Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice
Cattoretti, Giorgio, Pasqualucci, Laura, Ballon, Gianna, Tam, Wayne, Nandula, Subhadra V., Shen, Qiong, Mo, Tongwei, Murty, Vundavalli V., Dalla-Favera, Riccardo·2005·Cancer Cell
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Items 101–200 of 387
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- Development of covalent inhibitors: Principle, design, and application in cancerZheng, Lang, Li, Yang, Wu, Defa, Xiao, Huan, Zheng, Shilong, Wang, Guan, Sun, Qiu · 2023 · MedComm – Oncology
- CtBP Is an Essential Corepressor for BCL6 AutoregulationLourdes Mendez, Jose Maria Polo, Jinmei Yu, Melissa Krupski, B. Belinda Ding, Ari M. Melnick, B. Hilda Ye · 2008 · Molecular and Cellular Biology
- The role of BCL6 in lymphomas and routes to therapySimon D. Wagner, Matthew J. Ahearne, Paul Ko Ferrigno · 2010 · British Journal of Haematology
- Lymphoma stem cells: enough evidence to support their existence?Jose Angel Martinez-Climent, Lorena Fontán, Randy D. Gascoyne, Reiner Siebert, Felipe Prósper · 2010 · Haematologica
- The genetic basis of diffuse large B-cell lymphomaLaura Pasqualucci · 2013 · Current Opinion in Hematology
- Advances in biology, diagnosis and treatment of DLBCLYuanfei Shi, Yi Xin Xu, Huafei Shen, Jie Jin, Hongyan Tong, Wanzhuo Xie · 2024 · Annals of Hematology
- High BCL6 expression predicts better prognosis, independent of BCL6 translocation status, translocation partner, or BCL6-deregulating mutations, in gastric lymphomaYun-Wen Chen, Xiao-Tong Hu, Anthony C. T. Liang, Wing-Yan Au, C.C So, Michelle L. Y. Wong, Lijun Shen, Qian Tao, Kent‐Man Chu, Yok‐Lam Kwong et al. · 2006 · Blood
- Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphomaBenedetta Apollonio, Filomena Spada, Nedyalko Petrov, Domenico Cozzetto, Despoina Papazoglou, Peter Jarvis, Shichina Kannambath, Manuela Terranova-Barberio, Rose‐Marie Amini, Gunilla Enblad et al. · 2023 · Journal of Clinical Investigation
- Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific programMichael R. Green, Stefano Monti, Riccardo Dalla‐Favera, Laura Pasqualucci, Nicole C. Walsh, Marc Schmidt‐Supprian, Jeffery Lorne Kutok, Scott J. Rodig, Donna S Neuberg, Klaus Rajewsky et al. · 2011 · Proceedings of the National Academy of Sciences
- Requirement for cyclin D3 in germinal center formation and functionJonathan U. Peled, J. Jessica Yu, Venkatesh Jeganathan, Enguang Bi, B. Belinda Ding, Melissa Krupski, Rita Shaknovich, Piotr Siciński, Betty Diamond, Matthew D. Scharff et al. · 2010 · Cell Research
- Adaptive T-cell immunity controls senescence-prone MyD88- or CARD11-mutant B-cell lymphomasReimann, Maurice, Schrezenmeier, Jens, Richter-Pechanska, Paulina, Dolnik, Anna, Hick, Timon Pablo, Schleich, Kolja, Cai, Xiurong, Fan, Dorothy N. Y., Lohneis, Philipp, Maßwig, Sven et al. · 2021 · Blood
- miR-217 is an oncogene that enhances the germinal center reactionVirginia G. de Yébenes, Nahikari Bartolomé‐Izquierdo, Rubén Nogales‐Cadenas, Pablo Pérez‐Durán, Sonia M. Mur, Nerea Martı́nez, Lorena Di Lisio, Davide F. Robbiani, Alberto Pascual-Montano, Marta Cañamero et al. · 2014 · Blood
- A Network Model to Describe the Terminal Differentiation of B CellsAkram Méndez, Luis Mendoza · 2016 · PLoS Computational Biology
