treatment in the Area of Personalized Medicine
Lesley Ann Ogilvie, Christoph Wierling, Thomas Kessler, Hans Rudolf Lehrach, Bodo M. H. Lange · 2015 · Cancer Informatics
Beyond the limitation of targeted therapy: Improve the application of targeted drugs combining genomic data with machine learning
Rui Miao, Hao-Heng Chen, Qi Dang, Liang-Yong Xia, Ziyi Yang, Minfan He, Zhifeng Hao, Yong Liang · 2020 · Pharmacological Research
Data mining for mutation-specific targets in acute myeloid leukemia
Brooks A. Benard, Andrew J. Gentles, Thomas Köhnke, Ravindra Majeti, Danièl Thomas · 2019 · Leukemia
Resources for Interpreting Variants in Precision Genomic Oncology Applications
Hsinyi Tsang, KanakaDurga Addepalli, Sean R. Davis · 2017 · Frontiers in Oncology
Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns
Lídia Mateo, Miquel Duran‐Frigola, Albert Gris‐Oliver, Marta Palafox, Maurizio Scaltriti, Pedram Razavi, Sarat Chandarlapaty, Joaquı́n Arribas, Meritxell Bellet, Violeta Serra et al. · 2020 · Genome Medicine
TP53_PROF: a machine learning model to predict impact of missense mutations in TP53
Gil Ben Cohen, Flora Doffe, Michal Devir, Bernard Leroy, Thierry Soussi, Shai Rosenberg · 2021 · Briefings in Bioinformatics
Tumour mutations in long noncoding RNAs enhance cell fitness
R. Esposito, Andrés Lanzós, Tina Uroda, S. Ramnarayanan, I. Büchi, Taisia Polidori, Hugo A. Guillen-Ramirez, Ante Mihaljević, Bernard Merlin, Lia Mela et al. · 2021 · bioRxiv
Long-range gene regulation in hormone-dependent cancer
Theophilus T. Tettey, Lorenzo Rinaldi, Gordon L. Hager · 2023 · Nature reviews. Cancer
Tumor cell heterogeneity and resistance; report from the 2018 Coffey‐Holden Prostate Cancer Academy Meeting
Andrea K. Miyahira, Robert Benjamin Den, Maria Isabel Carlo, Renée de Leeuw, Thomas A. Hope, Fatima H. Karzai, Rana R. McKay, Simpa Samuel Salami, Jonathan W. Simons, Kenneth J. Pienta et al. · 2018 · The Prostate
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Jacob Edogbanya, Daniela Tejada-Martínez, Nigel J. Jones, Amit Jaiswal, Sarah Bell, Rui Cordeiro, Sipko van Dam, Daniel John Rigden, João Pedro de Magalhães · 2021 · Cellular and Molecular Life Sciences
The cancer proteomic landscape and the HUPO Cancer Proteome Project
Connie R. Jiménez, Hui Zhang, Christopher R. Kinsinger, Edouard Collins Nice · 2018 · Clinical Proteomics
Differential networking meta-analysis of gastric cancer across Asian and American racial groups
Wentao Dai, Quanxue Li, Bingya Liu, Yixue Li, Yuanyuan Li · 2018 · BMC Systems Biology
Medicinal Importance of Azo and Hippuric Acid Derivatives
Tehreem Tahir, Muhammad Haroon Ashfaq, Humna Asghar, Mirza Imran Shahzad, Rukhsana Tabassum, Areeba Ashfaq · 2019 · Mini-Reviews in Medicinal Chemistry
DECO: decompose heterogeneous population cohorts for patient stratification and discovery of sample biomarkers using omic data profiling
Francisco Jose Campos-Laborie, Alberto Risueño, María Ortiz-Estévez, Beatriz Rosón, C Droste, Celia Fontanillo, R Loos, José Manuel Sánchez-Santos, Matthew W. B. Trotter, Javier De Las Rivas · 2019 · Bioinformatics
Genotyping of Circulating Tumor DNA Reveals the Clinically Actionable Mutation Landscape of Advanced Colorectal Cancer
Weiguo Cao, Yaping Xu, Lianpeng Chang, Yuhua Gong, Li Li, Xianwei Mo, Xin Zhang, Guole Lin, Jiaolin Zhou, Dan Liu et al. · 2019 · Molecular Cancer Therapeutics
Identification of driver copy number alterations in diverse cancer types and application in drug repositioning
Wenbin Zhou, Zhangxiang Zhao, Ruiping Wang, Yue Han, Chengyu Wang, Fan Yang, Ya Han, Haihai Liang, Lishuang Qi, Chenguang Wang et al. · 2017 · Molecular Oncology
PanDrugs2: prioritizing cancer therapies using integrated individual multi-omics data
María José Jiménez‐Santos, Alba Nogueira-Rodríguez, Elena Piñeiro-Yáñez, Hugo López-Fernández, Santiago García‐Martín, Paula Gómez-Plana, Miguel Reboiro‐Jato, Gonzalo Goméz-López, Daniel Glez‐Peña, Fátima Al‐Shahrour · 2023 · Nucleic Acids Research
