The DOI matches its Crossref record; 78 of the 78 references it cites were found in a registry or an index.
Glycosylation in the Era of Cancer-Targeted Therapy: Where Are We Heading?
Open accessAbstract
This review provides insights on the impact of glycosylation in cancer biology and its influence in the current approaches of targeted cancer therapies in the clinical setting. The roles of glycosylation in cancer signaling, tumor progression, and metastasis are reviewed as well as glycans and glycan-binding proteins in tumor immunomodulation. Moreover, the latest reports on glycans influencing targeted therapeutic approaches in cancer are summarized. Finally, we discuss the future challenges of the field, outlining potential applications of glycan-based biomarkers for patient stratification and strategies for improving personalized cancer treatment.
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Cites
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Self-citationSiglecs and their roles in the immune system
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Cited by
Global view of human protein glycosylation pathways and functions
Schjoldager, K. T., Narimatsu, Y., Joshi, H. J., & Clausen, H. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-00294-x · Cited by 1,309
Tumor microenvironment signaling and therapeutics in cancer progression
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Molecular alterations and targeted therapy in pancreatic ductal adenocarcinoma
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Glycosylation shapes the efficacy and safety of diverse protein, gene and cell therapies
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Glutamine deprivation triggers NAGK-dependent hexosamine salvage
Campbell, S., Mesaros, C., Izzo, L., Affronti, H., Noji, M., Schaffer, B. E., Tsang, T., Sun, K., Trefely, S., Kruijning, S., et al. (2021) · eLife · doi:10.7554/elife.62644 · Cited by 58
Metadata
- Authors
- Mereiter, S., Balmaña, M., Campos, D., Gomes, J., & Reis, C. A.
- Venue
- Cancer Cell
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 36
- Issue
- 1
- Pages
- 6-16
- ISSN
- 1535-6108 (ISSN-L)
- OpenAlex
- W2960011166
- Cited by
- 565
- References
- 78
- FWCI
- 16.47
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Mereiter, S., Balmaña, M., Campos, D., Gomes, J., & Reis, C. A. (2019). Glycosylation in the Era of Cancer-Targeted Therapy: Where Are We Heading? Cancer Cell. https://doi.org/10.1016/j.ccell.2019.06.006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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