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Enhanced binding of β-catenin and β-TrCP mediates LMPt’s anti-CSCs activity in colorectal cancer

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Genomic Instability Profiles at the Single Cell Level in Mouse Colorectal Cancers of Defined Genotypes

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Characteristic, Regulation and Targeting Strategies of Cancer Stem Cells and Their Niche in Digestive System Tumors

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Pan-Cancer Genome-Wide DNA Methylation Analyses Revealed That Hypermethylation Influences 3D Architecture and Gene Expression Dysregulation in HOXA Locus During Carcinogenesis of Cancers

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Aldehyde Dehydrogenase 2 Family Member (ALDH2) Is a Therapeutic Index for Oxaliplatin Response on Colorectal Cancer Therapy with Dysfunction p53

Wang, W.-L., Batzorig, U., Hung, C., Wei, P., Huang, C., & Chang, Y. (2022) · BioMed Research International · doi:10.1155/2022/1322788 · Cited by 3

VX-509 attenuates the stemness characteristics of colorectal cancer stem-like cells by regulating the epithelial-mesenchymal transition through Nodal/Smad2/3 signaling

Yuan, Y., Zhang, X.-F., Li, Y., Chen, H.-Q., Wen, T., Zheng, J.-L., Zhao, Z., & Hu, Q. (2024) · World Journal of Stem Cells · doi:10.4252/wjsc.v16.i2.207 · Cited by 2

Safely Targeting Cancer, the Wound That Never Heals, Utilizing CBP/Beta-Catenin Antagonists

Higuchi, Y., Teo, J.-L., Yi, D., & Kahn, M. (2025) · Cancers · doi:10.3390/cancers17091503 · Cited by 3

Pleiotropic effects of all-trans retinoic acid in attenuating the hallmarks of colorectal cancer- challenges and scope of differentiation therapy

Michael, A. A., Balakrishnan, P., Tamizhmani, P., Thirunavukarasu, K., Subramaniam, S., & Velusamy, T. (2025) · Cancer Gene Therapy · doi:10.1038/s41417-025-00996-4 · Cited by 2

Expression and clinical significance of HOXA5, E-cadherin, and β-catenin in cervical squamous cell carcinoma.

Pei, L., Wang, Z.-Q., Shen, J. X., Yang, Y.-Z., Tian, J. H., He, X., Lin, J., Qiao-yan, H., Mo, W., Zhao, H., et al. (2018) · PubMed Central · Cited by 2

Specific Gene Expression in Lgr5+ Stem Cells by Using Cre-Lox Recombination

Dessen, P., Huelsken, J., & Ordóñez‐Morán, P. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0747-3_16 · Cited by 2

Critical regulatory levels in tumor differentiation: Signaling pathways, epigenetics and non‐coding transcripts

Zolghadr, F., Bakhshinejad, B., Davuchbabny, S., Sarrafpour, B., & Seyedasli, N. (2021) · BioEssays · doi:10.1002/bies.202000190 · Cited by 1

A fluorogenic probe for screening aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors

Ghosh, S., Ghosh, S., Majee, A., SenGupta, S., Mukherjee, S., Roy, B., Das, R., & Mukherjee, A. (2025) · Chemical Communications · doi:10.1039/d5cc03947a · Cited by 1

Cancer Stem Cells in Human Gastrointestinal and Hepatic Cancers

Bu, J., Cui, M., Zhang, Y., Yu, L., Zhu, X., Peng, F., & Zhang, H. (2025) · MedComm · doi:10.1002/mco2.70513 · Cited by 1

Multifaceted role of RSPO2: Epigenetics, immunoregulatory, and therapeutic insights in colorectal cancer

Srivastava, A., Tyagi, N., Mubashra, Shukla, A., & Srivastava, S. (2026) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2026.189594 · Cited by 1

Is HOXA5 a Novel Prognostic Biomarker for Uterine Corpus Endometrioid Adenocarcinoma?