- Impairment of both IRE1 expression and XBP1 activation is a hallmark of GCB DLBCL and contributes to tumor growthBojan Bujisic, Aude De Gassart, Rémy Tallant, Olivier Demaria, Léa Zaffalon, Sonia Tassadit Chelbi, Michel F. Gilliet, Francesco Bertoni, Fabio Martinon · 2017 · Blood
- Pathogenetic and Clinical Implications of Non-Immunoglobulin; BCL6 Translocations in B-Cell Non-Hodgkin's LymphomaHitoshi Ohno · 2006 · Journal of the Japan Society of the Reticuloendothelial System
- IL4 and IL21 cooperate to induce the high Bcl6 protein level required for germinal center formationStéphane Chevrier, Tobias Kratina, Dianne Emslie, David Mathew Tarlinton, Lynn M. Corcoran · 2017 · Immunology and Cell Biology
- Oncogenic role of Pax5 in the T-lymphoid lineage upon ectopic expression from the immunoglobulin heavy-chain locusAbdallah Souabni, Wolfram Jochum, Meinrad Busslinger · 2006 · Blood
- Mechanisms of action of BCL6 during germinal center B cell developmentChuanxin Huang, Ari M. Melnick · 2015 · Science China Life Sciences
- miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphomaNahikari Bartolomé‐Izquierdo, Virginia G. de Yébenes, Ángel F. Álvarez-Prado, Sonia M. Mur, Juan Antonio López, Sergio Roa, Jesús Vázquez, Almudena R. Ramiro · 2017 · Blood
- Somatic stem cells and the origin of cancerJose Angel Martinez-Climent, Enrique José Andreu, Felipe Prósper · 2006 · Clinical & Translational Oncology
- FBXO11 inactivation leads to abnormal germinal-center formation and lymphoproliferative diseaseChristof Schneider, Ning Kon, Letizia Amadori, Qiong “John” Shen, Friederike H. Schwartz, Benjamin Tischler, Marion Bossennec, David Dominguez-Sola, Govind Bhagat, Wei Jun Gu et al. · 2016 · Blood
- The Amount of BCL6 in B Cells Shortly after Antigen Engagement Determines Their Representation in Subsequent Germinal CentersMarcus J Robinson, Zhoujie Ding, Catherine Pitt, Erica J. Brodie, Isaak Quast, David Mathew Tarlinton, Dimitra Zotos · 2020 · Cell Reports
- TCL1A expression delineates biological and clinical variability in B-cell lymphomaMohit Aggarwal, Raquel Villuendas, Gonzalo Goméz-López, Socorro Marıá Rodríguez-Pinilla, Margarita Sánchez‐Beato, David Alvarez, Nerea Martı́nez, Antonia Rodríguez, Maria Esther Castillo, Francisca Inmaculada Camacho et al. · 2008 · Modern Pathology
- BCL6 is regulated by p53 through a response element frequently disrupted in B-cell non-Hodgkin lymphomaOfer Margalit, Hila Wiener Amram, Ninette Amariglio, Amos J. Simon, Sigal Shaklai, Galit Granot, Neri Minsky, Avichai Shimoni, Alon Harmelin, David Givol et al. · 2005 · Blood
- UCH-L1 bypasses mTOR to promote protein biosynthesis and is required for MYC-driven lymphomagenesis in miceSajjad Hussain, Tibor Bedekovics, Qiuying Liu, Wenqian Hu, Haeseung Jeon, Sarah H. Johnson, George Vasmatzis, Danielle G. May, Kyle J. Roux, Paul J. Galardy · 2018 · Blood
- Frequency ofBCL2andBCL6translocations in follicular lymphoma: Relation with histological and clinical featuresAndrea Díaz-Alderete, Angela Alvárez Doval, Francisca Inmaculada Camacho, L. Sanchez Verde, Pilar Sabin, Reyes Arranz-Sáez, Carmen Bellas, Carlos Corbacho, Juana Gil, María Perez-Martín et al. · 2008 · Leukemia & lymphoma/Leukemia and lymphoma
- HVEM network signaling in cancerJohn R. Šedý, Parham Ramezani-Rad · 2019 · Advances in cancer research
- B cell lymphoma and myeloma in murine Gaucher's diseaseElena Pavlova, SZ Wang, Joy Archer, Nick Dekker, Johannes M. F. G. Aerts, Stefan Karlsson, TM Cox · 2013 · The Journal of Pathology
