The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.
The Compensatory Anti-inflammatory Response Syndrome (CARS) in Critically Ill Patients
Open accessAbstract
Like the systemic inflammatory response syndrome (SIRS), the compensatory anti-inflammatory response syndrome (CARS) is a complex pattern of immunologic responses to severe infection or injury. The difference is that while SIRS is a proinflammatory response tasked with killing infectious organisms through activation of the immune system, CARS is a global deactivation of the immune system tasked with restoring homeostasis. Much research now suggests that the timing and relative magnitude of this response have a profound impact on patient outcomes.
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Sir Isaac Newton, sepsis, SIRS, and CARS
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Sepsis-Induced Apoptosis Causes Progressive Profound Depletion of B and CD4+ T Lymphocytes in Humans
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Cited by
A dynamic COVID-19 immune signature includes associations with poor prognosis
Laing, A. G., Lorenc, A., del Molino del Barrio, I., Das, A., Fish, M., Monin, L., Muñoz-Ruiz, M., McKenzie, D. R., Hayday, T. S., Francos-Quijorna, I., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1038-6 · Cited by 946
Stearns-Kurosawa, D. J., Osuchowski, M. F., Valentine, C., Kurosawa, S., & Remick, D. G. (2011) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathol-011110-130327 · Cited by 549
Mira, J. C., Gentile, L. F., Mathias, B. J., Efron, P. A., Brakenridge, S. C., Mohr, A. M., Moore, F. A., & Moldawer, L. L. (2017) · Critical Care Medicine · doi:10.1097/ccm.0000000000002074 · Cited by 526
The Compensatory Immune-Regulatory Reflex System (CIRS) in Depression and Bipolar Disorder
Maes, M., & Carvalho, A. F. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1016-x · Cited by 306
Postoperative cognitive dysfunction: Involvement of neuroinflammation and neuronal functioning
Hovens, I. B., Schoemaker, R. G., van der Zee, E. A., Absalom, A. R., Heineman, E., & van Leeuwen, B. L. (2014) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2014.02.002 · Cited by 295
Metadata
- Authors
- Ward, N. S., Casserly, B., & Ayala, A.
- Venue
- Clinics in Chest Medicine
- Publisher
- Elsevier BV
- Published
- 2008-12
- Volume
- 29
- Issue
- 4
- Pages
- 617-625
- ISSN
- 0272-5231 (ISSN-L)
- OpenAlex
- W2037418955
- Cited by
- 406
- References
- 65
- FWCI
- 7.45
- Type
- journal article
- Language
- en
- Open access
- green
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- Ward, N. S., Casserly, B., & Ayala, A. (2008). The Compensatory Anti-inflammatory Response Syndrome (CARS) in Critically Ill Patients. Clinics in Chest Medicine. https://doi.org/10.1016/j.ccm.2008.06.010
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