Song, C., Kim, K. B., Lee, G. S., Shin, S., & Kim, B. J. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241914758 · Cited by 1

Homeobox A5 and A9 expression and beta-thalassemia

Badr, E., El-Sayed, I.-T., & Alasadi, M. (2021) · British Journal of Biomedical Science · doi:10.1080/09674845.2021.1877926 · Cited by 1

New Advances in Classical Wnt/β-Catenin Signaling in Cancer

Ahmad, A., Ahmad, A., Tao, A., Ahmed, M., Mushtaq, N., Khan, A. A., Li, Q., & Khan, M. W. (2020) · Clinical Oncology and Research · doi:10.31487/j.cor.2020.09.06 · Cited by 1

Identification of Novel Hub Genes Through Expression Profiles Analysis in Adrenocortical CarcinomaPreprint

Yao, C., Zhao, X., Shang, X., Jia, B., Dou, S., Ye, W., & Yang, Y. (2020) · doi:10.21203/rs.3.rs-38768/v1 · Cited by 1

The qRT-PCR assay and the genomic/epigenomic properties of the 10-gene Yin Yang expression ratio signature in non-small cell lung cancer

Narrandes, S. (2019) · Mspace (University of Manitoba)

Hemagglutinating Virus of Japan Envelope (HVJ-E)-Guided Gene Transfer to the Intestinal Epithelium

Imajo, M. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0747-3_19

Cancer Stem Cells in Patient Survival and Therapies in Cancer

Yang, Y., Tian, C., & Meng, W. (2020) · Springer eBooks · doi:10.1007/978-981-15-5120-8_18

In Situ Silver-based Electrochemical Bioreactor In VivoPreprint

Huang, Y. D., Zhong, L., Deng, Z., Wu, P., He, J., Bai, Z., Zhong, Y. P., Peng, H., Zhang, K., Liang, X., et al. (2020) · doi:10.21203/rs.3.rs-103588/v1

A Pilot Study on DNA Methylation in Pediatric HAdV-7-induced SepsisPreprint

Huang, B., Chen, F., Dang, R., Yang, W., Peng, H., Zhang, C., Zuo, Y., Hong, J., Zhao, M., Chen, Y., et al. (2021) · Research Square · doi:10.21203/rs.3.rs-769376/v1

Wnt Signaling-Related Long Noncoding RNAs: Critical Mediators of Drug Resistance in Colon Cancer

Raju, P. V., & Malla, R. R. (2022) · Springer eBooks · doi:10.1007/978-3-030-72702-4_2

In Vitro and in Vivo Assays for Testing Retinoids Effect on Intestinal Progenitors’ Lineage Commitments

Gajera, K. R., Fair, K. L., Moran, G. W., Hannan, N. R. F., Huelsken, J., & Ordóñez‐Morán, P. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3076-1_5

Novel Approach to Measure Transepithelial Electrical Resistance in Intestinal Cells

Marva, G., Ünsal, Ş., Benest, A. V., Bates, D. O., & Ordóñez‐Morán, P. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3076-1_3

WTAP accelerates keloids formation by mediating m6A modification of HOXA5 to suppress p53 pathway

Liu, L., Du, K., & Chen, M. (2023) · Molecular & Cellular Toxicology · doi:10.1007/s13273-023-00383-w

An Overview of Epigenetics Modifications in Normal and Cancer Cell

Mäki‐Nevala, S., & Peltomäki, P. (2023) · Epigenetics and human health · doi:10.1007/978-3-031-42365-9_1

Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro

Kaur, K., & Jewett, A. (2024) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.2024052389

Role of DNA Damage Response in Cancer and Healthy Stem Cells: Genome Stability, Tumor Development and Drug Resistance

Zanoni, M., Simonetti, G., Ulivi, P., & di Rorà, A. G. L. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-15717-2.00109-8

Stemming Colorectal Cancer Growth and Metastasis: HOXA5 Forces Cancer Stem Cells to Differentiate

Tan, S. H., & Barker, N. (2015) · Cancer Cell · doi:10.1016/j.ccell.2015.11.004 · Cited by 29

HOXA5 Promotes Differentiation by Reducing WNT Signaling

(2015) · Cancer Discovery · doi:10.1158/2159-8290.cd-rw2015-240

Imbalance in WNT: retinoic acid signaling dysregulates HOX gene expression: implications for cancer stem cell heterogeneity and CRC patient survival

Osmond, B. T., Zhang, C., Kataboh, P. K., Facey, C. O. B., Opdenaker, L. M., & Boman, B. M. (2026) · Stem Cells Translational Medicine · doi:10.1093/stcltm/szag043

The WNT5A Agonist Foxy5 Reduces the Number of Colonic Cancer Stem Cells in a Xenograft Mouse Model of Human Colonic Cancer

Osman, J., Bellamkonda, K., Liu, Q., Andersson, T., & Sjölander, A. (2019) · Anticancer Research · doi:10.21873/anticanres.13278 · Cited by 28

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

Cheung, P., Xiol, J., Dill, M. T., Yuan, W.-C., Panero, R., Roper, J., Osorio, F. G., Maglic, D., Li, Q., Gurung, B., et al. (2020) · Cell stem cell · doi:10.1016/j.stem.2020.07.003 · Cited by 191