Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice

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  5. AID-Induced Genotoxic Stress Promotes B Cell Differentiation in the Germinal Center via ATM and LKB1 Signaling
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  9. Molecular pathogenesis of germinal center‐derived B cell lymphomas
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    Zheng, Lang, Li, Yang, Wu, Defa, Xiao, Huan, Zheng, Shilong, Wang, Guan, Sun, Qiu · 2023 · MedComm – Oncology
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    Lourdes Mendez, Jose Maria Polo, Jinmei Yu, Melissa Krupski, B. Belinda Ding, Ari M. Melnick, B. Hilda Ye · 2008 · Molecular and Cellular Biology
  14. The role of BCL6 in lymphomas and routes to therapy
    Simon D. Wagner, Matthew J. Ahearne, Paul Ko Ferrigno · 2010 · British Journal of Haematology
  15. Lymphoma stem cells: enough evidence to support their existence?
    Jose Angel Martinez-Climent, Lorena Fontán, Randy D. Gascoyne, Reiner Siebert, Felipe Prósper · 2010 · Haematologica
  16. The genetic basis of diffuse large B-cell lymphoma
    Laura Pasqualucci · 2013 · Current Opinion in Hematology
  17. Advances in biology, diagnosis and treatment of DLBCL
    Yuanfei Shi, Yi Xin Xu, Huafei Shen, Jie Jin, Hongyan Tong, Wanzhuo Xie · 2024 · Annals of Hematology
  18. High BCL6 expression predicts better prognosis, independent of BCL6 translocation status, translocation partner, or BCL6-deregulating mutations, in gastric lymphoma
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  19. Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma
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  20. Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program
    Michael R. Green, Stefano Monti, Riccardo Dalla‐Favera, Laura Pasqualucci, Nicole C. Walsh, Marc Schmidt‐Supprian, Jeffery Lorne Kutok, Scott J. Rodig, Donna S Neuberg, Klaus Rajewsky et al. · 2011 · Proceedings of the National Academy of Sciences
  21. Requirement for cyclin D3 in germinal center formation and function
    Jonathan U. Peled, J. Jessica Yu, Venkatesh Jeganathan, Enguang Bi, B. Belinda Ding, Melissa Krupski, Rita Shaknovich, Piotr Siciński, Betty Diamond, Matthew D. Scharff et al. · 2010 · Cell Research
  22. Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomas
    Reimann, Maurice, Schrezenmeier, Jens, Richter-Pechanska, Paulina, Dolnik, Anna, Hick, Timon Pablo, Schleich, Kolja, Cai, Xiurong, Fan, Dorothy N. Y., Lohneis, Philipp, Maßwig, Sven et al. · 2021 · Blood
  23. miR-217 is an oncogene that enhances the germinal center reaction
    Virginia G. de Yébenes, Nahikari Bartolomé‐Izquierdo, Rubén Nogales‐Cadenas, Pablo Pérez‐Durán, Sonia M. Mur, Nerea Martı́nez, Lorena Di Lisio, Davide F. Robbiani, Alberto Pascual-Montano, Marta Cañamero et al. · 2014 · Blood
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    Akram Méndez, Luis Mendoza · 2016 · PLoS Computational Biology
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    Bojan Bujisic, Aude De Gassart, Rémy Tallant, Olivier Demaria, Léa Zaffalon, Sonia Tassadit Chelbi, Michel F. Gilliet, Francesco Bertoni, Fabio Martinon · 2017 · Blood
  26. Pathogenetic and Clinical Implications of Non-Immunoglobulin; BCL6 Translocations in B-Cell Non-Hodgkin's Lymphoma
    Hitoshi Ohno · 2006 · Journal of the Japan Society of the Reticuloendothelial System
  27. IL4 and IL21 cooperate to induce the high Bcl6 protein level required for germinal center formation
    Stéphane Chevrier, Tobias Kratina, Dianne Emslie, David Mathew Tarlinton, Lynn M. Corcoran · 2017 · Immunology and Cell Biology
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    Abdallah Souabni, Wolfram Jochum, Meinrad Busslinger · 2006 · Blood
  29. Mechanisms of action of BCL6 during germinal center B cell development
    Chuanxin Huang, Ari M. Melnick · 2015 · Science China Life Sciences
  30. miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma
    Nahikari Bartolomé‐Izquierdo, Virginia G. de Yébenes, Ángel F. Álvarez-Prado, Sonia M. Mur, Juan Antonio López, Sergio Roa, Jesús Vázquez, Almudena R. Ramiro · 2017 · Blood