- UCH-L1 is induced in germinal center B cells and identifies patients with aggressive germinal center diffuse large B-cell lymphomaTibor Bedekovics, Sajjad Hussain, Andrew L. Feldman, Paul J. Galardy · 2015 · Blood
- Rationally Designed Covalent BCL6 Inhibitor That Targets a Tyrosine Residue in the Homodimer InterfaceMingxing Teng, Scott B. Ficarro, Hojong Yoon, Jianwei Che, Jing Zhou, Eric S. Fischer, Jarrod A. Marto, Tinghu Zhang, Nathanael S. Gray · 2020 · ACS Medicinal Chemistry Letters
- Frequent mutations in the amino-terminal domain of BCL7A impair its tumor suppressor role in DLBCLCarlos Baliñas-Gavira, María Isabel Rodríguez, Álvaro Andrades, Marta Cuadros, Juan Carlos Álvarez-Pérez, Ángel F. Álvarez-Prado, Virginia G. de Yébenes, Sabina Sánchez-Hernández, Elvira Fernández-Vigo, Javier Muñoz et al. · 2020 · Leukemia
- BCL6 confers KRAS-mutant non–small-cell lung cancer resistance to BET inhibitorsJiawei Guo, Yanan Liu, Jing Lv, Bin Zou, Zhi Chen, Kun Li, Juanjuan Feng, Zhenyu Cai, Lai Wei, Mingyao Liu et al. · 2021 · Journal of Clinical Investigation
- Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomasSamir Sunil Parekh, Gilbert G. Privé, Ari M. Melnick · 2008 · Leukemia & lymphoma/Leukemia and lymphoma
- BCL6-mediated Attenuation of DNA Damage Sensing Triggers Growth Arrest and Senescence through a p53-dependent Pathway in a Cell Context-dependent MannerStella Maris Ranuncolo, Wang Ling, Jose Maria Polo, Tania Dell’Oso, Jamil K. Dierov, Terry J. Gaymes, Feyruz Virgilia Rassool, Martin P Carroll, Ari M. Melnick · 2008 · Journal of Biological Chemistry
- t(14;18)-negative follicular lymphomas are associated with a high frequency of BCL6 rearrangement at the alternative breakpoint regionKeni Gu, Kai Fu, Smrati Jain, Zhongfen Liu, Javeed Iqbal, Min Li, Warren G. Sanger, Dennis D. Weisenburger, Timothy C. Greiner, Patricia A. Aoun et al. · 2009 · Modern Pathology
- RHO Family GTPases in the Biology of LymphomaClaudia Voena, Roberto Chiarle · 2019 · Cells
- Characterization of Bcor expression in mouse developmentJoseph A. Wamstad, Vivian J. Bardwell · 2007 · Gene Expression Patterns
- Reversible disruption of BCL6 repression complexes by CD40 signaling in normal and malignant B cellsJose Maria Polo, Weimin Ci, Jonathan D. Licht, Ari M. Melnick · 2008 · Blood
- Deregulated expression of HDAC9 in B-cells promotes development of lymphoproliferative disease and lymphomaVeronica Gil, Govind Bhagat, L. Howell, Jing Zhang, Chong Kim, Sven Stengel, Francisco Vega, Arthur Zelent, Kevin R. Petrie · 2016 · Disease Models & Mechanisms
- Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformationMartín A. Rivas, Cem Meydan, Christopher R. Chin, Matt F. Challman, Daleum Kim, Bhavneet Bhinder, Andreas Kloetgen, Aaron D. Viny, Matt R. Teater, Dylan R. McNally et al. · 2021 · Nature Immunology
- Prolactin suppresses a progestin-induced CK5-positive cell population in luminal breast cancer through inhibition of progestin-driven BCL6 expressionTakami Sato, T. H. Tran, Amy R. Peck, Melanie A. Girondo, C Liu, Chelain R. Goodman, Lynn M. Neilson, Boris Freydin, Inna Chervoneva, Terry Hyslop et al. · 2013 · Oncogene
- The LRF transcription factor regulates mature B cell development and the germinal center response in miceNagisa Sakurai, Manami Maeda, Sung-Uk Lee, Yuichi Ishikawa, Min Li, John C. Williams, Lisheng Wang, Leila Su, Mai Suzuki, Toshiki I. Saito et al. · 2011 · Journal of Clinical Investigation