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Ekaterina A. Kotelnikova, Mikhail A. Pyatnitskiy, A. G. Paleeva, Olga S. Kremenetskaya, D. V. Vinogradov · 2016 · Oncotarget
Deep sequencing of human papillomavirus positive loco-regionally advanced oropharyngeal squamous cell carcinomas reveals novel mutational signature
Christian Grønhøj, David Hebbelstrup Jensen, Tina Klitmøller Agander, Katalin Kiss, Estrid Vilma Solyom Høgdall, Lena Specht, Frederik Otzen Bagger, Finn Cilius Nielsen, Christian von Buchwald · 2018 · BMC Cancer
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Sergi Cervilla, Daniela Grases Mendoza, Elena Perez, Francisco X. Real, Eva Musulén, Julieta Aprea, Manel Esteller, Eduard Porta‐Pardo · 2026 · Genome biology
Regulated Phosphosignaling Associated with Breast Cancer Subtypes and Druggability*
Kuan-lin Huang, Yige Wu, Tina M. Primeau, Yi-Ting Wang, Yuqian Gao, Joshua F. McMichael, Adam David Scott, Song Cao, Michael C. Wendl, Kimberly J. Johnson et al. · 2019 · Molecular & Cellular Proteomics
Whole-Exome Sequencing Characterized the Landscape of Somatic Mutations and Pathways in Colorectal Cancer Liver Metastasis
Liuxing Feng, Shifu Hong, Jin Gao, Jiayi Li · 2019 · Journal of Oncology
In silico approaches for drug repurposing in oncology: a scoping review
Bruno Raphael Ribeiro Cavalcante, Raíza Dias Freitas, Leonardo de Oliveira Siquara da Rocha, Roberto de Souza Batista dos Santos, Bruno Solano de Freitas Souza, Pablo Ivan Pereira Ramos, Gisele Vieira Rocha, Clarissa Araújo Gurgel Rocha · 2024 · Frontiers in Pharmacology
Analysis of mutation, selection, and epistasis: an informed approach to cancer clinical trials
Jon F. Wilkins, Vincent L. Cannataro, Brian Shuch, Jeffrey P. Townsend · 2018 · Oncotarget
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Yeongjun Jang, Taekjin Choi, Jong-Ho Kim, Jisub Park, Jihae Seo, Sangok Kim, Yeajee Kwon, Seungjae Lee, Sanghyuk Lee · 2018 · BMC Medical Genomics
A Middle-Out Modeling Strategy to Extend a Colon Cancer Logical Model Improves Drug Synergy Predictions in Epithelial-Derived Cancer Cell Lines
Eirini Tsirvouli, Vasundra Touré, Barbara Niederdorfer, Miguél Vázquez, Åsmund Flobak, Martin T. R. Kuiper · 2020 · Frontiers in Molecular Biosciences
Solving Mazes of Organelle‐Targeted Therapies with DNA Nanomachines
Muhammad Umar Farooq, Charles Henderson Lawrie, Nan‐Nan Deng · 2025 · Advanced Materials
Towards Post-Genomic Oncology: Embracing Cancer Complexity via Artificial Intelligence, Multi-Targeted Therapeutics, Drug Repurposing, and Innovative Study Designs
Annabella Di Mauro, Massimiliano Berretta, Mariachiara Santorsola, Gerardo Ferrara, Carmine Picone, Giovanni Savarese, Alessandro Ottaiano · 2025 · International Journal of Molecular Sciences
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Thiemo Florin Dinger, Oleg Chen, Claudia Dittfeld, Lydia Hetze, Melanie Hüther, Marit Wondrak, Steffen Löck, Wolfgang Eicheler, Georg Breier, Leoni A. Kunz‐Schughart · 2020 · Theranostics
Pan-cancer proteogenomic investigations identify post-transcriptional kinase targets
Abdülkadir Elmas, Serena Tharakan, Suraj K. Jaladanki, Matthew D. Galsky, Tao Liu, Kuan‐lin Huang · 2021 · Communications Biology
Identification of potentially oncogenic alterations from tumor-only samples reveals Fanconi anemia pathway mutations in bladder carcinomas
Chioma J. Madubata, Alireza Roshan-ghias A, Timothy H. Chu, Samuel J. Resnick, Junfei Zhao, Luís Arnes, Jiguang Wang, Raúl Rabadán · 2017 · npj Genomic Medicine
Integrating Open Data on Cancer in Support to Tumor Growth Analysis
Fleur Jeanquartier, Claire Jean-Quartier, Tobias Schreck, David Cemernek, Andreas Holzinger · 2016 · Lecture notes in computer science
Inference of Phenotype-Relevant Transcriptional Regulatory Networks Elucidates Cancer Type-Specific Regulatory Mechanisms in a Pan-Cancer Study
