The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Long Noncoding RNAs in Cancer Pathways
Open accessAbstract
Genome-wide cancer mutation analyses are revealing an extensive landscape of functional mutations within the noncoding genome, with profound effects on the expression of long noncoding RNAs (lncRNAs). While the exquisite regulation of lncRNA transcription can provide signals of malignant transformation, we now understand that lncRNAs drive many important cancer phenotypes through their interactions with other cellular macromolecules including DNA, protein, and RNA. Recent advancements in surveying lncRNA molecular mechanisms are now providing the tools to functionally annotate these cancer associated transcripts, making these molecules attractive targets for therapeutic intervention in the fight against cancer.
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Metadata
- Authors
- Schmitt, A. M., & Chang, H. Y.
- Venue
- Cancer Cell
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 29
- Issue
- 4
- Pages
- 452-463
- ISSN
- 1535-6108 (ISSN-L)
- OpenAlex
- W2335029242
- Cited by
- 2,992
- References
- 23
- FWCI
- 114.39
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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