- Epigenetic Function of Activation-Induced Cytidine Deaminase and Its Link to LymphomagenesisPilar M. Domínguez, Rita Shaknovich · 2014 · Frontiers in Immunology
- Association of Ig/BCL6 translocations with germinal center B lymphocytes in human lymphoid tissues: implications for malignant transformationXuwei Yang, Koutetsu Lee, JONATHAN W. SAID, Xun Gong, Ke Zhang · 2006 · Blood
- Differentiation of Rodent Immune and Hematopoietic System Reactive Lesions from NeoplasiasJerrold Michael Ward, Jerold E. Rehg, Herbert C. Morse · 2012 · Toxicologic Pathology
- STAT6-mediated BCL6 repression in primary mediastinal B-cell lymphoma (PMBL)Olga Ritz, Karolin Rommel, Karola Dorsch, Elena Kelsch, Julia Melzner, Michaela Buck, Karen Leroy, Vasiliki Papadopoulou, Simon D. Wagner, Ralf B. Marienfeld et al. · 2013 · Oncotarget
- PDCD2, a protein whose expression is repressed by BCL6, induces apoptosis in human cells by activation of the caspase cascadeBeverly W. Baron, Elizabeth M. Hyjek, Betty Gladstone, Michael J. Thirman, Joseph M. Baron · 2010 · Blood Cells Molecules and Diseases
- CD40 Pathway Activation Status Predicts Response to CD40 Therapy in Diffuse Large B Cell LymphomaBart E. Burington, Yue Peng, Xiaoyan Shi, Ranjana H. Advani, Jeffrey Lau, Jenille Tan, Susanna Y. Stinson, Jeremy Stinson, Thomas Januario, Sven de Vos et al. · 2011 · Science Translational Medicine
- Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesisRené Rauschmeier, Annika Reinhardt, Charlotte Gustafsson, Vassilis Glaros, Artem V. Artemov, Josefine Dunst, Reshma Taneja, Igor I. Adameyko, Robert Månsson, Meinrad Busslinger et al. · 2021 · The Journal of Experimental Medicine
- BACH2–BCL6 balance regulates selection at the pre-B cell receptor checkpointSrividya Swaminathan, Cihangir Duy, Markus Müschen · 2013 · Trends in Immunology
- Inducible knock-out of BCL6 in lymphoma cells results in tumor stasisSchlager, Stefanie, Salomon, Carina, Olt, Sabine, Albrecht, Christoph, Ebert, Anja, Bergner, Oliver, Wachter, Johannes, Trapani, Francesca, Gerlach, Daniel, Voss, Tilman et al. · 2020 · Oncotarget
- Distinct Apoptotic Signaling Characteristics of the Anti-CD40 Monoclonal Antibody Dacetuzumab and Rituximab Produce Enhanced Antitumor Activity in Non-Hodgkin LymphomaTimothy S. Lewis, Renée S. McCormick, Kim K. Emmerton, Jeffrey Lau, Shang‐Fan Yu, Julie A. McEarchern, Iqbal S. Grewal, Che‐Leung Law · 2011 · Clinical Cancer Research
- BCL6 Represses Smad Signaling in Transforming Growth Factor-β ResistanceDegang Wang, Jianyin Long, Fangyan Dai, Min Liang, Xin‐Hua Feng, Xia Lin · 2008 · Cancer Research
- The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell LymphomaDavid M. Wong, Lingli Li, Sabine Jurado, Ashleigh King, Rebecca Bamford, Meaghan Wall, Mannu Walia, Gemma L. Kelly, Carl R. Walkley, David Mathew Tarlinton et al. · 2016 · Cell Reports
- Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphomaElena Battistello, Natalya Katanayeva, Elie Dheilly, Daniele Tavernari, Maria Donaldson Collier, Luca Bonsignore, Margot Thome, Amanda L. Christie, Mark Alan Murakami, Olivier Alain Michielin et al. · 2018 · Blood
- Germinal centersMark Jay Shlomchik, Florian J. Weisel · 2012 · Immunological Reviews
- H3K9me3-mediated epigenetic regulation of senescence in mice predicts outcome of lymphoma patientsKolja Schleich, Julia Kase, Jan R. Dörr, Saskia Trescher, Animesh Bhattacharya, Yong Yu, Elizabeth M. Wailes, Dorothy Ngo-Yin Fan, Philipp Lohneis, Maja Milanovic et al. · 2020 · Nature Communications