  31. Somatic stem cells and the origin of cancer
    Jose Angel Martinez-Climent, Enrique José Andreu, Felipe Prósper · 2006 · Clinical & Translational Oncology
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    Marcus J Robinson, Zhoujie Ding, Catherine Pitt, Erica J. Brodie, Isaak Quast, David Mathew Tarlinton, Dimitra Zotos · 2020 · Cell Reports
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    Sajjad Hussain, Tibor Bedekovics, Qiuying Liu, Wenqian Hu, Haeseung Jeon, Sarah H. Johnson, George Vasmatzis, Danielle G. May, Kyle J. Roux, Paul J. Galardy · 2018 · Blood
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  38. HVEM network signaling in cancer
    John R. Šedý, Parham Ramezani-Rad · 2019 · Advances in cancer research
  39. B cell lymphoma and myeloma in murine Gaucher's disease
    Elena Pavlova, SZ Wang, Joy Archer, Nick Dekker, Johannes M. F. G. Aerts, Stefan Karlsson, TM Cox · 2013 · The Journal of Pathology
  40. UCH-L1 is induced in germinal center B cells and identifies patients with aggressive germinal center diffuse large B-cell lymphoma
    Tibor Bedekovics, Sajjad Hussain, Andrew L. Feldman, Paul J. Galardy · 2015 · Blood
  41. Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer Interface
    Mingxing Teng, Scott B. Ficarro, Hojong Yoon, Jianwei Che, Jing Zhou, Eric S. Fischer, Jarrod A. Marto, Tinghu Zhang, Nathanael S. Gray · 2020 · ACS Medicinal Chemistry Letters
  42. Frequent mutations in the amino-terminal domain of BCL7A impair its tumor suppressor role in DLBCL
    Carlos Baliñas-Gavira, María Isabel Rodríguez, Álvaro Andrades, Marta Cuadros, Juan Carlos Álvarez-Pérez, Ángel F. Álvarez-Prado, Virginia G. de Yébenes, Sabina Sánchez-Hernández, Elvira Fernández-Vigo, Javier Muñoz et al. · 2020 · Leukemia
  43. BCL6 confers KRAS-mutant non–small-cell lung cancer resistance to BET inhibitors
    Jiawei Guo, Yanan Liu, Jing Lv, Bin Zou, Zhi Chen, Kun Li, Juanjuan Feng, Zhenyu Cai, Lai Wei, Mingyao Liu et al. · 2021 · Journal of Clinical Investigation
  44. Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas
    Samir Sunil Parekh, Gilbert G. Privé, Ari M. Melnick · 2008 · Leukemia & lymphoma/Leukemia and lymphoma
  45. BCL6-mediated Attenuation of DNA Damage Sensing Triggers Growth Arrest and Senescence through a p53-dependent Pathway in a Cell Context-dependent Manner
    Stella Maris Ranuncolo, Wang Ling, Jose Maria Polo, Tania Dell’Oso, Jamil K. Dierov, Terry J. Gaymes, Feyruz Virgilia Rassool, Martin P Carroll, Ari M. Melnick · 2008 · Journal of Biological Chemistry
  46. t(14;18)-negative follicular lymphomas are associated with a high frequency of BCL6 rearrangement at the alternative breakpoint region
    Keni Gu, Kai Fu, Smrati Jain, Zhongfen Liu, Javeed Iqbal, Min Li, Warren G. Sanger, Dennis D. Weisenburger, Timothy C. Greiner, Patricia A. Aoun et al. · 2009 · Modern Pathology
  47. RHO Family GTPases in the Biology of Lymphoma
    Claudia Voena, Roberto Chiarle · 2019 · Cells
  48. Characterization of Bcor expression in mouse development
    Joseph A. Wamstad, Vivian J. Bardwell · 2007 · Gene Expression Patterns
  49. Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cells
    Jose Maria Polo, Weimin Ci, Jonathan D. Licht, Ari M. Melnick · 2008 · Blood
  50. Deregulated expression of HDAC9 in B-cells promotes development of lymphoproliferative disease and lymphoma
    Veronica Gil, Govind Bhagat, L. Howell, Jing Zhang, Chong Kim, Sven Stengel, Francisco Vega, Arthur Zelent, Kevin R. Petrie · 2016 · Disease Models & Mechanisms
  51. Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation
    Martín A. Rivas, Cem Meydan, Christopher R. Chin, Matt F. Challman, Daleum Kim, Bhavneet Bhinder, Andreas Kloetgen, Aaron D. Viny, Matt R. Teater, Dylan R. McNally et al. · 2021 · Nature Immunology
  52. Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expression
    Takami Sato, T. H. Tran, Amy R. Peck, Melanie A. Girondo, C Liu, Chelain R. Goodman, Lynn M. Neilson, Boris Freydin, Inna Chervoneva, Terry Hyslop et al. · 2013 · Oncogene