Amin Emad, Saurabh Sinha · 2018 · npj Systems Biology and Applications
Scan_Tcga Tools for Integrated Epigenomic and Transcriptomic Analysis of Tumor Subgroups
Aniruddha Chatterjee, Peter A. Stockwell, Euan James Rodger, Matthew F. Parry, Michael Roger Eccles · 2016 · Epigenomics
Signaling pathway profiling using reverse-phase protein array and its clinical applications
Mari Masuda, Tesshi Yamada · 2017 · Expert Review of Proteomics
Phosphoprotein Biosensors for Monitoring Pathological Protein Structural Changes
Mostak Ahmed, Kevin M. Koo, Paul N. Mainwaring, Laura G. Carrascosa, Matt Trau · 2019 · Trends in biotechnology
Improved Prediction of Cancer Outcome Using Graph-Embedded Generative Adversarial Networks
Chihyun Park, Ilhwan Oh, Jonghwan Choi, Soohyun Ko, Jaegyoon Ahn · 2021 · IEEE Access
Neutral Theory in Cancer Cell Population Genetics
Atsushi Niida, Watal M. Iwasaki, Hideki Innan · 2018 · Molecular Biology and Evolution
Distinct roles of structure-specific endonucleases EEPD1 and Metnase in replication stress responses
Neelam Sharma, Michael Clayton Speed, Chris Allen, David G. Maranon, Elizabeth A. Williamson, Sudha Singh, Robert Hromas, Jac A. Nickoloff · 2020 · NAR Cancer
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Sameea Ahmed Khan, Rajesh Sharma · 2022 · Current Drug Delivery
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Poojitha Ojamies, Mika Kontro, Henrik Edgren, Pekka Ellonen, Sonja Lagström, Henrikki Almusa, T Miettinen, Samuli Eldfors, David Tamborero, Krister Wennerberg et al. · 2016 · Leukemia
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Bhagwan Yadav, Peddinti V. Gopalacharyulu, Tea Pemovska, Suleiman A. Khan, Agnieszka Szwajda, Jing Ping Tang, Krister Wennerberg, Tero A. Aittokallio · 2015 · Disease Models & Mechanisms
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Miquel Duran‐Frigola, Lídia Mateo, Patrick Aloy · 2017 · Current Opinion in Systems Biology
Identification of cis-regulatory mutations generating de novo edges in personalized cancer gene regulatory networks
Zeynep Kalender Atak, Hana Imrichová, Dmitry Svetlichnyy, Gert J. Hulselmans, Valerie Christiaens, Joke Reumers, Hugo Ceulemans, Stein Aerts · 2017 · Genome Medicine
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Diana Ghinda, Yufei Yang, Shuai Wu, Junfeng Lu, Lan Su, Stefano Damiani, Shankar Tumati, Gerard H. Jansen, Hugues Duffau, Jinsong Wu et al. · 2020 · JCO Precision Oncology
Role of NSC319726 in ovarian cancer based on the bioinformatics analyses
Changhong Wang, Xue Ji, Guang Yang, Hong Ding, Pu Wang · 2015 · OncoTargets and Therapy
Machine Learning for Better Prognostic Stratification and Driver Gene Identification Using Somatic Copy Number Variations in Anaplastic Oligodendroglioma
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PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias
Chiara Ronchini, Alessandro Brozzi, Laura Riva, Lucilla Luzi, Alicja Gruszka, Giorgio E. M. Melloni, Eugenio Scanziani, G. Dharmalingam, Margherita Mutarelli, Vincenzo Belcastro et al. · 2016 · Leukemia
Can aggressive cancers be identified by the “aggressiveness” of their chromatin?
Katerina V. Gurova · 2022 · BioEssays
‘Big data’ approaches for novel anti-cancer drug discovery
Graeme Benstead-Hume, Sarah K. Wooller, Frances M. G. Pearl · 2017 · Expert Opinion on Drug Discovery
A New Insight for the Identification of Oncogenic Variants in Breast and Prostate Cancers in Diverse Human Populations, With a Focus on Latinos
Nelson Varela, Patricia Guevara‐Ramírez, Cristian Acevedo, Tomás Zambrano, Isaac Armendáriz‐Castillo, Santiago Xavier Guerrero, Luis A. Quiñones, Andrés López‐Cortés · 2021 · Frontiers in Pharmacology
High Expression of C1ORF112 Predicts a Poor Outcome: A Potential Target for the Treatment of Low-Grade Gliomas
Zhe Zhang, Zilong Tan, Qiao‐Li Lv, Lichong Wang, Kai Yu, Huan Min Yang, Huaizhen Liang, Tianzhu Lu, Yulong Ji, Junjun Chen et al. · 2021 · Frontiers in Genetics