- Repression of the PDCD2 gene by BCL6 and the implications for the pathogenesis of human B and T cell lymphomasBeverly W. Baron, Nancy J. Zeleznik‐Le, Miriam J. Baron, Catherine M. Theisler, Dezheng Huo, Matthew D. Krasowski, Michael J. Thirman, Rebecca Marlene Baron, Joseph M. Baron · 2007 · Proceedings of the National Academy of Sciences
- The Drosophila BCL6 homolog ken and barbie promotes somatic stem cell self-renewal in the testis nicheMelanie Issigonis, Erika L. Matunis · 2012 · Developmental Biology
- Suppression of BCL6 function by HDAC inhibitor mediated acetylation and chromatin modification enhances BET inhibitor effects in B-cell lymphoma cellsMaría G. Cortiguera, Lorena García-Gaipo, Simon D. Wagner, Javier León, Ana Batlle‐López, M. Dolores Delgado · 2019 · Scientific Reports
- LMO 2 and BCL 6 are associated with improved survival in primary central nervous system lymphomaChen Lossos, Soley Bayraktar, Elizabeth P. Weinzierl, Sheren Fouad Younes, Peter J. Hosein, Robert John Tibshirani, Jocelyn S Posthumus, Lisa Marie DeAngelis, Jeffrey J. Raizer, David Schiff et al. · 2014 · British Journal of Haematology
- Detection of somatic quantitative genetic alterations by multiplex polymerase chain reaction for the prediction of outcome in diffuse large B-cell lymphomasFabrice Jardin, Philippe Ruminy, Jean Pierre Kerckaert, Françoise Parmentier, Jean‐Michel Picquenot, Sabine Quief, Céline Villenet, Gérard Buchonnet, Mario Tosi, Thierry Frébourg et al. · 2008 · Haematologica
- BLMP-1/Blimp-1 Regulates the Spatiotemporal Cell Migration Pattern in C. elegansTsai-Fang Huang, Chun-Yi Cho, Yi-Ting Cheng, Jheng-Wei Huang, Yunzhe Wu, Athena Yi-Chun Yeh, Kiyoji Nishiwaki, Shih‐Chung Chang, Yi‐Chun Wu · 2014 · PLoS Genetics
- Resveratrol induces apoptosis in transformed follicular lymphoma OCI-LY8 cells: Evidence for a novel mechanism involving inhibition of BCL6 signalingAnthony C. Faber, Thomas C. Chiles · 2006 · International Journal of Oncology
- NCI First International Workshop on the Biology, Prevention, and Treatment of Relapse After Allogeneic Hematopoietic Stem Cell Transplantation: Report from the Committee on the Biological Considerations of Hematological Relapse following Allogeneic Stem Cell Transplantation Unrelated to Graft-versus-Tumor Effects: State of the ScienceMitchell Stuart Cairo, Craig T. Jordan, Carlo C. Maley, C. Chao, Ari M. Melnick, Scott A. Armstrong, Warren D. Shlomchik, Jeff Molldrem, Soldano Ferrone, Crystal Lee Mackall et al. · 2010 · Transplantation and Cellular Therapy
- c-Myc overexpression promotes a germinal center-like program in Burkitt's lymphomaHenrik Vibe Scheller, Stephanie Tobollik, André Kutzera, Maxwell D. Eder, J Unterlehberg, Ines Pfeil, Berit Jungnickel · 2009 · Oncogene
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- AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphomaXiwen Gu, Carmen Jane Booth, Zongzhi Z. Liu, Matthew P. Strout · 2015 · Blood
- Sequential Transcription Factor Targeting for Diffuse Large B-Cell LymphomasLeandro C. A. Cerchietti, Jose Maria Polo, Gustavo Felippe da Silva, Pedro Farinha, Rita Shaknovich, Randy D. Gascoyne, Steven F. Dowdy, Ari M. Melnick · 2008 · Cancer Research