  53. The LRF transcription factor regulates mature B cell development and the germinal center response in mice
    Nagisa Sakurai, Manami Maeda, Sung-Uk Lee, Yuichi Ishikawa, Min Li, John C. Williams, Lisheng Wang, Leila Su, Mai Suzuki, Toshiki I. Saito et al. · 2011 · Journal of Clinical Investigation
  54. Epigenetic Function of Activation-Induced Cytidine Deaminase and Its Link to Lymphomagenesis
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  55. Association of Ig/BCL6 translocations with germinal center B lymphocytes in human lymphoid tissues: implications for malignant transformation
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  56. Differentiation of Rodent Immune and Hematopoietic System Reactive Lesions from Neoplasias
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  57. STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL)
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  58. PDCD2, a protein whose expression is repressed by BCL6, induces apoptosis in human cells by activation of the caspase cascade
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  59. CD40 Pathway Activation Status Predicts Response to CD40 Therapy in Diffuse Large B Cell Lymphoma
    Bart E. Burington, Yue Peng, Xiaoyan Shi, Ranjana H. Advani, Jeffrey Lau, Jenille Tan, Susanna Y. Stinson, Jeremy Stinson, Thomas Januario, Sven de Vos et al. · 2011 · Science Translational Medicine
  60. Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis
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  61. BACH2–BCL6 balance regulates selection at the pre-B cell receptor checkpoint
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  62. Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis
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  66. Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphoma
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  67. Germinal centers
    Mark Jay Shlomchik, Florian J. Weisel · 2012 · Immunological Reviews
  68. H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patients
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  69. Repression of the PDCD2 gene by BCL6 and the implications for the pathogenesis of human B and T cell lymphomas
    Beverly W. Baron, Nancy J. Zeleznik‐Le, Miriam J. Baron, Catherine M. Theisler, Dezheng Huo, Matthew D. Krasowski, Michael J. Thirman, Rebecca Marlene Baron, Joseph M. Baron · 2007 · Proceedings of the National Academy of Sciences
  70. The Drosophila BCL6 homolog ken and barbie promotes somatic stem cell self-renewal in the testis niche
    Melanie Issigonis, Erika L. Matunis · 2012 · Developmental Biology
  71. Suppression of BCL6 function by HDAC inhibitor mediated acetylation and chromatin modification enhances BET inhibitor effects in B-cell lymphoma cells
    María G. Cortiguera, Lorena García-Gaipo, Simon D. Wagner, Javier León, Ana Batlle‐López, M. Dolores Delgado · 2019 · Scientific Reports
  72. LMO 2 and BCL 6 are associated with improved survival in primary central nervous system lymphoma
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  73. Detection of somatic quantitative genetic alterations by multiplex polymerase chain reaction for the prediction of outcome in diffuse large B-cell lymphomas
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  74. BLMP-1/Blimp-1 Regulates the Spatiotemporal Cell Migration Pattern in C. elegans
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  75. Resveratrol induces apoptosis in transformed follicular lymphoma OCI-LY8 cells: Evidence for a novel mechanism involving inhibition of BCL6 signaling
    Anthony C. Faber, Thomas C. Chiles · 2006 · International Journal of Oncology
  76. NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biological Considerations of Hematological Relapse following Allogeneic Stem Cell Transplantation Unrelated to Graft-versus-Tumor Effects: State of the Science
    Mitchell Stuart Cairo, Craig T. Jordan, Carlo C. Maley, C. Chao, Ari M. Melnick, Scott A. Armstrong, Warren D. Shlomchik, Jeff Molldrem, Soldano Ferrone, Crystal Lee Mackall et al. · 2010 · Transplantation and Cellular Therapy