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- B-cell Lymphoma 6 Inhibitors: Current Advances and Prospects of Drug Development for Diffuse Large B-cell LymphomasHaijun Gu, Jia He, Yuzhan Li, Dazhao Mi, Tian Guan, Weikai Guo, Bo Liu, Yihua Chen · 2022 · Journal of Medicinal Chemistry
- Concurrent inhibition of MYC and BCL2 is a potentially effective treatment strategy for double hit and triple hit B-cell lymphomasMunevver Cinar, FRED P. ROSENFELT, Sepehr Rokhsar, Jean Raphael Lopategui, Raju K. Pillai, Melissa Cervania, Andy Pao, Bekir Cinar, Serhan Alkan · 2015 · Leukemia Research
- An orally available small molecule BCL6 inhibitor effectively suppresses diffuse large B cell lymphoma cells growth in vitro and in vivoYajing Xing, Weikai Guo, Min Yi Wu, Jiuqing Xie, Dongxia Huang, Pan Hu, Miaoran Zhou, Lin Zhang, Qiansen Zhang, Peili Wang et al. · 2022 · Cancer Letters
- Pathogenesis of diffuse large B cell lymphomaWing Chung Chan · 2010 · International Journal of Hematology
- The Novel IKK2 Inhibitor LY2409881 Potently Synergizes with Histone Deacetylase Inhibitors in Preclinical Models of Lymphoma through the Downregulation of NF-κBChangchun Deng, Mark R. Lipstein, Richard Rodriguez, Xavier O. Jirau Serrano, Christine M. Mcintosh, Wei‐Yann Tsai, Andrew S. Wasmuth, Susan Jaken, Owen A. O’Connor · 2014 · Clinical Cancer Research
- Specific peptides for the therapeutic targeting of oncogenesGilbert G. Privé, Ari M. Melnick · 2005 · Current Opinion in Genetics & Development
- A Synchronous IRF4-Dependent Gene Regulatory Network in B and Helper T Cells Orchestrating the Antibody ResponseSarah L. Cook, Marissa C. Franke, Evelyn P. Sievert, Roger Sciammas · 2020 · Trends in Immunology
- TBL1X: At the crossroads of transcriptional and posttranscriptional regulationBetsy A. Pray, Youssef Youssef, Lapo Alinari · 2022 · Experimental Hematology
- PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomasBeverly W. Baron, John Anastasi, Elizabeth M. Hyjek, Juraj Bies, Poluru L. Reddy, Jingfang Dong, Loren J. Joseph, Michael J. Thirman, Kristen Wroblewski, Linda Wolff et al. · 2012 · Proceedings of the National Academy of Sciences
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- Targeting Epigenetic protein–protein Interactions With small-molecule InhibitorsBrian M. Linhares, Jolanta E. Grembecka, Tomasz Cierpicki · 2020 · Future Medicinal Chemistry
- The Role of RhoH in TCR Signalling and Its Involvement in DiseasesAhmad Mokhtar, Ana Masara, Hashim, Ilie Fadzilah, Mohd Zaini Makhtar, Muaz, Salikin, Nor Hawani, Amin-Nordin, Syafinaz · 2021 · Cells
- Molecular classification and therapeutics in diffuse large B-cell lymphomaGaelen Shimkus, T. NONAKA · 2023 · Frontiers in Molecular Biosciences
- Gammaherpesviruses and B Cells: A Relationship That Lasts a LifetimeKaitlin E. Johnson, Vera L. Tarakanova · 2020 · Viral Immunology
- Dysregulation of miRNAs in DLBCL: Causative Factor for Pathogenesis, Diagnosis and PrognosisMohammed Alsaadi, Muhammad Yasir Khan, Mahmood Hassan Dalhat, Salem Bahashwan, Muhammad Uzair Khan, Abdulgader H. Albar, Hussein A. Almehdar, Ishtiaq Qadri · 2021 · Diagnostics
- Gene Interaction Network Regulates Plasma Cell DifferentiationJukka Alinikula, Olli Lassila · 2011 · Scandinavian Journal of Immunology
- Rewired NFκB signaling as a potentially actionable feature of activated B‐cell‐like diffuse large B‐cell lymphomaGero Knittel, Paul Liedgens, Darya Korovkina, Christian Philipp Pallasch, Hans Christian Reinhardt · 2016 · European Journal Of Haematology