  77. c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphoma
    Henrik Vibe Scheller, Stephanie Tobollik, André Kutzera, Maxwell D. Eder, J Unterlehberg, Ines Pfeil, Berit Jungnickel · 2009 · Oncogene
  78. Anomalous constitutive Src kinase activity promotes B lymphoma survival and growth
    Jiyuan Ke, R. Lakshman Chelvarajan, Vishal J. Sindhava, Darrell A. Robertson, Lazaros J. Lekakis, C. DARRELL JENNINGS, Subbarao Bondada · 2009 · Molecular Cancer
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  80. AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma
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  81. Sequential Transcription Factor Targeting for Diffuse Large B-Cell Lymphomas
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  82. The BCL6‐associated transcriptional co‐repressor, MTA3, is selectively expressed by germinal centre B cells and lymphomas of putative germinal centre derivation
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  83. Discovery of novel BCL6-Targeting PROTACs with effective antitumor activities against DLBCL in vitro and in vivo
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  84. B-cell Lymphoma 6 Inhibitors: Current Advances and Prospects of Drug Development for Diffuse Large B-cell Lymphomas
    Haijun Gu, Jia He, Yuzhan Li, Dazhao Mi, Tian Guan, Weikai Guo, Bo Liu, Yihua Chen · 2022 · Journal of Medicinal Chemistry
  85. Concurrent inhibition of MYC and BCL2 is a potentially effective treatment strategy for double hit and triple hit B-cell lymphomas
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  86. An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivo
    Yajing Xing, Weikai Guo, Min Yi Wu, Jiuqing Xie, Dongxia Huang, Pan Hu, Miaoran Zhou, Lin Zhang, Qiansen Zhang, Peili Wang et al. · 2022 · Cancer Letters
  87. Pathogenesis of diffuse large B cell lymphoma
    Wing Chung Chan · 2010 · International Journal of Hematology
  88. The Novel IKK2 Inhibitor LY2409881 Potently Synergizes with Histone Deacetylase Inhibitors in Preclinical Models of Lymphoma through the Downregulation of NF-κB
    Changchun Deng, Mark R. Lipstein, Richard Rodriguez, Xavier O. Jirau Serrano, Christine M. Mcintosh, Wei‐Yann Tsai, Andrew S. Wasmuth, Susan Jaken, Owen A. O’Connor · 2014 · Clinical Cancer Research
  89. Specific peptides for the therapeutic targeting of oncogenes
    Gilbert G. Privé, Ari M. Melnick · 2005 · Current Opinion in Genetics & Development
  90. A Synchronous IRF4-Dependent Gene Regulatory Network in B and Helper T Cells Orchestrating the Antibody Response
    Sarah L. Cook, Marissa C. Franke, Evelyn P. Sievert, Roger Sciammas · 2020 · Trends in Immunology
  91. TBL1X: At the crossroads of transcriptional and posttranscriptional regulation
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  92. PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas
    Beverly W. Baron, John Anastasi, Elizabeth M. Hyjek, Juraj Bies, Poluru L. Reddy, Jingfang Dong, Loren J. Joseph, Michael J. Thirman, Kristen Wroblewski, Linda Wolff et al. · 2012 · Proceedings of the National Academy of Sciences
  93. SEMMs: Somatically Engineered Mouse Models. A New Tool for In Vivo Disease Modeling for Basic and Translational Research
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  94. Targeting Epigenetic protein–protein Interactions With small-molecule Inhibitors
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  96. Molecular classification and therapeutics in diffuse large B-cell lymphoma
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  98. Dysregulation of miRNAs in DLBCL: Causative Factor for Pathogenesis, Diagnosis and Prognosis
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  99. Gene Interaction Network Regulates Plasma Cell Differentiation
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  100. Rewired NFκB signaling as a potentially actionable feature of activated B‐cell‐like diffuse large B‐cell lymphoma
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